89 Matching Annotations
  1. Nov 2024
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    Distinct RORγt-dependent Th17 immune responses are required for autoimmune pathogenesis and protection against bacterial infection
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    1. scibot 15 Nov 2024
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      DOI: 10.1016/j.celrep.2024.114951

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    sciencedirect.com/science/article/pii/S2211124724013020
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    DHDH-mediated D-xylose metabolism induces immune evasion in triple-negative breast cancer
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    1. scibot 11 Nov 2024
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      DOI: 10.1016/j.medj.2024.10.012

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    sciencedirect.com/science/article/pii/S2666634024004100
  4. Sep 2024
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    Application of dual Nr4a1-GFP Nr4a3-Tocky reporter mice to study T cell receptor signaling by flow cytometry
    1
    1. scibot 25 Sep 2024
      RRID:AB_312760

      DOI: 10.1016/j.xpro.2020.100284

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    sciencedirect.com/science/article/pii/S2666166720302719
  6. Aug 2024
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    CD38-NAD+Axis Regulates Immunotherapeutic Anti-Tumor T Cell Response
    1
    1. scibot 21 Aug 2024
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      DOI: 10.1016/j.cmet.2017.10.006

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    sciencedirect.com/science/article/pii/S1550413117306186
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    Nuclear HMGB1 is critical for CD8 T cell IFN-γ production and anti-tumor immunity
    1
    1. scibot 20 Aug 2024
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    sciencedirect.com/science/article/pii/S2211124724009203
  9. Jul 2024
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    Prenatal inflammation remodels lung immunity and function by programming ILC2 hyperactivation
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    1. scibot 20 Jul 2024
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    sciencedirect.com/science/article/pii/S2211124724006934
  11. Apr 2024
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    IFNα-induced BST2+ tumor-associated macrophages facilitate immunosuppression and tumor growth in pancreatic cancer by ERK-CXCL7 signaling
    1
    1. scibot 11 Apr 2024
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    sciencedirect.com/science/article/pii/S2211124724004169
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    Cbl-b mitigates the responsiveness of naive CD8+ T cells that experience extensive tonic T cell receptor signaling
    1
    1. scibot 02 Apr 2024
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      DOI: 10.1126/scisignal.adh0439

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  14. Mar 2024
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    Adipose stem cells control obesity-induced T cell infiltration into adipose tissue
    1
    1. scibot 19 Mar 2024
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    sciencedirect.com/science/article/pii/S2211124724002912
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    ARID1A orchestrates SWI/SNF-mediated sequential binding of transcription factors with ARID1A loss driving pre-memory B cell fate and lymphomagenesis
    1
    1. scibot 08 Mar 2024
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    sciencedirect.com/science/article/pii/S1535610824000540
  17. Feb 2024
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    Systemic inflammatory response syndrome triggered by blood-borne pathogens induces prolonged dendritic cell paralysis and immunosuppression
    1
    1. scibot 14 Feb 2024
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    sciencedirect.com/science/article/pii/S2211124724000822
  19. Jan 2024
  20. www.sciencedirect.com www.sciencedirect.com
    CpsA mediates infection of recruited lung myeloid cells by Mycobacterium tuberculosis
    1
    1. scibot 12 Jan 2024
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      DOI: 10.1016/j.celrep.2023.113607

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    sciencedirect.com/science/article/pii/S2211124723016194
  21. Nov 2023
  22. www.sciencedirect.com www.sciencedirect.com
    E3 ligase Trim35 inhibits LSD1 demethylase activity through K63-linked ubiquitination and enhances anti-tumor immunity in NSCLC
    1
    1. scibot 22 Nov 2023
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      DOI: 10.1016/j.celrep.2023.113477

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    sciencedirect.com/science/article/pii/S2211124723014894
  23. Oct 2023
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    Effector memory T cells induce innate inflammation by triggering DNA damage and a non-canonical STING pathway in dendritic cells
    1
    1. scibot 14 Oct 2023
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      DOI: 10.1016/j.celrep.2023.113180

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    sciencedirect.com/science/article/pii/S2211124723011920
  25. 52.53.155.43 52.53.155.43
    High-resolution mapping of cell-cycle dynamics during steady-state T-cell development and regeneration in vivo
    1
    1. scibot 13 Oct 2023
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      DOI: 10.1101/2023.06.14.544919

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    52.53.155.43/5adb9a7f13046637b8804b132dfb3fb0676830a9/2023.06.14.544919v1.full-html.html
  26. Sep 2023
  27. www.sciencedirect.com www.sciencedirect.com
    Interferon-g-dependent interactions between tissue-intrinsic γδ T cells and tissue-infiltrating CD8 T cells limit acute contact dermatitis
    1
    1. scibot 29 Sep 2023
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      DOI: 10.1016/j.jaci.2023.07.015

