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  1. Last 7 days
  2. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    p21 regulates expression of ECM components and promotes pulmonary fibrosis via CDK4 and Rb
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    1. scibot 21 Nov 2024
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      DOI: 10.1038/s44318-024-00246-7

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    pmc.ncbi.nlm.nih.gov/articles/PMC11574164/
  3. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    CD4+ T cells with convergent TCR recombination reprogram stroma and halt tumor progression in adoptive therapy
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    1. scibot 17 Nov 2024
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      DOI: 10.1126/sciimmunol.adp6529

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    pmc.ncbi.nlm.nih.gov/articles/PMC11560124/
  4. Nov 2024
  5. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Development of a CD39 nanobody and its enhancement to chimeric antigen receptor T cells efficacy against ovarian cancer in preclinical studies
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    1. scibot 07 Nov 2024
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      DOI: 10.7150/thno.97590

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    pmc.ncbi.nlm.nih.gov/articles/PMC11488103/
  6. Aug 2024
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    Indirect suppression of CD4 T cell activation through LAG-3-mediated trans-endocytosis of MHC class II
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    1. scibot 27 Aug 2024
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    sciencedirect.com/science/article/pii/S2211124724010064
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    CD38-NAD+Axis Regulates Immunotherapeutic Anti-Tumor T Cell Response
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    1. scibot 21 Aug 2024
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      DOI: 10.1016/j.cmet.2017.10.006

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    sciencedirect.com/science/article/pii/S1550413117306186
  9. Jul 2024
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    A Th17 cell-intrinsic glutathione/mitochondrial-IL-22 axis protects against intestinal inflammation
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    sciencedirect.com/science/article/pii/S1550413124002353
  11. www.cell.com www.cell.com
    Mitochondrial DNA-boosted dendritic cell-based nanovaccination triggers antitumor immunity in lung and pancreatic cancers
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    1. scibot 12 Jul 2024
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      DOI: 10.1016/j.xcrm.2024.101648

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    cell.com/cell-reports-medicine/fulltext/S2666-3791(24)00362-8
  12. May 2024
  13. www.sciencedirect.com www.sciencedirect.com
    A targeted single mutation in influenza A virus universal epitope transforms immunogenicity and protective immunity via CD4+ T cell activation
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    1. scibot 31 May 2024
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    sciencedirect.com/science/article/pii/S2211124724005874
  14. Apr 2024
  15. www.sciencedirect.com www.sciencedirect.com
    CD80 on skin stem cells promotes local expansion of regulatory T cells upon injury to orchestrate repair within an inflammatory environment
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    1. scibot 30 Apr 2024
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    sciencedirect.com/science/article/pii/S1074761324002085
  16. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The CD4 transmembrane GGXXG and juxtamembrane (C/F)CV+C motifs mediate pMHCII-specific signaling independently of CD4-LCK interactions
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    1. scibot 23 Apr 2024
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      DOI: 10.7554/eLife.88225

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    ncbi.nlm.nih.gov/pmc/articles/PMC11031086/
  17. Dec 2023
  18. www.sciencedirect.com www.sciencedirect.com
    Emulsion and liposome-based adjuvanted R21 vaccine formulations mediate protection against malaria through distinct immune mechanisms
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    1. scibot 02 Dec 2023
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    sciencedirect.com/science/article/pii/S2666379123004226
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    Sensory neuronal STAT3 is critical for IL-31 receptor expression and inflammatory itch
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    1. scibot 02 Dec 2023
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    sciencedirect.com/science/article/pii/S2211124723014456
  20. Nov 2023
  21. www.sciencedirect.com www.sciencedirect.com
    Keratinocyte FABP5-VCP complex mediates recruitment of neutrophils in psoriasis
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    1. scibot 28 Nov 2023
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    sciencedirect.com/science/article/pii/S2211124723014614
  22. Oct 2023
  23. www.sciencedirect.com www.sciencedirect.com
    Effector memory T cells induce innate inflammation by triggering DNA damage and a non-canonical STING pathway in dendritic cells
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    1. scibot 14 Oct 2023
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      DOI: 10.1016/j.celrep.2023.113180

