100 Matching Annotations
  1. Jun 2024
  2. www.sciencedirect.com www.sciencedirect.com
    Glycoengineering-based anti-PD-1-iRGD peptide conjugate boosts antitumor efficacy through T cell engagement
    1
    1. scibot 06 Jun 2024
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      DOI: 10.1016/j.xcrm.2024.101590

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    sciencedirect.com/science/article/pii/S2666379124002829
  3. May 2024
  4. www.sciencedirect.com www.sciencedirect.com
    Mast cells control lung type 2 inflammation via prostaglandin E2-driven soluble ST2
    1
    1. scibot 31 May 2024
      RRID:AB_312745

      DOI: 10.1016/j.immuni.2024.05.003

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    sciencedirect.com/science/article/pii/S1074761324002541
  5. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    PABPC1L induces IDO1 to promote tryptophan metabolism and immune suppression in renal cell carcinoma
    1
    1. scibot 17 May 2024
      RRID:AB_312745

      DOI: 10.1158/0008-5472.CAN-23-2521

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    ncbi.nlm.nih.gov/pmc/articles/PMC11094425/
  6. Mar 2024
  7. www.sciencedirect.com www.sciencedirect.com
    Derivation of functional thymic epithelial organoid lines from adult murine thymus
    1
    1. scibot 29 Mar 2024
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      DOI: 10.1016/j.celrep.2024.114019

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    sciencedirect.com/science/article/pii/S2211124724003474
  8. www.sciencedirect.com www.sciencedirect.com
    Hippo-signaling-controlled MHC class I antigen processing and presentation pathway potentiates antitumor immunity
    1
    1. scibot 27 Mar 2024
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      DOI: 10.1016/j.celrep.2024.114003

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    sciencedirect.com/science/article/pii/S2211124724003310
  9. 52.53.155.43 52.53.155.43
    Low-dose Decitabine enhances the efficacy of viral cancer vaccines for immunotherapy.
    1
    1. scibot 12 Mar 2024
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      DOI: 10.1016/j.omton.2024.200766

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    52.53.155.43/8c6eb3b4d009a4f511a3160975bf106d9641ff9c/1-s2.0-S2950329924000080-main-html.html
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    Differentiation route determines the functional outputs of adult megakaryopoiesis
    1
    1. scibot 06 Mar 2024
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      DOI: 10.1016/j.immuni.2024.02.006

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    sciencedirect.com/science/article/pii/S1074761324000827
  11. Feb 2024
  12. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Revealing splenectomy-driven microRNA hsa-7b-5p’s role in pancreatic cancer progression
    1
    1. scibot 16 Feb 2024
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      DOI: 10.1016/j.isci.2024.109045

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    ncbi.nlm.nih.gov/pmc/articles/PMC10864800/
  13. www.sciencedirect.com www.sciencedirect.com
    Dietary elaidic acid boosts tumoral antigen presentation and cancer immunity via ACSL5
    1
    1. scibot 14 Feb 2024
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      DOI: 10.1016/j.cmet.2024.01.012

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    sciencedirect.com/science/article/pii/S1550413124000123
  14. Jan 2024
  15. dx.doi.org dx.doi.org
    Formate supplementation enhances anti-tumor CD8+ T cell fitness and efficacy of PD-1 blockade
    1
    1. scibot 11 Jan 2024
      RRID:AB_312745

      DOI: 10.1158/2159-8290.CD-22-1301

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    dx.doi.org/10.1158/2159-8290.CD-22-1301
  16. www.sciencedirect.com www.sciencedirect.com
    Deciphering the metabolic heterogeneity of hematopoietic stem cells with single-cell resolution
    1
    1. scibot 06 Jan 2024
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      DOI: 10.1016/j.cmet.2023.12.005

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    sciencedirect.com/science/article/pii/S1550413123004564
  17. Dec 2023
  18. www.sciencedirect.com www.sciencedirect.com
    Synthetically mannosylated antigens induce antigen-specific humoral tolerance and reduce anti-drug antibody responses to immunogenic biologics
    1
    1. scibot 22 Dec 2023
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      DOI: 10.1016/j.xcrm.2023.101345

