324 Matching Annotations
  1. Nov 2024
  2. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Drosophila p53 tumor suppressor directly activates conserved asymmetric stem cell division regulators
    1
    1. scibot 15 Nov 2024
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      DOI: 10.1016/j.isci.2024.111118

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    pmc.ncbi.nlm.nih.gov/articles/PMC11546965/
  3. Oct 2024
  4. www.sciencedirect.com www.sciencedirect.com
    Inactive Parp2 causes Tp53-dependent lethal anemia by blocking replication-associated nick ligation in erythroblasts
    1
    1. scibot 09 Oct 2024
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      DOI: 10.1016/j.molcel.2024.09.020

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    sciencedirect.com/science/article/pii/S1097276524007767
  5. Sep 2024
  6. www.sciencedirect.com www.sciencedirect.com
    Tissue Mechanics Regulate Mitotic Nuclear Dynamics during Epithelial Development
    1
    1. scibot 25 Sep 2024
      RRID:AB_1163440

      DOI: 10.1016/j.cub.2020.04.041

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    sciencedirect.com/science/article/pii/S0960982220305558
  7. www.sciencedirect.com www.sciencedirect.com
    Insidious chromatin change with a propensity to exhaust intestinal stem cells during aging
    1
    1. scibot 10 Sep 2024
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    sciencedirect.com/science/article/pii/S2589004224020182
  8. 52.53.155.43 52.53.155.43
    science.adh0037_sm-html.html
    1
    1. scibot 06 Sep 2024
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      DOI: 10.3389/fendo.2022.895502

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    52.53.155.43/0c103bb944ee58e95d832e9d46a2870e8663b07f/science.adh0037_sm-html.html
  9. www.sciencedirect.com www.sciencedirect.com
    Drosophila HNF4 acts in distinct tissues to direct a switch between lipid storage and export in the gut
    1
    1. scibot 05 Sep 2024
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      DOI: 10.1016/j.celrep.2024.114693

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    sciencedirect.com/science/article/pii/S2211124724010441
  10. Aug 2024
  11. www.biorxiv.org www.biorxiv.org
    tp53 R217H and R242H Mutant Zebrafish Exhibit Dysfunctional p53 Hallmarks and Recapitulate Li-Fraumeni Syndrome Phenotypes
    1
    1. scibot 20 Aug 2024
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      DOI: 10.1101/2024.07.31.605368

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    biorxiv.org/content/10.1101/2024.07.31.605368v1
  12. www.embopress.org www.embopress.org
    Foxm1 regulates neural progenitor fate during spinal cord regeneration
    1
    1. scibot 02 Aug 2024
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      DOI: 10.15252/embr.202050932

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    embopress.org/doi/full/10.15252/embr.202050932
  13. pubs.acs.org pubs.acs.org
    Cationic Hydrogels Modulate Neural Stem and Progenitor Cell Proliferation and Differentiation Behavior in Dependence of Cationic Moiety Concentration in 2D Cell Culture
    1
    1. scibot 02 Aug 2024
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      DOI: 10.1021/acsbiomaterials.3c01668

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    pubs.acs.org/doi/full/10.1021/acsbiomaterials.3c01668
  14. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Altered proliferative ability of neuronal progenitors in PlexinA1 mutant mice
    1
    1. scibot 02 Aug 2024
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      DOI: 10.1002/cne.23806

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    onlinelibrary.wiley.com/doi/10.1002/cne.23806/full
  15. Jul 2024
  16. 52.53.155.43 52.53.155.43
    paul-chowdhuri-das-2024-tdp1-phosphorylation-by-cdk1-in-mitosis-promotes-mus81-dependent-repair-of-trapped-top1-dna-html.html
    1
    1. scibot 23 Jul 2024
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      DOI: 10.1038/s44318-024-00169-3

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    52.53.155.43/697f670316e6408b23a0d9d6a185a0597054fbec/paul-chowdhuri-das-2024-tdp1-phosphorylation-by-cdk1-in-mitosis-promotes-mus81-dependent-repair-of-trapped-top1-dna-html.html
  17. www.embopress.org www.embopress.org
    TDP1 phosphorylation by CDK1 in mitosis promotes MUS81-dependent repair of trapped Top1-DNA covalent complexes
    1
    1. scibot 23 Jul 2024
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    embopress.org/doi/10.1038/s44318-024-00169-3
  18. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Warburg-like Metabolic Reprogramming in Aging Intestinal Stem Cells Contributes to Tissue Hyperplasia
    1
    1. scibot 22 Jul 2024
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      DOI: 10.1016/j.celrep.2020.108423

