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Spatiotemporal analysis reveals distinct inflammatory programs underlying chronic colitis

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1. scibot 07 May 2026
  
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  DOI: 10.1016/j.immuni.2026.04.005
  
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sciencedirect.com/science/article/pii/S1074761326001676
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Tissue-specific tolerance mechanisms and lymph node co-drainage shape T cell immunity in the upper digestive system and pancreatic cancer progression

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1. scibot 07 May 2026
  
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  DOI: 10.1016/j.celrep.2026.117324
  
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sciencedirect.com/science/article/pii/S221112472600402X
May 2026
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VSIG4 restricts hepatocellular carcinoma control by suppressing tumor-specific CD8+ T cell immunity in the tumor microenvironment

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1. scibot 05 May 2026
  
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  DOI: 10.1158/2326-6066.CIR-25-0836
  
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aacrjournals.org/cancerimmunolres/article/14/5/718/784454/VSIG4-Restricts-Hepatocellular-Carcinoma-Control
Mar 2026
54.241.53.176 54.241.53.176

1-s2.0-S1525001626002078-main-html.html

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1. scibot 26 Mar 2026
  
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  DOI: 10.1016/j.ymthe.2026.03.022
  
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54.241.53.176/1bbab35eaaabafd7256ed6ca4414216ab2c9bdd6/1-s2.0-S1525001626002078-main-html.html
54.241.53.176 54.241.53.176

1-s2.0-S2589004226008114-main-html.html

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1. scibot 24 Mar 2026
  
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54.241.53.176/93767e79123191e1a85980095271822e8b705dad/1-s2.0-S2589004226008114-main-html.html
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Nasal RNA-scaffold-protein vaccine protects mice from human H5N1 clade 2.3.4.4b virus lethal infection and safeguards against vaccine-unmatched viruses

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1. scibot 24 Mar 2026
  
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  DOI: 10.1016/j.ebiom.2026.106228
  
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sciencedirect.com/science/article/pii/S2352396426001106
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Long-term vagus nerve stimulation synergized with rapamycin elicits neuroimmune modulation to prolong skin allograft survival

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1. scibot 21 Mar 2026
  
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  DOI: 10.1016/j.isci.2026.115189
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12995910/
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Enhanced HIF-1α cooperation by a human RORγt mutant potentiates Th17 pathogenicity

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1. scibot 20 Mar 2026
  
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  DOI: 10.1016/j.celrep.2026.117123
  
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sciencedirect.com/science/article/pii/S2211124726002019
Feb 2026
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Activation status of astrocytes drives the MS/NMOSD therapeutic paradox: Insights from IFNAR1 signaling

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1. scibot 05 Feb 2026
  
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  DOI: 10.1016/j.celrep.2025.116913
  
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sciencedirect.com/science/article/pii/S2211124725016857
Nov 2025
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GM-CSF and specific type 2 cytokines induce CD103+ and CD301b+ cell states in cDC1s and cDC2s

1
1. scibot 29 Nov 2025
  
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  DOI: 10.1016/j.celrep.2025.116589
  
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sciencedirect.com:5037/science/article/pii/S2211124725013610
54.241.53.176 54.241.53.176

2025.11.06.687030v2.full-html.html

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1. scibot 13 Nov 2025
  
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  DOI: 10.1101/2025.11.06.687030
  
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54.241.53.176/61ff3c01c4fabc7d4036cd8525cf0aefcb431dbf/2025.11.06.687030v2.full-html.html
Aug 2025
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Tumor-resident probiotic Clostridium butyricum improves aPD-1 efficacy in colorectal cancer models by inhibiting IL-6-mediated immunosuppression

1
1. scibot 08 Aug 2025
  
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  DOI: 10.1016/j.ccell.2025.07.012
  
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sciencedirect.com/science/article/pii/S1535610825003186
Jul 2025
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Augment proteasome inhibitor efficacy activates CD8+ T cell-mediated antitumor immunity in breast cancer

