85 Matching Annotations
  1. Apr 2024
  2. www.sciencedirect.com www.sciencedirect.com
    Prophylactic treatment with the c-Abl inhibitor, neurotinib, diminishes neuronal damage and the convulsive state in pilocarpine-induced mice
    1
    1. scibot 24 Apr 2024
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    sciencedirect.com/science/article/pii/S2211124724004728
  3. Mar 2024
  4. rupress.org rupress.org
    The Cby3/ciBAR1 complex positions the annulus along the sperm flagellum during spermiogenesis
    1
    1. scibot 21 Mar 2024
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      DOI: 10.1083/jcb.202307147

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    rupress.org/jcb/article/223/3/e202307147/276492/The-Cby3-ciBAR1-complex-positions-the-annulus
  5. Aug 2023
  6. 52.53.155.43 52.53.155.43
    PIIS2589004223016838-html.html
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    1. scibot 17 Aug 2023
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    52.53.155.43/0595295f970fa120203481e8752220bf0b62043f/PIIS2589004223016838-html.html
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    ArfGAP1 regulates the endosomal sorting of guidance receptors to promote directed collective cell migration in vivo
    1
    1. scibot 10 Aug 2023
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    sciencedirect.com/science/article/pii/S2589004223015444
  8. Jul 2023
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    GSDMA3 deficiency reprograms cellular metabolism and modulates BCR signaling in murine B cells
    1
    1. scibot 21 Jul 2023
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    sciencedirect.com/science/article/pii/S2589004223014189
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    Activation of autophagy depends on Atg1/Ulk1-mediated phosphorylation and inhibition of the Hsp90 chaperone machinery
    1
    1. scibot 15 Jul 2023
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    sciencedirect.com/science/article/pii/S2211124723008185
  11. May 2023
  12. www.sciencedirect.com www.sciencedirect.com
    CKB regulates BCAR1 phosphorylation to facilitate DNA damage repair
    1
    1. scibot 13 May 2023
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      DOI: 10.1016/j.isci.2023.106684

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    sciencedirect.com/science/article/pii/S2589004223007617
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    Tyrosine kinases compete for growth hormone receptor binding and regulate receptor mobility and degradation
    1
    1. scibot 10 May 2023
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    sciencedirect.com/science/article/pii/S2211124723005016
  14. Apr 2023
  15. www.sciencedirect.com www.sciencedirect.com
    Differential Hsp90-dependent gene expression is strain-specific and common among yeast strains
    1
    1. scibot 27 Apr 2023
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      DOI: 10.1016/j.isci.2023.106635

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    sciencedirect.com/science/article/pii/S2589004223007125
  16. Jan 2023
  17. www.sciencedirect.com www.sciencedirect.com
    Evolutionarily conserved regulators of tau identify targets for new therapies
    1
    1. scibot 07 Jan 2023
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      DOI: 10.1016/j.neuron.2022.12.012

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    sciencedirect.com/science/article/pii/S0896627322010856
  18. Aug 2022
  19. www.sciencedirect.com www.sciencedirect.com
    ABL kinases regulate translation in HER2+ cells through Y-box-binding protein 1 to facilitate colonization of the brain
    1
    1. scibot 31 Aug 2022
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    sciencedirect.com/science/article/pii/S2211124722010865
  20. Jul 2022
  21. www.sciencedirect.com www.sciencedirect.com
    A specialized Hsp90 co-chaperone network regulates steroid hormone receptor response to ligand
    1
    1. scibot 13 Jul 2022
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      DOI: 10.1016/j.celrep.2022.111039

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    sciencedirect.com/science/article/pii/S2211124722008336
  22. www.sciencedirect.com www.sciencedirect.com
    EPH receptor tyrosine kinases phosphorylate the PAR-3 scaffold protein to modulate downstream signaling networks
    1
    1. scibot 06 Jul 2022
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      DOI: 10.1016/j.celrep.2022.111031

