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    Preclinical study and phase II trial of adapting low-dose radiotherapy to immunotherapy in small cell lung cancer
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    Metabolic reprogramming and dysregulated IL-17 production impairs CD4 T cell function post sepsis
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  4. Jul 2024
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  6. Jun 2024
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    Blockage of L2HGDH-mediated S-2HG catabolism orchestrates macrophage polarization to elicit antitumor immunity
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  8. May 2024
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    Intratumoral delivery of the chitin-derived C100 adjuvant promotes robust STING, IFNAR, and CD8+ T cell-dependent anti-tumor immunity
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  10. Apr 2024
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    Targeting branched N-glycans and fucosylation sensitizes ovarian tumors to immune checkpoint blockade
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  12. Mar 2024
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    Nanodrug-bacteria conjugates-mediated oncogenic collagen depletion enhances immune checkpoint blockade therapy against pancreatic cancer
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    Differentiation route determines the functional outputs of adult megakaryopoiesis
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    Multimodal immune phenotyping reveals microbial-T cell interactions that shape pancreatic cancer
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  16. Feb 2024
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    Inhibition of PRL2 upregulates PTEN and attenuates tumor growth in Tp53-deficient sarcoma and lymphoma mouse models
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    aacrjournals.org/cancerrescommun/article/4/1/5/732220/Inhibition-of-PRL2-Upregulates-PTEN-and-Attenuates
  18. Jan 2024
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    Inhibition of PRL2 upregulates PTEN and attenuates tumor growth in Tp53-deficient sarcoma and lymphoma mouse models
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  20. Dec 2023
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    Dihydroartemisinin inhibits the development of colorectal cancer by GSK-3β/TCF7/MMP9 pathway and synergies with capecitabine
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  22. Nov 2023
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    Keratinocyte FABP5-VCP complex mediates recruitment of neutrophils in psoriasis
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    An essential role for miR-15/16 in Treg suppression and restriction of proliferation
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  25. Oct 2023
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    High NEK2 expression in myeloid progenitors suppresses T cell immunity in multiple myeloma
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  27. Sep 2023
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    Hematopoietic cell-derived IL-15 supports NK cell development in scattered and clustered localization within the bone marrow
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    Enzyme-mediated depletion of methylthioadenosine restores T cell function in MTAP-deficient tumors and reverses immunotherapy resistance
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  30. Aug 2023
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    A CSF-1R-blocking antibody/IL-10 fusion protein increases anti-tumor immunity by effectuating tumor-resident CD8+ T cells
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  32. Jul 2023
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    Enhanced bypass of PD-L1 translation reduces the therapeutic response to mTOR kinase inhibitors
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  34. Jun 2023
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    Coupled deglycosylation-ubiquitination cascade in regulating PD-1 degradation by MDM2
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    Polycomb repressive complex 1.1 coordinates homeostatic and emergency myelopoiesis
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    Systematic dissection of coordinated stromal remodeling identifies Sox10+ glial cells as a therapeutic target in myelofibrosis
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  38. May 2023
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    YTHDF2 inhibition potentiates radiotherapy antitumor efficacy
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  40. Apr 2023
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    Cooperative super-enhancer inactivation caused by heterozygous loss of CREBBP and KMT2D skews B cell fate decisions and yields T cell-depleted lymphomas
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  42. Feb 2023
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    KDM5A Inhibits Antitumor Immune Responses Through Downregulation of the Antigen-Presentation Pathway in Ovarian Cancer
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  44. Jan 2023
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    The loss of epithelial Smad4 drives immune evasion via CXCL1 while displaying vulnerability to combinatorial immunotherapy in gastric cancer
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    Opioid-induced fragile-like regulatory T cells contribute to withdrawal
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    Targeting Menin disrupts the KMT2A/B and polycomb balance to paradoxically activate bivalent genes
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    Diurnal Expression of PD-1 on Tumor-Associated Macrophages Underlies the Dosing Time-Dependent Antitumor Effects of the PD-1/PD-L1 Inhibitor BMS-1 in B16/BL6 Melanoma-Bearing Mice
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    CD8+ T cell-intrinsic IL-6 signaling promotes resistance to anti-PD-L1 immunotherapy
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  50. Dec 2022
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    Consumption of fish oil high-fat diet induces murine hair loss via epidermal fatty acid binding protein in skin macrophages
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    Across-cancer immune responses induced by nanovaccines or microvaccines to prevent different cancers and cancer metastasis
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    ncbi.nlm.nih.gov/pmc/articles/PMC9682363/
  53. Sep 2022
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    Inhibition of the CtBP complex and FBXO11 enhances MHC class II expression and anti-cancer immune responses
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  55. Jul 2022
  56. 52.53.155.43 52.53.155.43
    cir-22-0088-html.html