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    sciencedirect.com/science/article/pii/S2666379123005621
  19. www.sciencedirect.com www.sciencedirect.com
    MHC class II regulation of CD8+ T cell tolerance and implications in autoimmunity and cancer immunotherapy
    1
    1. scibot 01 Dec 2023
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      DOI: 10.1016/j.celrep.2023.113452

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    sciencedirect.com/science/article/pii/S221112472301464X
  20. 52.53.155.43 52.53.155.43
    cd-22-1301-html.html
    1
    1. scibot 01 Dec 2023
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      DOI: 10.1158/2159-8290.cd-22-1301

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    52.53.155.43/ed2c7eab61775ee4a9efbdfa91d6b4b18a13354a/cd-22-1301-html.html
  21. Nov 2023
  22. www.sciencedirect.com www.sciencedirect.com
    Isolation of single cells from individual mouse ovaries for flow cytometry and functional analysis
    1
    1. scibot 18 Nov 2023
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      DOI: 10.1016/j.xpro.2023.102710

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    sciencedirect.com/science/article/pii/S2666166723006779
  23. www.sciencedirect.com www.sciencedirect.com
    PD-L1-mediated immune evasion in triple-negative breast cancer is linked to the loss of ZNF652
    1
    1. scibot 02 Nov 2023
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      DOI: 10.1016/j.celrep.2023.113343

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    sciencedirect.com/science/article/pii/S2211124723013554
  24. Oct 2023
  25. www.sciencedirect.com www.sciencedirect.com
    Stress regulates Alzheimer’s disease progression via selective enrichment of CD8+ T cells
    1
    1. scibot 27 Oct 2023
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      DOI: 10.1016/j.celrep.2023.113313

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    sciencedirect.com/science/article/pii/S2211124723013256
  26. www.embopress.org www.embopress.org
    Cytotoxic T lymphocytes require transcription for infiltration but not target cell lysis
    1
    1. scibot 21 Oct 2023
      RRID:AB_312745

      DOI: 10.15252/embr.202357653

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    embopress.org/doi/10.15252/embr.202357653
  27. www.science.org www.science.org
    Lymph node–resident dendritic cells drive TH2 cell development involving MARCH1
    1
    1. scibot 17 Oct 2023
      RRID:AB_312745

      DOI: 10.1126/sciimmunol.abh0707

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    science.org/doi/10.1126/sciimmunol.abh0707
  28. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    CD38 regulates ovarian function and fecundity via NAD+ metabolism
    1
    1. scibot 14 Oct 2023
      RRID:AB_312745

      DOI: 10.1016/j.isci.2023.107949

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    ncbi.nlm.nih.gov/pmc/articles/PMC10562803/
  29. www.sciencedirect.com www.sciencedirect.com
    Renal tubular epithelial cells are constitutive non-cognate stimulators of resident T cells
    1
    1. scibot 13 Oct 2023
      RRID:AB_312745

      DOI: 10.1016/j.celrep.2023.113210

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    sciencedirect.com/science/article/pii/S2211124723012226
  30. Sep 2023
  31. www.sciencedirect.com www.sciencedirect.com
    Hematopoietic cell-derived IL-15 supports NK cell development in scattered and clustered localization within the bone marrow
    1
    1. scibot 30 Sep 2023
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      DOI: 10.1016/j.celrep.2023.113127

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    sciencedirect.com/science/article/pii/S2211124723011397
  32. Aug 2023
  33. 52.53.155.43 52.53.155.43
    Targeting TCF19 sensitizes MSI endometrial cancer to anti-PD-1 therapy by alleviating CD8+ T cell exhaustion via TRIM14-IFN-β axis
    2
    1. scibot 17 Aug 2023
      RRID:AB_312745

      DOI: 10.1016/j.celrep.2023.112944

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      DOI: 10.1016/j.celrep.2023.112944