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    sciencedirect.com/science/article/pii/S0091674923009818
  28. Aug 2023
  29. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    An agonistic anti-signal regulatory protein α antibody for chronic inflammatory diseases
    1
    1. scibot 26 Aug 2023
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      DOI: 10.1016/j.xcrm.2023.101130

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    ncbi.nlm.nih.gov/pmc/articles/PMC10439247/
  30. 52.53.155.43 52.53.155.43
    Targeting TCF19 sensitizes MSI endometrial cancer to anti-PD-1 therapy by alleviating CD8+ T cell exhaustion via TRIM14-IFN-β axis
    2
    1. scibot 17 Aug 2023
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      DOI: 10.1016/j.celrep.2023.112944

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    2. scibot 11 Aug 2023
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      DOI: 10.1016/j.celrep.2023.112944

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    52.53.155.43/f1aa479ee50c1426738d478d555cd8c52a91c49e/PIIS2211124723009555-html.html
  31. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Synergism Between IL21 and Anti-PD-1 Combination Therapy is Underpinned by the Coordinated Reprogramming of the Immune Cellular Network in the Tumor Microenvironment
    1
    1. scibot 10 Aug 2023
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      DOI: 10.1158/2767-9764.CRC-23-0012

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    ncbi.nlm.nih.gov/pmc/articles/PMC10402650/
  32. Jul 2023
  33. www.sciencedirect.com www.sciencedirect.com
    A genetic method specifically delineates Th1-type Treg cells and their roles in tumor immunity
    1
    1. scibot 13 Jul 2023
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      DOI: 10.1016/j.celrep.2023.112813

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    sciencedirect.com/science/article/pii/S2211124723008240
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    Controlling genetic heterogeneity in gene-edited hematopoietic stem cells by single-cell expansion
    1
    1. scibot 04 Jul 2023
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      DOI: 10.1016/j.stem.2023.06.002

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    sciencedirect.com/science/article/pii/S1934590923002138
  35. Jun 2023
  36. www.sciencedirect.com www.sciencedirect.com
    METTL3-mediated m6A methylation orchestrates mRNA stability and dsRNA contents to equilibrate γδ T1 and γδ T17 cells
    1
    1. scibot 27 Jun 2023
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      DOI: 10.1016/j.celrep.2023.112684

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    sciencedirect.com/science/article/pii/S2211124723006952
  37. Apr 2023
  38. www.sciencedirect.com www.sciencedirect.com
    NK cell-derived extracellular granzyme B drives epithelial ulceration during HSV-2 genital infection
    1
    1. scibot 20 Apr 2023
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      DOI: 10.1016/j.celrep.2023.112410

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    sciencedirect.com/science/article/pii/S2211124723004217
  39. Feb 2023
  40. www.sciencedirect.com www.sciencedirect.com
    Interplay between liver and blood stages of Plasmodium infection dictates malaria severity via γδ T cells and IL-17-promoted stress erythropoiesis
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    1. scibot 23 Feb 2023
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      DOI: 10.1016/j.immuni.2023.01.031

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    sciencedirect.com/science/article/pii/S1074761323000432
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    DRAK2 contributes to type 1 diabetes by negatively regulating IL-2 sensitivity to alter regulatory T cell development
    1
    1. scibot 17 Feb 2023
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      DOI: 10.1016/j.celrep.2023.112106

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    sciencedirect.com/science/article/pii/S2211124723001171
  42. Jan 2023
  43. www.sciencedirect.com www.sciencedirect.com
    Tissue resident iNKT17 cells facilitate cancer cell extravasation in liver metastasis via interleukin-22
    1
    1. scibot 12 Jan 2023
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      DOI: 10.1016/j.immuni.2022.12.014

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    sciencedirect.com/science/article/pii/S1074761322006501
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    T cell-derived interleukin-22 drives the expression of CD155 by cancer cells to suppress NK cell function and promote metastasis
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    1. scibot 12 Jan 2023
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      DOI: 10.1016/j.immuni.2022.12.010

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    sciencedirect.com/science/article/pii/S107476132200646X
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    Bispecific PD1-IL2v and anti-PD-L1 break tumor immunity resistance by enhancing stem-like tumor-reactive CD8+ T cells and reprogramming macrophages
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    1. scibot 12 Jan 2023
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      DOI: 10.1016/j.immuni.2022.12.006

