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Adoptive macrophages suppress glioblastoma growth by reversing immunosuppressive microenvironment through programmed phenotype repolarization

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1. scibot 27 Sep 2025
  
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  DOI: 10.1016/j.celrep.2025.116350
  
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sciencedirect.com/science/article/pii/S2211124725011210
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Disruption of fibroblast MYD88 signaling promotes antitumor immunity in pancreatic ductal adenocarcinoma

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1. scibot 25 Sep 2025
  
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  DOI: 10.1016/j.celrep.2025.116347
  
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sciencedirect.com/science/article/pii/S2211124725011180
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Comparison of immunogenicity and protection efficacy of self-amplifying and circular mRNA vaccines against SARS-CoV-2

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1. scibot 23 Sep 2025
  
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  DOI: 10.1016/j.isci.2025.113498
  
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sciencedirect.com/science/article/pii/S2589004225017596
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RSK1 reprograms the ubiquitin pathway to promote immune suppression

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1. scibot 23 Sep 2025
  
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  DOI: 10.1016/j.celrep.2025.116323
  
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sciencedirect.com/science/article/pii/S2211124725010940
Sep 2025
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TIM-3 ameliorates host responses to Salmonella infection by controlling iron driven CD4+ T cell differentiation and interleukin-10 formation

1
1. scibot 16 Sep 2025
  
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  DOI: 10.1016/j.ebiom.2025.105910
  
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sciencedirect.com/science/article/pii/S2352396425003548
Aug 2025
rupress.org rupress.org

Perturbation of calreticulin potentiates CD8+ T cell–mediated antitumor immunity

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1. scibot 27 Aug 2025
  
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  DOI: 10.1084/jem.20242360
  
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rupress.org/jem/article/222/10/e20242360/278219/Perturbation-of-calreticulin-potentiates-CD8-T
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Bifidobacterium animalis suppresses non-small cell lung cancer progression and modulates tumor immunity through indole-3-acetic acid

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1. scibot 13 Aug 2025
  
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  DOI: 10.1016/j.celrep.2025.116132
  
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sciencedirect.com/science/article/pii/S2211124725009039
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CHI3L3+ immature neutrophils inhibit anti-tumor immunity and impede immune checkpoint blockade therapy in bone metastases

1
1. scibot 08 Aug 2025
  
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  DOI: 10.1016/j.ccell.2025.07.007
  
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sciencedirect.com/science/article/pii/S1535610825003137
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

USP15 Facilitates Colorectal Cancer Immune Evasion through SMYD3/CCL2-Dependent Myeloid-Derived Suppressor Cell Recruitment

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1. scibot 05 Aug 2025
  
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  DOI: 10.1158/2326-6066.CIR-24-1194
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12314529/
Jul 2025
www.nature.com www.nature.com

Manufacturing of CRISPR-edited primary mouse CAR T cells for cancer immunotherapy

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1. scibot 29 Jul 2025
  
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  DOI: 10.1038/s41596-025-01208-x
  
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nature.com/articles/s41596-025-01208-x
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CINTER-seq: Chemical profiling reveals interaction-dependent cell landscapes and gene signatures in vivo

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1. scibot 17 Jul 2025
  
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  DOI: 10.1016/j.immuni.2025.06.011
  
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sciencedirect.com/science/article/pii/S1074761325002808
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Cardiolipin-mimic lipid nanoparticles without antibody modification delivered senolytic in vivo CAR-T therapy for inflamm-aging

1
1. scibot 02 Jul 2025
  
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  RRID:AB_312661
  
  DOI: 10.1016/j.xcrm.2025.102209
  
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sciencedirect.com/science/article/pii/S2666379125002824
Jun 2025
www.thelancet.com www.thelancet.com

MyD88 signalling in B cells and antibody responses during Oropouche virus-induced neurological disease in mice