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    sciencedirect.com/science/article/pii/S2211124722008257
  23. May 2022
  24. aacrjournals.org aacrjournals.org
    Irreversible FLT3 Inhibitor FF-10101 Is Active Against a Diversity of FLT3 Inhibitor Resistance Mechanisms
    1
    1. scibot 14 May 2022
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      DOI: 10.1158/1535-7163.MCT-21-0317

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    aacrjournals.org/mct/article/21/5/844/694774/The-Irreversible-FLT3-Inhibitor-FF-10101-Is-Active
  25. Apr 2022
  26. www.sciencedirect.com www.sciencedirect.com
    Betacellulin promotes tumor development and EGFR mutant lung cancer growth by stimulating the EGFR pathway and suppressing apoptosis
    1
    1. scibot 26 Apr 2022
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      DOI: 10.1016/j.isci.2022.104211

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    sciencedirect.com/science/article/pii/S2589004222004813
  27. Feb 2022
  28. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Dual Sensing of Physiologic pH and Calcium by EFCAB9 Regulates Sperm Motility
    1
    1. scibot 04 Feb 2022
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      DOI: 10.1016/j.cell.2019.03.047

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    ncbi.nlm.nih.gov/pmc/articles/PMC8808721/
  29. Jan 2022
  30. www.sciencedirect.com www.sciencedirect.com
    ASH1L haploinsufficiency results in autistic-like phenotypes in mice and links Eph receptor gene to autism spectrum disorder
    1
    1. scibot 29 Jan 2022
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      DOI: 10.1016/j.neuron.2021.12.035

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    sciencedirect.com/science/article/pii/S0896627321010904
  31. www.sciencedirect.com www.sciencedirect.com
    Citrulline depletion by ASS1 is required for proinflammatory macrophage activation and immune responses
    1
    1. scibot 11 Jan 2022
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      DOI: 10.1016/j.molcel.2021.12.006

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    sciencedirect.com/science/article/pii/S1097276521010686
  32. www.sciencedirect.com www.sciencedirect.com
    C2cd6-encoded CatSperτ targets sperm calcium channel to Ca2+ signaling domains in the flagellar membrane
    1
    1. scibot 08 Jan 2022
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      DOI: 10.1016/j.celrep.2021.110226

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    sciencedirect.com/science/article/pii/S2211124721017307
  33. Nov 2021
  34. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    p190RhoGAP Filters Competing Signals to Resolve Axon Guidance Conflicts
    1
    1. scibot 29 Nov 2021
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      DOI: 10.1016/j.neuron.2019.02.034

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    ncbi.nlm.nih.gov/pmc/articles/PMC8608148/
  35. academic.oup.com academic.oup.com
    Reassessment of the proteomic composition and function of extracellular vesicles in the seminal plasma
    1
    1. scibot 25 Nov 2021
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      DOI: 10.1210/endocr/bqab214

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    academic.oup.com/endo/article/163/1/bqab214/6396829
  36. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    NHE6 depletion corrects ApoE4-mediated synaptic impairments and reduces amyloid plaque load
    1
    1. scibot 05 Nov 2021
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      DOI: 10.7554/eLife.72034

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    ncbi.nlm.nih.gov/pmc/articles/PMC8547963/
  37. Oct 2021
  38. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Secretory mouse quiescin sulfhydryl oxidase 1 aggregates defected human and mouse spermatozoa in vitro and in vivo
    1
    1. scibot 21 Oct 2021
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      DOI: 10.1016/j.isci.2021.103167

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    ncbi.nlm.nih.gov/pmc/articles/PMC8506963/
  39. www.sciencedirect.com www.sciencedirect.com
    Tyrosine Phosphorylation of DEPTOR Functions as a Molecular Switch to Activate mTOR Signaling
    1
    1. scibot 14 Oct 2021
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      DOI: 10.1016/j.jbc.2021.101291