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    sciencedirect.com/science/article/pii/S1074761322006422
  46. Oct 2022
  47. www.sciencedirect.com www.sciencedirect.com
    Expansion of T memory stem cells with superior anti-tumor immunity by Urolithin A-induced mitophagy
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    1. scibot 20 Oct 2022
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      DOI: 10.1016/j.immuni.2022.09.014

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    sciencedirect.com/science/article/pii/S1074761322005088
  48. Jul 2022
  49. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    T-cell dysfunction upon expression of MYC with altered phosphorylation at Threonine 58 and Serine 62
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    1. scibot 12 Jul 2022
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      DOI: 10.1158/1541-7786.MCR-21-0560

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    ncbi.nlm.nih.gov/pmc/articles/PMC9262837/
  50. Jun 2022
  51. aacrjournals.org aacrjournals.org
    Carbon monoxide activates PERK-regulated autophagy to induce immunometabolic reprogramming and boost anti-tumor T cell function
    1
    1. scibot 01 Jun 2022
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      DOI: 10.1158/0008-5472.CAN-21-3155

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    aacrjournals.org/cancerres/article/82/10/1969/696318/Carbon-Monoxide-Activates-PERK-Regulated-Autophagy
  52. May 2022
  53. www.sciencedirect.com www.sciencedirect.com
    Targeted LC-MS/MS-based metabolomics and lipidomics on limited hematopoietic stem cell numbers
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      DOI: 10.1016/j.xpro.2022.101408

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    sciencedirect.com/science/article/pii/S266616672200288X
  54. www.sciencedirect.com www.sciencedirect.com
    WEE1 inhibition enhances the antitumor immune response to PD-L1 blockade by the concomitant activation of STING and STAT1 pathways in SCLC
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      DOI: 10.1016/j.celrep.2022.110814

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    sciencedirect.com/science/article/pii/S221112472200585X
  55. Apr 2022
  56. www.sciencedirect.com www.sciencedirect.com
    Binding of LAG-3 to stable peptide-MHC class II limits T cell function and suppresses autoimmunity and anti-cancer immunity
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    1. scibot 13 Apr 2022
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      DOI: 10.1016/j.immuni.2022.03.013

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    sciencedirect.com/science/article/pii/S1074761322001364
  57. Mar 2022
  58. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Zinc finger protein Zfp335 controls early T-cell development and survival through β-selection-dependent and -independent mechanisms
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    1. scibot 04 Mar 2022
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      DOI: 10.7554/eLife.75508

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    ncbi.nlm.nih.gov/pmc/articles/PMC8871394/
  59. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Thymocytes trigger self-antigen-controlling pathways in immature medullary thymic epithelial stages
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    1. scibot 03 Mar 2022
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      DOI: 10.7554/eLife.69982

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    ncbi.nlm.nih.gov/pmc/articles/PMC8860447/
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    Resurfaced ZIKV EDIII nanoparticle immunogens elicit neutralizing and protective responses in vivo
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      DOI: 10.1016/j.chembiol.2022.02.004

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    sciencedirect.com/science/article/pii/S245194562200085X
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    Interferon-γ promotes monocyte-mediated lung injury during influenza infection
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    1. scibot 02 Mar 2022
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      DOI: 10.1016/j.celrep.2022.110456

