19 Matching Annotations
  1. Jun 2026
  2. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    High-throughput screening approach identifies substrate-selective Hsp104 variants that counter amyloid seeding with diminished off-target effects
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    pmc.ncbi.nlm.nih.gov/articles/PMC13238597/
  3. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    FET Fusion Oncoproteins Disrupt Physiologic DNA Repair and Create a Targetable Opportunity for ATR Inhibitor Therapy
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    pmc.ncbi.nlm.nih.gov/articles/PMC13223543/
  4. Jul 2025
  5. 52.53.155.43 52.53.155.43
    watanabe-et-al-als-associated-rna-binding-proteins-promote-unc13a-transcription-through-rest-downregulation-html.html
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    52.53.155.43/42423fb21c90eb6b2282f89153f3787d8f44c56d/watanabe-et-al-als-associated-rna-binding-proteins-promote-unc13a-transcription-through-rest-downregulation-html.html
  6. Mar 2025
  7. www.sciencedirect.com www.sciencedirect.com
    TDP-43 seeding induces cytoplasmic aggregation heterogeneity and nuclear loss of function of TDP-43
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    sciencedirect.com/science/article/pii/S089662732500176X
  8. Dec 2024
  9. www.sciencedirect.com www.sciencedirect.com
    Design principles to tailor Hsp104 therapeutics
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    sciencedirect.com/science/article/pii/S2211124724013561
  10. Jul 2024
  11. www.sciencedirect.com www.sciencedirect.com
    Blending and separating dynamics of RNA-binding proteins develop architectural splicing networks spreading throughout the nucleus
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    sciencedirect.com/science/article/pii/S1097276524005446
  12. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Multivalent GU-rich oligonucleotides sequester TDP-43 in the nucleus by inducing high molecular weight RNP complexes
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    ncbi.nlm.nih.gov/pmc/articles/PMC11233918/
  13. Mar 2024
  14. www.sciencedirect.com www.sciencedirect.com
    Transcription elongation defects link oncogenic SF3B1 mutations to targetable alterations in chromatin landscape
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    sciencedirect.com/science/article/pii/S1097276524001758
  15. Aug 2023
  16. www.sciencedirect.com www.sciencedirect.com
    Tuning Hsp104 specificity to selectively detoxify α-synuclein
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    sciencedirect.com/science/article/abs/pii/S1097276523006044
  17. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    FUS regulates RAN translation through modulating the G-quadruplex structure of GGGGCC repeat RNA in C9orf72-linked ALS/FTD
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    ncbi.nlm.nih.gov/pmc/articles/PMC10393046/
  18. Dec 2022
  19. www.sciencedirect.com www.sciencedirect.com
    A minimal construct of nuclear-import receptor Karyopherin-β2 defines the regions critical for chaperone and disaggregation activity
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    sciencedirect.com/science/article/pii/S0021925822012492
  20. Mar 2022
  21. www.sciencedirect.com www.sciencedirect.com
    Therapeutic modulation of GSTO activity rescues FUS-associated neurotoxicity via deglutathionylation in ALS disease models
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    sciencedirect.com/science/article/pii/S1534580722001241
  22. Aug 2021
  23. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Untitled document
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    ncbi.nlm.nih.gov/pmc/articles/PMC6277851/
  24. Jul 2021
  25. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Synaptic FUS Localization During Motoneuron Development and Its Accumulation in Human ALS Synapses
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    ncbi.nlm.nih.gov/pmc/articles/PMC6582137/
  26. Jan 2020
  27. www.sciencedirect.com www.sciencedirect.com
    Mining Disaggregase Sequence Space to Safely Counter TDP-43, FUS, and α-Synuclein Proteotoxicity
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    sciencedirect.com/science/article/pii/S2211124719309738
  28. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Chronic optogenetic induction of stress granules is cytotoxic and reveals the evolution of ALS-FTD pathology
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    ncbi.nlm.nih.gov/pmc/articles/PMC6426440/
  29. Nov 2018
  30. www.sciencedirect.com www.sciencedirect.com
    Untitled document
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    sciencedirect.com/science/article/pii/S0896627318308468
  31. academic.oup.com academic.oup.com
    FUS-induced neurotoxicity in Drosophila is prevented by downregulating nucleocytoplasmic transport proteinsHuman Molecular Genetics, 2018, Vol. 00, No. 0Human Molecular Genetics, 2018, Vol. 00, No. 0
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    academic.oup.com/hmg/advance-article/doi/10.1093/hmg/ddy303/5078635
  32. www.sciencedirect.com www.sciencedirect.com
    Nuclear-Import Receptors Reverse Aberrant Phase Transitions of RNA-Binding Proteins with Prion-like Domains
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    sciencedirect.com/science/article/pii/S0092867418302824