105 Matching Annotations
  1. Sep 2024
  2. www.sciencedirect.com www.sciencedirect.com
    Cathepsin G Inhibition by Serpinb1 and Serpinb6 Prevents Programmed Necrosis in Neutrophils and Monocytes and Reduces GSDMD-Driven Inflammation
    1
    1. scibot 25 Sep 2024
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    sciencedirect.com/science/article/pii/S2211124719306941
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    Intercellular nanotube-mediated mitochondrial transfer enhances T cell metabolic fitness and antitumor efficacy
    1
    1. scibot 17 Sep 2024
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      DOI: 10.1016/j.cell.2024.08.029

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    sciencedirect.com/science/article/pii/S0092867424009565
  4. Aug 2024
  5. www.cell.com www.cell.com
    Endocytosis Inhibition in Humans to Improve Responses to ADCC-Mediating Antibodies
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    1. scibot 22 Aug 2024
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      DOI: 10.1016/j.cell.2020.02.019

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    cell.com/cell/fulltext/S0092-8674(20)30163-X
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    LAG-3 and PD-1 synergize on CD8+ T cells to drive T cell exhaustion and hinder autocrine IFN-γ-dependent anti-tumor immunity
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    1. scibot 20 Aug 2024
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      DOI: 10.1016/j.cell.2024.07.016

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    sciencedirect.com/science/article/pii/S0092867424007761
  7. www.science.org www.science.org
    Machine learning predictions of T cell antigen specificity from intracellular calcium dynamics
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    1. scibot 02 Aug 2024
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      DOI: 10.1126/sciadv.adk2298

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    science.org/doi/10.1126/sciadv.adk2298
  8. Jul 2024
  9. www.sciencedirect.com www.sciencedirect.com
    Innate immune memory after brain injury drives inflammatory cardiac dysfunction
    1
    1. scibot 25 Jul 2024
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      DOI: 10.1016/j.cell.2024.06.028

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    sciencedirect.com/science/article/pii/S0092867424007025
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    Sugar and arginine facilitate oral tolerance by ensuring the functionality of tolerogenic immune cell subsets in the intestine
    1
    1. scibot 11 Jul 2024
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    sciencedirect.com/science/article/pii/S2211124724008192
  11. www.cell.com www.cell.com
    GRP75-dependent mitochondria-ER contacts ensure cell survival during early mouse thymocyte development
    1
    1. scibot 11 Jul 2024
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    cell.com/developmental-cell/abstract/S1534-5807(24)00385-X
  12. May 2024
  13. www.sciencedirect.com www.sciencedirect.com
    Distinct roles of TREM2 in central nervous system cancers and peripheral cancers
    1
    1. scibot 24 May 2024
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    sciencedirect.com/science/article/pii/S1535610824001624
  14. Apr 2024
  15. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Time of Day and Circadian Disruption Influence Host Response and Parasite Growth in a Mouse Model of Cerebral Malaria
    1
    1. scibot 30 Apr 2024
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      DOI: 10.1016/j.isci.2024.109684

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    ncbi.nlm.nih.gov/pmc/articles/PMC11053314/
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    Macrophage-coated tumor cluster aggravates hepatoma invasion and immunotherapy resistance via generating local immune deprivation
    1
    1. scibot 16 Apr 2024
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    sciencedirect.com/science/article/pii/S2666379124001745
  17. Mar 2024
  18. www.sciencedirect.com www.sciencedirect.com
    Microbial metabolite enhances immunotherapy efficacy by modulating T cell stemness in pan-cancer
    1
    1. scibot 15 Mar 2024
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    sciencedirect.com/science/article/pii/S0092867424002241
  19. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Machine learning predictions of T cell antigen specificity from intracellular calcium dynamics
    1
    1. scibot 09 Mar 2024
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      DOI: 10.1126/sciadv.adk2298

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    ncbi.nlm.nih.gov/pmc/articles/PMC10917351/
  20. Feb 2024
  21. www.sciencedirect.com www.sciencedirect.com
    ZEB1 shapes AML immunological niches, suppressing CD8 T cell activity while fostering Th17 cell expansion
    1
    1. scibot 16 Feb 2024
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      DOI: 10.1016/j.celrep.2024.113794