1
1. scibot 26 Jun 2025
  
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  RRID:AB_312661
  
  DOI: 10.1016/j.ebiom.2025.105815
  
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thelancet.com/journals/ebiom/article/PIIS2352-3964(25)00259-2/abstract
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Filamin A editing in myeloid cells reduces intestinal inflammation and protects from colitis

1
1. scibot 11 Jun 2025
  
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  RRID:AB_312661
  
  DOI: 10.1084/jem.20240109
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12139521/
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Immune imprinting blunts omicron pathogenicity fluctuations and highlights the essential role of cellular immunity in SARS-CoV-2 infection

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1. scibot 05 Jun 2025
  
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  DOI: 10.1016/j.celrep.2025.115784
  
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sciencedirect.com/science/article/pii/S2211124725005558
May 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

PD-1 Blockade Mitigates Surgery-Induced Immunosuppression and Increases the Efficacy of Photodynamic Therapy for Pleural Mesothelioma

1
1. scibot 28 May 2025
  
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  RRID: AB_312661
  
  DOI: 10.1158/2767-9764.CRC-24-0571
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12099492/
faseb.onlinelibrary.wiley.com faseb.onlinelibrary.wiley.com

Acyloxyacyl Hydrolase Prevents Colitis and Colitis-Associated Colorectal Cancer by Inactivating Stimulatory LPS in the Intestine

1
1. scibot 19 May 2025
  
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  RRID:AB_312661
  
  DOI: 10.1096/fj.202500310R
  
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faseb.onlinelibrary.wiley.com/doi/10.1096/fj.202500310R
Apr 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Albumin-targeted oxaliplatin(iv) prodrugs bearing STING agonists

1
1. scibot 08 Apr 2025
  
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  RRID:AB_312661
  
  DOI: 10.1039/d5qi00433k
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11969438/
pubs.rsc.org pubs.rsc.org

Albumin-targeted oxaliplatin( iv ) prodrugs bearing STING agonists

1
1. scibot 07 Apr 2025
  
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  RRID:AB_312661
  
  DOI: 10.1039/D5QI00433K
  
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pubs.rsc.org/en/content/articlehtml/2025/qi/d5qi00433k
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The metabolic sensor LKB1 regulates ILC3 homeostasis and mitochondrial function

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1. scibot 01 Apr 2025
  
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  DOI: 10.1016/j.celrep.2025.115456
  
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sciencedirect.com/science/article/pii/S221112472500227X
Mar 2025
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Targeting tumor monocyte-intrinsic PD-L1 by rewiring STING signaling and enhancing STING agonist therapy

1
1. scibot 11 Mar 2025
  
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  RRID:AB_312661
  
  DOI: 10.1016/j.ccell.2025.02.014
  
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sciencedirect.com/science/article/pii/S1535610825000662
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Temporal dynamics of immune cell transcriptomics in brain metastasis progression influenced by gut microbiome dysbiosis

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1. scibot 05 Mar 2025
  
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  DOI: 10.1016/j.celrep.2025.115356
  
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cell.com/cell-reports/abstract/S2211-1247(25)00127-5
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Integrated computational analysis identifies therapeutic targets with dual action in cancer cells and T cells

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1. scibot 04 Mar 2025
  
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  DOI: 10.1016/j.immuni.2025.02.007
  
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sciencedirect.com/science/article/pii/S107476132500072X
Feb 2025
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Selective apoptosis of tumor-associated platelets boosts the anti-metastatic potency of PD-1 blockade therapy

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1. scibot 28 Feb 2025
  
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  RRID:AB_312661
  
  DOI: 10.1016/j.xcrm.2025.101984
  
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sciencedirect.com/science/article/pii/S2666379125000576
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Potentiating anti-tumor immunity by re-engaging immune synapse molecules

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1. scibot 25 Feb 2025
  
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  RRID:AB_312661
  
  DOI: 10.1016/j.xcrm.2025.101975
  
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sciencedirect.com/science/article/pii/S2666379125000485
Jan 2025
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Identification of indirect CD4+ T cell epitopes associated with transplant rejection provides a target for donor-specific tolerance induction

