300 Matching Annotations
  1. Apr 2024
  2. aacrjournals.org aacrjournals.org
    Adipose triglyceride lipase is a therapeutic target in advanced prostate cancer that promotes metabolic plasticity
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    1. scibot 19 Apr 2024
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    aacrjournals.org/cancerres/article/84/5/703/734936/Adipose-Triglyceride-Lipase-Is-a-Therapeutic
  3. www.sciencedirect.com www.sciencedirect.com
    Dyrk1a is required for craniofacial development in Xenopus laevis.
    1
    1. scibot 16 Apr 2024
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    sciencedirect.com/science/article/pii/S001216062400099X
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    Duox activation in Drosophila Malpighian tubules stimulates intestinal epithelial renewal through a countercurrent flow
    1
    1. scibot 16 Apr 2024
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    sciencedirect.com/science/article/pii/S2211124724004376
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    Y chromosome damage underlies testicular abnormalities in ATR-X syndrome
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    1. scibot 11 Apr 2024
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    sciencedirect.com/science/article/pii/S2589004224008514
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    NIBR-LTSi is a selective LATS kinase inhibitor activating YAP signaling and expanding tissue stem cells in vitro and in vivo
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    1. scibot 05 Apr 2024
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      DOI: 10.1016/j.stem.2024.03.003

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    sciencedirect.com/science/article/pii/S1934590924000845
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    A senescence restriction point acting on chromatin integrates oncogenic signals
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    1. scibot 04 Apr 2024
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    sciencedirect.com/science/article/pii/S2211124724003723
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    Vangl-dependent mesenchymal thinning shapes the distal lung during murine sacculation
    1
    1. scibot 04 Apr 2024
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    sciencedirect.com/science/article/pii/S1534580724001783
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    The SPATA5-SPATA5L1 ATPase complex directs replisome proteostasis to ensure genome integrity
    2
    1. scibot 02 Apr 2024
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    2. scibot 02 Apr 2024
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    sciencedirect.com/science/article/pii/S0092867424002502
  10. Mar 2024
  11. www.sciencedirect.com www.sciencedirect.com
    ApoE maintains neuronal integrity via miRNA and H3K27me3-mediated repression.
    2
    1. scibot 07 Mar 2024
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    2. scibot 06 Mar 2024
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    sciencedirect.com/science/article/pii/S2589004224004528
  12. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Substrate-bound and soluble domains of tenascin-C regulate differentiation, proliferation and migration of neural stem and progenitor cells
    1
    1. scibot 03 Mar 2024
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    ncbi.nlm.nih.gov/pmc/articles/PMC10902920/
  13. www.cell.com www.cell.com
    Myoglobin modulates the Hippo pathway to promote cardiomyocyte differentiation.
    1
    1. scibot 02 Mar 2024
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    cell.com/iscience/abstract/S2589-0042(24)00367-5
  14. Feb 2024
  15. 52.53.155.43 52.53.155.43
    can-23-0555-html.html
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    1. scibot 23 Feb 2024
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    2. scibot 23 Feb 2024
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    3. scibot 23 Feb 2024
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    52.53.155.43/e8db3efafb8a8253e8641e16f59e9a4a6a668dad/can-23-0555-html.html
  16. www.biorxiv.org www.biorxiv.org
    Notch is Required for Neural Progenitor Proliferation During Embryonic Eye Regrowth
    1
    1. scibot 15 Feb 2024
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      DOI: 10.1101/2024.01.31.577915

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    biorxiv.org/content/10.1101/2024.01.31.577915v1
  17. www.sciencedirect.com www.sciencedirect.com
    Vibrio cholerae arrests intestinal epithelial proliferation through T6SS-dependent activation of the bone morphogenetic protein pathway
    1
    1. scibot 13 Feb 2024
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    sciencedirect.com/science/article/pii/S2211124724000780
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    SIN3A histone deacetylase action counteracts MUS81 to promote stalled fork stability
    1
    1. scibot 13 Feb 2024
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    sciencedirect.com/science/article/pii/S2211124724001062
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    Direct reprogramming of non-limb fibroblasts to cells with properties of limb progenitors
    1
    1. scibot 06 Feb 2024
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    sciencedirect.com/science/article/pii/S1534580723006901
  20. Jan 2024
  21. www.sciencedirect.com www.sciencedirect.com
    Acinar-ductal cell rearrangement drives branching morphogenesis of the murine pancreas in an IGF/PI3K-dependent manner
    1
    1. scibot 19 Jan 2024
