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Engineering T Cells with a Tumor-Reactive Chimeric T Cell Receptor Reduces Exhaustion and Promotes Persistence to Elicit Enhanced Antitumor Responses

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1. scibot 11 Jul 2026
  
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  DOI: 10.1158/0008-5472.CAN-25-0777
  
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aacrjournals.org/cancerres/article/86/11/2688/785304/Engineering-T-Cells-with-a-Tumor-Reactive-Chimeric
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Targeting cholesterol esterification sensitizes liver cancer to CD8+ T cell attack by impairing metabolic and redox resilience

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1. scibot 07 Jul 2026
  
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  DOI: 10.1016/j.immuni.2026.06.002
  
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sciencedirect.com/science/article/pii/S1074761326002530
May 2026
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Circulating extracellular vesicle microRNAs mediate immune modulation of social behavior in male mice

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1. scibot 30 May 2026
  
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  DOI: 10.1038/s41467-026-70469-1
  
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pmc.ncbi.nlm.nih.gov/articles/PMC13216276/
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Newly isolated human-derived Lactobacillus fermentum strain stimulates IFN-γ-secreting CD8+ T cells for enhanced anti-cancer immunity

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1. scibot 01 May 2026
  
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  DOI: 10.1016/j.isci.2026.115642
  
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pmc.ncbi.nlm.nih.gov/articles/PMC13125905/
Mar 2026
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Myofibroblast programming blocks differentiation of TLS-organizing fibroblastic reticular cells in pancreatic cancer

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1. scibot 27 Mar 2026
  
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  DOI: 10.1016/j.ccell.2026.03.004
  
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sciencedirect.com/science/article/pii/S153561082600156X
Feb 2026
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Vascular normalization by erianin unleashes CAR-T immunotherapy in glioblastoma

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1. scibot 26 Feb 2026
  
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  DOI: 10.1007/s10456-026-10031-1
  
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link.springer.com/article/10.1007/s10456-026-10031-1
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Syndecan-1-targeted therapeutic antibody impairs macropinocytosis and elicits antitumor immunity in pancreatic cancer

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1. scibot 19 Feb 2026
  
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  DOI: 10.1016/j.xcrm.2026.102613
  
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sciencedirect.com/science/article/pii/S2666379126000303
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A pan-cancer single-cell transcriptomic atlas of human bone metastases

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1. scibot 03 Feb 2026
  
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  DOI: 10.1016/j.xcrm.2025.102583
  
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sciencedirect.com/science/article/pii/S2666379125006561
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Targeting immune cells in the aged brain reveals that engineered cytokine IL-10 enhances neurogenesis and improves cognition

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1. scibot 03 Feb 2026
  
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  DOI: 10.1016/j.immuni.2026.01.016
  
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sciencedirect.com/science/article/pii/S1074761326000385
Dec 2025
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Dysplastic epithelial repair promotes the tissue residence of lymphocytes to inhibit alveolar regeneration post viral infection

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1. scibot 23 Dec 2025
  
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  DOI: 10.1016/j.stem.2025.12.005
  
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sciencedirect.com/science/article/pii/S1934590925004394
www.sciencedirect.com:5037 www.sciencedirect.com:5037

Microbial-derived immunostimulatory small molecule augments anti-PD-1 therapy in lung cancer

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1. scibot 20 Dec 2025
  
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  DOI: 10.1016/j.xcrm.2025.102519
  
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sciencedirect.com:5037/science/article/pii/S2666379125005920
Aug 2025
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CHI3L3+ immature neutrophils inhibit anti-tumor immunity and impede immune checkpoint blockade therapy in bone metastases

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1. scibot 08 Aug 2025
  
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  DOI: 10.1016/j.ccell.2025.07.007
  
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sciencedirect.com/science/article/pii/S1535610825003137
Jul 2025
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Mitochondrial complex IV remodeling in tumor-associated macrophages amplifies interferon signaling and promotes anti-tumor immunity

1
1. scibot 01 Jul 2025
  
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  DOI: 10.1016/j.immuni.2025.06.006
  
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sciencedirect.com/science/article/pii/S1074761325002754
May 2025
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Sickle cell disease induces chromatin introversion and ferroptosis in CD8+ T cells to suppress anti-tumor immunity