1
1. scibot 31 Jan 2025
  
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  RRID:AB_312661
  
  DOI: 10.1016/j.immuni.2025.01.008
  
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sciencedirect.com/science/article/pii/S1074761325000330
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Postprandial parasympathetic signals promote lung type 2 immunity

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1. scibot 23 Jan 2025
  
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  RRID:AB_312661
  
  DOI: 10.1016/j.neuron.2024.12.020
  
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sciencedirect.com/science/article/pii/S089662732400919X
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Gut bacterial L-lysine alters metabolism and histone methylation to drive dendritic cell tolerance

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1. scibot 03 Jan 2025
  
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  DOI: 10.1016/j.celrep.2024.115125
  
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sciencedirect.com/science/article/pii/S2211124724014761
Dec 2024
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Neoadjuvant chemotherapy by liposomal doxorubicin boosts immune protection of tumor membrane antigens-based nanovaccine

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1. scibot 21 Dec 2024
  
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  DOI: 10.1016/j.xcrm.2024.101877
  
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sciencedirect.com/science/article/pii/S2666379124006487
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Different effects of fatty acid oxidation on hematopoietic stem cells based on age and diet

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1. scibot 21 Dec 2024
  
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  DOI: 10.1016/j.stem.2024.11.014
  
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sciencedirect.com/science/article/pii/S1934590924004132
52.53.155.43 52.53.155.43

can-24-1611-html.html

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1. scibot 19 Dec 2024
  
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  DOI: 10.1158/0008-5472.can-24-1611
  
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2. scibot 19 Dec 2024
  
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  DOI: 10.1158/0008-5472.can-24-1611
  
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3. scibot 19 Dec 2024
  
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  RRID:AB_312661
  
  DOI: 10.1158/0008-5472.can-24-1611
  
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52.53.155.43/75f09a51d2e08f557660a3e31ff8f3f3198b5c01/can-24-1611-html.html
Nov 2024
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Meningeal neutrophil immune signaling influences behavioral adaptation following threat

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1. scibot 24 Nov 2024
  
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  DOI: 10.1016/j.neuron.2024.10.018
  
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sciencedirect.com/science/article/pii/S0896627324007669
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Thymosin α1 reverses oncolytic adenovirus-induced M2 polarization of macrophages to improve antitumor immunity and therapeutic efficacy

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1. scibot 07 Nov 2024
  
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  RRID:AB_312661
  
  DOI: 10.1016/j.xcrm.2024.101751
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11513825/
Oct 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

MerTK+ macrophages promote melanoma progression and immunotherapy resistance through AhR-ALKAL1 activation

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1. scibot 08 Oct 2024
  
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  RRID:AB_312661
  
  DOI: 10.1126/sciadv.ado8366
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11451552/
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

CCL28 modulates neutrophil responses during infection with mucosal pathogens

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1. scibot 04 Oct 2024
  
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  RRID:AB_312661
  
  DOI: 10.7554/eLife.78206
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11444682/
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Selective translation of nuclear mitochondrial respiratory proteins reprograms succinate metabolism in AML development and chemoresistance

1
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  DOI: 10.1016/j.stem.2024.09.008
  
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The Histone Methyltransferase Setdb2 Modulates Macrophage Phenotype and Uric Acid Production in Diabetic Wound Repair

1
1. scibot 25 Sep 2024
  
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  DOI: 10.1016/j.immuni.2019.06.015
  
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Type I interferon signaling regulates myeloid and T cell crosstalk in the glioblastoma tumor microenvironment

1
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Aug 2024
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Fam49b dampens TCR signal strength to regulate survival of positively selected thymocytes and peripheral T cells

1
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  DOI: 10.7554/eLife.76940
  
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Galectin-3 induces pathogenic immunosuppressive macrophages through interaction with TREM2 in lung cancer