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    sciencedirect.com/science/article/pii/S2211124723011920
  24. Aug 2023
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    IL-2 can signal via chemokine receptors to promote regulatory T cells’ suppressive function
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    1. scibot 23 Aug 2023
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      DOI: 10.1016/j.celrep.2023.112996

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    sciencedirect.com/science/article/pii/S2211124723010070
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    S100A8/A9-alarmin promotes local myeloid-derived suppressor cell activation restricting severe autoimmune arthritis
    1
    1. scibot 23 Aug 2023
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    sciencedirect.com/science/article/pii/S2211124723010173
  27. Jun 2023
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    Coupled deglycosylation-ubiquitination cascade in regulating PD-1 degradation by MDM2
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    sciencedirect.com/science/article/pii/S2211124723007040
  29. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Polycomb repressive complex 1.1 coordinates homeostatic and emergency myelopoiesis
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      DOI: 10.7554/eLife.83004

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    ncbi.nlm.nih.gov/pmc/articles/PMC10287155/
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    Gasdermin D licenses MHCII induction to maintain food tolerance in small intestine
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    1. scibot 21 Jun 2023
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      DOI: 10.1016/j.cell.2023.05.027

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    sciencedirect.com/science/article/pii/S0092867423005779
  31. 52.53.155.43 52.53.155.43
    RORψt+CD4+ T cells promote IL-23R-mediated neuronal cell apoptosis in the central nervous system
    1
    1. scibot 01 Jun 2023
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      DOI: 10.1101/2023.04.17.537133

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    52.53.155.43/333ed306ab43198840b04e278f040205d2c57b40/2023.04.17.537133v1.full-html.html
  32. May 2023
  33. www.sciencedirect.com www.sciencedirect.com
    Remodeling of the immune and stromal cell compartment by PD-1 blockade in mismatch repair-deficient colorectal cancer
    1
    1. scibot 12 May 2023
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      DOI: 10.1016/j.ccell.2023.04.011

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    sciencedirect.com/science/article/pii/S153561082300137X
  34. Apr 2023
  35. 52.53.155.43 52.53.155.43
    Cooperative super-enhancer inactivation caused by heterozygous loss of CREBBP and KMT2D skews B cell fate decisions and yields T cell-depleted lymphomas
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    1. scibot 05 Apr 2023
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      DOI: 10.1101/2023.02.13.528351

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    52.53.155.43/f4b0048cc7a871a681c39b83d20e963f1e4d0c2b/2023.02.13.528351v1.full-html.html
  36. Mar 2023
  37. europepmc.org europepmc.org
    Hematopoietic stem cells preferentially traffic misfolded proteins to aggresomes and depend on aggrephagy to maintain protein homeostasis
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    1. scibot 28 Mar 2023
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      DOI: 10.1016/j.stem.2023.02.010

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    europepmc.org/article/med/36948186
  38. www.sciencedirect.com www.sciencedirect.com
    Pyruvate dehydrogenase fuels a critical citrate pool that is essential for Th17 cell effector functions
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      DOI: 10.1016/j.celrep.2023.112153

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    sciencedirect.com/science/article/pii/S221112472300164X
  39. Jan 2023
  40. www.sciencedirect.com www.sciencedirect.com
    Decoding m6A RNA methylome identifies PRMT6-regulated lipid transport promoting AML stem cell maintenance
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      DOI: 10.1016/j.stem.2022.12.003

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    sciencedirect.com/science/article/pii/S1934590922004878
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    Microbiota-dependent proteolysis of gluten subverts diet-mediated protection against type 1 diabetes
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      DOI: 10.1016/j.chom.2022.12.009