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    sciencedirect.com/science/article/pii/S1534580723006913
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    Azithromycin preserves adult hippocampal neurogenesis and behavior in a mouse model of sepsis
    1
    1. scibot 11 Jan 2024
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    sciencedirect.com/science/article/pii/S0889159124000059
  23. www.sciencedirect.com www.sciencedirect.com
    Homology and the evolution of vocal folds in the novel avian voice box
    1
    1. scibot 10 Jan 2024
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    sciencedirect.com/science/article/pii/S0960982223016688
  24. Dec 2023
  25. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Somatostatin affects GnRH neuronal development and migration and stimulates olfactory-related fiber fasciculation
    1
    1. scibot 29 Dec 2023
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      DOI: 10.1002/dneu.22931

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    onlinelibrary.wiley.com/doi/10.1002/dneu.22931
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    Chromatin state transitions in the Drosophila intestinal lineage identify principles of cell-type specification
    1
    1. scibot 20 Dec 2023
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    sciencedirect.com/science/article/pii/S1534580723005816
  27. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Macrophages modulate fibrosis during newt lens regeneration
    1
    1. scibot 15 Dec 2023
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      DOI: 10.21203/rs.3.rs-3603645/v1

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    ncbi.nlm.nih.gov/pmc/articles/PMC10690311/
  28. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Maf1 controls retinal neuron number by both RNA Pol III- and Pol II-dependent mechanisms
    1
    1. scibot 13 Dec 2023
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    ncbi.nlm.nih.gov/pmc/articles/PMC10711482/
  29. www.sciencedirect.com www.sciencedirect.com
    Characteristics and expression of lncRNA and transposable elements in Drosophila aneuploidy
    1
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    sciencedirect.com/science/article/pii/S2589004223025713
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    Molecular underpinnings and environmental drivers of loss of heterozygosity in Drosophila intestinal stem cells
    1
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    sciencedirect.com/science/article/pii/S2211124723014973
  31. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Neocortical neuronal production and maturation defects in the TcMAC21 mouse model of Down syndrome
    1
    1. scibot 01 Dec 2023
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    ncbi.nlm.nih.gov/pmc/articles/PMC10679816/
  32. Nov 2023
  33. www.sciencedirect.com www.sciencedirect.com
    Prdm12 represses the expression of the visceral neuron determinants Phox2a/b in developing somatosensory ganglia
    1
    1. scibot 10 Nov 2023
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    sciencedirect.com/science/article/pii/S2589004223024410
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    Combined inactivation of RB and Hippo converts differentiating Drosophila photoreceptors into eye progenitor cells through derepression of homothorax
    1
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    sciencedirect.com/science/article/abs/pii/S1534580723004902
  35. Oct 2023
  36. www.sciencedirect.com www.sciencedirect.com
    The anaphase-promoting complex controls a ubiquitination-phosphoprotein axis in chromatin during neurodevelopment
    1
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    sciencedirect.com/science/article/pii/S153458072300521X
  37. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Acquisition of Neural Fate by Combination of BMP Blockade and Chromatin Modification
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC10522999/
  38. Sep 2023
  39. www.sciencedirect.com www.sciencedirect.com
    OLIG2 translocates to chromosomes during mitosis via a temperature downshift: a novel neural cold response of mitotic bookmarking
    1
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    sciencedirect.com/science/article/pii/S0378111923006704
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    Nutrient-driven dedifferentiation of enteroendocrine cells promotes adaptive intestinal growth in Drosophila
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    sciencedirect.com/science/article/abs/pii/S1534580723004379
  41. 52.53.155.43 52.53.155.43
    bqad131-html.html
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  42. Aug 2023
  43. dx.doi.org dx.doi.org
    Protective effects of imeglimin and metformin combination therapy on β-cells in db/db male mice
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      DOI: 10.1210/endocr/bqad095

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    dx.doi.org/10.1210/endocr/bqad095
  44. Jul 2023
  45. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    IGF1R inhibition enhances the therapeutic effects of Gq/11 inhibition in metastatic uveal melanoma progression
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      DOI: 10.1158/1535-7163.MCT-22-0147

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    ncbi.nlm.nih.gov/pmc/articles/PMC9812929/
  46. Jun 2023
  47. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The septate junction component bark beetle is required for Drosophila intestinal barrier function and homeostasis
    2