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1. scibot 02 Jul 2025
  
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  DOI: 10.1016/j.xcrm.2025.102211
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12281435/
Jun 2025
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Targeting the CD40 costimulatory receptor to improve virotherapy efficacy in diffuse midline gliomas

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1. scibot 28 Jun 2025
  
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  DOI: 10.1016/j.xcrm.2025.102204
  
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sciencedirect.com/science/article/pii/S2666379125002770
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An organoid co-culture model for probing systemic anti-tumor immunity in lung cancer

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1. scibot 13 Jun 2025
  
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  DOI: 10.1016/j.stem.2025.05.011
  
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sciencedirect.com/science/article/pii/S1934590925001912
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KMT2D coordinates antiviral CD4+ T cell responses through opposing effects on T follicular helper and cytotoxic gene expression

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1. scibot 03 Jun 2025
  
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  DOI: 10.1016/j.celrep.2025.115775
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12302258/
May 2025
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Bacteroides fragilis promotes chemoresistance in colorectal cancer, and its elimination by phage VA7 restores chemosensitivity

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1. scibot 31 May 2025
  
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  DOI: 10.1016/j.chom.2025.05.004
  
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sciencedirect.com/science/article/pii/S1931312825001830
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Serotonin transporter inhibits antitumor immunity through regulating the intratumoral serotonin axis

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1. scibot 22 May 2025
  
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  DOI: 10.1016/j.cell.2025.04.032
  
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sciencedirect.com/science/article/pii/S0092867425005021
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Myeloid-lineage-specific membrane protein LRRC25 suppresses immunity in solid tumor and is a potential cancer immunotherapy checkpoint target

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1. scibot 16 May 2025
  
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  DOI: 10.1016/j.celrep.2025.115631
  
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sciencedirect.com/science/article/pii/S2211124725004024
Mar 2025
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Metallophilic marginal zone macrophages cross-prime CD8+ T cell-mediated protective immunity against blood-borne tumors

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1. scibot 29 Mar 2025
  
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  DOI: 10.1016/j.immuni.2025.02.027
  
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sciencedirect.com/science/article/pii/S1074761325000949
Jan 2025
52.53.155.43 52.53.155.43

1-s2.0-S2589004225000641-main-html.html

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1. scibot 23 Jan 2025
  
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  DOI: 10.1016/j.isci.2025.111804
  
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52.53.155.43/bb0038ac4731f895cea6a9b8553ebcc516f55d21/1-s2.0-S2589004225000641-main-html.html
Aug 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Galectin-3 induces pathogenic immunosuppressive macrophages through interaction with TREM2 in lung cancer

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1. scibot 22 Aug 2024
  
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  DOI: 10.1186/s13046-024-03124-6
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11321020/
May 2024
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Intratumoral delivery of the chitin-derived C100 adjuvant promotes robust STING, IFNAR, and CD8+ T cell-dependent anti-tumor immunity

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1. scibot 10 May 2024
  
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  DOI: 10.1016/j.xcrm.2024.101560
  
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sciencedirect.com/science/article/pii/S2666379124002520
Apr 2024
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The microbiota and T cells non-genetically modulate inherited phenotypes transgenerationally

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1. scibot 05 Apr 2024
  
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  DOI: 10.1016/j.celrep.2024.114029
  
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2. scibot 05 Apr 2024
  
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  DOI: 10.1016/j.celrep.2024.114029
  
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sciencedirect.com/science/article/pii/S2211124724003577
Mar 2024
www.nature.com www.nature.com

IKK2 controls the inflammatory potential of tissue-resident regulatory T cells in a murine gain of function model

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1. scibot 26 Mar 2024
  
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  DOI: 10.1038/s41467-024-45870-3
  
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nature.com/articles/s41467-024-45870-3
Feb 2024
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RORα is required for expansion and memory maintenance of ILC1s via a lymph node-liver axis

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1. scibot 16 Feb 2024
  
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  DOI: 10.1016/j.celrep.2024.113786
  
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  DOI: 10.1016/j.celrep.2024.113786
  
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sciencedirect.com/science/article/pii/S2211124724001141
Jan 2024
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Skin microbe-dependent TSLP-ILC2 priming axis in early life is co-opted in allergic inflammation