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    sciencedirect.com/science/article/pii/S2211124724001220
  22. www.sciencedirect.com www.sciencedirect.com
    Itaconate impairs immune control of Plasmodium by enhancing mtDNA-mediated PD-L1 expression in monocyte-derived dendritic cells
    1
    1. scibot 08 Feb 2024
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    sciencedirect.com/science/article/pii/S1550413124000081
  23. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Mice Generated with Induced Pluripotent Stem Cells Derived from Mucosal-Associated Invariant T Cells
    1
    1. scibot 01 Feb 2024
      RRID:AB_312753

      DOI: 10.3390/biomedicines12010137

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    ncbi.nlm.nih.gov/pmc/articles/PMC10813358/
  24. Jan 2024
  25. www.sciencedirect.com www.sciencedirect.com
    Bispecific dendritic-T cell engager potentiates anti-tumor immunity
    1
    1. scibot 19 Jan 2024
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      DOI: 10.1016/j.cell.2023.12.011

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    sciencedirect.com/science/article/pii/S0092867423013430
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    Response to Bruton’s tyrosine kinase inhibitors in aggressive lymphomas linked to chronic selective autophagy
    1
    1. scibot 12 Jan 2024
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      DOI: 10.1016/j.ccell.2023.12.019

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    sciencedirect.com/science/article/pii/S1535610823004476
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    Interferon-stimulated neutrophils as a predictor of immunotherapy response
    1
    1. scibot 09 Jan 2024
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      DOI: 10.1016/j.ccell.2023.12.005

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    sciencedirect.com/science/article/pii/S1535610823004336
  28. Dec 2023
  29. www.sciencedirect.com www.sciencedirect.com
    MHC class II regulation of CD8+ T cell tolerance and implications in autoimmunity and cancer immunotherapy
    1
    1. scibot 01 Dec 2023
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      DOI: 10.1016/j.celrep.2023.113452

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    sciencedirect.com/science/article/pii/S221112472301464X
  30. Nov 2023
  31. www.sciencedirect.com www.sciencedirect.com
    S. aureus drives itch and scratch-induced skin damage through a V8 protease-PAR1 axis
    1
    1. scibot 28 Nov 2023
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      DOI: 10.1016/j.cell.2023.10.019

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    sciencedirect.com/science/article/pii/S0092867423011649
  32. Oct 2023
  33. www.embopress.org www.embopress.org
    IL-27 produced during acute malaria infection regulates Plasmodium-specific memory CD4+ T cells
    1
    1. scibot 20 Oct 2023
      RRID:AB_312753

      DOI: 10.15252/emmm.202317713

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    embopress.org/doi/10.15252/emmm.202317713
  34. Aug 2023
  35. 52.53.155.43 52.53.155.43
    Membrane-localized neoantigens predict the efficacy of cancer immunotherapy
    2
    1. scibot 12 Aug 2023
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    52.53.155.43/9f1a09025b86686c62561e67323b0c82e4153e7b/PIIS2666379123002987-html.html
  36. Jul 2023
  37. www.sciencedirect.com www.sciencedirect.com
    QUAS-R: An SLC1A5-mediated glutamine uptake assay with single-cell resolution reveals metabolic heterogeneity with immune populations
    1
    1. scibot 21 Jul 2023
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      DOI: 10.1016/j.celrep.2023.112828

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    sciencedirect.com/science/article/pii/S2211124723008392
  38. www.sciencedirect.com www.sciencedirect.com
    Rebalancing liver-infiltrating CCR3+ and CD206+ monocytes improves diet-induced NAFLD
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    1. scibot 08 Jul 2023
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    sciencedirect.com/science/article/pii/S2211124723007647
  39. Jun 2023
  40. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Polycomb repressive complex 1.1 coordinates homeostatic and emergency myelopoiesis
    1
    1. scibot 24 Jun 2023
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      DOI: 10.7554/eLife.83004

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    ncbi.nlm.nih.gov/pmc/articles/PMC10287155/
  41. May 2023
  42. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Chronic psychological stress promotes breast cancer pre-metastatic niche formation by mobilizing splenic MDSCs via TAM/CXCL1 signaling
    1
    1. scibot 23 May 2023
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      DOI: 10.1186/s13046-023-02696-z

