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72 Matching Annotations

Mar 2026
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Efficient amyloid-β degradation in Alzheimer’s disease using SPYTACs

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1. scibot 05 Mar 2026
  
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  DOI: 10.1016/j.cell.2026.01.034
  
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sciencedirect.com/science/article/pii/S0092867426001625
Jan 2026
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Synthetic cleavage-resistant TREM2 boosts macrophage efferocytosis to treat inflammatory diseases

1
1. scibot 30 Jan 2026
  
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  DOI: 10.1016/j.xcrm.2025.102580
  
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sciencedirect.com/science/article/pii/S2666379125006536
Nov 2025
www.cell.com www.cell.com

IL-1R1-positive dorsal raphe neurons drive self-imposed social withdrawal in sickness

1
1. scibot 29 Nov 2025
  
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  DOI: 10.1016/j.cell.2025.10.040
  
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cell.com/cell/fulltext/S0092-8674(25)01245-0
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

N-terminal oligomerization drives HDAC4 nuclear condensation and neurodevelopmental dysfunction in Drosophila

1
1. scibot 01 Nov 2025
  
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  DOI: 10.1098/rsob.250095
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12567083/
Sep 2025
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A pathological role of O-GlcNAcylation-driven TR11B production and function in lung adenocarcinoma

1
1. scibot 11 Sep 2025
  
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  DOI: 10.1016/j.devcel.2025.08.010
  
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sciencedirect.com/science/article/pii/S1534580725005301
Jul 2025
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TRIM24 directs replicative stress responses to maintain ALT telomeres via chromatin signaling

1
1. scibot 03 Jul 2025
  
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  DOI: 10.1016/j.molcel.2025.06.009
  
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sciencedirect.com/science/article/pii/S109727652500509X
Jun 2025
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The cell-surface shared proteome of astrocytes and neurons and the molecular foundations of their multicellular interactions

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1. scibot 11 Jun 2025
  
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  DOI: 10.1016/j.neuron.2025.05.019
  
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sciencedirect.com/science/article/pii/S0896627325003666
Feb 2025
52.53.155.43 52.53.155.43

1-s2.0-S2589004225002974-main-html.html

1
1. scibot 20 Feb 2025
  
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  DOI: 10.1016/j.isci.2025.112037
  
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52.53.155.43/e9c18890c8321e4e612915f5a218803f32bf4165/1-s2.0-S2589004225002974-main-html.html
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Membrane-tethered SCOTIN condensates elicit an endoplasmic reticulum stress response by sequestering luminal BiP

1
1. scibot 14 Feb 2025
  
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  DOI: 10.1016/j.celrep.2025.115297
  
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sciencedirect.com/science/article/pii/S2211124725000683
Dec 2024
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Two-ended recombination at a Flp-nickase-broken replication fork

1
1. scibot 05 Dec 2024
  
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  DOI: 10.1016/j.molcel.2024.11.006
  
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sciencedirect.com/science/article/pii/S1097276524009110
Jul 2024
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Dysregulation of FLVCR1a-dependent mitochondrial calcium handling in neural progenitors causes congenital hydrocephalus

1
1. scibot 17 Jul 2024
  
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  DOI: 10.1016/j.xcrm.2024.101647
  
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sciencedirect.com/science/article/pii/S2666379124003616
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Ankyrin2 is essential for neuronal morphogenesis and long-term courtship memory in Drosophila

1
1. scibot 14 Jul 2024
  
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  DOI: 10.1186/s13041-023-01026-w
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10186683/
Jun 2024
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EYA protein complex is required for Wntless retrograde trafficking from endosomes to Golgi

1
1. scibot 21 Jun 2024
  
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  DOI: 10.1016/j.devcel.2024.05.021
  
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sciencedirect.com/science/article/pii/S1534580724003393
May 2024
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The structure of the second CysD domain of MUC2 and role in mucin organization by transglutaminase-based cross-linking

1
1. scibot 10 May 2024
  
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  DOI: 10.1016/j.celrep.2024.114207
  
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sciencedirect.com/science/article/pii/S2211124724005357
Mar 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Regulation of hippocampal mossy fiber-CA3 synapse function by a Bcl11b/C1ql2/Nrxn3(25b+) pathway

1
1. scibot 19 Mar 2024
  
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  DOI: 10.7554/eLife.89854
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10942602/
Feb 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

A synthetic differentiation circuit in Escherichia coli for suppressing mutant takeover

1
1. scibot 06 Feb 2024
  
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  DOI: 10.1016/j.cell.2024.01.024
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10882425/
Jan 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Deciphering the roles of subcellular distribution and interactions involving the MEF2 binding region, the ankyrin repeat binding motif and the catalytic site of HDAC4 in Drosophila neuronal morphogenesis

