49 Matching Annotations
  1. Jun 2024
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    Clonal hematopoiesis driven by mutated DNMT3A promotes inflammatory bone loss
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    sciencedirect.com/science/article/pii/S0092867424004926
  3. May 2024
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    Development of a PAK4-targeting PROTAC for renal carcinoma therapy: concurrent inhibition of cancer cell proliferation and enhancement of immune cell response
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    The Gut Microbiome Controls Liver Tumors via the Vagus Nerve
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    1. scibot 09 May 2024
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  6. Apr 2024
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    Endothelial cell expression of a STING gain-of-function mutation initiates pulmonary lymphocytic infiltration
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    sciencedirect.com/science/article/pii/S221112472400442X
  8. Mar 2024
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    Differentiation route determines the functional outputs of adult megakaryopoiesis
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  10. Feb 2024
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    An axon-T cell feedback loop enhances inflammation and axon degeneration
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    sciencedirect.com/science/article/pii/S2211124724000494
  12. Jan 2024
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    Deciphering the metabolic heterogeneity of hematopoietic stem cells with single-cell resolution
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    sciencedirect.com/science/article/pii/S1550413123004564
  14. Dec 2023
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    Non-canonical Hedgehog signaling mediates profibrotic hematopoiesis-stroma crosstalk in myeloproliferative neoplasms
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    sciencedirect.com/science/article/pii/S2211124723016200
  16. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    FGFR3 alterations in bladder cancer stimulate serine synthesis to induce immune-inert macrophages that suppress T-cell recruitment and activation
    1
    1. scibot 20 Dec 2023
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  17. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A gut-restricted glutamate carboxypeptidase II inhibitor reduces monocytic inflammation and improves preclinical colitis
    1
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  18. 52.53.155.43 52.53.155.43
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  19. Oct 2023
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    Stress regulates Alzheimer’s disease progression via selective enrichment of CD8+ T cells
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    1. scibot 27 Oct 2023
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    sciencedirect.com/science/article/pii/S2211124723013256
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    Lipid accumulation-mediated histone hypoacetylation drives persistent NK cell dysfunction in anti-tumor immunity
    1
    1. scibot 13 Oct 2023
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    sciencedirect.com/science/article/pii/S2211124723012238
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    Targeting LYPLAL1-mediated cGAS depalmitoylation enhances the response to anti-tumor immunotherapy
    1
    1. scibot 13 Oct 2023
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      DOI: 10.1016/j.molcel.2023.09.007

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    sciencedirect.com/science/article/pii/S1097276523007025
  23. Aug 2023
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    METTL3 drives NAFLD-related hepatocellular carcinoma and is a therapeutic target for boosting immunotherapy
    1
    1. scibot 16 Aug 2023
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    sciencedirect.com/science/article/pii/S2666379123002975
  25. Jun 2023
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    Systematic dissection of coordinated stromal remodeling identifies Sox10+ glial cells as a therapeutic target in myelofibrosis
    1
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  27. May 2023
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    A local subset of mesenchymal cells expressing the transcription factor Osr1 orchestrates lymph node initiation
    1
    1. scibot 10 May 2023
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    sciencedirect.com/science/article/pii/S1074761323001826
  29. link.springer.com link.springer.com
    Co-modulation of TNFR1 and TNFR2 in an animal model of multiple sclerosis
    1
    1. scibot 02 May 2023
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      DOI: 10.1186/s12974-023-02784-z

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    link.springer.com/article/10.1186/s12974-023-02784-z
  30. Apr 2023
  31. www.sciencedirect.com www.sciencedirect.com
    Harnessing matrix stiffness to engineer a bone marrow niche for hematopoietic stem cell rejuvenation
    1
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    sciencedirect.com/science/article/pii/S1934590923000760
  32. 52.53.155.43 52.53.155.43
    An immune cell lipid atlas reveals the basis of susceptibility to ferroptosis
    1
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      DOI: 10.1101/2023.02.10.528075

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    52.53.155.43/7b3ec2d05d846404e9e7aaf3ab1e37fa63827484/2023.02.10.528075v1.full-html.html
  33. Mar 2023
  34. europepmc.org europepmc.org
    Hematopoietic stem cells preferentially traffic misfolded proteins to aggresomes and depend on aggrephagy to maintain protein homeostasis
    1
    1. scibot 28 Mar 2023
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    europepmc.org/article/med/36948186
  35. Jan 2023
  36. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A Genome-wide screen identifies PDPK1 as a target to enhance the efficacy of MEK1/2 inhibitors in NRAS mutant melanoma
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    1. scibot 20 Jan 2023
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      DOI: 10.1158/0008-5472.CAN-21-3217