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    52.53.155.43/f1aa479ee50c1426738d478d555cd8c52a91c49e/PIIS2211124723009555-html.html
  34. Jul 2023
  35. www.sciencedirect.com www.sciencedirect.com
    Liver sinusoidal endothelial cells orchestrate NK cell recruitment and activation in acute inflammatory liver injury
    1
    1. scibot 21 Jul 2023
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      DOI: 10.1016/j.celrep.2023.112836

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    sciencedirect.com/science/article/pii/S2211124723008471
  36. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    CCR4 and CCR7 differentially regulate thymocyte localization with distinct outcomes for central tolerance
    1
    1. scibot 08 Jul 2023
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      DOI: 10.7554/eLife.80443

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    ncbi.nlm.nih.gov/pmc/articles/PMC10325719/
  37. May 2023
  38. www.sciencedirect.com www.sciencedirect.com
    CCL19+ dendritic cells potentiate clinical benefit of anti-PD-(L)1 immunotherapy in triple-negative breast cancer
    1
    1. scibot 18 May 2023
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      DOI: 10.1016/j.medj.2023.04.008

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    sciencedirect.com/science/article/pii/S266663402300140X
  39. Apr 2023
  40. www.sciencedirect.com www.sciencedirect.com
    NK cell-derived extracellular granzyme B drives epithelial ulceration during HSV-2 genital infection
    1
    1. scibot 20 Apr 2023
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      DOI: 10.1016/j.celrep.2023.112410

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    sciencedirect.com/science/article/pii/S2211124723004217
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    Harnessing matrix stiffness to engineer a bone marrow niche for hematopoietic stem cell rejuvenation
    1
    1. scibot 07 Apr 2023
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      DOI: 10.1016/j.stem.2023.03.005

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    sciencedirect.com/science/article/pii/S1934590923000760
  42. www.sciencedirect.com www.sciencedirect.com
    Spleen fibroblastic reticular cell-derived acetylcholine promotes lipid metabolism to drive autoreactive B cell responses
    1
    1. scibot 06 Apr 2023
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      DOI: 10.1016/j.cmet.2023.03.010

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    sciencedirect.com/science/article/pii/S1550413123000888
  43. Mar 2023
  44. europepmc.org europepmc.org
    Saturated fatty acids dampen the immunogenicity of cancer by suppressing STING
    1
    1. scibot 28 Mar 2023
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      DOI: 10.1016/j.celrep.2023.112303

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    europepmc.org/article/med/36952341
  45. www.sciencedirect.com www.sciencedirect.com
    Tumor PD-L1 engages myeloid PD-1 to suppress type I interferon to impair cytotoxic T lymphocyte recruitment
    1
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      DOI: 10.1016/j.ccell.2023.02.005

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    sciencedirect.com/science/article/pii/S1535610823000338
  46. Feb 2023
  47. www.sciencedirect.com www.sciencedirect.com
    PHGDH-mediated endothelial metabolism drives glioblastoma resistance to chimeric antigen receptor T cell immunotherapy
    1
    1. scibot 23 Feb 2023
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    sciencedirect.com/science/article/pii/S1550413123000104
  48. Jan 2023
  49. www.sciencedirect.com www.sciencedirect.com
    Decoding m6A RNA methylome identifies PRMT6-regulated lipid transport promoting AML stem cell maintenance
    1
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      DOI: 10.1016/j.stem.2022.12.003

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    sciencedirect.com/science/article/pii/S1934590922004878
  50. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Lymphatic PD-L1 Expression Restricts Tumor-Specific CD8+ T-cell Responses
    1
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      DOI: 10.1158/0008-5472.CAN-21-0633

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    ncbi.nlm.nih.gov/pmc/articles/PMC9398148/
  51. www.sciencedirect.com www.sciencedirect.com
    Bispecific PD1-IL2v and anti-PD-L1 break tumor immunity resistance by enhancing stem-like tumor-reactive CD8+ T cells and reprogramming macrophages
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    sciencedirect.com/science/article/pii/S1074761322006422
  52. www.sciencedirect.com www.sciencedirect.com
    NKG2D signaling shifts the balance of CD8 T cells from single cytokine- to polycytokine-producing effector cells
    1
    1. scibot 12 Jan 2023
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      DOI: 10.1016/j.molimm.2022.12.013

