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Aug 2025
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Promoter- and enhancer-dependent cohesin loading initiates chromosome looping to fold Tcrb loci for long-range recombination

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1. scibot 19 Aug 2025
  
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  DOI: 10.1016/j.celrep.2025.116133
  
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sciencedirect.com/science/article/pii/S2211124725009040
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

The catalytic efficiency of METTL16 affects cellular processes by governing the intracellular S-adenosylmethionine setpoint

1
1. scibot 10 Aug 2025
  
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  DOI: 10.1016/j.celrep.2025.115966
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12330366/
Jul 2025
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The catalytic efficiency of METTL16 affects cellular processes by governing the intracellular S-adenosylmethionine setpoint

1
1. scibot 15 Jul 2025
  
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  DOI: 10.1016/j.celrep.2025.115966
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12330366/
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The histone variant H3.14 is an early player in the abiotic stress response of Arabidopsis

1
1. scibot 09 Jul 2025
  
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  DOI: 10.1016/j.devcel.2025.06.019
  
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sciencedirect.com/science/article/pii/S1534580725003740
Jun 2025
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Regulation of somatic hypermutation by higher-order chromatin structure

1
1. scibot 28 Jun 2025
  
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  DOI: 10.1016/j.molcel.2025.06.003
  
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sciencedirect.com/science/article/pii/S1097276525005039
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Epigenetic regulation of intracellular branched-chain amino acid homeostasis maintains a normal lifespan

1
1. scibot 28 Jun 2025
  
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  RRID:AB_3066649
  
  DOI: 10.1016/j.isci.2025.112846
  
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sciencedirect.com/science/article/pii/S2589004225011071
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HBO1 functions as an epigenetic barrier to hepatocyte plasticity and reprogramming during liver injury

1
1. scibot 24 Jun 2025
  
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  DOI: 10.1016/j.stem.2025.04.010
  
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cell.com/cell-stem-cell/abstract/S1934-5909(25)00177-8
52.53.155.43 52.53.155.43

PDF-html.html

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1. scibot 17 Jun 2025
  
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  DOI: 10.1158/2159-8290.cd-24-1904
  
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52.53.155.43/fedd6ccff8c0b6494dbe8595a0c800e33e0860f7/PDF-html.html
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Combined inhibition of KAT6A/B and Menin reverses estrogen receptor-driven gene expression programs in breast cancer

1
1. scibot 14 Jun 2025
  
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  DOI: 10.1016/j.xcrm.2025.102192
  
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sciencedirect.com/science/article/pii/S2666379125002654
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Ezh2 Delays Activation of Differentiation Genes During Normal Cerebellar Granule Neuron Development and in Medulloblastoma

1
1. scibot 11 Jun 2025
  
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  DOI: 10.7554/eLife.105339.1
  
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elifesciences.org/reviewed-preprints/105339v1
May 2025
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Division of labor among H3K4 methyltransferases defines distinct facets of homeostatic plasticity

1
1. scibot 22 May 2025
  
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  DOI: 10.1016/j.celrep.2025.115746
  
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sciencedirect.com/science/article/pii/S2211124725005170
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Heterozygous Kmt2d loss diminishes enhancers to render medulloblastoma cells vulnerable to combinatory inhibition of LSD1 and OXPHOS

1
1. scibot 16 May 2025
  
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  AB_306649
  
  DOI: 10.1016/j.celrep.2025.115619
  
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sciencedirect.com/science/article/pii/S2211124725003900
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Functional characterization of the ATOH1 molecular subtype indicates a pro-metastatic role in small cell lung cancer

1
1. scibot 16 May 2025
  
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  DOI: 10.1016/j.celrep.2025.115603
  
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sciencedirect.com/science/article/pii/S2211124725003742
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Shigella-trained pro-inflammatory macrophages protect zebrafish from secondary infection

1
1. scibot 16 May 2025
  
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  DOI: 10.1016/j.celrep.2025.115601
  
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sciencedirect.com/science/article/pii/S2211124725003729
Apr 2025
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The establishment of nuclear organization in mouse embryos is orchestrated by multiple epigenetic pathways