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1. scibot 17 May 2025
  
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  RRID:AB_312667
  
  DOI: 10.1016/j.immuni.2025.04.020
  
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sciencedirect.com/science/article/pii/S1074761325001839
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Tumor microenvironment-associated oxidative stress impairs SIRT1 secretion to suppress anti-tumor immune response

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1. scibot 17 May 2025
  
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  DOI: 10.1016/j.celrep.2025.115679
  
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sciencedirect.com/science/article/pii/S2211124725004504
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Bone metastases diminish extraosseous response to checkpoint blockade immunotherapy through osteopontin-producing osteoclasts

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1. scibot 16 May 2025
  
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  RRID:AB_312667
  
  DOI: 10.1016/j.ccell.2025.03.036
  
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sciencedirect.com/science/article/pii/S1535610825001370
Jan 2025
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Targeted localization of the mother centrosome in CD8+ T cells undergoing asymmetric cell division promotes memory formation

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1. scibot 07 Jan 2025
  
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  RRID:AB_312667
  
  DOI: 10.1016/j.celrep.2024.115127
  
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sciencedirect.com/science/article/pii/S2211124724014785
Aug 2024
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Epithelial organoid supports resident memory CD8 T cell differentiation

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1. scibot 22 Aug 2024
  
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  AB_312667
  
  DOI: 10.1016/j.celrep.2024.114621
  
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sciencedirect.com/science/article/pii/S2211124724009719
www.cell.com www.cell.com

The amalgam of naive CD4+ T cell transcriptional states is reconfigured by helminth infection to dampen the amplitude of the immune response

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1. scibot 18 Aug 2024
  
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  RRID:AB_312667
  
  DOI: 10.1016/j.immuni.2024.07.006
  
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cell.com/immunity/fulltext/S1074-7613(24)00355-8
Jul 2024
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Neuronal-enriched small extracellular vesicles trigger a PD-L1-mediated broad suppression of T cells in Parkinson’s disease

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1. scibot 10 Jul 2024
  
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  RRID:AB_312667
  
  DOI: 10.1016/j.isci.2024.110243
  
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sciencedirect.com/science/article/pii/S2589004224014688
Oct 2023
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

High NEK2 expression in myeloid progenitors suppresses T cell immunity in multiple myeloma

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1. scibot 14 Oct 2023
  
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  RRID:AB_312667
  
  DOI: 10.1016/j.xcrm.2023.101214
  
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2. scibot 14 Oct 2023
  
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  RRID:AB_312667
  
  DOI: 10.1016/j.xcrm.2023.101214
  
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pmc.ncbi.nlm.nih.gov/articles/PMC10591052/
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Neutrophils resist ferroptosis and promote breast cancer metastasis through aconitate decarboxylase 1

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1. scibot 13 Oct 2023
  
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  DOI: 10.1016/j.cmet.2023.09.004
  
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sciencedirect.com/science/article/pii/S1550413123003364
Jul 2023
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Development of a DNA aptamer targeting IDO1 with anti-tumor effects

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1. scibot 27 Jul 2023
  
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  DOI: 10.1016/j.isci.2023.107367
  
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sciencedirect.com/science/article/pii/S258900422301444X
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A genetic method specifically delineates Th1-type Treg cells and their roles in tumor immunity

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1. scibot 13 Jul 2023
  
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  DOI: 10.1016/j.celrep.2023.112813
  
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sciencedirect.com/science/article/pii/S2211124723008240
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Extracellular Vesicle Secretion by Leukemia Cells In Vivo Promotes CLL Progression by Hampering Antitumor T-cell Responses

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1. scibot 08 Jul 2023
  
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  DOI: 10.1158/2643-3230.BCD-22-0029
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9816815/
Jun 2023
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Quantitative control of Ets1 dosage by a multi-enhancer hub promotes Th1 cell differentiation and protects from allergic inflammation

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1. scibot 01 Jun 2023
  
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  DOI: 10.1016/j.immuni.2023.05.004
  
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sciencedirect.com/science/article/pii/S1074761323002212
Jan 2023
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T cell-derived interleukin-22 drives the expression of CD155 by cancer cells to suppress NK cell function and promote metastasis