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    ncbi.nlm.nih.gov/pmc/articles/PMC10199643/
  43. Apr 2023
  44. www.sciencedirect.com www.sciencedirect.com
    SIRT2 inhibition by AGK2 enhances mycobacteria-specific stem cell memory responses by modulating beta-catenin and glycolysis
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    1. scibot 27 Apr 2023
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      DOI: 10.1016/j.isci.2023.106644

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    sciencedirect.com/science/article/pii/S2589004223007216
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    Gut dysbiosis promotes the breakdown of oral tolerance mediated through dysfunction of mucosal dendritic cells
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    1. scibot 27 Apr 2023
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      DOI: 10.1016/j.celrep.2023.112431

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    sciencedirect.com/science/article/pii/S2211124723004424
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    The gut microbiota promotes distal tissue regeneration via RORγ+ regulatory T cell emissaries
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    1. scibot 20 Apr 2023
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      DOI: 10.1016/j.immuni.2023.01.033

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    sciencedirect.com/science/article/pii/S1074761323000456
  47. onlinelibrary.wiley.com onlinelibrary.wiley.com
    ERK Inhibition Promotes Engraftment of Allografts by Reprogramming T-Cell Metabolism
    1
    1. scibot 06 Apr 2023
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      DOI: 10.1002/advs.202206768

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    onlinelibrary.wiley.com/doi/10.1002/advs.202206768
  48. Mar 2023
  49. www.sciencedirect.com www.sciencedirect.com
    Stepwise activities of mSWI/SNF family chromatin remodeling complexes direct T cell activation and exhaustion
    1
    1. scibot 23 Mar 2023
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    sciencedirect.com/science/article/pii/S1097276523001533
  50. europepmc.org europepmc.org
    ILC3s restrict the dissemination of intestinal bacteria to safeguard liver regeneration after surgery
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    europepmc.org/article/med/36933213
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    Endoplasmic reticulum stress in the intestinal epithelium initiates purine metabolite synthesis and promotes Th17 cell differentiation in the gut
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    sciencedirect.com/science/article/pii/S1074761323000924
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    Single-cell RNA sequencing reveals immunosuppressive myeloid cell diversity during malignant progression in a murine model of glioma
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    sciencedirect.com/science/article/pii/S2211124723002085
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    Adhesion analysis via a tumor vasculature-like microfluidic device identifies CD8+ T cells with enhanced tumor homing to improve cell therapy
    1
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    sciencedirect.com/science/article/pii/S2211124723001869
  54. www.sciencedirect.com www.sciencedirect.com
    Apoptotic cell fragments locally activate tingible body macrophages in the germinal center
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  55. Feb 2023
  56. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The altering cellular components and function in tumor microenvironment during remissive and relapsed stages of anti-CD19 CAR T-cell treated lymphoma mice
    1
    1. scibot 10 Feb 2023
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      DOI: 10.3389/fimmu.2023.1101769

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    ncbi.nlm.nih.gov/pmc/articles/PMC9905118/
  57. www.sciencedirect.com www.sciencedirect.com
    IDH2 and TET2 mutations synergize to modulate T Follicular Helper cell functional interactionwith the AITL microenvironment
    1
    1. scibot 03 Feb 2023
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      DOI: 10.1016/j.ccell.2023.01.003

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    sciencedirect.com/science/article/pii/S153561082300003X
  58. Jan 2023
  59. www.sciencedirect.com www.sciencedirect.com
    The aryl hydrocarbon receptor cell intrinsically promotes resident memory CD8+ T cell differentiation and function
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    1. scibot 19 Jan 2023
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      DOI: 10.1016/j.celrep.2022.111963