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    ncbi.nlm.nih.gov/pmc/articles/PMC9298960/
  37. www.biorxiv.org www.biorxiv.org
    An axon – T cell feedback loop enhances inflammation and axon degeneration
    1
    1. scibot 12 Jan 2023
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      DOI: 10.1101/2023.01.06.523014

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    biorxiv.org/content/10.1101/2023.01.06.523014v1
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    Tissue resident iNKT17 cells facilitate cancer cell extravasation in liver metastasis via interleukin-22
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    T cell-derived interleukin-22 drives the expression of CD155 by cancer cells to suppress NK cell function and promote metastasis
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    1. scibot 12 Jan 2023
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    Microbiota-dependent and -independent postnatal development of salivary immunity
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    1. scibot 10 Jan 2023
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    sciencedirect.com/science/article/pii/S221112472201885X
  41. Dec 2022
  42. link.springer.com link.springer.com
    RAGE deficiency ameliorates autoimmune hepatitis involving inhibition of IL-6 production via suppressing protein Arid5a in mice
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      DOI: 10.1007/s10238-022-00960-8

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    link.springer.com/article/10.1007/s10238-022-00960-8
  43. Sep 2022
  44. www.sciencedirect.com www.sciencedirect.com
    Immune chromatin reader SP140 regulates microbiota and risk for inflammatory bowel disease
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    sciencedirect.com/science/article/pii/S1931312822004176
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    ATF3 and CH25H regulate effector trogocytosis and anti-tumor activities of endogenous and immunotherapeutic cytotoxic T lymphocytes
    1
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    sciencedirect.com/science/article/pii/S1550413122003503
  46. Jun 2022
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    Bone marrow hematopoiesis drives multiple sclerosis progression
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    sciencedirect.com/science/article/pii/S0092867422006511
  48. Apr 2022
  49. www.sciencedirect.com www.sciencedirect.com
    Developmental maturation of the hematopoietic system controlled by a Lin28b-let-7-Cbx2 axis
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  50. Dec 2021
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    Virulence factors perforate the pathogen-containing vacuole to signal efferocytosis
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    sciencedirect.com/science/article/pii/S1931312821005667
  52. Aug 2021
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    Hsf1 promotes hematopoietic stem cell fitness and proteostasis in response to ex vivo culture stress and aging
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  54. Jul 2021
  55. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Untitled document
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      DOI: 10.1016/j.molcel.2018.08.042

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    A Cellular Taxonomy of the Bone Marrow Stroma in Homeostasis and Leukemia
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  57. May 2021
  58. www.sciencedirect.com www.sciencedirect.com
    Single-Cell Analysis of Neonatal HSC Ontogeny Reveals Gradual and Uncoordinated Transcriptional Reprogramming that Begins before Birth
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    sciencedirect.com/science/article/pii/S1934590920303970
  59. Apr 2021
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    Maturation of the neonatal oral mucosa involves unique epithelium-microbiota interactions
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    Gut microbial metabolites facilitate anticancer therapy efficacy by modulating cytotoxic CD8+ T cell immunity
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    sciencedirect.com/science/article/pii/S1550413121001091
  62. Mar 2021
  63. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    IL-15/IL-15Rα Heterodimeric Complex as Cancer Immunotherapy in Murine Breast Cancer Models
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  64. Feb 2021
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    DNA Sensing in Mismatch Repair-Deficient Tumor Cells Is Essential for Anti-tumor Immunity
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    Kmt2c mutations enhance HSC self-renewal capacity and convey a selective advantage after chemotherapy
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  67. Sep 2020
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    Marginal Zone Formation Requires ACKR3 Expression on B Cells
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    Visualization of T Cell Migration in the Spleen Reveals a Network of Perivascular Pathways that Guide Entry into T Zones
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    Influenza Virus Z-RNAs Induce ZBP1-Mediated Necroptosis
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  71. Jan 2020
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    S100A4 Protein Is Essential for the Development of Mature Microfold Cells in Peyer’s Patches
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  73. Nov 2018
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    SIRT1 Activation Disrupts Maintenance of Myelodysplastic Syndrome Stem and Progenitor Cells by Restoring TET2 Function
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