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1. scibot 11 Jan 2024
  
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  DOI: 10.1016/j.chom.2023.12.006
  
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sciencedirect.com/science/article/pii/S1931312823005012
Dec 2023
journals.asm.org journals.asm.org

Circular RNA vaccines with long-term lymph node-targeting delivery stability after lyophilization induce potent and persistent immune responses

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1. scibot 15 Dec 2023
  
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  DOI: 10.1128/mbio.01775-23
  
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journals.asm.org/doi/10.1128/mbio.01775-23
Nov 2023
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Stress-induced β cell early senescence confers protection against type 1 diabetes

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1. scibot 17 Nov 2023
  
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  DOI: 10.1016/j.cmet.2023.10.014
  
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sciencedirect.com/science/article/pii/S1550413123003832
Oct 2023
www.tandfonline.com www.tandfonline.com

A single immunization with core-shell structured lipopolyplex mRNA vaccine against rabies induces potent humoral immunity in mice and dogs

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1. scibot 28 Oct 2023
  
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  DOI: 10.1080/22221751.2023.2270081
  
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tandfonline.com/doi/full/10.1080/22221751.2023.2270081
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TIM-3 blockade in diffuse intrinsic pontine glioma models promotes tumor regression and antitumor immune memory

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1. scibot 13 Oct 2023
  
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  DOI: 10.1016/j.ccell.2023.09.001
  
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sciencedirect.com/science/article/pii/S1535610823003185
Aug 2023
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Endogenous CCL21-Ser deficiency reduces B16–F10 melanoma growth by enhanced antitumor immunity

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1. scibot 23 Aug 2023
  
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  DOI: 10.1016/j.heliyon.2023.e19215
  
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sciencedirect.com/science/article/pii/S240584402306423X
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Loss of CD4+ T cell-intrinsic arginase 1 accelerates Th1 response kinetics and reduces lung pathology during influenza infection

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1. scibot 12 Aug 2023
  
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  RRID:AB_312713
  
  DOI: 10.1016/j.immuni.2023.07.014
  
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sciencedirect.com/science/article/pii/S1074761323003278
Jul 2023
onlinelibrary.wiley.com onlinelibrary.wiley.com

CCL21-Ser expression in melanoma cells recruits CCR7+ naïve T cells to tumor tissues and promotes tumor growth

1
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  DOI: 10.1111/cas.15902
  
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Enhanced bypass of PD-L1 translation reduces the therapeutic response to mTOR kinase inhibitors

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Vaccine-boosted CAR T crosstalk with host immunity to reject tumors with antigen heterogeneity

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May 2023
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cis-B7:CD28 interactions at invaginated synaptic membranes provide CD28 co-stimulation and promote CD8+ T cell function and anti-tumor immunity

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Apr 2023
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An immune cell lipid atlas reveals the basis of susceptibility to ferroptosis

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Mar 2023
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Arresting microbiome development limits immune system maturation and resistance to infection in mice

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CEACAM1 is a direct SOX10 target and inhibits melanoma immune infiltration and stemness

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Coxsackievirus B infections are common in Cystic Fibrosis and experimental evidence supports protection by vaccination

1
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Proinflammatory signaling in islet β cells propagates invasion of pathogenic immune cells in autoimmune diabetes

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PGE2-EP2/EP4 signaling elicits immunosuppression by driving the mregDC-Treg axis in inflammatory tumor microenvironment

1
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May 2022
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Corneal tissue-resident memory T cells form a unique immune compartment at the ocular surface

1
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PDGFRα-induced stromal maturation is required to restrain postnatal intestinal epithelial stemness and promote defense mechanisms

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Zinc finger protein Zfp335 controls early T-cell development and survival through β-selection-dependent and -independent mechanisms

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  DOI: 10.7554/eLife.75508
  
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Jan 2022
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Fine-tuning of MEK signaling is pivotal for limiting B and T cell activation

1
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Nov 2021
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Reprogramming NK cells and macrophages via combined antibody and cytokine therapy primes tumors for elimination by checkpoint blockade

