48 Matching Annotations
  1. Jul 2024
  2. www.sciencedirect.com www.sciencedirect.com
    An IDR-dependent mechanism for nuclear receptor control of Mediator interaction with RNA polymerase II
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    1. scibot 19 Jul 2024
      AB_306327

      DOI: 10.1016/j.molcel.2024.06.006

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    sciencedirect.com/science/article/pii/S1097276524004842
  3. Mar 2024
  4. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The winged helix domain of MORF binds CpG islands and the TAZ2 domain of p300
    1
    1. scibot 22 Mar 2024
      RRID:AB_306327

      DOI: 10.1016/j.isci.2024.109367

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    ncbi.nlm.nih.gov/pmc/articles/PMC10946326/
  5. Nov 2023
  6. www.nature.com www.nature.com
    Selective inhibition of CDK9 in triple negative breast cancer
    1
    1. scibot 25 Nov 2023
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      DOI: 10.1038/s41388-023-02892-3

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    nature.com/articles/s41388-023-02892-3
  7. Jul 2023
  8. www.sciencedirect.com www.sciencedirect.com
    Bacterial effector restricts liquid-liquid phase separation of ZPR1 to antagonize host UPRER
    1
    1. scibot 05 Jul 2023
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      DOI: 10.1016/j.celrep.2023.112700

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    sciencedirect.com/science/article/pii/S2211124723007118
  9. May 2023
  10. www.sciencedirect.com www.sciencedirect.com
    Functional interplay between Mediator and RSC chromatin remodeling complex controls nucleosome-depleted region maintenance at promoters
    1
    1. scibot 03 May 2023
      RRID:AB_306327

      DOI: 10.1016/j.celrep.2023.112465

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    sciencedirect.com/science/article/pii/S221112472300476X
  11. Apr 2023
  12. www.sciencedirect.com www.sciencedirect.com
    USP9X mediates an acute adaptive response to MAPK suppression in pancreatic cancer but creates multiple actionable therapeutic vulnerabilities
    1
    1. scibot 08 Apr 2023
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      DOI: 10.1016/j.xcrm.2023.101007

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    sciencedirect.com/science/article/pii/S2666379123001179
  13. Jan 2023
  14. www.embopress.org www.embopress.org
    C. elegans molting requires rhythmic accumulation of the Grainyhead/LSF transcription factor GRH-1
    1
    1. scibot 27 Jan 2023
      RRID:AB_306327

      DOI: 10.15252/embj.2022111895

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    embopress.org/doi/10.15252/embj.2022111895
  15. www.sciencedirect.com www.sciencedirect.com
    MDC1 maintains active elongation complexes of RNA polymerase II
    1
    1. scibot 19 Jan 2023
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      DOI: 10.1016/j.celrep.2022.111979

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    sciencedirect.com/science/article/pii/S2211124722018836
  16. Oct 2022
  17. www.sciencedirect.com www.sciencedirect.com
    Topoisomerases I and II facilitate condensin DC translocation to organize and repress X chromosomes in C. elegans
    1
    1. scibot 27 Oct 2022
      RRID:AB_306327

      DOI: 10.1016/j.molcel.2022.10.002

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    sciencedirect.com/science/article/pii/S1097276522009595
  18. Aug 2022
  19. www.sciencedirect.com www.sciencedirect.com
    The BASP1 transcriptional corepressor modifies chromatin through lipid-dependent and lipid-independent mechanisms
    1
    1. scibot 17 Aug 2022
      RRID:AB_306327

      DOI: 10.1016/j.isci.2022.104796

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    sciencedirect.com/science/article/pii/S2589004222010689
  20. www.sciencedirect.com www.sciencedirect.com
    A lncRNA fine-tunes salicylic acid biosynthesis to balance plant immunity and growth
    1
    1. scibot 04 Aug 2022
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      DOI: 10.1016/j.chom.2022.07.001