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    sciencedirect.com/science/article/pii/S016158902200503X
  53. Dec 2022
  54. www.sciencedirect.com www.sciencedirect.com
    Recruited monocytes/macrophages drive pulmonary neutrophilic inflammation and irreversible lung tissue remodeling in cystic fibrosis
    1
    1. scibot 18 Dec 2022
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      DOI: 10.1016/j.celrep.2022.111797

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    sciencedirect.com/science/article/pii/S2211124722016850
  55. Nov 2022
  56. www.sciencedirect.com www.sciencedirect.com
    Chronic type I interferon signaling promotes lipid-peroxidation-driven terminal CD8+ T cell exhaustion and curtails anti-PD-1 efficacy
    1
    1. scibot 16 Nov 2022
      RRID:AB_312745

      DOI: 10.1016/j.celrep.2022.111647

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    sciencedirect.com/science/article/pii/S2211124722015182
  57. Oct 2022
  58. www.sciencedirect.com www.sciencedirect.com
    Ferroptosis heterogeneity in triple-negative breast cancer reveals an innovative immunotherapy combination strategy
    1
    1. scibot 20 Oct 2022
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      DOI: 10.1016/j.cmet.2022.09.021

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  59. Sep 2022
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    Cancer cell autophagy, reprogrammed macrophages, and remodeled vasculature in glioblastoma triggers tumor immunity
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    Balance between immunoregulatory B cells and plasma cells drives pancreatic tumor immunity
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  62. Aug 2022
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    Integrated single-cell transcriptomic analyses reveal that GPNMB-high macrophages promote PN-MES transition and impede T cell activation in GBM
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    Phospholipid metabolites of the gut microbiota promote hypoxia-induced intestinal injury via CD1d-dependent γδ T cells
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  65. Jul 2022
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    Increased Expression of Multiple Co-Inhibitory Molecules on Malaria-Induced CD8+ T Cells Are Associated With Increased Function Instead of Exhaustion
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    B cell-mediated regulatory mechanisms control tumor-promoting intestinal inflammation
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  68. Jun 2022
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    Carbon monoxide activates PERK-regulated autophagy to induce immunometabolic reprogramming and boost anti-tumor T cell function
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  70. May 2022
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    Protective activity of mRNA vaccines against ancestral and variant SARS-CoV-2 strains
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  72. Apr 2022
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    ILC precursors differentiate into metabolically distinct ILC1-like cells during Mycobacterium tuberculosis infection
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    Lymph node–resident dendritic cells drive TH2 cell development involving MARCH1
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    Aedes aegypti sialokinin facilitates mosquito blood feeding and modulates host immunity and vascular biology
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    Type 1 conventional dendritic cells maintain and guide the differentiation of precursors of exhausted T cells in distinct cellular niches
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  77. Mar 2022
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    PTIP governs NAD+ metabolism by regulating CD38 expression to drive macrophage inflammation
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    Mucus sialylation determines intestinal host-commensal homeostasis
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    Zinc finger protein Zfp335 controls early T-cell development and survival through β-selection-dependent and -independent mechanisms
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  81. Feb 2022
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    A FBXO7/EYA2-SCFFBXW7 axis promotes AXL-mediated maintenance of mesenchymal and immune evasion phenotypes of cancer cells
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    Mechanosensitive ACKR4 scavenges CCR7 chemokines to facilitate T cell de-adhesion and passive transport by flow in inflamed afferent lymphatics
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  84. Jan 2022
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    Magnesium sensing via LFA-1 regulates CD8+ T cell effector function
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  86. Dec 2021
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    Neoantigen-driven B cell and CD4 T follicular helper cell collaboration promotes anti-tumor CD8 T cell responses
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  88. Nov 2021
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    The cell-surface 5′-nucleotidase CD73 defines a functional T memory cell subset that declines with age
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    6-Phosphogluconate dehydrogenase (6PGD), a key checkpoint in reprogramming of regulatory T cells metabolism and function
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  91. Oct 2021
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    Interleukin-10 induces interferon-γ-dependent emergency myelopoiesis
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    Multilayer omics analysis reveals a non-classical retinoic acid signaling axis that regulates hematopoietic stem cell identity
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    Differential m6A RNA landscapes across hematopoiesis reveal a role for IGF2BP2 in preserving hematopoietic stem cell function
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  95. Sep 2021
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    Mutations in the adenosine deaminase ADAR1 that prevent endogenous Z-RNA binding induce Aicardi-Goutières-syndrome-like encephalopathy
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    Activating a collaborative innate-adaptive immune response to control metastasis
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  98. Aug 2021
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  101. Jul 2021
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  104. May 2021
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    Suppressive neutrophils require PIM1 for metabolic fitness and survival during chronic viral infection
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    T cell self-reactivity during thymic development dictates the timing of positive selection
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    Discrete limbal epithelial stem cell populations mediate corneal homeostasis and wound healing
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    Single-Cell Analysis of Neonatal HSC Ontogeny Reveals Gradual and Uncoordinated Transcriptional Reprogramming that Begins before Birth
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    Aging-dependent mitochondrial dysfunction mediated by ceramide signaling inhibits antitumor T cell response
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  110. Apr 2021
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    NAD+ Metabolism Maintains Inducible PD-L1 Expression to Drive Tumor Immune Evasion
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    UTX promotes CD8+ T cell-mediated antiviral defenses but reduces T cell durability
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    CD169+ lymph node macrophages have protective functions in mouse breast cancer metastasis
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    Single-cell chromatin accessibility landscape identifies tissue repair program in human regulatory T cells
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  115. www.sciencedirect.com www.sciencedirect.com
    Protein S-nitrosylation regulates proteostasis and viability of hematopoietic stem cell during regeneration
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      RRID:AB_312745