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    ncbi.nlm.nih.gov/pmc/articles/PMC8011352/
  19. www.cell.com www.cell.com
    Elevating PLK1 overcomes BETi resistance in prostate cancer via triggering BRD4 phosphorylation-dependent degradation in mitosis
    1
    1. scibot 12 Jul 2024
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      DOI: 10.1016/j.celrep.2024.114431

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    cell.com/cell-reports/fulltext/S2211-1247(24)00760-5
  20. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    SETDB1 regulates short interspersed nuclear elements and chromatin loop organization in mouse neural precursor cells
    1
    1. scibot 07 Jul 2024
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      DOI: 10.1186/s13059-024-03327-2

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    ncbi.nlm.nih.gov/pmc/articles/PMC11221086/
  21. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Spatially distinct epithelial and mesenchymal cell subsets along progressive lineage restriction in the branching embryonic mammary gland
    1
    1. scibot 03 Jul 2024
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      DOI: 10.1038/s44318-024-00115-3

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    ncbi.nlm.nih.gov/pmc/articles/PMC11183262/
  22. Jun 2024
  23. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Two sequential gene expression programs bridged by cell division support long-distance collective cell migration
    1
    1. scibot 13 Jun 2024
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      DOI: 10.1242/dev.202262

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    ncbi.nlm.nih.gov/pmc/articles/PMC11165717/
  24. www.sciencedirect.com www.sciencedirect.com
    Viral infection disrupts intestinal homeostasis via Sting-dependent NF-κB signaling in Drosophila
    1
    1. scibot 04 Jun 2024
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      DOI: 10.1016/j.cub.2024.05.009

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    sciencedirect.com/science/article/pii/S0960982224006079
  25. www.sciencedirect.com www.sciencedirect.com
    Gut tumors in flies alter the taste valence of an anti-tumorigenic bitter compound
    1
    1. scibot 04 Jun 2024
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      DOI: 10.1016/j.cub.2024.04.082

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    sciencedirect.com/science/article/pii/S0960982224005943
  26. May 2024
  27. www.sciencedirect.com www.sciencedirect.com
    Patterning and folding of intestinal villi by active mesenchymal dewetting
    1
    1. scibot 23 May 2024
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      DOI: 10.1016/j.cell.2024.04.039

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    sciencedirect.com/science/article/pii/S0092867424004653
  28. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Aurora-A condensation mediated by BuGZ aids its mitotic centrosome functions
    1
    1. scibot 17 May 2024
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      DOI: 10.1016/j.isci.2024.109785

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    ncbi.nlm.nih.gov/pmc/articles/PMC11090908/
  29. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Macrophages modulate fibrosis during newt lens regeneration
    1
    1. scibot 17 May 2024
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      DOI: 10.1186/s13287-024-03740-1

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    ncbi.nlm.nih.gov/pmc/articles/PMC11094960/
  30. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Cell competition promotes metastatic intestinal cancer through a multistage process
    1
    1. scibot 09 May 2024
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      DOI: 10.1016/j.isci.2024.109718

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    ncbi.nlm.nih.gov/pmc/articles/PMC11068562/
  31. Apr 2024
  32. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Numb positively regulates Hedgehog signaling at the ciliary pocket
    1
    1. scibot 29 Apr 2024
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      DOI: 10.1038/s41467-024-47244-1

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    ncbi.nlm.nih.gov/pmc/articles/PMC11045789/
  33. aacrjournals.org aacrjournals.org
    Adipose triglyceride lipase is a therapeutic target in advanced prostate cancer that promotes metabolic plasticity
    1
    1. scibot 19 Apr 2024
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      DOI: 10.1158/0008-5472.CAN-23-0555

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    aacrjournals.org/cancerres/article/84/5/703/734936/Adipose-Triglyceride-Lipase-Is-a-Therapeutic
  34. www.sciencedirect.com www.sciencedirect.com
    Dyrk1a is required for craniofacial development in Xenopus laevis.
    1
    1. scibot 16 Apr 2024
      Sigma, 06-570

      DOI: 10.1016/j.ydbio.2024.04.004

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    sciencedirect.com/science/article/pii/S001216062400099X
  35. www.sciencedirect.com www.sciencedirect.com
    Duox activation in Drosophila Malpighian tubules stimulates intestinal epithelial renewal through a countercurrent flow
    1
    1. scibot 16 Apr 2024
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      DOI: 10.1016/j.celrep.2024.114109