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    sciencedirect.com/science/article/pii/S1931312822006102
  42. Dec 2022
  43. www.sciencedirect.com www.sciencedirect.com
    Consumption of fish oil high-fat diet induces murine hair loss via epidermal fatty acid binding protein in skin macrophages
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    1. scibot 18 Dec 2022
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    sciencedirect.com/science/article/pii/S2211124722016928
  44. link.springer.com link.springer.com
    RAGE deficiency ameliorates autoimmune hepatitis involving inhibition of IL-6 production via suppressing protein Arid5a in mice
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      DOI: 10.1007/s10238-022-00960-8

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    link.springer.com/article/10.1007/s10238-022-00960-8
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    Vitamin B5 rewires Th17 cell metabolism via impeding PKM2 nuclear translocation
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    1. scibot 01 Dec 2022
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      DOI: 10.1016/j.celrep.2022.111741

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    sciencedirect.com/science/article/pii/S2211124722016199
  46. Nov 2022
  47. www.sciencedirect.com www.sciencedirect.com
    A tick C1q protein alters infectivity of the Lyme disease agent by modulating interferon γ
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    1. scibot 24 Nov 2022
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    sciencedirect.com/science/article/pii/S2211124722015479
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    FABP5 controls macrophage alternative activation and allergic asthma by selectively programming long-chain unsaturated fatty acid metabolism
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    sciencedirect.com/science/article/pii/S221112472201542X
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    Re-purposing the pro-senescence properties of doxorubicin to introduce immunotherapy in breast cancer brain metastasis
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    sciencedirect.com/science/article/pii/S2666379122003809
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    Identification and characterization of innate lymphoid cells generated from pluripotent stem cells
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    sciencedirect.com/science/article/pii/S2211124722014309
  51. Oct 2022
  52. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The proprotein convertase furin regulates the development of thymic epithelial cells to ensure central immune tolerance
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      DOI: 10.1016/j.isci.2022.105233

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    ncbi.nlm.nih.gov/pmc/articles/PMC9579486/
  53. Sep 2022
  54. www.sciencedirect.com www.sciencedirect.com
    cis interaction of CD153 with TCR/CD3 is crucial for the pathogenic activation of senescence-associated T cells
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    sciencedirect.com/science/article/pii/S2211124722012050
  55. Aug 2022
  56. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Quantitative Increase in T Regulatory Cells Enhances Bone Remodeling in Osteogenesis Imperfecta
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      DOI: 10.1016/j.isci.2022.104818

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    ncbi.nlm.nih.gov/pmc/articles/PMC9400089/
  57. Jul 2022
  58. www.sciencedirect.com www.sciencedirect.com
    Large-scale multiplexed mosaic CRISPR perturbation in the whole organism
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      DOI: 10.1016/j.cell.2022.06.039

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    sciencedirect.com/science/article/pii/S0092867422007917
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    B cell-mediated regulatory mechanisms control tumor-promoting intestinal inflammation
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    sciencedirect.com/science/article/pii/S2211124722008452
  60. Jun 2022
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    Antigen bivalency of antigen-presenting cell-targeted vaccines increases B cell responses
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    sciencedirect.com/science/article/pii/S2211124722006763
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    Carbon monoxide activates PERK-regulated autophagy to induce immunometabolic reprogramming and boost anti-tumor T cell function
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      DOI: 10.1158/0008-5472.CAN-21-3155