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    sciencedirect.com/science/article/pii/S0021925821010966
  40. Aug 2021
  41. www.sciencedirect.com www.sciencedirect.com
    NAD+ supplement potentiates tumor-killing function by rescuing defective TUB-mediated NAMPT transcription in tumor-infiltrated T cells
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    1. scibot 15 Aug 2021
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    sciencedirect.com/science/article/pii/S2211124721009463
  42. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Protein Tyrosine Phosphatase δ mediates the Sema3A-induced cortical basal dendritic arborization through the activation of Fyn tyrosine kinase
    1
    1. scibot 14 Aug 2021
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      DOI: 10.1523/JNEUROSCI.2519-16.2017

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    ncbi.nlm.nih.gov/pmc/articles/PMC6705738/
  43. academic.oup.com academic.oup.com
    USP8 deubiquitinates the leptin receptor and is necessary for leptin-mediated synapse formation
    1
    1. scibot 14 Aug 2021
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      DOI: 10.1210/en.2019-00107

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    academic.oup.com/endo/article/160/8/1982/5518337
  44. academic.oup.com academic.oup.com
    Untitled document
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    1. scibot 08 Aug 2021
      AB_309678

      DOI: 10.1210/en.2017-00469

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    academic.oup.com/endo/article/158/10/3235/4058081
  45. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Untitled document
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    1. scibot 07 Aug 2021
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      DOI: 10.7554/eLife.37776

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    ncbi.nlm.nih.gov/pmc/articles/PMC6239434/
  46. www.sciencedirect.com www.sciencedirect.com
    Defining Human Tyrosine Kinase Phosphorylation Networks Using Yeast as an In Vivo Model Substrate
    1
    1. scibot 06 Aug 2021
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      DOI: 10.1016/j.cels.2017.08.001

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    sciencedirect.com/science/article/pii/S2405471217303344
  47. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Untitled document
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      DOI: 10.7554/eLife.40048

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    ncbi.nlm.nih.gov/pmc/articles/PMC6261251/
  48. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    KLK3/PSA and cathepsin D activate VEGF-C and VEGF-D
    1
    1. scibot 01 Aug 2021
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      DOI: 10.7554/eLife.44478

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    ncbi.nlm.nih.gov/pmc/articles/PMC6588350/
  49. Jul 2021
  50. www.sciencedirect.com www.sciencedirect.com
    ERBB3 overexpression due to miR-205 inactivation confers sensitivity to FGF, metabolic activation, and liability to ERBB3 targeting in glioblastoma
    1
    1. scibot 31 Jul 2021
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      DOI: 10.1016/j.celrep.2021.109455

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    sciencedirect.com/science/article/pii/S221112472100872X
  51. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Distal Dendritic Enrichment of HCN1 Channels in Hippocampal CA1 Is Promoted by Estrogen, but Does Not Require Reelin
    1
    1. scibot 30 Jul 2021
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      DOI: 10.1523/ENEURO.0258-18.2018

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    ncbi.nlm.nih.gov/pmc/articles/PMC6220572/
  52. www.frontiersin.org www.frontiersin.org
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      DOI: 10.3389/fphar.2017.00365

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    frontiersin.org/article/10.3389/fphar.2017.00365/full
  53. www.sciencedirect.com www.sciencedirect.com
    Allosteric activation of T cell antigen receptor signaling by quaternary structure relaxation
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    1. scibot 14 Jul 2021
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      DOI: 10.1016/j.celrep.2021.109375

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    sciencedirect.com/science/article/pii/S2211124721007737
  54. Jun 2021
  55. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Sperm Behavior and Response to Melatonin under Capacitating Conditions in Three Sheep Breeds Subject to the Equatorial Photoperiod
    1
    1. scibot 29 Jun 2021
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      DOI: 10.3390/ani11061828

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    ncbi.nlm.nih.gov/pmc/articles/PMC8235450/
  56. May 2021
  57. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Phosphorylation of Collapsin Response Mediator Protein 1 (CRMP1) at Tyrosine 504 residue regulates Semaphorin 3A-induced cortical dendritic growth
    1
    1. scibot 20 May 2021
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      DOI: 10.1111/jnc.15304