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1. scibot 24 Apr 2025
  
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  DOI: 10.1016/j.cell.2025.03.044
  
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sciencedirect.com/science/article/pii/S0092867425003964
faseb.onlinelibrary.wiley.com faseb.onlinelibrary.wiley.com

Targeting MLL1/WDR5-Mediated Epigenetic Regulation Mitigates Peritoneal Fibrosis by Reducing p16INK4a

1
1. scibot 17 Apr 2025
  
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  DOI: 10.1096/fj.202402382R
  
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faseb.onlinelibrary.wiley.com/doi/10.1096/fj.202402382R
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SWI/SNF complex-mediated ZNF410 cooperative binding maintains chromatin accessibility and enhancer activity

1
1. scibot 02 Apr 2025
  
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  DOI: 10.1016/j.celrep.2025.115476
  
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cell.com/cell-reports/fulltext/S2211-1247(25)00247-5
Mar 2025
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1-s2.0-S258900422500536X-main-html.html

1
1. scibot 29 Mar 2025
  
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  RRID:1083744-1
  
  DOI: 10.1016/j.isci.2025.112275
  
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52.53.155.43/20fb93250db4f2d7fdfa7182e1f229b229b7142f/1-s2.0-S258900422500536X-main-html.html
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Mechanical Loading Induces NRF2 Nuclear Translocation to Epigenetically Remodel Oxidative Stress Defense in Osteocytes

1
1. scibot 28 Mar 2025
  
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  RRID:AB_306649
  
  DOI: 10.3390/antiox14030346
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11939503/
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Eye features and retinal photoreceptors of the nocturnal aardvark (Orycteropus afer, Tubulidentata)

1
1. scibot 27 Mar 2025
  
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  DOI: 10.1371/journal.pone.0314252
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11932471/
Feb 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Histone H4 acetylation differentially modulates proliferation in adult oligodendrocyte progenitors

1
1. scibot 13 Feb 2025
  
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  RRID:AB_306649
  
  DOI: 10.1083/jcb.202308064
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11318668/
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KMT2C/KMT2D-dependent H3K4me1 mediates changes in DNA replication timing and origin activity during a cell fate transition

1
1. scibot 06 Feb 2025
  
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  AB_306649
  
  DOI: 10.1016/j.celrep.2025.115272
  
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sciencedirect.com/science/article/pii/S2211124725000439
Jan 2025
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Nucleosomal asymmetry shapes histone mark binding and promotes poising at bivalent domains

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1. scibot 03 Jan 2025
  
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  RRID:AB_306649
  
  DOI: 10.1016/j.molcel.2024.12.002
  
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sciencedirect.com/science/article/pii/S1097276524009973
Dec 2024
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Transcriptional memory drives accelerated re-activation of several biosynthetic gene clusters in Aspergillus nidulans.

1
1. scibot 06 Dec 2024
  
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  RRID:AB_306649
  
  DOI: 10.1016/j.micres.2024.127981
  
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sciencedirect.com/science/article/pii/S0944501324003823
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Drosophila Piwi distinguishes transposons from mRNAs by piRNA complementarity and abundance

1
1. scibot 05 Dec 2024
  
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  RRID:AB_306649
  
  DOI: 10.1016/j.celrep.2024.115020
  
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sciencedirect.com/science/article/pii/S2211124724013718
Nov 2024
elifesciences.org elifesciences.org

The E3 ubiquitin ligase RNF220 maintains hindbrain Hox expression patterns through regulation of WDR5 stability

1
1. scibot 14 Nov 2024
  
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  RRID:AB_306649
  
  DOI: 10.7554/eLife.94657
  
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elifesciences.org/articles/94657
Oct 2024
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Midkine as a driver of age-related changes and increase in mammary tumorigenesis

1
1. scibot 04 Oct 2024
  
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  AB_306649
  
  DOI: 10.1016/j.ccell.2024.09.002
  
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sciencedirect.com/science/article/pii/S1535610824003507
Sep 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Control of epigenomic landscape and development of fetal male germ cells through L-serine metabolism