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    sciencedirect.com/science/article/pii/S2211124722001838
  62. Dec 2021
  63. www.sciencedirect.com www.sciencedirect.com
    Secreted osteopontin from CD4+ T cells limits acute graft-versus-host disease
    1
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    Stem-like intestinal Th17 cells give rise to pathogenic effector T cells during autoimmunity
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    A defective viral genome strategy elicits broad protective immunity against respiratory viruses
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  66. Nov 2021
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    The allergy mediator histamine confers resistanceto immunotherapy in cancer patients via activationof the macrophage histamine receptor H1
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    Liver X receptors regulate natural killer T cell population and antitumor activity in the liver of mice
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    Single-cell transcriptomics reveals opposing roles of Shp2 in Myc-driven liver tumor cells and microenvironment
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  70. Oct 2021
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    Interleukin-10 induces interferon-γ-dependent emergency myelopoiesis
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    Multilayer omics analysis reveals a non-classical retinoic acid signaling axis that regulates hematopoietic stem cell identity
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  73. Sep 2021
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    Disruption of the endopeptidase ADAM10-Notch signaling axis leads to skin dysbiosis and innate lymphoid cell-mediated hair follicle destruction
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  75. Aug 2021
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    Dysregulation of ILC3s unleashes progression and immunotherapy resistance in colon cancer
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  77. Jul 2021
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    Homeostatic apoptosis prevents competition-induced atrophy in follicular B cells
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    Endogenous Retrovirus Envelope as a Tumor-Associated Immunotherapeutic Target in Murine Osteosarcoma
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  82. Jun 2021
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    Protocol to establish a lung adenocarcinoma immunotherapy allograft mouse model with FACS and immunofluorescence-based analysis of tumor response
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  84. May 2021
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    Repression of endogenous retroviruses prevents antiviral immune response and is required for mammary gland development
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    Fate mapping analysis reveals a novel murine dermal migratory Langerhans-like cell population
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    Interferon-γ induces tumor resistance to anti-PD-1 immunotherapy by promoting YAP phase separation
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    Dectin-1 limits autoimmune neuroinflammation and promotes myeloid cell-astrocyte crosstalk via Card9-independent expression of Oncostatin M
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    Substance P Release by Sensory Neurons Triggers Dendritic Cell Migration and Initiates the Type-2 Immune Response to Allergens
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    Aging-dependent mitochondrial dysfunction mediated by ceramide signaling inhibits antitumor T cell response
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  91. pubs.acs.org pubs.acs.org
    Effects of Chlorpyrifos on Serine Hydrolase Activities, Lipid Mediators, and Immune Responses in Lungs of Neonatal and Adult Mice
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  92. Apr 2021
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    Metabolic-Pathway-Based Subtyping of Triple-Negative Breast Cancer Reveals Potential Therapeutic Targets
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    Ultra-low Dose Aerosol Infection of Mice with Mycobacterium tuberculosis More Closely Models Human Tuberculosis
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    Single-cell chromatin accessibility landscape identifies tissue repair program in human regulatory T cells
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  96. Dec 2020
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    Autophagy in T cells from aged donors is maintained by spermidine and correlates with function and vaccine responses
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  98. Nov 2020
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    Antagonistic Inflammatory Phenotypes Dictate Tumor Fate and Response to Immune Checkpoint Blockade
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  101. Oct 2020
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    Critical role of WNK1 in MYC-dependent early mouse thymocyte development
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  103. Sep 2020
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    Targeting Lymph Node Niches Enhances Type 1 Immune Responses to Immunization
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    Cyclopentenone Prostaglandins and Structurally Related Oxidized Lipid Species Instigate and Share Distinct Pro- and Anti-inflammatory Pathways
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    Hematopoietic Stem and Progenitor Cells Exhibit Stage-Specific Translational Programs via mTOR- and CDK1-Dependent Mechanisms
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    ADORA1 Inhibition Promotes Tumor Immune Evasion by Regulating the ATF3-PD-L1 Axis
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    Thioredoxin-1 distinctly promotes NF-κB target DNA binding and NLRP3 inflammasome activation independently of Txnip
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    Quantitative analysis of how Myc controls T cell proteomes and metabolic pathways during T cell activation
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  111. Jan 2020
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    Pro-Survival Lipid Sphingosine-1-Phosphate Metabolically Programs T Cells to Limit Anti-tumor Activity
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    Robust Iterative Stimulation with Self-Antigens Overcomes CD8+ T Cell Tolerance to Self- and Tumor Antigens
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    Activation of Mevalonate Pathway via LKB1 Is Essential for Stability of Treg Cells
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    Polyamines Control eIF5A Hypusination, TFEB Translation, and Autophagy to Reverse B Cell Senescence
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    Interstitial Migration of CD8αβ T Cells in the Small Intestine Is Dynamic and Is Dictated by Environmental Cues
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      DOI: 10.1016/j.celrep.2019.02.034

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    1. scibot 12 Jan 2020
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      DOI: 10.1016/j.immuni.2019.04.010

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  118. Nov 2018
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    Dietary Fiber Confers Protection against Flu by Shaping Ly6c− Patrolling Monocyte Hematopoiesis and CD8+ T Cell Metabolism
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    KLRG1+ Effector CD8+ T Cells Lose KLRG1, Differentiate into All Memory T Cell Lineages, and Convey Enhanced Protective Immunity
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    CD38-NAD+Axis Regulates Immunotherapeutic Anti-Tumor T Cell Response
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  122. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    CRIg, a tissue-resident macrophage specific immune checkpoint molecule, promotes immunological tolerance in NOD mice, via a dual role in effector and regulatory T cells
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    Crucial role for T cell-intrinsic IL-18R-MyD88 signaling in cognate immune response to intracellular parasite infection.
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    Granulocyte-Monocyte Progenitors and Monocyte-Dendritic Cell Progenitors Independently Produce Functionally Distinct Monocytes
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  125. Nov 2017
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    Analyses of a Mutant Foxp3 Allele Reveal BATF as a Critical Transcription Factor in the Differentiation and Accumulation of Tissue Regulatory T Cells
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    Long-term intravital imaging of the multicolor-coded tumor microenvironment during combination immunotherapy
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