Hypothesis

28 Matching Annotations

Oct 2025
54.241.53.176 54.241.53.176

1-s2.0-S0014488625003863-main-html.html

1
1. scibot 23 Oct 2025
  
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  RRID:AB_306069
  
  DOI: 10.1016/j.expneurol.2025.115521
  
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54.241.53.176/fc5e10bd35ff62b2b21d4c1c21c2cc54900220b7/1-s2.0-S0014488625003863-main-html.html
May 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

mTOR inhibition in Q175 Huntington’s disease model mice facilitates neuronal autophagy and mutant huntingtin clearance

1
1. scibot 22 May 2025
  
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  RRID:AB_306069
  
  DOI: 10.7554/eLife.104979
  
  Resource: (Abcam Cat# ab7780, RRID:AB_306069)
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12092004/
www.sciencedirect.com www.sciencedirect.com

Covalent inhibition of Plasmodium falciparum Ubc13 impairs global protein synthesis

1
1. scibot 22 May 2025
  
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  RRID:AB_306069
  
  DOI: 10.1016/j.isci.2025.112545
  
  Resource: (Abcam Cat# ab7780, RRID:AB_306069)
  
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sciencedirect.com/science/article/pii/S2589004225008065
Feb 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Differential effects of moderate chronic ethanol consumption on neurobehavior, white matter glial protein expression, and mTOR pathway signaling with adolescent brain maturation

1
1. scibot 15 Feb 2025
  
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  AB_306069
  
  DOI: 10.1080/00952990.2024.2355540
  
  Resource: (Abcam Cat# ab7780, RRID:AB_306069)
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11824867/
Jul 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Rapid iPSC inclusionopathy models shed light on formation, consequence, and molecular subtype of α-synuclein inclusions

1
1. scibot 30 Jul 2024
  
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  AB_306069
  
  DOI: 10.1016/j.neuron.2024.06.002
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11377155/
Jun 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Multiomic ALS signatures highlight subclusters and sex differences suggesting the MAPK pathway as therapeutic target

1
1. scibot 13 Jun 2024
  
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  RRID:AB_306069
  
  DOI: 10.1038/s41467-024-49196-y
  
  Resource: (Abcam Cat# ab7780, RRID:AB_306069)
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11161513/
Feb 2024
www.sciencedirect.com www.sciencedirect.com

Prenatal hormone stress triggers embryonic cardiac hypertrophy outcome by ubiquitin-dependent degradation of mitochondrial mitofusin 2

1
1. scibot 09 Feb 2024
  
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  RRID:AB_306069
  
  DOI: 10.1016/j.isci.2023.108690
  
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sciencedirect.com/science/article/pii/S2589004223027670
Aug 2023
www.biorxiv.org www.biorxiv.org

Multiomic ALS signatures highlight sex differences and molecular subclusters and identify the MAPK pathway as therapeutic target

1
1. scibot 29 Aug 2023
  
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  RRID:AB_306069
  
  DOI: 10.1101/2023.08.14.553180
  
  Resource: (Abcam Cat# ab7780, RRID:AB_306069)
  
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biorxiv.org/content/10.1101/2023.08.14.553180v1
Jun 2023
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Acetylation halts missense mutant p53 aggregation and rescues tumor suppression in non-small cell lung cancers

1
1. scibot 16 Jun 2023
  
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  RRID:AB_306069
  
  DOI: 10.1016/j.isci.2023.107003
  
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sciencedirect.com/science/article/pii/S2589004223010805
May 2023
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Differential Early Mechanistic Frontal Lobe Responses to Choline Chloride and Soy Isoflavones in an Experimental Model of Fetal Alcohol Spectrum Disorder

1
1. scibot 04 May 2023
  
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  AB_306069
  
  DOI: 10.3390/ijms24087595
  
  Resource: (Abcam Cat# ab7780, RRID:AB_306069)
  
  Curator: @scibot
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10145811/
Dec 2022
www.sciencedirect.com www.sciencedirect.com

AKTIP loss is enriched in ERα-positive breast cancer for tumorigenesis and confers endocrine resistance

1
1. scibot 18 Dec 2022
  
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  RRID:AB_306069
  
  DOI: 10.1016/j.celrep.2022.111821
  
  Resource: (Abcam Cat# ab7780, RRID:AB_306069)
  