1
1. scibot 26 Sep 2024
  
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  RRID:AB_306649
  
  DOI: 10.1016/j.isci.2024.110702
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11388182/
Aug 2024
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Redox heterogeneity in mouse embryonic stem cells individualizes cell fate decisions

1
1. scibot 19 Aug 2024
  
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  RRID:AB_306649
  
  DOI: 10.1016/j.devcel.2024.07.008
  
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sciencedirect.com/science/article/pii/S1534580724004453
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A replisome-associated histone H3-H4 chaperone required for epigenetic inheritance

1
1. scibot 18 Aug 2024
  
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  AB_306649
  
  DOI: 10.1016/j.cell.2024.07.006
  
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sciencedirect.com/science/article/pii/S0092867424007669
Jul 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

ZNF397 Deficiency Triggers TET2-Driven Lineage Plasticity and AR-Targeted Therapy Resistance in Prostate Cancer

2
1. scibot 31 Jul 2024
  
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  RRID:AB_306649
  
  DOI: 10.1158/2159-8290.CD-23-0539
  
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  RRID:AB_306649
  
  DOI: 10.1158/2159-8290.CD-23-0539
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11285331/
www.cell.com www.cell.com

YY1-mediated enhancer-promoter communication in the immunoglobulin μ locus is regulated by MSL/MOF recruitment

1
1. scibot 16 Jul 2024
  
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  RRID:AB_306649
  
  DOI: 10.1016/j.celrep.2024.114456
  
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cell.com/cell-reports/abstract/S2211-1247(24)00785-X
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

The COMPASS complex maintains the metastatic capacity imparted by a subpopulation of cells in UPS

1
1. scibot 14 Jul 2024
  
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  RRID:AB_306649
  
  DOI: 10.1016/j.isci.2024.110187
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11233968/
Jun 2024
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Hypoxia-induced CTCF promotes EMT in breast cancer

1
1. scibot 21 Jun 2024
  
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  RRID:AB_306649
  
  DOI: 10.1016/j.celrep.2024.114367
  
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sciencedirect.com/science/article/pii/S2211124724006958
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Capturing totipotency in human cells through spliceosomal repression

1
1. scibot 06 Jun 2024
  
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  DOI: 10.1016/j.cell.2024.05.010
  
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sciencedirect.com/science/article/pii/S0092867424005191
May 2024
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Reduced histone H3K4 trimethylation in oral mucosa of patients with DYT-KMT2B

1
1. scibot 30 May 2024
  
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  RRID:AB_306649
  
  DOI: 10.1016/j.parkreldis.2024.107018
  
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A chromatin code for limb segment identity in axolotl limb regeneration

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XIST and MUC1-C form an auto-regulatory pathway in driving cancer progression

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The histone lysine methyltransferase MLL1 regulates the activation and functional specialization of regulatory T cells

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The chromatin remodeler CHD4 sustains Ewing Sarcoma cell survival by controlling global chromatin architecture

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H2AK119ub1 differentially fine-tunes gene expression by modulating canonical PRC1- and H1-dependent chromatin compaction

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The sirtuin-associated human senescence program converges on the activation of placenta-specific gene PAPPA

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Deficiency of lncRNA MERRICAL abrogates macrophage chemotaxis and diabetes-associated atherosclerosis

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241-html.html

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Methionine secreted by tumor-associated pericytes supports cancer stem cells in clear cell renal carcinoma

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bvae029-html.html

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Locus-level L1 DNA methylation profiling reveals the epigenetic and transcriptional interplay between L1s and their integration sites

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Histone methylation readers MRG1/2 interact with PIF4 to promote thermomorphogenesis in Arabidopsis

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Spatiotemporal role of SETD2-H3K36me3 in murine pancreatic organogenesis

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Epigenetic regulator RNF20 underlies temporal hierarchy of gene expression to regulate postnatal cardiomyocyte polarization

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Discrete prefrontal neuronal circuits determine repeated stress-induced behavioral phenotypes in male mice

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XIST directly regulates X-linked and autosomal genes in naive human pluripotent cells