1
1. scibot 19 Jan 2024
  
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  AB_307014
  
  DOI: 10.1186/s12915-023-01800-1
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10763444/
Dec 2023
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MeCP2 represses the activity of topoisomerase IIβ in long neuronal genes

1
1. scibot 17 Dec 2023
  
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  DOI: 10.1016/j.celrep.2023.113538
  
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sciencedirect.com/science/article/pii/S2211124723015504
Oct 2023
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JNK mediates cell death by promoting the ubiquitination of the apurinic/apyrimidinic endonuclease APE1

1
1. scibot 28 Oct 2023
  
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  AB_307014
  
  DOI: 10.1016/j.celrep.2023.113123
  
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sciencedirect.com/science/article/pii/S221112472301135X
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Intrinsically disordered region-mediated condensation of IFN-inducible SCOTIN/SHISA-5 inhibits ER-to-Golgi vesicle transport

1
1. scibot 13 Oct 2023
  
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  DOI: 10.1016/j.devcel.2023.08.030
  
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sciencedirect.com/science/article/pii/S1534580723004458
Sep 2023
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SMYD2 regulates vascular smooth muscle cell phenotypic switching and intimal hyperplasia via interaction with myocardin

1
1. scibot 07 Sep 2023
  
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  DOI: 10.1007/s00018-023-04883-9
  
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link.springer.com/article/10.1007/s00018-023-04883-9
Jul 2023
www.embopress.org www.embopress.org

Homotypic SCOTIN assemblies form ER-endosome membrane contacts and regulate endosome dynamics

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1. scibot 05 Jul 2023
  
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  DOI: 10.15252/embr.202256538
  
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embopress.org/doi/full/10.15252/embr.202256538
Jun 2023
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Polycomb repressive complex 2 binds and stabilizes NANOG to suppress differentiation-related genes to promote self-renewal

1
1. scibot 23 Jun 2023
  
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  DOI: 10.1016/j.isci.2023.107035
  
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sciencedirect.com/science/article/pii/S2589004223011124
May 2023
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

SMYD2 Regulates Vascular Smooth Muscle Cell Phenotypic Switching and Intimal Hyperplasia via Interaction with Myocardin

1
1. scibot 04 May 2023
  
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  DOI: 10.21203/rs.3.rs-2721176/v1
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10120764/
Apr 2023
52.53.155.43 52.53.155.43

MeCP2 Represses the Activity of Topoisomerase IIβ in Long Neuronal Genes

1
1. scibot 12 Apr 2023
  
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  DOI: 10.1101/2023.02.24.529960
  
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52.53.155.43/f9112145f5ddb849897c97bd39c4325cb2ff350e/2023.02.24.529960v1.full-html.html
Mar 2023
www.sciencedirect.com www.sciencedirect.com

Aspergillus fumigatus hijacks human p11 to redirect fungal-containing phagosomes to non-degradative pathway

1
1. scibot 10 Mar 2023
  
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  DOI: 10.1016/j.chom.2023.02.002
  
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sciencedirect.com/science/article/pii/S1931312823000720
Feb 2023
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Multiple ubiquitin E3 ligase genes antagonistically regulate chloroplast-associated protein degradation

1
1. scibot 23 Feb 2023
  
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  DOI: 10.1016/j.cub.2023.01.060
  
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sciencedirect.com/science/article/pii/S096098222300129X
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Single-cell transcriptome profiles of Drosophila fruitless-expressing neurons from both sexes

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1. scibot 04 Feb 2023
  
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  DOI: 10.7554/eLife.78511
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9891730/
Dec 2022
52.53.155.43 52.53.155.43

45_b22-00383-html.html

3
1. scibot 30 Dec 2022
  
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  DOI: 10.1016/j.jhazmat.2019.121526
  
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  DOI: 10.1016/j.jhazmat.2019.121526
  
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  DOI: 10.1016/j.jhazmat.2019.121526
  
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52.53.155.43/5a0cb9e99fb4bdcf59c1261ea8a643f76422aaa9/45_b22-00383 (2)-html.html
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Vibrio parahaemolyticus prey targeting requires autoproteolysis-triggered dimerization of the type VI secretion system effector RhsP

1
1. scibot 08 Dec 2022
  
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  DOI: 10.1016/j.celrep.2022.111732
  
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sciencedirect.com/science/article/pii/S2211124722016102
Oct 2022
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CasPlay provides a gRNA-barcoded CRISPR-based display platform for antibody repertoire profiling

1
1. scibot 20 Oct 2022
  
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  DOI: 10.1016/j.crmeth.2022.100318
  
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sciencedirect.com/science/article/pii/S2667237522002089
Jul 2022
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Ubiquitination and deubiquitination of 4E-T regulate neural progenitor cell maintenance and neurogenesis by controlling P-body formation

1
1. scibot 13 Jul 2022
  
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  DOI: 10.1016/j.celrep.2022.111070
  