1
1. scibot 22 Aug 2024
  
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  DOI: 10.1186/s13046-024-03124-6
  
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CCL19-producing fibroblasts promote tertiary lymphoid structure formation enhancing anti-tumor IgG response in colorectal cancer liver metastasis

1
1. scibot 21 Aug 2024
  
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  AB_312661
  
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Baf155 controls hematopoietic differentiation and regeneration through chromatin priming

1
1. scibot 01 Aug 2024
  
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Jul 2024
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Specific targeting of cancer vaccines to antigen-presenting cells via an endogenous TLR2/6 ligand derived from cysteinyl-tRNA synthetase 1

1
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52.53.155.43 52.53.155.43

Lack of canonical thyroid hormone receptor α signaling changes regulatory T cell phenotype in female mice

1
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Kmt2c restricts G-CSF-driven HSC mobilization and granulocyte production in a methyltransferase-independent manner

2
1. scibot 25 Jul 2024
  
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  DOI: 10.1016/j.celrep.2024.114542
  
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Cellular spermine targets JAK signaling to restrain cytokine-mediated autoimmunity

1
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Clonal hematopoiesis driven by mutated DNMT3A promotes inflammatory bone loss

1
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May 2024
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Targeting the HSP47-collagen axis inhibits brain metastasis by reversing M2 microglial polarization and restoring anti-tumor immunity

1
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  DOI: 10.1016/j.xcrm.2024.101533
  
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Osr2 functions as a biomechanical checkpoint to aggravate CD8+ T cell exhaustion in tumor

1
1. scibot 14 May 2024
  
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  DOI: 10.1016/j.cell.2024.04.023
  
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BPS Publications

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  DOI: 10.1111/bph.16393
  
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bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.16393
Apr 2024
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IGSF8 is an innate immune checkpoint and cancer immunotherapy target

1
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  DOI: 10.1016/j.cell.2024.03.039
  
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Mar 2024
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Protocol to examine immune subpopulations in murine conjunctiva and lacrimal gland using flow cytometry

3
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  DOI: 10.1016/j.xpro.2024.102921
  
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  RRID:AB_312661
  
  DOI: 10.1016/j.xpro.2024.102921
  
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Feb 2024
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Anti-tumor immunotherapy using engineered bacterial outer membrane vesicles fused to lysosome-targeting chimeras mediated by transferrin receptor

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  DOI: 10.1016/j.chembiol.2024.01.002
  
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Bispecific dendritic-T cell engager potentiates anti-tumor immunity

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Deciphering the metabolic heterogeneity of hematopoietic stem cells with single-cell resolution

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sciencedirect.com/science/article/pii/S1550413123004564
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Immunotherapy targeting B cells and long-lived plasma cells effectively eliminates pre-existing donor-specific allo-antibodies

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The tumor-derived cytokine Chi3l1 induces neutrophil extracellular traps that promote T cell exclusion in triple-negative breast cancer

1
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  DOI: 10.1016/j.immuni.2023.11.002
  
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Oct 2023
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Dual-scRNA-seq analysis reveals rare and uncommon parasitized cell populations in chronic L. donovani infection

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cell.com/cell-reports/abstract/S2211-1247(23)01108-7
Sep 2023
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ALKBH5 modulates hematopoietic stem and progenitor cell energy metabolism through m6A modification-mediated RNA stability control

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Aug 2023
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mTORC2 orchestrates monocytic and granulocytic lineage commitment by an ATF5-mediated pathway

1
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  DOI: 10.1016/j.isci.2023.107540
  
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Jul 2023
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STING-IRG1 inhibits liver metastasis of colorectal cancer by regulating the polarization of tumor-associated macrophages

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Jun 2023
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Targeting PCSK9 reduces cancer cell stemness and enhances antitumor immunity in head and neck cancer

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  DOI: 10.1016/j.isci.2023.106916
  