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    sciencedirect.com/science/article/pii/S1931312822003171
  21. Feb 2022
  22. www.sciencedirect.com www.sciencedirect.com
    The landscape of pioneer factor activity reveals the mechanisms of chromatin reprogramming and genome activation
    1
    1. scibot 23 Feb 2022
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      DOI: 10.1016/j.molcel.2022.01.024

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    sciencedirect.com/science/article/pii/S1097276522001009
  23. Nov 2021
  24. www.sciencedirect.com www.sciencedirect.com
    Impaired glucocorticoid receptor expression in liver disrupts feeding-induced gene expression, glucose uptake, and glycogen storage
    1
    1. scibot 03 Nov 2021
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      DOI: 10.1016/j.celrep.2021.109938

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    sciencedirect.com/science/article/pii/S221112472101411X
  25. Sep 2021
  26. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    HBO1-MLL interaction promotes AF4/ENL/P-TEFb-mediated leukemogenesis
    1
    1. scibot 04 Sep 2021
      RRID:AB_306327

      DOI: 10.7554/eLife.65872

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    ncbi.nlm.nih.gov/pmc/articles/PMC8387021/
  27. Aug 2021
  28. www.sciencedirect.com www.sciencedirect.com
    Untitled document
    1
    1. scibot 10 Aug 2021
      RRID:AB_306327

      DOI: 10.1016/j.devcel.2018.11.046

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    sciencedirect.com/science/article/pii/S153458071831030X
  29. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Untitled document
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    1. scibot 04 Aug 2021
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      DOI: 10.1016/j.molcel.2019.01.033

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    ncbi.nlm.nih.gov/pmc/articles/PMC6482433/
  30. Jul 2021
  31. www.sciencedirect.com www.sciencedirect.com
    Establishment, maintenance, and recall of inflammatory memory
    1
    1. scibot 30 Jul 2021
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      DOI: 10.1016/j.stem.2021.07.001

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    sciencedirect.com/science/article/pii/S1934590921002861
  32. www.sciencedirect.com www.sciencedirect.com
    The Transcriptionally Permissive Chromatin State of Embryonic Stem Cells Is Acutely Tuned to Translational Output
    1
    1. scibot 30 Jul 2021
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      DOI: 10.1016/j.stem.2018.02.004

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    sciencedirect.com/science/article/pii/S1934590918300663
  33. www.sciencedirect.com www.sciencedirect.com
    Targeting CDK9 Reactivates Epigenetically Silenced Genes in Cancer
    1
    1. scibot 30 Jul 2021
      RRID:AB_306327

      DOI: 10.1016/j.cell.2018.09.051

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    sciencedirect.com/science/article/pii/S0092867418312637
  34. www.sciencedirect.com www.sciencedirect.com
    A Pliable Mediator Acts as a Functional Rather Than an Architectural Bridge between Promoters and Enhancers
    1
    1. scibot 29 Jul 2021
      RRID: AB_306327

      DOI: 10.1016/j.cell.2019.07.011

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    sciencedirect.com/science/article/pii/S0092867419307767
  35. academic.oup.com academic.oup.com
    GADD45a Promotes Active DNA Demethylation of the MMP-9 Promoter via Base Excision Repair Pathway in AGEs-Treated Keratinocytes and in Diabetic Male Rat Skin
    2
    1. scibot 29 Jul 2021
      AB_306327

      DOI: 10.1210/en.2017-00686

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    2. scibot 29 Jul 2021
      AB_306327

      DOI: 10.1210/en.2017-00686

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    academic.oup.com/endo/article/159/2/1172/4736306
  36. www.sciencedirect.com www.sciencedirect.com
    Neuronal activity-induced BRG1 phosphorylation regulates enhancer activation
    1
    1. scibot 14 Jul 2021
      AB_306327

      DOI: 10.1016/j.celrep.2021.109357

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    sciencedirect.com/science/article/pii/S2211124721007555
  37. May 2021
  38. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    ZC3H4 restricts non-coding transcription in human cells
    1
    1. scibot 26 May 2021
      AB_306327