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    onlinelibrary.wiley.com/doi/10.1111/jnc.15304
  58. www.sciencedirect.com www.sciencedirect.com
    Helicobacter pylori CagA elicits BRCAness to induce genome instability that may underlie bacterial gastric carcinogenesis
    1
    1. scibot 14 May 2021
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      DOI: 10.1016/j.chom.2021.04.006

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    sciencedirect.com/science/article/pii/S1931312821001827
  59. mcr.aacrjournals.org mcr.aacrjournals.org
    Heparan Sulfate Synthesized by Ext1 Regulates Receptor Tyrosine Kinase Signaling and Promotes Resistance to EGFR Inhibitors in GBM
    1
    1. scibot 10 May 2021
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      DOI: 10.1158/1541-7786.MCR-20-0420

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    mcr.aacrjournals.org/content/19/1/150
  60. www.sciencedirect.com www.sciencedirect.com
    Integrin-Linked Kinase Mediates Therapeutic Resistance of Quiescent CML Stem Cells to Tyrosine Kinase Inhibitors
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    Structural Insights into Pseudokinase Domains of Receptor Tyrosine Kinases
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  62. Apr 2021
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    Reduction of Liver Metastasis Stiffness Improves Response to Bevacizumab in Metastatic Colorectal Cancer
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    Underlying molecular mechanism in the modulation of the ram sperm acrosome reaction by progesterone and 17β-estradiol
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    Primary cilia-dependent lipid raft/caveolin dynamics regulate adipogenesis
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  67. Jan 2021
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    The ER-embedded UBE2J1/RNF26 ubiquitylation complex exerts spatiotemporal control over the endolysosomal pathway
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    Critical role of Syk-dependent STAT1 activation in innate antiviral immunity
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  70. Dec 2020
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    3D in situ imaging of the female reproductive tract reveals molecular signatures of fertilizing spermatozoa in mice
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  72. Nov 2020
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    An Acquired and Endogenous Glycocalyx Forms a Bidirectional “Don’t Eat” and “Don’t Eat Me” Barrier to Phagocytosis
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    Reelin-Nrp1 Interaction Regulates Neocortical Dendrite Development in a Context-Specific Manner
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  75. Oct 2020
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    Identification of Interleukin1β as an Amplifier of Interferon alpha-induced Antiviral Responses
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    The Secreted Glycoprotein Reelin Suppresses the Proliferation and Regulates the Distribution of Oligodendrocyte Progenitor Cells in the Embryonic Neocortex
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  78. Sep 2020
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    Roles of Pyk2 in signal transduction after gonadotropin‐releasing hormone receptor stimulation
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    Involvement of progesterone and estrogen receptors in the ram sperm acrosome reaction
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    A Bartonella Effector Acts as Signaling Hub for Intrinsic STAT3 Activation to Trigger Anti-inflammatory Responses
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  82. Jan 2020
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    TAM Kinases Promote Necroptosis by Regulating Oligomerization of MLKL
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    Heparan sulfates are critical regulators of the inhibitory megakaryocyte-platelet receptor G6b-B
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    Quantitative Interactomics in Primary T Cells Provides a Rationale for Concomitant PD-1 and BTLA Coinhibitor Blockade in Cancer Immunotherapy
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    Timely Inhibitory Circuit Formation Controlled by Abl1 Regulates Innate Olfactory Behaviors in Mouse
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    A TAZ-AXL-ABL2 Feed-Forward Signaling Axis Promotes Lung Adenocarcinoma Brain Metastasis
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    Molecularly Distinct Clathrin-Coated Pits Differentially Impact EGFR Fate and Signaling
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    Extracellular vesicles from oviductal isthmus and ampulla stimulate the induced acrosome reaction and signaling events associated with capacitation in bovine spermatozoa
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    Loss of tau and Fyn reduces compensatory effects of MAP2 for tau and reveals a Fyn‐independent effect of tau on calcium
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    Oncogenic Mutations Rewire Signaling Pathways by Switching Protein Recruitment to Phosphotyrosine Sites
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    3D Cellular Architecture Modulates Tyrosine Kinase Activity, Thereby Switching CD95-Mediated Apoptosis to Survival
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  93. pubs.acs.org pubs.acs.org
    A novel small molecule supports the survival of cultured dopamine neurons and may restore the dopaminergic innervation of the brain in the MPTP mouse model of Parkinson's disease
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      DOI: 10.1021/acschemneuro.9b00396

