Hypothesis

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Lactate-driven H3K18 lactylation promotes cisplatin resistance in bladder cancer via HNRNPF-Parkin mediated mitophagy

1
1. scibot 16 Jun 2026
  
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  RRID:AB_3076697
  
  DOI: 10.1016/j.drup.2026.101435
  
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sciencedirect.com/science/article/pii/S1368764626000865
Aug 2025
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A CD147-targeted small-molecule inhibitor potentiates gemcitabine efficacy by triggering ferroptosis in pancreatic ductal adenocarcinoma

1
1. scibot 20 Aug 2025
  
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  RRID:AB_3076697
  
  DOI: 10.1016/j.xcrm.2025.102292
  
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sciencedirect.com/science/article/pii/S2666379125003659
Jun 2025
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Lactate regulates cell differentiation of erythroid progenitor cells via histone lactylation modification

1
1. scibot 21 Jun 2025
  
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  RRID:AB_3076697
  
  DOI: 10.1016/j.isci.2025.112842
  
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sciencedirect.com/science/article/pii/S2589004225011034
Feb 2025
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Lactate shuttling links histone lactylation to adult hippocampal neurogenesis in mice

7
1. scibot 07 Feb 2025
  
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  RRID:AB_3076697
  
  DOI: 10.1016/j.devcel.2024.12.021
  
  Resource: (PTM BIO Cat# PTM-1414RM, RRID:AB_3076697)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_3076697
  
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  RRID:AB_3076697
2. scibot 06 Feb 2025
  
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  RRID:AB_3076697
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:AB_3076697
3. scibot 05 Feb 2025
  
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  RRID:AB_3076697
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:AB_3076697
4. scibot 04 Feb 2025
  
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  RRID:AB_3076697
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:AB_3076697
5. scibot 03 Feb 2025
  
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  RRID:AB_3076697
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:AB_3076697
6. scibot 02 Feb 2025
  
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  RRID:AB_3076697
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:AB_3076697
7. scibot 01 Feb 2025
  
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  RRID:AB_3076697
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:AB_3076697
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URL

sciencedirect.com/science/article/pii/S1534580724007603
Jan 2025
www.sciencedirect.com www.sciencedirect.com

Lactate shuttling links histone lactylation to adult hippocampal neurogenesis in mice

25
1. scibot 31 Jan 2025
  
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  RRID:AB_3076697
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:AB_3076697
2. scibot 30 Jan 2025
  
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  RRID:AB_3076697
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:AB_3076697
3. scibot 29 Jan 2025
  
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  RRID:AB_3076697
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:AB_3076697
4. scibot 28 Jan 2025
  
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  RRID:AB_3076697
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:AB_3076697
5. scibot 27 Jan 2025
  
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  RRID:AB_3076697
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:AB_3076697
6. scibot 26 Jan 2025
  
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  RRID:AB_3076697
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:AB_3076697
7. scibot 25 Jan 2025
  
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  RRID:AB_3076697
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:AB_3076697
8. scibot 24 Jan 2025
  
  in Public
  
  RRID:AB_3076697
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:AB_3076697
9. scibot 23 Jan 2025
  
  in Public
  
  RRID:AB_3076697
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:AB_3076697
10. scibot 22 Jan 2025
  
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  RRID:AB_3076697
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:AB_3076697
11. scibot 21 Jan 2025
  
  in Public
  
  RRID:AB_3076697
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:AB_3076697
12. scibot 20 Jan 2025
  
  in Public
  
  RRID:AB_3076697
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:AB_3076697
13. scibot 19 Jan 2025
  
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  RRID:AB_3076697
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:AB_3076697
14. scibot 18 Jan 2025
  
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  RRID:AB_3076697
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:AB_3076697
15. scibot 17 Jan 2025
  
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  RRID:AB_3076697
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:AB_3076697
16. scibot 16 Jan 2025
  
  in Public
  
  RRID:AB_3076697
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:AB_3076697
17. scibot 15 Jan 2025
  
  in Public
  
  RRID:AB_3076697
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:AB_3076697
18. scibot 14 Jan 2025
  
  in Public
  
  RRID:AB_3076697
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:AB_3076697
19. scibot 13 Jan 2025
  
  in Public
  
  RRID:AB_3076697
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:AB_3076697
20. scibot 12 Jan 2025
  
  in Public
  
  RRID:AB_3076697
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:AB_3076697
21. scibot 11 Jan 2025
  
  in Public
  
  RRID:AB_3076697
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:AB_3076697
22. scibot 10 Jan 2025
  
  in Public
  
  RRID:AB_3076697
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:AB_3076697
23. scibot 09 Jan 2025
  
  in Public
  
  RRID:AB_3076697
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:AB_3076697
24. scibot 08 Jan 2025
  
  in Public
  
  RRID:AB_3076697
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:AB_3076697
25. scibot 07 Jan 2025
  
  in Public
  
  RRID:AB_3076697
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:AB_3076697
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URL

sciencedirect.com/science/article/pii/S1534580724007603
Nov 2024
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ACSS2 acts as a lactyl-CoA synthetase and couples KAT2A to function as a lactyltransferase for histone lactylation and tumor immune evasion

1
1. scibot 24 Nov 2024
  
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  RRID:AB_3076697
  
  DOI: 10.1016/j.cmet.2024.10.015
  
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sciencedirect.com/science/article/pii/S155041312400411X
Oct 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Sirtuin 1/sirtuin 3 are robust lysine delactylases and sirtuin 1-mediated delactylation regulates glycolysis

1
1. scibot 05 Oct 2024
  
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  RRID:AB_3076697
  
  DOI: 10.1016/j.isci.2024.110911
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11440250/
May 2024
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Macrophage MCT4 inhibition activates reparative genes and protects from atherosclerosis by histone H3 lysine 18 lactylation

1
1. scibot 14 May 2024
  
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  RRID:AB_3076697
  
  DOI: 10.1016/j.celrep.2024.114180
  
  Resource: (PTM BIO Cat# PTM-1414RM, RRID:AB_3076697)
  
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sciencedirect.com/science/article/pii/S2211124724005084
Jan 2024
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Augmentation of scleral glycolysis promotes myopia through histone lactylation

1
1. scibot 19 Jan 2024
  
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  RRID:AB_3076697
  
  DOI: 10.1016/j.cmet.2023.12.023
  
  Resource: AB_3076697
  
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sciencedirect.com/science/article/pii/S1550413123004746

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