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Methionine restriction promotes cGAS activation and chromatin untethering through demethylation to enhance antitumor immunity

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May 2023
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Airway dysbiosis accelerates lung function decline in chronic obstructive pulmonary disease

1
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  DOI: 10.1016/j.chom.2023.04.018
  
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Mechanical isolation of neonatal and adult mouse dura leukocytes for flow cytometry analysis

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Apr 2023
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SIRT2 inhibition by AGK2 enhances mycobacteria-specific stem cell memory responses by modulating beta-catenin and glycolysis

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  DOI: 10.1016/j.isci.2023.106644
  
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Harnessing matrix stiffness to engineer a bone marrow niche for hematopoietic stem cell rejuvenation

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  DOI: 10.1016/j.stem.2023.03.005
  
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ERK Inhibition Promotes Engraftment of Allografts by Reprogramming T-Cell Metabolism

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  DOI: 10.1002/advs.202206768
  
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An immune cell lipid atlas reveals the basis of susceptibility to ferroptosis

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  DOI: 10.1101/2023.02.10.528075
  
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52.53.155.43/7b3ec2d05d846404e9e7aaf3ab1e37fa63827484/2023.02.10.528075v1.full-html.html
Mar 2023
europepmc.org europepmc.org

Hematopoietic stem cells preferentially traffic misfolded proteins to aggresomes and depend on aggrephagy to maintain protein homeostasis

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Protocol for the identification and expression analysis of a cytoplasmic membrane-localized protein STING

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Feb 2023
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Pregnancy-induced changes to the gut microbiota drive macrophage pyroptosis and exacerbate septic inflammation

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TNFR2+ regulatory T cells protect against bacteremic pneumococcal pneumonia by suppressing IL-17A-producing γδ T cells in the lung

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Jan 2023
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Decoding m6A RNA methylome identifies PRMT6-regulated lipid transport promoting AML stem cell maintenance

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MHC class II-restricted antigen presentation is required to prevent dysfunction of cytotoxic T cells by blood-borne myeloids in brain tumors

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Diurnal Expression of PD-1 on Tumor-Associated Macrophages Underlies the Dosing Time-Dependent Antitumor Effects of the PD-1/PD-L1 Inhibitor BMS-1 in B16/BL6 Melanoma-Bearing Mice

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EGFR-phosphorylated GDH1 harmonizes with RSK2 to drive CREB activation and tumor metastasis in EGFR-activated lung cancer

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Across-cancer immune responses induced by nanovaccines or microvaccines to prevent different cancers and cancer metastasis

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Nov 2022
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A tick C1q protein alters infectivity of the Lyme disease agent by modulating interferon γ

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Identification of hematopoietic stem cells residing in the meninges of adult mice at steady state

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Oct 2022
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A neutrophil–B-cell axis impacts tissue damage control in a mouse model of intraabdominal bacterial infection via Cxcr4

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pmc.ncbi.nlm.nih.gov/articles/PMC9525059/
Aug 2022
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Enterobacter ludwigii protects DSS-induced colitis through choline-mediated immune tolerance

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Faecalibaculum rodentium remodels retinoic acid signaling to govern eosinophil-dependent intestinal epithelial homeostasis

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Phospholipid metabolites of the gut microbiota promote hypoxia-induced intestinal injury via CD1d-dependent γδ T cells

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ncbi.nlm.nih.gov/pmc/articles/PMC9336479/
Jul 2022
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Nanocarriers based on bacterial membrane materials for cancer vaccine delivery

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nature.com/articles/s41596-022-00713-7
Jun 2022
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Androgens drive sexual dimorphism in liver metastasis by promoting hepatic accumulation of neutrophils

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May 2022
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Lymph node colonization induces tumor-immune tolerance to promote distant metastasis

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Apr 2022
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ILC precursors differentiate into metabolically distinct ILC1-like cells during Mycobacterium tuberculosis infection