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    Lymphatic PD-L1 Expression Restricts Tumor-Specific CD8+ T-cell Responses
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  61. Dec 2022
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    RAGE deficiency ameliorates autoimmune hepatitis involving inhibition of IL-6 production via suppressing protein Arid5a in mice
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  63. Nov 2022
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    Obesity enhances antiviral immunity in the genital mucosa through a microbiota-mediated effect on γδ T cells
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    Isolating and targeting a highly active, stochastic dendritic cell subpopulation for improved immune responses
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  67. Oct 2022
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    PD-1/PD-L1 blockade abrogates a dysfunctional innate-adaptive immune axis in critical β-coronavirus disease
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    PD-1/PD-L1 blockade abrogates a dysfunctional innate-adaptive immune axis in critical β-coronavirus disease
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  70. Sep 2022
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    Increased glucose metabolism in TAMs fuels O-GlcNAcylation of lysosomal Cathepsin B to promote cancer metastasis and chemoresistance
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    ATF3 and CH25H regulate effector trogocytosis and anti-tumor activities of endogenous and immunotherapeutic cytotoxic T lymphocytes
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  73. Aug 2022
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    Faecalibaculum rodentium remodels retinoic acid signaling to govern eosinophil-dependent intestinal epithelial homeostasis
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  75. Jul 2022
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    mTORC1 signaling in antigen-presenting cells of the skin restrains CD8+ T cell priming
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  77. Jun 2022
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    Viral infection engenders bona fide and bystander subsets of lung-resident memory B cells through a permissive mechanism
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    Poroptosis: a form of cell death depending on plasma membrane nanopores formation
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  80. May 2022
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    Heterochronic parabiosis induces stem cell revitalization and systemic rejuvenation across aged tissues
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    Mycobacterium tuberculosis impedes CD40-dependent notch signaling to restrict Th17 polarization during infection
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  83. Apr 2022
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    Circular RNA vaccines against SARS-CoV-2 and emerging variants
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    Reprogramming and redifferentiation of mucosal-associated invariant T cells reveal tumor inhibitory activity
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  86. Feb 2022
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    Aire suppresses CTLA-4 expression from the thymic stroma to control autoimmunity
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  88. Dec 2021
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    Parity-induced changes to mammary epithelial cells control NKT cell expansion and mammary oncogenesis
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  90. Oct 2021
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    Rapid Serial Immunoprofiling of the Tumor Immune Microenvironment by Fine Needle Sampling
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  92. Sep 2021
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    Cognate recognition of microbial antigens defines constricted CD4+ T cell receptor repertoires in the inflamed colon
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    Dietary suppression of MHC class II expression in intestinal epithelial cells enhances intestinal tumorigenesis
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    Effector T cell responses unleashed by regulatory T cell ablation exacerbate oral squamous cell carcinoma
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    Activating a collaborative innate-adaptive immune response to control metastasis
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  97. Aug 2021
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    CXCR6 positions cytotoxic T cells to receive critical survival signals in the tumor microenvironment
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  102. Jul 2021
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    Checkpoint Blockade Immunotherapy Induces Dynamic Changes in PD-1−CD8+ Tumor-Infiltrating T Cells
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    Murine Norovirus Infection Induces TH1 Inflammatory Responses to Dietary Antigens
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    Mitochondrial Stress-Initiated Aberrant Activation of the NLRP3 Inflammasome Regulates the Functional Deterioration of Hematopoietic Stem Cell Aging
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  107. Jun 2021
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    Expansion of tumor-associated Treg cells upon disruption of a CTLA-4-dependent feedback loop
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  109. May 2021
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    Molecular tracking devices quantify antigen distribution and archiving in the murine lymph node
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    Endogenous Glucocorticoid Signaling Regulates CD8+ T Cell Differentiation and Development of Dysfunction in the Tumor Microenvironment
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  112. Apr 2021
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    Genetically engineered myeloid cells rebalance the core immune suppression program in metastasis
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    Single-cell chromatin accessibility landscape identifies tissue repair program in human regulatory T cells
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  115. Mar 2021
  116. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    IL-15/IL-15Rα Heterodimeric Complex as Cancer Immunotherapy in Murine Breast Cancer Models
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  117. Feb 2021
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    PD-L1 Reverse Signaling in Dermal Dendritic Cells Promotes Dendritic Cell Migration Required for Skin Immunity
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    Induction of Progenitor Exhausted Tissue-Resident Memory CD8+ T Cells Upon Salmonella Typhi Porins Adjuvant Immunization Correlates With Melanoma Control and Anti-PD-1 Immunotherapy Cooperation
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  120. Nov 2020
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    Induction of Progenitor Exhausted Tissue-Resident Memory CD8+ T Cells Upon Salmonella Typhi Porins Adjuvant Immunization Correlates With Melanoma Control and Anti-PD-1 Immunotherapy Cooperation
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  122. Oct 2020
  123. www.sciencedirect.com www.sciencedirect.com
    IL4I1 Is a Metabolic Immune Checkpoint that Activates the AHR and Promotes Tumor Progression
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  124. Sep 2020
  125. www.sciencedirect.com www.sciencedirect.com
    tagHi-C Reveals 3D Chromatin Architecture Dynamics during Mouse Hematopoiesis
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  126. www.sciencedirect.com www.sciencedirect.com
    Single-Cell RNA Sequencing Reveals a Dynamic Stromal Niche That Supports Tumor Growth
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  127. www.sciencedirect.com www.sciencedirect.com
    Diverse CD8 T Cell Responses to Viral Infection Revealed by the Collaborative Cross
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  128. www.cell.com www.cell.com
    Endocytosis Inhibition in Humans to Improve Responses to ADCC-Mediating Antibodies
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    Quantitative and Qualitative Analysis of Humoral Immunity Reveals Continued and Personalized Evolution in Chronic Viral Infection
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  130. www.sciencedirect.com www.sciencedirect.com
    PTPN2 Deficiency Enhances Programmed T Cell Expansion and Survival Capacity of Activated T Cells
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  131. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Squamous trans-differentiation of pancreatic cancer cells promotes stromal inflammation
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  132. Jan 2020
  133. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    The Transcription Factor Bhlhe40 Programs Mitochondrial Regulation of Resident CD8+ T Cell Fitness and Functionality
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  134. www.cell.com www.cell.com
    Podoplanin-Expressing Macrophages Promote Lymphangiogenesis and Lymphoinvasion in Breast Cancer
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  135. www.sciencedirect.com www.sciencedirect.com
    MicroRNA-142 Is Critical for the Homeostasis and Function of Type 1 Innate Lymphoid Cells
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    Maternal Antibodies Inhibit Neonatal and Infant Responses to Vaccination by Shaping the Early-Life B Cell Repertoire within Germinal Centers
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    Ligand-Blocking and Membrane-Proximal Domain Targeting Anti-OX40 Antibodies Mediate Potent T Cell-Stimulatory and Anti-Tumor Activity
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    TCF1 and LEF1 Control Treg Competitive Survival and Tfr Development to Prevent Autoimmune Diseases
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    Treg Cells Promote the SREBP1-Dependent Metabolic Fitness of Tumor-Promoting Macrophages via Repression of CD8+ T Cell-Derived Interferon-γ
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      DOI: 10.1016/j.immuni.2019.06.017