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Epithelial-myeloid exchange of MHC class II constrains immunity and microbiota composition

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Activating a collaborative innate-adaptive immune response to control metastasis

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sciencedirect.com/science/article/pii/S1535610821004451
Aug 2021
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Butyrate Protects Mice from Clostridium difficile-Induced Colitis through an HIF-1-Dependent Mechanism

1
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Untitled document

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Untitled document

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  DOI: 10.1016/j.molcel.2018.10.034
  
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Untitled document

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  DOI: 10.1016/j.immuni.2018.10.008
  
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sciencedirect.com/science/article/pii/S1074761318304497
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PARP7 negatively regulates the type I interferon response in cancer cells and its inhibition triggers antitumor immunity

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A safe and effective mucosal RSV vaccine in mice consisting of RSV phosphoprotein and flagellin variant

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Resident memory T cells in tumor-distant tissues fortify against metastasis formation

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sciencedirect.com/science/article/pii/S2211124721004575
Apr 2021
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Follicular regulatory T cells produce neuritin to regulate B cells

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  DOI: 10.1016/j.cell.2021.02.027
  
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Single-cell chromatin accessibility landscape identifies tissue repair program in human regulatory T cells

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Protein S-nitrosylation regulates proteostasis and viability of hematopoietic stem cell during regeneration

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sciencedirect.com/science/article/pii/S2211124721002369
Feb 2021
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Depletion of Toll-Like Receptor-9 Attenuates Renal Tubulointerstitial Fibrosis After Ischemia-Reperfusion Injury

1
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  DOI: 10.3389/fcell.2021.641527
  
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frontiersin.org/article/10.3389/fcell.2021.641527/full
Jan 2021
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Stearoyl-CoA Desaturase-Mediated Monounsaturated Fatty Acid Availability Supports Humoral Immunity

1
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  DOI: 10.1016/j.celrep.2020.108601
  
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ncbi.nlm.nih.gov/pmc/articles/PMC7839063/
Nov 2020
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Antagonistic Inflammatory Phenotypes Dictate Tumor Fate and Response to Immune Checkpoint Blockade

1
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sciencedirect.com/science/article/pii/S1074761320304611
Sep 2020
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Beta Cell Dedifferentiation Induced by IRE1α Deletion Prevents Type 1 Diabetes

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A Thermostable mRNA Vaccine against COVID-19

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  DOI: 10.1016/j.cell.2020.07.024
  
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ncbi.nlm.nih.gov/pmc/articles/PMC7377714/
Jan 2020
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Epithelial NOTCH Signaling Rewires the Tumor Microenvironment of Colorectal Cancer to Drive Poor-Prognosis Subtypes and Metastasis

1
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ncbi.nlm.nih.gov/pmc/articles/PMC6853173/
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Untitled document

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  DOI: 10.1016/j.cell.2018.12.012
  
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sciencedirect.com/science/article/pii/S009286741831626X
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  RRID:AB_312713
  
  DOI: 10.1016/j.celrep.2018.11.083
  
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sciencedirect.com/science/article/pii/S2211124718318746
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Untitled document

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1. scibot 13 Jan 2020
  
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  RRID:AB_312713
  
  DOI: 10.1016/j.immuni.2018.12.024
  
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sciencedirect.com/science/article/pii/S1074761318305727
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Logic-Gated ROR1 Chimeric Antigen Receptor Expression Rescues T Cell-Mediated Toxicity to Normal Tissues and Enables Selective Tumor Targeting

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1. scibot 13 Jan 2020
  
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  RRID:AB_312713
  
  DOI: 10.1016/j.ccell.2019.02.003
  
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sciencedirect.com/science/article/pii/S1535610819300984
Nov 2018
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

CRIg, a tissue-resident macrophage specific immune checkpoint molecule, promotes immunological tolerance in NOD mice, via a dual role in effector and regulatory T cells

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1. scibot 05 Nov 2018
  
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ncbi.nlm.nih.gov/pmc/articles/PMC5728720/

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