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    sciencedirect.com/science/article/pii/S2211124724004376
  36. www.sciencedirect.com www.sciencedirect.com
    Y chromosome damage underlies testicular abnormalities in ATR-X syndrome
    1
    1. scibot 11 Apr 2024
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    sciencedirect.com/science/article/pii/S2589004224008514
  37. www.sciencedirect.com www.sciencedirect.com
    NIBR-LTSi is a selective LATS kinase inhibitor activating YAP signaling and expanding tissue stem cells in vitro and in vivo
    1
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      DOI: 10.1016/j.stem.2024.03.003

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    sciencedirect.com/science/article/pii/S1934590924000845
  38. www.sciencedirect.com www.sciencedirect.com
    A senescence restriction point acting on chromatin integrates oncogenic signals
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    sciencedirect.com/science/article/pii/S2211124724003723
  39. www.sciencedirect.com www.sciencedirect.com
    Vangl-dependent mesenchymal thinning shapes the distal lung during murine sacculation
    1
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    sciencedirect.com/science/article/pii/S1534580724001783
  40. www.sciencedirect.com www.sciencedirect.com
    The SPATA5-SPATA5L1 ATPase complex directs replisome proteostasis to ensure genome integrity
    2
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      DOI: 10.1016/j.cell.2024.03.002

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    sciencedirect.com/science/article/pii/S0092867424002502
  41. Mar 2024
  42. www.sciencedirect.com www.sciencedirect.com
    ApoE maintains neuronal integrity via miRNA and H3K27me3-mediated repression.
    2
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      DOI: 10.1016/j.isci.2024.109231

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    sciencedirect.com/science/article/pii/S2589004224004528
  43. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Substrate-bound and soluble domains of tenascin-C regulate differentiation, proliferation and migration of neural stem and progenitor cells
    1
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      DOI: 10.3389/fncel.2024.1357499

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    ncbi.nlm.nih.gov/pmc/articles/PMC10902920/
  44. www.cell.com www.cell.com
    Myoglobin modulates the Hippo pathway to promote cardiomyocyte differentiation.
    1
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    cell.com/iscience/abstract/S2589-0042(24)00367-5
  45. Feb 2024
  46. 52.53.155.43 52.53.155.43
    can-23-0555-html.html
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    1. scibot 23 Feb 2024
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    52.53.155.43/e8db3efafb8a8253e8641e16f59e9a4a6a668dad/can-23-0555-html.html
  47. www.biorxiv.org www.biorxiv.org
    Notch is Required for Neural Progenitor Proliferation During Embryonic Eye Regrowth
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      DOI: 10.1101/2024.01.31.577915