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    ncbi.nlm.nih.gov/pmc/articles/PMC10276166/
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    Excess pancreatic elastase alters acinar-β cell communication by impairing the mechano-signaling and the PAR2 pathways
    1
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    Neural crest-related NXPH1/α-NRXN signaling opposes neuroblastoma malignancy by inhibiting organotropic metastasis
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    The ubiquitin-ligase TRAF6 and TGFβ type I receptor form a complex with Aurora kinase B contributing to mitotic progression and cytokinesis in cancer cells
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    A junction-dependent mechanism drives murine mammary cell intercalation for ductal elongation
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    A morphogenetic wave in the chick embryo lateral mesoderm generates mesenchymal-epithelial transition through a 3D-rosette intermediate
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  61. Mar 2023
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    Arginine shortage induces replication stress and confers genotoxic resistance by inhibiting histone H4 translation and promoting PCNA ubiquitination
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    High-throughput functional analysis of autism genes in zebrafish identifies convergence in dopaminergic and neuroimmune pathways
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    Bacillus thuringiensis toxins divert progenitor cells toward enteroendocrine fate by decreasing cell adhesion with intestinal stem cells in Drosophila
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  68. Feb 2023
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    Actomyosin contractility in olfactory placode neurons opens the skin epithelium to form the zebrafish nostril
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    Co-translational protein targeting facilitates centrosomal recruitment of PCNT during centrosome maturation in vertebrates
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    Apical-basal polarity precisely determines intestinal stem cell number by regulating Prospero threshold
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    Failure of digit tip regeneration in the absence of Lmx1b suggests Lmx1b functions disparate from dorsoventral polarity
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  74. Dec 2022
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    Use of vivo-morpholinos for gene knockdown in the postnatal shark retina
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    Nucleoporins facilitate ORC loading onto chromatin
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    Establishment of 3D chromatin structure after fertilization and the metabolic switch at the morula-to-blastocyst transition require CTCF
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  93. Jun 2022
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    Replication stress triggered by nucleotide pool imbalance drives DNA damage and cGAS-STING pathway activation in NAFLD
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    A systematic characterization of microglia-like cell occurrence during retinal organoid differentiation.
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    BMP-gated cell-cycle progression drives anoikis during mesenchymal collective migration
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    Postnatal expression of cell cycle promoter Fam64a causes heart dysfunction by inhibiting cardiomyocyte differentiation through repression of Klf15
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    Nde1 is required for heterochromatin compaction and stability in neocortical neurons
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    Aspartate metabolism in endothelial cells activates the mTORC1 pathway to initiate translation during angiogenesis
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  104. Apr 2022
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    Glial-secreted Netrins regulate Robo1/Rac1-Cdc42 signaling threshold levels during Drosophila asymmetric neural stem/progenitor cell division
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    Microbiome-by-ethanol interactions impact Drosophila melanogaster fitness, physiology, and behavior
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    CHD8 haploinsufficiency links autism to transient alterations in excitatory and inhibitory trajectories
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    Essential Role of Nr2f Nuclear Receptors in Patterning the Vertebrate Upper Jaw
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    Gene copy-number changes and chromosomal instability induced by aneuploidy confer resistance to chemotherapy
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    Repeated nuclear translocations underlie photoreceptor positioning and lamination of the outer nuclear layer in the mammalian retina
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  196. elifesciences.org elifesciences.org
    Rapid changes in tissue mechanics regulate cell behaviour in the developing embryonic brain
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    Integrin β1 coordinates survival and morphogenesis of the embryonic lineage upon implantation and pluripotency transition
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    Spinal cord precursors utilize neural crest cell mechanisms to generate hybrid peripheral myelinating glia
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  199. Feb 2021