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  140. www.sciencedirect.com www.sciencedirect.com
    Requirement of Mitochondrial Transcription Factor A in Tissue-Resident Regulatory T Cell Maintenance and Function
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      DOI: 10.1016/j.celrep.2019.06.024

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  141. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    HIF-1α Is a Metabolic Switch between Glycolytic-Driven Migration and Oxidative Phosphorylation-Driven Immunosuppression of Tregs in Glioblastoma
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    1. scibot 13 Jan 2020
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      DOI: 10.1016/j.celrep.2019.03.029

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  142. www.sciencedirect.com www.sciencedirect.com
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      DOI: 10.1016/j.immuni.2019.01.001

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    sciencedirect.com/science/article/pii/S1074761319300019
  143. www.sciencedirect.com www.sciencedirect.com
    Negative Co-stimulation Constrains T Cell Differentiation by Imposing Boundaries on Possible Cell States
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      DOI: 10.1016/j.immuni.2019.03.004

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    sciencedirect.com/science/article/pii/S1074761319300949
  144. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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    ncbi.nlm.nih.gov/pmc/articles/PMC6461402/
  145. Nov 2018
  146. www-sciencedirect-com.ezproxy.is.ed.ac.uk www-sciencedirect-com.ezproxy.is.ed.ac.uk
    CD8+ T Cell Priming in Established Chronic Viral Infection Preferentially Directs Differentiation of Memory-like Cells for Sustained Immunity
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  147. elifesciences.org elifesciences.org
    Glutathione de novo synthesis but not recycling process coordinates with glutamine catabolism to control redox homeostasis and directs murine T cell differentiation
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    elifesciences.org/articles/36158
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    KLRG1+ Effector CD8+ T Cells Lose KLRG1, Differentiate into All Memory T Cell Lineages, and Convey Enhanced Protective Immunity
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    sciencedirect.com/science/article/pii/S1074761318300918