      DOI: 10.7554/eLife.67305

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    ncbi.nlm.nih.gov/pmc/articles/PMC8137146/
  39. www.sciencedirect.com www.sciencedirect.com
    The PP2A-Integrator-CDK9 axis fine-tunes transcription and can be targeted therapeutically in cancer
    1
    1. scibot 18 May 2021
      RRID:AB_306327

      DOI: 10.1016/j.cell.2021.04.022

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    sciencedirect.com/science/article/pii/S009286742100502X
  40. www.sciencedirect.com www.sciencedirect.com
    Enhancers are activated by p300/CBP activity-dependent PIC assembly, RNAPII recruitment, and pause release
    1
    1. scibot 08 May 2021
      RRID:AB_306327

      DOI: 10.1016/j.molcel.2021.03.008

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    sciencedirect.com/science/article/pii/S1097276521001763
  41. www.sciencedirect.com www.sciencedirect.com
    Interferon-γ induces tumor resistance to anti-PD-1 immunotherapy by promoting YAP phase separation
    1
    1. scibot 08 May 2021
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      DOI: 10.1016/j.molcel.2021.01.010

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    sciencedirect.com/science/article/pii/S1097276521000101
  42. www.sciencedirect.com www.sciencedirect.com
    A Role for the Mre11-Rad50-Xrs2 Complex in Gene Expression and Chromosome Organization
    1
    1. scibot 08 May 2021
      RRID:AB_306327

      DOI: 10.1016/j.molcel.2020.11.010

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    sciencedirect.com/science/article/pii/S1097276520307887
  43. Apr 2021
  44. www.sciencedirect.com www.sciencedirect.com
    Transcriptional control of DNA repair networks by CDK7 regulates sensitivity to radiation in MYC-driven medulloblastoma
    1
    1. scibot 28 Apr 2021
      RRID:AB_306327

      DOI: 10.1016/j.celrep.2021.109013

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    sciencedirect.com/science/article/pii/S2211124721003272
  45. Feb 2021
  46. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Discovery of a molecular glue promoting CDK12-DDB1 interaction to trigger cyclin K degradation
    1
    1. scibot 26 Feb 2021
      RRID:AB_306327

      DOI: 10.7554/eLife.59994

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    ncbi.nlm.nih.gov/pmc/articles/PMC7462607/
  47. Jan 2021
  48. www.sciencedirect.com www.sciencedirect.com
    MRE11-RAD50-NBS1 Complex Is Sufficient to Promote Transcription by RNA Polymerase II at Double-Strand Breaks by Melting DNA Ends
    1
    1. scibot 08 Jan 2021
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      DOI: 10.1016/j.celrep.2020.108565

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    sciencedirect.com/science/article/pii/S2211124720315540
  49. Dec 2020
  50. www.sciencedirect.com www.sciencedirect.com
    RTEL1 Regulates G4/R-Loops to Avert Replication-Transcription Collisions
    1
    1. scibot 23 Dec 2020
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      DOI: 10.1016/j.celrep.2020.108546

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    sciencedirect.com/science/article/pii/S2211124720315357
  51. Nov 2020
  52. www.cell.com www.cell.com
    Formation of the CenH3-Deficient Holocentromere in Lepidoptera Avoids Active Chromatin
    1
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      DOI: 10.1016/j.cub.2020.09.078

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    cell.com/current-biology/abstract/S0960-9822(20)31448-2
  53. www.sciencedirect.com www.sciencedirect.com
    G9a Promotes Breast Cancer Recurrence through Repression of a Pro-inflammatory Program
    1
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      DOI: 10.1016/j.celrep.2020.108341

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    sciencedirect.com/science/article/pii/S2211124720313309
  54. Sep 2020
  55. www.sciencedirect.com www.sciencedirect.com
    Activation of CpG-Rich Promoters Mediated by MLL Drives MOZ-Rearranged Leukemia
    1
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      DOI: 10.1016/j.celrep.2020.108200

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    sciencedirect.com/science/article/pii/S221112472031189X
  56. www.sciencedirect.com www.sciencedirect.com
    Cell Type-Specific Intralocus Interactions Reveal Oligodendrocyte Mechanisms in MS
    1
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      DOI: 10.1016/j.cell.2020.03.002

