5 Matching Annotations
  1. Oct 2025
  2. www.biorxiv.org www.biorxiv.org
    Metabolic Alterations driven by PFKFB3 upregulation confer Resistance to Trastuzumab in HER2-Positive Breast Cancer
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    biorxiv.org/content/10.1101/2025.10.09.681343v1
  3. Sep 2025
  4. faseb.onlinelibrary.wiley.com faseb.onlinelibrary.wiley.com
    Deficiency of Microglial Hv1 Protects Against Lipopolysaccharide-Induced Neuroinflammation via the NF-κB Signaling Pathway and HIF1α-Mediated Metabolic Reprogramming
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    faseb.onlinelibrary.wiley.com/doi/10.1096/fj.202402271RRR
  5. Jul 2025
  6. www.sciencedirect.com www.sciencedirect.com
    PFKFB3 activates CAD to enhance de novo pyrimidine synthesis for cell growth
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    sciencedirect.com/science/article/pii/S2211124725008423
  7. Jun 2025
  8. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    CRISPR/Cas9 Screening Highlights PFKFB3 Gene as a Major Contributor to 5-Fluorouracil Resistance in Esophageal Cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC12109790/
  9. Mar 2025
  10. www.cell.com www.cell.com
    Realigned transsulfuration drives BRAF-V600E-targeted therapy resistance in melanoma
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    cell.com/cell-metabolism/fulltext/S1550-4131(25)00021-X