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    SIN3A histone deacetylase action counteracts MUS81 to promote stalled fork stability
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    Acinar-ductal cell rearrangement drives branching morphogenesis of the murine pancreas in an IGF/PI3K-dependent manner
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    Somatostatin affects GnRH neuronal development and migration and stimulates olfactory-related fiber fasciculation
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    Chromatin state transitions in the Drosophila intestinal lineage identify principles of cell-type specification
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    Molecular underpinnings and environmental drivers of loss of heterozygosity in Drosophila intestinal stem cells
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    Prdm12 represses the expression of the visceral neuron determinants Phox2a/b in developing somatosensory ganglia
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    Combined inactivation of RB and Hippo converts differentiating Drosophila photoreceptors into eye progenitor cells through derepression of homothorax
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    The anaphase-promoting complex controls a ubiquitination-phosphoprotein axis in chromatin during neurodevelopment
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    Acquisition of Neural Fate by Combination of BMP Blockade and Chromatin Modification
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    OLIG2 translocates to chromosomes during mitosis via a temperature downshift: a novel neural cold response of mitotic bookmarking
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    Nutrient-driven dedifferentiation of enteroendocrine cells promotes adaptive intestinal growth in Drosophila
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    Protective effects of imeglimin and metformin combination therapy on β-cells in db/db male mice
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    IGF1R inhibition enhances the therapeutic effects of Gq/11 inhibition in metastatic uveal melanoma progression
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    The septate junction component bark beetle is required for Drosophila intestinal barrier function and homeostasis
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    Excess pancreatic elastase alters acinar-β cell communication by impairing the mechano-signaling and the PAR2 pathways
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    Neural crest-related NXPH1/α-NRXN signaling opposes neuroblastoma malignancy by inhibiting organotropic metastasis
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    MYO10 regulates genome stability and cancer inflammation through mediating mitosis
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    The ubiquitin-ligase TRAF6 and TGFβ type I receptor form a complex with Aurora kinase B contributing to mitotic progression and cytokinesis in cancer cells
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    A junction-dependent mechanism drives murine mammary cell intercalation for ductal elongation
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    A morphogenetic wave in the chick embryo lateral mesoderm generates mesenchymal-epithelial transition through a 3D-rosette intermediate
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    Coordinated growth of linked epithelia is mediated by the Hippo pathway
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  92. Mar 2023
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    Arginine shortage induces replication stress and confers genotoxic resistance by inhibiting histone H4 translation and promoting PCNA ubiquitination
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    High-throughput functional analysis of autism genes in zebrafish identifies convergence in dopaminergic and neuroimmune pathways
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    Jarid2 promotes temporal progression of retinal progenitors via repression of Foxp1
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    Dodecaploid Xenopus longipes provides insight into the emergence of size scaling relationships during development
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    V-ATPase Regulates Retinal Progenitor Cell Proliferation During Eye Regrowth in Xenopus
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  99. Feb 2023
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    Failure of digit tip regeneration in the absence of Lmx1b suggests Lmx1b functions disparate from dorsoventral polarity
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  124. Jun 2022
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    Replication stress triggered by nucleotide pool imbalance drives DNA damage and cGAS-STING pathway activation in NAFLD
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  128. May 2022
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    Postnatal expression of cell cycle promoter Fam64a causes heart dysfunction by inhibiting cardiomyocyte differentiation through repression of Klf15
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    CDK/cyclin dependencies define extreme cancer cell-cycle heterogeneity and collateral vulnerabilities
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    Human induced pluripotent stem cells display a similar mutation burden as embryonic pluripotent cells in vivo
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    Characterisation and mode of action analysis of black soldier fly (Hermetia illucens) larva derived haemocytes
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  153. Dec 2021
  154. www.nature.com www.nature.com
    Non-canonical Wnt signaling promotes directed migration of intestinal stem cells to sites of injury
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    IFI16 inhibits DNA repair that potentiates type-I interferon-induced antitumor effects in triple negative breast cancer
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  156. Nov 2021
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    Duox-generated reactive oxygen species activate ATR/Chk1 to induce G2 arrest in Drosophila tracheoblasts
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  160. Oct 2021
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    Multiscale analysis reveals that diet-dependent midgut plasticity emerges from alterations in both stem cell niche coupling and enterocyte size
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    A viral histone-like protein exploits antagonism between linker histones and HMGB proteins to obstruct the cell cycle
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  163. Sep 2021
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    Augmin deficiency in neural stem cells causes p53-dependent apoptosis and aborts brain development
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    A hydride transfer complex reprograms NAD metabolism and bypasses senescence
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  166. Aug 2021
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    Proneural genes define ground-state rules to regulate neurogenic patterning and cortical folding
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    Targeting Aurora B kinase prevents and overcomes resistance to EGFR inhibitors in lung cancer by enhancing BIM- and PUMA-mediated apoptosis
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    The dPix-Git complex is essential to coordinate epithelial morphogenesis and regulate myosin during Drosophila egg chamber development
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    Essential Role of Nr2f Nuclear Receptors in Patterning the Vertebrate Upper Jaw
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    Mechanism and function of DNA replication-independent DNA-protein crosslink repair via the SUMO-RNF4 pathway
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    Gene copy-number changes and chromosomal instability induced by aneuploidy confer resistance to chemotherapy
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    Non-nuclear Pool of Splicing Factor SFPQ Regulates Axonal Transcripts Required for Normal Motor Development
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    Repeated nuclear translocations underlie photoreceptor positioning and lamination of the outer nuclear layer in the mammalian retina
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    NEIL1 and NEIL2 DNA glycosylases protect neural crest development against mitochondrial oxidative stress
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      rabbit polyclonal anti-histone H3 (Ser10)