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Crosstalk between chromatin and Shavenbaby defines transcriptional output along the Drosophila intestinal stem cell lineage

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KDM5B predicts temozolomide-resistant subclones in glioblastoma

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Super-enhancers include classical enhancers and facilitators to fully activate gene expression

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ZNF397 Loss Triggers TET2-driven Epigenetic Rewiring, Lineage Plasticity, and AR-targeted Therapy Resistance in AR-dependent Cancers

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Genome-wide CRISPR activation screening in senescent cells reveals SOX5 as a driver and therapeutic target of rejuvenation

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Perturbations in 3D genome organization can promote acquired drug resistance

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Nuclear miR-150 enhances hepatic lipid accumulation by targeting RNA transcripts overlapping the PLIN2 promoter

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Stromal cells-specific retinoic acid determines parturition timing at single-cell and spatial-temporal resolution

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SMYD2 regulates vascular smooth muscle cell phenotypic switching and intimal hyperplasia via interaction with myocardin

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Aug 2023
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Loss of CtBP2 may be a mechanistic link between metabolic derangements and progressive impairment of pancreatic β cell function

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Histone variants shape chromatin states in Arabidopsis

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The default and directed pathways of hepatoblast differentiation involve distinct epigenomic mechanisms

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TONSOKU is required for the maintenance of repressive chromatin modifications in Arabidopsis

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Jun 2023
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Mutant IDH regulates glycogen metabolism from early cartilage development to malignant chondrosarcoma formation

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Mesenchymal stem cells overexpressing heme oxygenase-1 ameliorate lipopolysaccharide-induced acute lung injury in rats

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May 2023
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MYCOBACTERIUM MANRESENSIS INDUCES TRAINED IMMUNITY IN VITRO

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Chemical-induced epigenome resetting for regeneration program activation in human cells

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Mechanical pressure-induced dedifferentiation of myofibroblasts inhibits scarring via SMYD3/ITGBL1 signaling

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Co-transcriptional genome surveillance by HUSH is coupled to termination machinery

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Methionine consumption by cancer cells drives a progressive upregulation of PD-1 expression in CD4 T cells

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SMYD2 Regulates Vascular Smooth Muscle Cell Phenotypic Switching and Intimal Hyperplasia via Interaction with Myocardin

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ERCC6L2 mitigates replication stress and promotes centromere stability

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Cooperative super-enhancer inactivation caused by heterozygous loss of CREBBP and KMT2D skews B cell fate decisions and yields T cell-depleted lymphomas

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Mar 2023
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Proteasome Inhibitors Silence Oncogenes in Multiple Myeloma through Localized Histone Deacetylase 3 Stabilization and Chromatin Condensation

1
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TRIM28 represses renal cell carcinoma cell proliferation by inhibiting TFE3/KDM6A-regulated autophagy

1
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Feb 2023
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Transgenerational inheritance of acquired epigenetic signatures at CpG islands in mice

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Decorating chromatin for enhanced genome editing using CRISPR-Cas9

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  DOI: 10.1073/pnas.2204259119
  
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Jan 2023
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Principles of 3D chromosome folding and evolutionary genome reshuffling in mammals

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BRPF1 bridges H3K4me3 and H3K23ac in human ESCs and is essential to pluripotency

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Targeting Menin disrupts the KMT2A/B and polycomb balance to paradoxically activate bivalent genes

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  DOI: 10.1038/s41556-022-01056-x
  
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MOZ and Menin-MLL Complexes are Complementary Regulators of Chromatin Association and Transcriptional Output in Gastrointestinal Stromal Tumor

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Dec 2022
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Hypoxia induces transgenerational epigenetic inheritance of small RNAs

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KMT2D deficiency drives lung squamous cell carcinoma and hypersensitivity to RTK-RAS inhibition

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Mcm2 promotes stem cell differentiation via its ability to bind H3-H4

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Selective advantage of epigenetically disrupted cancer cells via phenotypic inertia

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  DOI: 10.1016/j.ccell.2022.10.002
  
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FBXO42 facilitates Notch signaling activation and global chromatin relaxation by promoting K63-linked polyubiquitination of RBPJ