  Curator: @scibot
  
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sciencedirect.com/science/article/pii/S2211124722017132
Dec 2021
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Proteostasis regulated by testis-specific ribosomal protein RPL39L maintains mouse spermatogenesis

1
1. scibot 02 Dec 2021
  
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  RRID:AB_306069
  
  DOI: 10.1016/j.isci.2021.103396
  
  Resource: (Abcam Cat# ab7780, RRID:AB_306069)
  
  Curator: @scibot
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8605100/
Sep 2021
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

ACLY ubiquitination by CUL3-KLHL25 induces the reprogramming of fatty acid metabolism to facilitate iTreg differentiation

1
1. scibot 11 Sep 2021
  
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  RRID:AB_306069
  
  DOI: 10.7554/eLife.62394
  
  Resource: (Abcam Cat# ab7780, RRID:AB_306069)
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8423445/
Aug 2021
www.sciencedirect.com www.sciencedirect.com

Lethal Poisoning of Cancer Cells by Respiratory Chain Inhibition plus Dimethyl α-Ketoglutarate

1
1. scibot 01 Aug 2021
  
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  RRID:AB_306069
  
  DOI: 10.1016/j.celrep.2019.03.058
  
  Resource: (Abcam Cat# ab7780, RRID:AB_306069)
  
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sciencedirect.com/science/article/pii/S2211124719303882
Jul 2021
www.sciencedirect.com www.sciencedirect.com

NPGPx-Mediated Adaptation to Oxidative Stress Protects Motor Neurons from Degeneration in Aging by Directly Modulating O-GlcNAcase

1
1. scibot 29 Jul 2021
  
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  RRID:AB_306069
  
  DOI: 10.1016/j.celrep.2019.10.053
  
  Resource: (Abcam Cat# ab7780, RRID:AB_306069)
  
  Curator: @ethanbadger
  
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sciencedirect.com/science/article/pii/S2211124719313671
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

The optineurin/TIA1 pathway inhibits aberrant stress granule formation and reduces ubiquitinated TDP-43

1
1. scibot 14 Jul 2021
  
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  AB_306069
  
  DOI: 10.1016/j.isci.2021.102733
  
  Resource: (Abcam Cat# ab7780, RRID:AB_306069)
  
  Curator: @scibot
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8259439/
www.sciencedirect.com www.sciencedirect.com

Loss of TRIM21 alleviates cardiotoxicity by suppressing ferroptosis induced by the chemotherapeutic agent doxorubicin

1
1. scibot 07 Jul 2021
  
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  RRID:AB_306069
  
  DOI: 10.1016/j.ebiom.2021.103456
  
  Resource: (Abcam Cat# ab7780, RRID:AB_306069)
  
  Curator: @scibot
  
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sciencedirect.com/science/article/pii/S2352396421002498
May 2021
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

HDAC1 SUMOylation promotes Argonaute-directed transcriptional silencing in C. elegans

1
1. scibot 21 May 2021
  
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  RRID:AB_306069
  
  DOI: 10.7554/eLife.63299
  
  Resource: (Abcam Cat# ab7780, RRID:AB_306069)
  
  Curator: @scibot
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8131101/
Feb 2021
www.sciencedirect.com www.sciencedirect.com

OTUB1 Is a Key Regulator of RIG-I-Dependent Immune Signaling and Is Targeted for Proteasomal Degradation by Influenza A NS1

1
1. scibot 24 Feb 2021
  
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  RRID:AB_306069
  
  DOI: 10.1016/j.celrep.2020.01.015
  
  Resource: (Abcam Cat# ab7780, RRID:AB_306069)
  
  Curator: @scibot
  
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sciencedirect.com/science/article/pii/S2211124720300243
Nov 2020
www.sciencedirect.com www.sciencedirect.com

Characterization of Small-Molecule-Induced Changes in Parkinson's-Related Trafficking via the Nedd4 Ubiquitin Signaling Cascade

1
1. scibot 24 Nov 2020
  
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  RRID:AB_306069
  
  DOI: 10.1016/j.chembiol.2020.10.008
  
  Resource: (Abcam Cat# ab7780, RRID:AB_306069)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:AB_306069
  
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  RRIDCUR:Validated RRID:AB_306069
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RRID:AB_306069

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scibot

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sciencedirect.com/science/article/pii/S2451945620304244
Sep 2020
www.sciencedirect.com www.sciencedirect.com