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Microbiota-dependent activation of the myeloid calcineurin-NFAT pathway inhibits B7H3- and B7H4-dependent anti-tumor immunity in colorectal cancer

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Feb 2022
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ICAM-1-mediated adhesion is a prerequisite for exosome-induced T cell suppression

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Jan 2022
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ACE2 is the critical in vivo receptor for SARS-CoV-2 in a novel COVID-19 mouse model with TNF- and IFNγ-driven immunopathology

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ncbi.nlm.nih.gov/pmc/articles/PMC8776253/
Dec 2021
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Parity-induced changes to mammary epithelial cells control NKT cell expansion and mammary oncogenesis

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Sep 2021
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Protocol for analyzing and visualizing antiviral immune responses after acute infection of the murine oral mucosa

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Aug 2021
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Aspartate availability limits hematopoietic stem cell function during hematopoietic regeneration

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Hsf1 promotes hematopoietic stem cell fitness and proteostasis in response to ex vivo culture stress and aging

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Selective loss of resident macrophage-derived insulin-like growth factor-1 abolishes adaptive cardiac growth to stress

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Untitled document

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Jun 2021
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DHX15 is required to control RNA virus-induced intestinal inflammation

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A systematic CRISPR screen reveals an IL-20/IL20RA-mediated immune crosstalk to prevent the ovarian cancer metastasis

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May 2021
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Single-Cell Analysis of Neonatal HSC Ontogeny Reveals Gradual and Uncoordinated Transcriptional Reprogramming that Begins before Birth

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Group 1 innate lymphoid-cell-derived interferon-γ maintains anti-viral vigilance in the mucosal epithelium

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Substance P Release by Sensory Neurons Triggers Dendritic Cell Migration and Initiates the Type-2 Immune Response to Allergens

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Apr 2021
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Notch4 signaling limits regulatory T-cell-mediated tissue repair and promotes severe lung inflammation in viral infections

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Feb 2021
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A Universal Design of Betacoronavirus Vaccines against COVID-19, MERS, and SARS

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Kmt2c mutations enhance HSC self-renewal capacity and convey a selective advantage after chemotherapy

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Sep 2020
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CD49a Regulates Cutaneous Resident Memory CD8+ T Cell Persistence and Response

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1. scibot 16 Sep 2020
  
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  RRID:AB_312661
  
  DOI: 10.1016/j.celrep.2020.108085
  
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Leukemogenic Chromatin Alterations Promote AML Leukemia Stem Cells via a KDM4C-ALKBH5-AXL Signaling Axis

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1. scibot 07 Sep 2020
  
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  DOI: 10.1016/j.stem.2020.04.001
  
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sciencedirect.com/science/article/pii/S1934590920301405
Jan 2020
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Restricted Hematopoietic Progenitors and Erythropoiesis Require SCF from Leptin Receptor+ Niche Cells in the Bone Marrow

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1. scibot 13 Jan 2020
  
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  DOI: 10.1016/j.stem.2018.11.022
  
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ncbi.nlm.nih.gov/pmc/articles/PMC6813769/
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Untitled document

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1. scibot 13 Jan 2020
  
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  DOI: 10.1016/j.stem.2018.11.022
  
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sciencedirect.com/science/article/pii/S1934590918305587
Nov 2018
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Lung Single-Cell Signaling Interaction Map Reveals Basophil Role in Macrophage Imprinting

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1. scibot 05 Nov 2018
  
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sciencedirect.com/science/article/pii/S0092867418311814
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Airway Epithelial Cell-Derived Colony Stimulating Factor-1 Promotes Allergen Sensitization

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1. scibot 05 Nov 2018
  
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sciencedirect.com/science/article/pii/S1074761318302917
Nov 2017
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Induction of Live Cell Phagocytosis by a Specific Combination of Inflammatory Stimuli

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1. scibot 08 Nov 2017
  
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sciencedirect.com/science/article/pii/S2352396417302840

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