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    The Hippo Pathway Prevents YAP/TAZ-Driven Hypertranscription and Controls Neural Progenitor Number
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    Heparan Sulfate Proteoglycan Sulfation Regulates Uterine Differentiation and Signaling During Embryo Implantation
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  194. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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    Combined Inhibition of DYRK1A, SMAD, and Trithorax Pathways Synergizes to Induce Robust Replication in Adult Human Beta Cells
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    Repression of Interstitial Identity in Nephron Progenitor Cells by Pax2 Establishes the Nephron-Interstitium Boundary during Kidney Development
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    A Gradient of Glycolytic Activity Coordinates FGF and Wnt Signaling during Elongation of the Body Axis in Amniote Embryos
    1
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  200. onlinelibrary.wiley.com onlinelibrary.wiley.com
    The expression of tubb2b undergoes a developmental transition in murine cortical neurons
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  201. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    An actin-related protein that is most highly expressed in Drosophila testes is critical for embryonic development
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  202. www.sciencedirect.com www.sciencedirect.com
    Active elimination of intestinal cells drives oncogenic growth in organoids
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    Microenvironmental innate immune signaling and cell mechanical responses promote tumor growth
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  204. Jun 2021
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    The nuclear kinesin KIF18B promotes 53BP1-mediated DNA double-strand break repair
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  206. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    An Integrated Analysis of the Response of Colorectal Adenocarcinoma Caco-2 Cells to X-Ray Exposure
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  207. www.sciencedirect.com www.sciencedirect.com
    Polyploid mitosis and depolyploidization promote chromosomal instability and tumor progression in a Notch-induced tumor model
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  208. May 2021
  209. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Non-canonical Hedgehog signaling regulates spinal cord and muscle regeneration in Xenopus laevis larvae
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    Pluripotent stem cell-derived endometrial stromal fibroblasts in a cyclic, hormone-responsive, coculture model of human decidua
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    AHNAK controls 53BP1-mediated p53 response by restraining 53BP1 oligomerization and phase separation
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    HLTF Promotes Fork Reversal, Limiting Replication Stress Resistance and Preventing Multiple Mechanisms of Unrestrained DNA Synthesis
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    DNA Damage Promotes Epithelial Hyperplasia and Fate Mis-specification via Fibroblast Inflammasome Activation
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  214. www.sciencedirect.com www.sciencedirect.com
    A Specialized Niche in the Pancreatic Microenvironment Promotes Endocrine Differentiation
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  215. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Defects in translation-dependent quality control pathways lead to convergent molecular and neurodevelopmental pathology
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  216. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Methionine restriction breaks obligatory coupling of cell proliferation and death by an oncogene Src in Drosophila
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  217. www.sciencedirect.com www.sciencedirect.com
    Comprehensive Chromosome End Remodeling during Programmed DNA Elimination
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  218. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The essential role of Dnmt1 in gametogenesis in the large milkweed bug Oncopeltus fasciatus
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  219. Apr 2021
  220. www.sciencedirect.com www.sciencedirect.com
    Diversity in striatal synaptic circuits arises from distinct embryonic progenitor pools in the ventral telencephalon
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    Cell intercalation driven by SMAD3 underlies secondary neural tube formation
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    Topoisomerase IIα represses transcription by enforcing promoter-proximal pausing
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  223. www.sciencedirect.com www.sciencedirect.com
    Arid1a-Plagl1-Hh signaling is indispensable for differentiation-associated cell cycle arrest of tooth root progenitors
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    Cannibalized erythroblasts accelerate developmental neurogenesis by regulating mitochondrial dynamics
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  225. Mar 2021
  226. elifesciences.org elifesciences.org
    Age-related changes in polycomb gene regulation disrupt lineage fidelity in intestinal stem cells
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    Rapid changes in tissue mechanics regulate cell behaviour in the developing embryonic brain
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    Integrin β1 coordinates survival and morphogenesis of the embryonic lineage upon implantation and pluripotency transition
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  229. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Spinal cord precursors utilize neural crest cell mechanisms to generate hybrid peripheral myelinating glia
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  230. Feb 2021
  231. www.cell.com www.cell.com
    Drosophila female germline stem cells undergo mitosis without nuclear breakdown
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  232. Jan 2021
  233. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Deletion of LRP1 From Astrocytes Modifies Neuronal Network Activity in an in vitro Model of the Tripartite Synapse
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  234. www.embopress.org www.embopress.org
    Steroid‐dependent switch of OvoL/Shavenbaby controls self‐renewal versus differentiation of intestinal stem cells
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    A Disease-Causing Single Amino Acid Deletion in the Coiled-Coil Domain of RAD50 Impairs MRE11 Complex Functions in Yeast and Humans
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  236. Dec 2020
  237. www.sciencedirect.com www.sciencedirect.com
    Regulatory T Cells Support Breast Cancer Progression by Opposing IFN-γ-Dependent Functional Reprogramming of Myeloid Cells
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    Excessive E2F Transcription in Single Cancer Cells Precludes Transient Cell-Cycle Exit after DNA Damage
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  239. www.cell.com www.cell.com
    Drosophila Tubulin-Specific Chaperone E Recruits Tubulin around Chromatin to Promote Mitotic Spindle Assembly
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  240. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Warburg-like Metabolic Reprogramming in Aging Intestinal Stem Cells Contributes to Tissue Hyperplasia
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