The Dynein Adaptor RILP Controls Neuronal Autophagosome Biogenesis, Transport, and Clearance

1
1. scibot 23 Sep 2020
  
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  RRID:AB_306069
  
  DOI: 10.1016/j.devcel.2020.03.011
  
  Resource: (Abcam Cat# ab7780, RRID:AB_306069)
  
  Curator: @ethanbadger
  
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  RRID:AB_306069 RRIDCUR:Validated
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sciencedirect.com/science/article/pii/S1534580720302185
www.sciencedirect.com www.sciencedirect.com

OTUB1 Is a Key Regulator of RIG-I-Dependent Immune Signaling and Is Targeted for Proteasomal Degradation by Influenza A NS1

1
1. scibot 08 Sep 2020
  
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  RRID:AB_306069
  
  DOI: 10.1016/j.celrep.2020.01.015
  
  Resource: (Abcam Cat# ab7780, RRID:AB_306069)
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:AB_306069
  
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  RRID:AB_306069 RRIDCUR:Validated
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sciencedirect.com/science/article/pii/S2211124720300243
Jan 2020
www.sciencedirect.com www.sciencedirect.com

A PRMT5-RNF168-SMURF2 Axis Controls H2AX Proteostasis

1
1. scibot 13 Jan 2020
  
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  RRID:AB_306069
  
  DOI: 10.1016/j.celrep.2019.08.031
  
  Resource: (Abcam Cat# ab7780, RRID:AB_306069)
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:AB_306069
  
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  RRID:AB_306069 RRIDCUR:Validated
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sciencedirect.com/science/article/pii/S2211124719310654
Nov 2018
www.sciencedirect.com www.sciencedirect.com

A Designed Peptide Targets Two Types of Modifications of p53 with Anti-cancer Activity

1
1. scibot 05 Nov 2018
  
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  ab7780
  
  Curator: @Jmenke
  
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  (Abcam Cat# ab7780, RRID:AB_306069)
  
  SciCrunch record: RRID:AB_306069
  
  Alternate resolvers: SciCrunch xml N2T identifiers.org
  
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  RRID:AB_306069 RRIDCUR:Missing
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scibot

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sciencedirect.com/science/article/pii/S2451945618301120
content.iospress.com content.iospress.com

Amyloid-β Induces AMPA Receptor Ubiquitination and Degradation in Primary Neurons and Human Brains of Alzheimer’s Disease

1
1. scibot 05 Nov 2018
  
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  RRID:AB_306069
  
  Curator: @evieth
  
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  (Abcam Cat# ab7780, RRID:AB_306069)
  
  SciCrunch record: RRID:AB_306069
  
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  RRID:AB_306069 RRIDCUR:Validated
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RRIDCUR:Validated

RRID:AB_306069

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scibot

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content.iospress.com/articles/journal-of-alzheimers-disease/jad170879
www.sciencedirect.com www.sciencedirect.com

Age-Dependent Dopaminergic Neurodegeneration and Impairment of the Autophagy-Lysosomal Pathway in LRRK-Deficient Mice

1
1. scibot 05 Nov 2018
  
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  RRID:AB_306069
  
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sciencedirect.com/science/article/pii/S0896627317309054
Nov 2017
www.sciencedirect.com www.sciencedirect.com

TTC19 Plays a Husbandry Role on UQCRFS1 Turnover in the Biogenesis of Mitochondrial Respiratory Complex III

1
1. scibot 08 Nov 2017
  
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  AB_306069
  
  Curator: @chewbeccax
  
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  (Abcam Cat# ab7780, RRID:AB_306069)
  
  SciCrunch record: RRID:AB_306069
  
  Alternate resolvers: SciCrunch xml N2T identifiers.org
  
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  RRID:AB_306069 RRIDCUR:Validated
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sciencedirect.com/science/article/pii/S1097276517304033
onlinelibrary.wiley.com onlinelibrary.wiley.com

Changes in the expression of collapsin response mediator protein‐2 during synaptic plasticity in the mouse hippocampus

1
1. scibot 08 Nov 2017
  
  in Public
  
  AB_306069
  
  Curator: @gabimpine
  
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  (Abcam Cat# ab7780, RRID:AB_306069)
  
  SciCrunch record: RRID:AB_306069
  
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  RRID:AB_306069 RRIDCUR:Validated
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onlinelibrary.wiley.com/doi/10.1002/jnr.23626/full