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    Drosophila female germline stem cells undergo mitosis without nuclear breakdown
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  201. Jan 2021
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    Deletion of LRP1 From Astrocytes Modifies Neuronal Network Activity in an in vitro Model of the Tripartite Synapse
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  203. www.embopress.org www.embopress.org
    Steroid‐dependent switch of OvoL/Shavenbaby controls self‐renewal versus differentiation of intestinal stem cells
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    A Disease-Causing Single Amino Acid Deletion in the Coiled-Coil Domain of RAD50 Impairs MRE11 Complex Functions in Yeast and Humans
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  205. Dec 2020
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    Regulatory T Cells Support Breast Cancer Progression by Opposing IFN-γ-Dependent Functional Reprogramming of Myeloid Cells
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    Excessive E2F Transcription in Single Cancer Cells Precludes Transient Cell-Cycle Exit after DNA Damage
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    Drosophila Tubulin-Specific Chaperone E Recruits Tubulin around Chromatin to Promote Mitotic Spindle Assembly
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    Warburg-like Metabolic Reprogramming in Aging Intestinal Stem Cells Contributes to Tissue Hyperplasia
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  210. Nov 2020
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    Myt1 Kinase Couples Mitotic Cell Cycle Exit with Differentiation in Drosophila
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    Sonic hedgehog signaling directs patterned cell remodeling during cranial neural tube closure
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  213. Oct 2020
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    Molecular Fingerprint and Developmental Regulation of the Tegmental GABAergic and Glutamatergic Neurons Derived from the Anterior Hindbrain
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    Vascular dimorphism ensured by regulated proteoglycan dynamics favors rapid umbilical artery closure at birth
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  216. Sep 2020
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    Oxygen Tension and the VHL-Hif1α Pathway Determine Onset of Neuronal Polarization and Cerebellar Germinal Zone Exit
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    Tead transcription factors differentially regulate cortical development
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    A Regulatory Program for Initiation of Wnt Signaling during Posterior Regeneration
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    The Septate Junction Protein Tsp2A Restricts Intestinal Stem Cell Activity via Endocytic Regulation of aPKC and Hippo Signaling
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  221. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Sox2‐dependent maintenance of mouse oligodendroglioma involves the Sox2‐mediated downregulation of Cdkn2b, Ebf1, Zfp423, and Hey2
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  222. dev.biologists.org dev.biologists.org
    Vessel-derived angiocrine IGF-1 promotes Meckel's cartilage proliferation to drive jaw growth during embryogenesis
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    Integrin-Mediated Focal Anchorage Drives Epithelial Zippering during Mouse Neural Tube Closure
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    Nutrient-Driven O-GlcNAcylation Controls DNA Damage Repair Signaling and Stem/Progenitor Cell Homeostasis
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    Intrauterine Pressures Adjusted by Reichert’s Membrane Are Crucial for Early Mouse Morphogenesis
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    Crossover Position Drives Chromosome Remodeling for Accurate Meiotic Chromosome Segregation
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    PRMT1-p53 Pathway Controls Epicardial EMT and Invasion
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    Quantitative Analysis of 3D Tissue Deformation Reveals Key Cellular Mechanism Associated with Initial Heart Looping
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    NCAM regulates temporal specification of neural progenitor cells via profilin2 during corticogenesisNCAM regulates temporal NPC specification
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    A transient role of the ciliary gene Inpp5e in controlling direct versus indirect neurogenesis in cortical development
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    Hox-dependent coordination of mouse cardiac progenitor cell patterning and differentiation
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    Clustered gamma-protocadherins regulate cortical interneuron programmed cell death
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    Vibrio cholerae-Symbiont Interactions Inhibit Intestinal Repair in Drosophila
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    Distinct Airway Epithelial Stem Cells Hide among Club Cells but Mobilize to Promote Alveolar Regeneration
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    ATR Restrains DNA Synthesis and Mitotic Catastrophe in Response to CDC7 Inhibition
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    Calorie Restriction Increases the Number of Competing Stem Cells and Decreases Mutation Retention in the Intestine
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