1
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  DOI: 10.1126/sciadv.abq4831
  
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Loss of the Ash2l subunit of histone H3K4 methyltransferase complexes promotes chromatin compaction at promoters

1
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  DOI: 10.21203/rs.3.rs-1992778/v1
  
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FOXR2 is an epigenetically regulated pan-cancer oncogene that activates ETS transcriptional circuits

1
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  DOI: 10.1158/0008-5472.CAN-22-0671
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9437574/
Oct 2022
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FBXO42 facilitates Notch signaling activation and global chromatin relaxation by promoting K63-linked polyubiquitination of RBPJ

1
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  DOI: 10.1126/sciadv.abq4831
  
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Deficiency of peroxisomal NUDT7 stimulates de novo lipogenesis in hepatocytes

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  DOI: 10.1016/j.isci.2022.105135
  
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Small-molecule screening identifies Syk kinase inhibition and rutaecarpine as modulators of macrophage training and SARS-CoV-2 infection

1
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Sep 2022
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Histone H1 regulates non-coding RNA turnover on chromatin in a m6A-dependent manner

1
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Coronatine Enhances Chilling Tolerance of Tomato Plants by Inducing Chilling-Related Epigenetic Adaptations and Transcriptional Reprogramming

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  DOI: 10.3390/ijms231710049
  
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Methionine metabolism controls the B cell EBV epigenome and viral latency

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Repeat-based holocentromeres influence genome architecture and karyotype evolution

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Jul 2022
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Induction of senescence upon loss of the Ash2l core subunit of H3K4 methyltransferase complexes

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academic.oup.com/nar/advance-article/doi/10.1093/nar/gkac591/6640223
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Inhibition of DYRK1A, via histone modification, promotes cardiomyocyte cell cycle activation and cardiac repair after myocardial infarction

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Jun 2022
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cd-21-0646-html.html

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An oncogenic JMJD6-DGAT1 axis tunes the epigenetic regulation of lipid droplet formation in clear cell renal cell carcinoma

1
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Visualization of the dynamic interaction between nucleosomal histone H3K9 tri-methylation and HP1α chromodomain in living cells

1
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MacroH2As regulate enhancer-promoter contacts affecting enhancer activity and sensitivity to inflammatory cytokines

1
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  DOI: 10.1016/j.celrep.2022.110988
  
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Oncogenic ZMYND11-MBTD1 fusion protein anchors the NuA4/TIP60 histone acetyltransferase complex to the coding region of active genes

1
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May 2022
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Binary outcomes of enhancer activity underlie stable random monoallelic expression

1
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  DOI: 10.7554/eLife.74204
  
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Feedback from nuclear RNA on transcription promotes robust RNA concentration homeostasis in human cells

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Alcohol induced increases in sperm Histone H3 lysine 4 trimethylation correlate with increased placental CTCF occupancy and altered developmental programming

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Large-scale chromatin reorganization reactivates placenta-specific genes that drive cellular aging

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H3K4 methylation by SETD1A/BOD1L facilitates RIF1-dependent NHEJ

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Single-cell profiling of transcriptome and histone modifications with EpiDamID

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MUC1-C Dictates JUN and BAF-mediated Chromatin Remodeling at Enhancer Signatures in Cancer Stem Cells

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PRMT7 ablation stimulates anti-tumor immunity and sensitizes melanoma to immune checkpoint blockade

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MLL::AF9 degradation induces rapid changes in transcriptional elongation and subsequent loss of an active chromatin landscape

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Thymocytes trigger self-antigen-controlling pathways in immature medullary thymic epithelial stages

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The landscape of pioneer factor activity reveals the mechanisms of chromatin reprogramming and genome activation

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In vivo CRISPR screening identifies BAZ2 chromatin remodelers as druggable regulators of mammalian liver regeneration

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ASH1L haploinsufficiency results in autistic-like phenotypes in mice and links Eph receptor gene to autism spectrum disorder

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Opioid receptor signaling suppresses leukemia through both catalytic and non-catalytic functions of TET2

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SETDB1/NSD-dependent H3K9me3/H3K36me3 dual heterochromatin maintains gene expression profiles by bookmarking poised enhancers