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sciencedirect.com/science/article/pii/S2211124722008683
Jun 2022
onlinelibrary.wiley.com onlinelibrary.wiley.com

Protein interactome and cell-type expression analyses reveal that cytoplasmic FMR1-interacting protein 1 (CYFIP1), but not CYFIP2, associates with astrocytic focal adhesion

1
1. scibot 17 Jun 2022
  
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  DOI: 10.1111/jnc.15622
  
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onlinelibrary.wiley.com/doi/10.1111/jnc.15622
May 2022
link.springer.com link.springer.com

Cdk5-mediated JIP1 phosphorylation regulates axonal outgrowth through Notch1 inhibition

1
1. scibot 19 May 2022
  
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  DOI: 10.1186/s12915-022-01312-4
  
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link.springer.com/article/10.1186/s12915-022-01312-4
Nov 2021
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A novel role of KEAP1/PGAM5 complex: ROS sensor for inducing mitophagy

1
1. scibot 12 Nov 2021
  
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A sinusoidal transformation of the visual field is the basis for periodic maps in area V2

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The Hsp90 cochaperone TTT promotes cotranslational maturation of PIKKs prior to complex assembly

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Purification of GFP-tagged nuclei from frozen livers of INTACT mice for RNA- and ATAC-sequencing

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Dual film-like organelles enable spatial separation of orthogonal eukaryotic translation

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Maternally inherited piRNAs direct transient heterochromatin formation at active transposons during early Drosophila embryogenesis

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CRISPR-based peptide library display and programmable microarray self-assembly for rapid quantitative protein binding assays

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Axon morphogenesis and maintenance require an evolutionary conserved safeguard function of Wnk kinases antagonizing Sarm and Axed

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Glycosylphosphatidylinositol biosynthesis and remodeling are required for neural tube closure, heart development, and cranial neural crest cell survival

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Untitled document

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Pink1 regulates FKBP5 interaction with AKT/PHLPP and protects neurons from neurotoxin stress induced by MPP+

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Intrinsic Structural Features of the Human IRE1α Transmembrane Domain Sense Membrane Lipid Saturation

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Multiple pairs of allelic MLA immune receptor-powdery mildew AVRA effectors argue for a direct recognition mechanism

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Cholinergic neurons constitutively engage the ISR for dopamine modulation and skill learning in mice

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The Zika Virus Capsid Disrupts Corticogenesis by Suppressing Dicer Activity and miRNA Biogenesis

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The 10q26 Risk Haplotype of Age-Related Macular Degeneration Aggravates Subretinal Inflammation by Impairing Monocyte Elimination

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Endoglycan plays a role in axon guidance by modulating cell adhesion

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The leucine-rich repeats in allelic barley MLA immune receptors define specificity towards sequence-unrelated powdery mildew avirulence effectors with a predicted common RNase-like fold

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Promiscuous Binding of Microprotein Mozart1 to γ-Tubulin Complex Mediates Specific Subcellular Targeting to Control Microtubule Array Formation

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A terminal selector prevents a Hox transcriptional switch to safeguard motor neuron identity throughout life

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Induction of BDNF expression in layer II/III and layer V neurons of the motor cortex is essential for motor learning

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A WIZ/Cohesin/CTCF Complex Anchors DNA Loops to Define Gene Expression and Cell Identity

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A Requirement for Argonaute 4 in Mammalian Antiviral Defense

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Norrin mediates tumor-promoting and -suppressive effects in glioblastoma via Notch and WNT

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  DOI: 10.1172/JCI128994
  
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Phosphorylation of Ci/Gli by Fused Family Kinases Promotes Hedgehog Signaling

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Reconstituting Drosophila Centromere Identity in Human Cells

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Serotonergic Modulation of Aggression in Drosophila Involves GABAergic and Cholinergic Opposing Pathways

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Centralspindlin Recruits ALIX to the Midbody during Cytokinetic Abscission in Drosophila via a Mechanism Analogous to Virus Budding

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Intrinsic Structural Features of the Human IRE1α Transmembrane Domain Sense Membrane Lipid Saturation

1
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Multiple pairs of allelic MLA immune receptor-powdery mildew AVRA effectors argue for a direct recognition mechanism

1
1. scibot 12 Jan 2020
  
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ncbi.nlm.nih.gov/pmc/articles/PMC6414202/
Nov 2018
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Structural relationship between the putative hair cell mechanotransduction channel TMC1 and TMEM16 proteins

1
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ncbi.nlm.nih.gov/pmc/articles/PMC6067890/
Nov 2017
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Amyloid-like aggregation of provasopressin in diabetes insipidus and secretory granule sorting

2
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Registered report: Kinase-dead BRAF and oncogenic RAS cooperate to drive tumor progression through CRAF

1
1. scibot 08 Nov 2017
  
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  Rabbit α myc
  
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