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  63. Apr 2022
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    ILC precursors differentiate into metabolically distinct ILC1-like cells during Mycobacterium tuberculosis infection
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  65. Mar 2022
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    PTIP governs NAD+ metabolism by regulating CD38 expression to drive macrophage inflammation
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    Lactylation-driven METTL3-mediated RNA m6A modification promotes immunosuppression of tumor-infiltrating myeloid cells
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    Mechanosensitive ACKR4 scavenges CCR7 chemokines to facilitate T cell de-adhesion and passive transport by flow in inflamed afferent lymphatics
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  70. Dec 2021
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    A defective viral genome strategy elicits broad protective immunity against respiratory viruses
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  72. Nov 2021
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    Insular cortex neurons encode and retrieve specific immune responses
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    6-Phosphogluconate dehydrogenase (6PGD), a key checkpoint in reprogramming of regulatory T cells metabolism and function
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  75. Oct 2021
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    Differential m6A RNA landscapes across hematopoiesis reveal a role for IGF2BP2 in preserving hematopoietic stem cell function
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    Candida albicans elicits protective allergic responses via platelet mediated T helper 2 and T helper 17 cell polarization
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    Aspartate availability limits hematopoietic stem cell function during hematopoietic regeneration
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    Hsf1 promotes hematopoietic stem cell fitness and proteostasis in response to ex vivo culture stress and aging
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  84. Jul 2021
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    Endogenous Retrovirus Envelope as a Tumor-Associated Immunotherapeutic Target in Murine Osteosarcoma
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  87. May 2021
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    Aging-dependent mitochondrial dysfunction mediated by ceramide signaling inhibits antitumor T cell response
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    Optogenetic activation of local colonic sympathetic innervations attenuates colitis by limiting immune cell extravasation
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  90. Apr 2021
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    Mitochondrial Oxidative Damage Underlies Regulatory T Cell Defects in Autoimmunity
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  92. Mar 2021
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    Blockade of 6-phosphogluconate dehydrogenase generates CD8+ effector T cells with enhanced anti-tumor function
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  94. Sep 2020
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    The PD-1 Pathway Regulates Development and Function of Memory CD8+ T Cells following Respiratory Viral Infection
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    Leukemogenic Chromatin Alterations Promote AML Leukemia Stem Cells via a KDM4C-ALKBH5-AXL Signaling Axis
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    Complement Signals Determine Opposite Effects of B Cells in Chemotherapy-Induced Immunity
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    Formation of Human Neuroblastoma in Mouse-Human Neural Crest Chimeras
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  99. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    CD49a Regulates Cutaneous Resident Memory CD8+ T Cell Persistence and Response
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  100. Jan 2020
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    Defining Genetic Variation in Widely Used Congenic and Backcrossed Mouse Models Reveals Varied Regulation of Genes Important for Immune Responses
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    Polyamines Control eIF5A Hypusination, TFEB Translation, and Autophagy to Reverse B Cell Senescence
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    Cathepsin G Inhibition by Serpinb1 and Serpinb6 Prevents Programmed Necrosis in Neutrophils and Monocytes and Reduces GSDMD-Driven Inflammation
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    Smad7 Controls Immunoregulatory PDL2/1-PD1 Signaling in Intestinal Inflammation and Autoimmunity
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  107. Nov 2018
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    Th9 Cells Represent a Unique Subset of CD4+ T Cells Endowed with the Ability to Eradicate Advanced Tumors
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    Dietary Fiber Confers Protection against Flu by Shaping Ly6c− Patrolling Monocyte Hematopoiesis and CD8+ T Cell Metabolism
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    CD150high Bone Marrow Tregs Maintain Hematopoietic Stem Cell Quiescence and Immune Privilege via Adenosine
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    Initiation of Antiviral B Cell Immunity Relies on Innate Signals from Spatially Positioned NKT Cells
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    CD38-NAD+Axis Regulates Immunotherapeutic Anti-Tumor T Cell Response
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  114. Nov 2017
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    CTCF-Mediated Enhancer-Promoter Interaction Is a Critical Regulator of Cell-to-Cell Variation of Gene Expression
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    Autophagy-Dependent Generation of Free Fatty Acids Is Critical for Normal Neutrophil Differentiation
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    The DNA Methylcytosine Dioxygenase Tet2 Sustains Immunosuppressive Function of Tumor-Infiltrating Myeloid Cells to Promote Melanoma Progression
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    Long-term intravital imaging of the multicolor-coded tumor microenvironment during combination immunotherapy
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