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Single-cell-resolved dynamics of chromatin architecture delineate cell and regulatory states in zebrafish embryos

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Recruitment of MLL1 complex is essential for SETBP1 to induce myeloid transformation

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DOCK8-expressing T follicular helper cells newly generated beyond self-organized criticality cause systemic lupus erythematosus

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SUMOylation of linker histone H1 drives chromatin condensation and restriction of embryonic cell fate identity

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Sumoylation of the human histone H4 tail inhibits p300-mediated transcription by RNA polymerase II in cellular extracts

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Reprogramming of H3K9bhb at regulatory elements is a key feature of fasting in the small intestine

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An epigenetic mechanism underlying chromosome 17p deletion-driven tumorigenesis

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Sequence features of retrotransposons allow for epigenetic variability

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Cell division- and DNA replication-free reprogramming of somatic nuclei for embryonic transcription

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NRF1 association with AUTS2-Polycomb mediates specific gene activation in the brain

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Comparison of Histone H3K4me3 between IVF and ICSI Technologies and between Boy and Girl Offspring

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Parallel Reporter Assays Identify Altered Regulatory Role of rs684232 in Leading to Prostate Cancer Predisposition

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Multi-omic Profiling Reveals Dynamics of the Phased Progression of Pluripotency

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Deterministic Somatic Cell Reprogramming Involves Continuous Transcriptional Changes Governed by Myc and Epigenetic-Driven Modules

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KDM5 Histone Demethylase Activity Links Cellular Transcriptomic Heterogeneity to Therapeutic Resistance

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Contribution of synergism between PHF8 and HER2 signalling to breast cancer development and drug resistance

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Examining the Roles of H3K4 Methylation States with Systematically Characterized Antibodies

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A Pliable Mediator Acts as a Functional Rather Than an Architectural Bridge between Promoters and Enhancers

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Combinatorial Targeting by MicroRNAs Co-ordinates Post-transcriptional Control of EMT

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Multi-omic Profiling Reveals Dynamics of the Phased Progression of Pluripotency

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A map of human PRDM9 binding provides evidence for novel behaviors of PRDM9 and other zinc-finger proteins in meiosis.

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Retinoid X Receptor Activation Alters the Chromatin Landscape To Commit Mesenchymal Stem Cells to the Adipose Lineage

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Binary pan-cancer classes with distinct vulnerabilities defined by pro- or anti-cancer YAP/TEAD activity

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Reprogramming of bivalent chromatin states in NRAS mutant melanoma suggests PRC2 inhibition as a therapeutic strategy

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DDB1 binds histone reader BRWD3 to activate the transcriptional cascade in adipogenesis and promote onset of obesity

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A TORC1-histone axis regulates chromatin organisation and non-canonical induction of autophagy to ameliorate ageing

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Cystatin B-deficiency triggers ectopic histone H3 tail cleavage during neurogenesis

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Small RNAs are modified with N-glycans and displayed on the surface of living cells

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Methylation of histone H3 at lysine 37 by Set1 and Set2 prevents spurious DNA replication

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Opposing Effects of Cohesin and Transcription on CTCF Organization Revealed by Super-resolution Imaging

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PCAF-Mediated Histone Acetylation Promotes Replication Fork Degradation by MRE11 and EXO1 in BRCA-Deficient Cells

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Robust Hi-C Maps of Enhancer-Promoter Interactions Reveal the Function of Non-coding Genome in Neural Development and Diseases

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The Conserved Non-coding Sequences CNS6 and CNS9 Control Cytokine-Induced Rorc Transcription during T Helper 17 Cell Differentiation

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Folding Keratin Gene Clusters during Skin Regional Specification

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The chromatin-remodeling protein BAF60/SWP73A regulates the plant immune receptor NLRs

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MicroRNA-221 and -222 modulate intestinal inflammatory Th17 cell response as negative feedback regulators downstream of interleukin-23

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Distinct PRC2 subunits regulate maintenance and establishment of Polycomb repression during differentiation