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1. scibot 12 Jan 2023
  
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  DOI: 10.1016/j.immuni.2022.12.010
  
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sciencedirect.com/science/article/pii/S107476132200646X
Aug 2022
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Transcription Elongation Machinery Is a Druggable Dependency and Potentiates Immunotherapy in Glioblastoma Stem Cells

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1. scibot 04 Aug 2022
  
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  DOI: 10.1158/2159-8290.CD-20-1848
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8831451/
May 2022
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Binary outcomes of enhancer activity underlie stable random monoallelic expression

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1. scibot 28 May 2022
  
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  DOI: 10.7554/eLife.74204
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9135403/
Mar 2022
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Activation of regulatory T cells triggers specific changes in glycosylation associated with Siglec-1-dependent inflammatory responses

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1. scibot 04 Mar 2022
  
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  DOI: 10.12688/wellcomeopenres.16834.1
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8844539/
Dec 2021
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DOCK8-expressing T follicular helper cells newly generated beyond self-organized criticality cause systemic lupus erythematosus

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1. scibot 17 Dec 2021
  
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  AB_312667
  
  DOI: 10.1016/j.isci.2021.103537
  
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sciencedirect.com/science/article/pii/S258900422101508X
Nov 2021
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The allergy mediator histamine confers resistanceto immunotherapy in cancer patients via activationof the macrophage histamine receptor H1

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1. scibot 25 Nov 2021
  
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  DOI: 10.1016/j.ccell.2021.11.002
  
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sciencedirect.com/science/article/pii/S1535610821006024
Sep 2021
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Tissue environment, not ontogeny, defines murine intestinal intraepithelial T lymphocytes

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1. scibot 30 Sep 2021
  
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  DOI: 10.7554/eLife.70055
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8463072/
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Dietary suppression of MHC class II expression in intestinal epithelial cells enhances intestinal tumorigenesis

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1. scibot 17 Sep 2021
  
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  DOI: 10.1016/j.stem.2021.08.007
  
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sciencedirect.com/science/article/pii/S1934590921003441
Aug 2021
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Untitled document

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1. scibot 12 Aug 2021
  
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  DOI: 10.1016/j.cmet.2017.08.008
  
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Splicing factor SRSF1 is indispensable for regulatory T cell homeostasis and function

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Pharmacologic modulation of RNA splicing enhances anti-tumor immunity

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Role of nuclear localization in the regulation and function of T-bet and Eomes in exhausted CD8 T cells

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In vivo CD8+ T cell CRISPR screening reveals control by Fli1 in infection and cancer

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Metabolic modulation by CDK4/6 inhibitor promotes chemokine-mediated recruitment of T cells into mammary tumors

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Cytotoxic T cells swarm by homotypic chemokine signalling

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Hhex Directly Represses BIM-Dependent Apoptosis to Promote NK Cell Development and Maintenance

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A Stat6/Pten Axis Links Regulatory T Cells with Adipose Tissue Function

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Formation of Human Neuroblastoma in Mouse-Human Neural Crest Chimeras

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Formation of Human Neuroblastoma in Mouse-Human Neural Crest Chimeras

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Differences in Tumor Microenvironment Dictate T Helper Lineage Polarization and Response to Immune Checkpoint Therapy

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Macroautophagy in Dendritic Cells Controls the Homeostasis and Stability of Regulatory T Cells

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TCF-1-Centered Transcriptional Network Drives an Effector versus Exhausted CD8 T Cell-Fate Decision

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Disrupting Myelin-Specific Th17 Cell Gut Homing Confers Protection in an Adoptive Transfer Experimental Autoimmune Encephalomyelitis

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Langerhans Cells Orchestrate the Protective Antiviral Innate Immune Response in the Lymph Node

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Dysregulated IL-18 Is a Key Driver of Immunosuppression and a Possible Therapeutic Target in the Multiple Myeloma Microenvironment

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Initiation of Antiviral B Cell Immunity Relies on Innate Signals from Spatially Positioned NKT Cells

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A Stat6/Pten Axis Links Regulatory T Cells with Adipose Tissue Function

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