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    Time-Variant SRC Kinase Activation Determines Endothelial Permeability Response
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  100. Nov 2018
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    Loss of PRMT5 Promotes PDGFRα Degradation during Oligodendrocyte Differentiation and Myelination
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    Mechanism of Allosteric Coupling into and through the Plasma Membrane by EGFR
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    Angiogenin/Ribonuclease 5 Is an EGFR Ligand and a Serum Biomarker for Erlotinib Sensitivity in Pancreatic Cancer
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  105. Nov 2017
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    Subdomain 2, Not the Transmembrane Domain, Determines the Dimerization Partner of Growth Hormone Receptor and Prolactin Receptor
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    The Plasticity of the Hsp90 Co-chaperone System
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  109. europepmc.org europepmc.org
    A Novel Small Molecule GDNF Receptor RET Agonist, BT13, Promotes Neurite Growth from Sensory Neurons in Vitro and Attenuates Experimental Neuropathy in the Rat.
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    A Phosphosite within the SH2 Domain of Lck Regulates Its Activation by CD45
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      SciCrunch record: RRID:AB_309678

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      RRID:AB_309678 RRIDCUR:Validated
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    sciencedirect.com/science/article/pii/S1097276517304586
  111. www.sciencedirect.com www.sciencedirect.com
    Amplification of F-Actin Disassembly and Cellular Repulsion by Growth Factor Signaling
    1
    1. scibot 08 Nov 2017
      AB_309678

      Curator: @chewbeccax

      Resource used:

      (Millipore Cat# 05-321, RRID:AB_309678)

      SciCrunch record: RRID:AB_309678

      Alternate resolvers: SciCrunch xml N2T identifiers.org

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      RRID:AB_309678 RRIDCUR:Validated
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    sciencedirect.com/science/article/pii/S153458071730463X
  112. www.sciencedirect.com www.sciencedirect.com
    A Tunable Brake for HECT Ubiquitin Ligases
    1
    1. scibot 08 Nov 2017
      AB_309678

      Curator: @chewbeccax

      Resource used:

      (Millipore Cat# 05-321, RRID:AB_309678)

      SciCrunch record: RRID:AB_309678

      Alternate resolvers: SciCrunch xml N2T identifiers.org

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      RRID:AB_309678 RRIDCUR:Validated
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    sciencedirect.com/science/article/pii/S1097276517302307
  113. www.sciencedirect.com www.sciencedirect.com
    Distinct Requirements for FGFR1 and FGFR2 in Primitive Endoderm Development and Exit from Pluripotency
    1
    1. scibot 08 Nov 2017
      AB_309678

      Curator: @Zeljana_Babic

      Resource used:

      (Millipore Cat# 05-321, RRID:AB_309678)

      SciCrunch record: RRID:AB_309678

      Alternate resolvers: SciCrunch xml N2T identifiers.org

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      RRID:AB_309678 RRIDCUR:Validated
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    sciencedirect.com/science/article/pii/S1534580717303866
  114. www.sciencedirect.com www.sciencedirect.com
    Phosphorylation of β-Tubulin by the Down Syndrome Kinase, Minibrain/DYRK1a, Regulates Microtubule Dynamics and Dendrite Morphogenesis
    1
    1. scibot 08 Nov 2017
      AB_309678

      Curator: @gabimpine

      Resource used:

      (Millipore Cat# 05-321, RRID:AB_309678)

      SciCrunch record: RRID:AB_309678

      Alternate resolvers: SciCrunch xml N2T identifiers.org

      What is this?

      RRID:AB_309678 RRIDCUR:Validated
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    sciencedirect.com/science/article/pii/S0896627316300186