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Serine metabolism antagonizes antiviral innate immunity by preventing ATP6V0d2-mediated YAP lysosomal degradation

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Biphasic Activation of WNT Signaling Facilitates the Derivation of Midbrain Dopamine Neurons from hESCs for Translational Use

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A unique histone 3 lysine 14 chromatin signature underlies tissue-specific gene regulation

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Chromatin Organization in Early Land Plants Reveals an Ancestral Association between H3K27me3, Transposons, and Constitutive Heterochromatin

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Bookmarking by Non-pioneer Transcription Factors during Liver Development Establishes Competence for Future Gene Activation

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Generation of PRMT6 homozygous knockout human embryonic stem cell lines

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Characterization of Metabolic Patterns in Mouse Oocytes during Meiotic Maturation

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G9a Promotes Breast Cancer Recurrence through Repression of a Pro-inflammatory Program

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Prior Hypoxia Exposure Enhances Murine Microglial Inflammatory Gene Expression in vitro Without Concomitant H3K4me3 Enrichment

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PRDM9 activity depends on HELLS and promotes local 5-hydroxymethylcytosine enrichment

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Epigenetic Mechanisms Contribute to Evolutionary Adaptation of Gene Network Activity under Environmental Selection

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Enhancer Reprogramming Confers Dependence on Glycolysis and IGF Signaling in KMT2D Mutant Melanoma

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The Gene-Regulatory Footprint of Aging Highlights Conserved Central Regulators

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DUX-miR-344-ZMYM2-Mediated Activation of MERVL LTRs Induces a Totipotent 2C-like State

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1. scibot 26 Sep 2020
  
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  DOI: 10.1016/j.stem.2020.01.004
  
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MEIOSIN Directs the Switch from Mitosis to Meiosis in Mammalian Germ Cells

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  DOI: 10.1016/j.devcel.2020.01.010
  
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Leukemogenic Chromatin Alterations Promote AML Leukemia Stem Cells via a KDM4C-ALKBH5-AXL Signaling Axis

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The histone modification reader ZCWPW1 links histone methylation to PRDM9-induced double-strand break repair

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  DOI: 10.7554/eLife.53459
  
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p53 Integrates Temporal WDR5 Inputs during Neuroectoderm and Mesoderm Differentiation of Mouse Embryonic Stem Cells

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KRAB-zinc finger protein gene expansion in response to active retrotransposons in the murine lineage

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1. scibot 23 Sep 2020
  
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  DOI: 10.7554/eLife.56337
  
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Regulated Proteolysis of MutSγ Controls Meiotic Crossing Over

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1. scibot 17 Sep 2020
  
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  DOI: 10.1016/j.molcel.2020.02.001
  
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MicroRNA-9 Fine-Tunes Dendritic Cell Function by Suppressing Negative Regulators in a Cell-Type-Specific Manner

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Inhibition of EZH2 Catalytic Activity Selectively Targets a Metastatic Subpopulation in Triple-Negative Breast Cancer

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Chromatin Organization in Early Land Plants Reveals an Ancestral Association between H3K27me3, Transposons, and Constitutive Heterochromatin

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cell.com/current-biology/abstract/S0960-9822(19)31610-0
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The Dm-Myb Oncoprotein Contributes to Insulator Function and Stabilizes Repressive H3K27me3 PcG Domains

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Bookmarking by Non-pioneer Transcription Factors during Liver Development Establishes Competence for Future Gene Activation

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cell.com/cell-reports/abstract/S2211-1247(20)30015-2
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Genome-wide R-loop Landscapes during Cell Differentiation and Reprogramming

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KMT2D Deficiency Impairs Super-Enhancers to Confer a Glycolytic Vulnerability in Lung Cancer

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Methionine Metabolism Shapes T Helper Cell Responses through Regulation of Epigenetic Reprogramming

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  DOI: 10.1016/j.cmet.2020.01.006
  
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Jan 2020
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The RNA Helicase DDX6 Controls Cellular Plasticity by Modulating P-Body Homeostasis

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1. scibot 13 Jan 2020
  
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  DOI: 10.1016/j.stem.2019.08.018
  
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