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    sciencedirect.com/science/article/pii/S0092867420302646
  57. www.sciencedirect.com www.sciencedirect.com
    Critical Roles of Translation Initiation and RNA Uridylation in Endogenous Retroviral Expression and Neural Differentiation in Pluripotent Stem Cells
    1
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      DOI: 10.1016/j.celrep.2020.107715

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    sciencedirect.com/science/article/pii/S2211124720306926
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    Enhancer RNAs Mediate Estrogen-Induced Decommissioning of Selective Enhancers by Recruiting ERα and Its Cofactor
    1
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      DOI: 10.1016/j.celrep.2020.107803

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    sciencedirect.com/science/article/pii/S2211124720307841
  59. Jan 2020
  60. elifesciences.org elifesciences.org
    Tyr1 phosphorylation promotes phosphorylation of Ser2 on the C-terminal domain of eukaryotic RNA polymerase II by P-TEFb
    1
    1. scibot 13 Jan 2020
      RRID:AB_306327

      DOI: 10.7554/eLife.48725

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    elifesciences.org/articles/48725
  61. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Untitled document
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      DOI: 10.7554/eLife.40806

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    ncbi.nlm.nih.gov/pmc/articles/PMC6335052/
  62. www.sciencedirect.com www.sciencedirect.com
    Untitled document
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    1. scibot 13 Jan 2020
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      DOI: 10.1016/j.molcel.2019.01.033

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    sciencedirect.com/science/article/pii/S109727651930053X
  63. Nov 2018
  64. www.sciencedirect.com www.sciencedirect.com
    Arabidopsis ARGONAUTE 1 Binds Chromatin to Promote Gene Transcription in Response to Hormones and Stresses
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    1. scibot 05 Nov 2018
      RRID:AB_306327

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    sciencedirect.com/science/article/pii/S1534580717309875
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    Different Neuronal Activity Patterns Induce Different Gene Expression Programs
    1
    1. scibot 05 Nov 2018
      RRID:AB_306327

      Curator: @anp055

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      (Abcam Cat# ab817, RRID:AB_306327)

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    sciencedirect.com/science/article/pii/S089662731830285X
  66. www.sciencedirect.com www.sciencedirect.com
    Early-Life Gene Expression in Neurons Modulates Lasting Epigenetic States
    1
    1. scibot 05 Nov 2018
      RRID:AB_306327

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      (Abcam Cat# ab817, RRID:AB_306327)

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    sciencedirect.com/science/article/pii/S0092867417311418
  67. Nov 2017
  68. www.sciencedirect.com www.sciencedirect.com
    Non-coding Transcription Instructs Chromatin Folding and Compartmentalization to Dictate Enhancer-Promoter Communication and T Cell Fate
    1
    1. scibot 08 Nov 2017
      RRID:AB_306327

      Curator: @Jmenke

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      (Abcam Cat# ab817, RRID:AB_306327)

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    sciencedirect.com/science/article/pii/S0092867417310504
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    Telomere Length Determines TERRA and R-Loop Regulation through the Cell Cycle
    1
    1. scibot 08 Nov 2017
      AB_306327

      Curator: @chewbeccax

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      (Abcam Cat# ab817, RRID:AB_306327)

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    sciencedirect.com/science/article/pii/S0092867417306475
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    BTBD18 Regulates a Subset of piRNA-Generating Loci through Transcription Elongation in Mice
    1
    1. scibot 08 Nov 2017
      AB_306327

      Curator: @kaitlinsung

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      (Abcam Cat# ab817, RRID:AB_306327)

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    sciencedirect.com/science/article/pii/S153458071730076X
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    s-Adenosylmethionine Levels Govern Innate Immunity through Distinct Methylation-Dependent Pathways
    1
    1. scibot 08 Nov 2017
      AB_306327

      Curator: @jcabotaj

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      (Abcam Cat# ab817, RRID:AB_306327)

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    sciencedirect.com/science/article/pii/S1550413115003423