      DOI: 10.1016/j.celrep.2021.108922

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    sciencedirect.com/science/article/pii/S2211124721002369
  116. Mar 2021
  117. www.sciencedirect.com www.sciencedirect.com
    Blockade of 6-phosphogluconate dehydrogenase generates CD8+ effector T cells with enhanced anti-tumor function
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      RRID:AB_312745

      DOI: 10.1016/j.celrep.2021.108831

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    sciencedirect.com/science/article/pii/S2211124721001455
  118. Feb 2021
  119. www.sciencedirect.com www.sciencedirect.com
    FBXO44 promotes DNA replication-coupled repetitive element silencing in cancer cells
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      RRID:AB_312745

      DOI: 10.1016/j.cell.2020.11.042

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    sciencedirect.com/science/article/pii/S0092867420316147
  120. www.sciencedirect.com www.sciencedirect.com
    Kmt2c mutations enhance HSC self-renewal capacity and convey a selective advantage after chemotherapy
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      RRID:AB_312745

      DOI: 10.1016/j.celrep.2021.108751

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    sciencedirect.com/science/article/pii/S2211124721000644
  121. www.sciencedirect.com www.sciencedirect.com
    Dynamic adoption of anergy by antigen-exhausted CD4+ T cells
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      RRID:AB_312745

      DOI: 10.1016/j.celrep.2021.108748

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    sciencedirect.com/science/article/pii/S2211124721000619
  122. Oct 2020
  123. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Critical role of WNK1 in MYC-dependent early mouse thymocyte development
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      RRID:AB_312745

      DOI: 10.7554/eLife.56934

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    ncbi.nlm.nih.gov/pmc/articles/PMC7591260/
  124. Sep 2020
  125. www.sciencedirect.com www.sciencedirect.com
    Cancer-Specific Loss of p53 Leads to a Modulation of Myeloid and T Cell Responses
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      RRID:AB_312745

      DOI: 10.1016/j.celrep.2019.12.028

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  126. www.sciencedirect.com www.sciencedirect.com
    Leukemogenic Chromatin Alterations Promote AML Leukemia Stem Cells via a KDM4C-ALKBH5-AXL Signaling Axis
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      RRID:AB_312745