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    PDGFRβ+ cells play a dual role as hematopoietic precursors and niche cells during mouse ontogeny
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    sciencedirect.com/science/article/pii/S2211124722009202
  58. Jun 2022
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    Envelope virus-mimetic nanovaccines by hybridizing bioengineered cell membranes with bacterial vesicles
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    sciencedirect.com/science/article/pii/S2589004222007611
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    PGE2-EP2/EP4 signaling elicits immunosuppression by driving the mregDC-Treg axis in inflammatory tumor microenvironment
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    The SETDB1–TRIM28 complex suppresses antitumor immunity
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  62. Mar 2022
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    Zinc finger protein Zfp335 controls early T-cell development and survival through β-selection-dependent and -independent mechanisms
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  64. Feb 2022
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    An oncogenic enhancer encodes selective selenium dependency in AML
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  66. Jan 2022
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    Magnesium sensing via LFA-1 regulates CD8+ T cell effector function
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    Histone deacetylase 3 contributes to the antiviral innate immunity of macrophages by interacting with FOXK1 to regulate STAT1/2 transcription
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  69. Dec 2021
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    Genome-wide fitness gene identification reveals Roquin as a potent suppressor of CD8 T cell expansion and anti-tumor immunity
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  73. Nov 2021
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    m6A mRNA methylation-directed myeloid cell activation controls progression of NAFLD and obesity
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  76. Sep 2021
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  81. Jul 2021
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    NKG2A Blockade Potentiates CD8 T Cell Immunity Induced by Cancer Vaccines
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  83. Jun 2021
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    Targeted delivery of regulatory macrophages to lymph nodes interferes with T cell priming by preventing the formation of stable immune synapses
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    Resistance to lethal ectromelia virus infection requires Type I interferon receptor in natural killer cells and monocytes but not in adaptive immune or parenchymal cells
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  86. May 2021
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    Single-cell analysis by mass cytometry reveals metabolic states of early-activated CD8+ T cells during the primary immune response
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    Impaired Kupffer Cell Self-Renewal Alters the Liver Response to Lipid Overload during Non-alcoholic Steatohepatitis
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  89. Apr 2021
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    Ultra-low Dose Aerosol Infection of Mice with Mycobacterium tuberculosis More Closely Models Human Tuberculosis
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    Increased stem cell proliferation in atherosclerosis accelerates clonal hematopoiesis
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  92. Feb 2021
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    Smectite promotes probiotic biofilm formation in the gut for cancer immunotherapy
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  94. Dec 2020
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    Ascorbic Acid Promotes Plasma Cell Differentiation through Enhancing TET2/3-Mediated DNA Demethylation
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  96. Nov 2020
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    Antagonistic Inflammatory Phenotypes Dictate Tumor Fate and Response to Immune Checkpoint Blockade
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  98. Oct 2020
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  100. Sep 2020
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    Fibroblast-Derived STC-1 Modulates Tumor-Associated Macrophages and Lung Adenocarcinoma Development
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    Profiling of patients with glioma reveals the dominant immunosuppressive axis is refractory to immune function restoration
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    Single-Cell RNA Sequencing Reveals a Dynamic Stromal Niche That Supports Tumor Growth
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    Quantitative analysis of how Myc controls T cell proteomes and metabolic pathways during T cell activation
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    Neutrophil Caspase-11 Is Essential to Defend against a Cytosol-Invasive Bacterium
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  106. Jan 2020
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    An Evolutionarily Conserved Function of Polycomb Silences the MHC Class I Antigen Presentation Pathway and Enables Immune Evasion in Cancer
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    Differential Roles of the mTOR-STAT3 Signaling in Dermal γδ T Cell Effector Function in Skin Inflammation
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    Junctional Adhesion Molecule 2 Represents a Subset of Hematopoietic Stem Cells with Enhanced Potential for T Lymphopoiesis
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  111. Nov 2018
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    Non-canonical NF-κB Antagonizes STING Sensor-Mediated DNA Sensing in Radiotherapy
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    Th9 Cells Represent a Unique Subset of CD4+ T Cells Endowed with the Ability to Eradicate Advanced Tumors
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    Tumor-Repopulating Cells Induce PD-1 Expression in CD8+ T Cells by Transferring Kynurenine and AhR Activation
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    KLRG1+ Effector CD8+ T Cells Lose KLRG1, Differentiate into All Memory T Cell Lineages, and Convey Enhanced Protective Immunity
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    CRIg, a tissue-resident macrophage specific immune checkpoint molecule, promotes immunological tolerance in NOD mice, via a dual role in effector and regulatory T cells
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    Crucial role for T cell-intrinsic IL-18R-MyD88 signaling in cognate immune response to intracellular parasite infection.
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