      DOI: 10.1016/j.stem.2020.04.001

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    sciencedirect.com/science/article/pii/S1934590920301405
  127. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A Thermostable mRNA Vaccine against COVID-19
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      DOI: 10.1016/j.cell.2020.07.024

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    ncbi.nlm.nih.gov/pmc/articles/PMC7377714/
  128. www.cell.com www.cell.com
    Dynamics of the Coreceptor-LCK Interactions during T Cell Development Shape the Self-Reactivity of Peripheral CD4 and CD8 T Cells
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      RRID:AB_312745

      DOI: 10.1016/j.celrep.2020.01.008

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    cell.com/cell-reports/abstract/S2211-1247(20)30017-6
  129. Jan 2020
  130. www.sciencedirect.com www.sciencedirect.com
    Systematic Immunotherapy Target Discovery Using Genome-Scale In Vivo CRISPR Screens in CD8 T Cells
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      RRID:AB_312745

      DOI: 10.1016/j.cell.2019.07.044

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  131. www.sciencedirect.com www.sciencedirect.com
    PD-1 Signaling Promotes Control of Chronic Viral Infection by Restricting Type-I-Interferon-Mediated Tissue Damage
    1
    1. scibot 13 Jan 2020
      RRID:AB_312745

      DOI: 10.1016/j.celrep.2019.10.092

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    sciencedirect.com/science/article/pii/S2211124719314147
  132. www.sciencedirect.com www.sciencedirect.com
    Salmonella-Driven Polarization of Granuloma Macrophages Antagonizes TNF-Mediated Pathogen Restriction during Persistent Infection
    1
    1. scibot 13 Jan 2020
      RRID:AB_312745

      DOI: 10.1016/j.chom.2019.11.011

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    sciencedirect.com/science/article/pii/S1931312819305931
  133. www.sciencedirect.com www.sciencedirect.com
    Pro-Survival Lipid Sphingosine-1-Phosphate Metabolically Programs T Cells to Limit Anti-tumor Activity
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    1. scibot 13 Jan 2020
      RRID:AB_312745

      DOI: 10.1016/j.celrep.2019.07.044

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    sciencedirect.com/science/article/pii/S2211124719309416
  134. www.sciencedirect.com www.sciencedirect.com
    Untitled document
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      RRID:AB_312745

      DOI: 10.1016/j.immuni.2019.01.021

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    sciencedirect.com/science/article/pii/S1074761319300445
  135. Nov 2018
  136. www.sciencedirect.com www.sciencedirect.com
    Daily Onset of Light and Darkness Differentially Controls Hematopoietic Stem Cell Differentiation and Maintenance
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      RRID:AB_312745

      Curator: @Jmenke

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    sciencedirect.com/science/article/pii/S1934590918303874
  137. www.sciencedirect.com www.sciencedirect.com
    Interleukin-10 Directly Inhibits CD8+ T Cell Function by Enhancing N-Glycan Branching to Decrease Antigen Sensitivity
    1
    1. scibot 05 Nov 2018
      RRID:AB_312745

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    sciencedirect.com/science/article/pii/S1074761318300062
  138. www.sciencedirect.com www.sciencedirect.com
    CD38-NAD+Axis Regulates Immunotherapeutic Anti-Tumor T Cell Response
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    1. scibot 05 Nov 2018
      RRID:AB_312745

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    sciencedirect.com/science/article/pii/S1550413117306186
  139. www.sciencedirect.com www.sciencedirect.com
    Epigenetic Therapy Ties MYC Depletion to Reversing Immune Evasion and Treating Lung Cancer
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    1. scibot 05 Nov 2018
      RRID:AB_312745

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    sciencedirect.com/science/article/pii/S0092867417312448
  140. Nov 2017
  141. www.sciencedirect.com www.sciencedirect.com
    CXCL14 Acts as a Specific Carrier of CpG DNA into Dendritic Cells and Activates Toll-like Receptor 9-mediated Adaptive Immunity
    1
    1. scibot 08 Nov 2017
      RRID:AB_312745

      Curator: @Jmenke

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    sciencedirect.com/science/article/pii/S2352396417303651