85 Matching Annotations
  1. Apr 2024
  2. www.sciencedirect.com www.sciencedirect.com
    Ultrasound-visible engineered bacteria for tumor chemo-immunotherapy
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    1. scibot 20 Apr 2024
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    sciencedirect.com/science/article/pii/S2666379124001812
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    Viral infection and spread are inhibited by the polyubiquitination and downregulation of TRPV2 channel by the interferon-stimulated gene TRIM21
    1
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    sciencedirect.com/science/article/pii/S2211124724004236
  4. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The crosstalk between intestinal microbiota and MDSCs fuels colitis associated cancer development
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    1. scibot 18 Apr 2024
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      DOI: 10.1158/2767-9764.CRC-23-0421

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    ncbi.nlm.nih.gov/pmc/articles/PMC11017962/
  5. faseb.onlinelibrary.wiley.com faseb.onlinelibrary.wiley.com
    The ecotin-like peptidase inhibitor of Trypanosoma cruzi prevents TMPRSS2-PAR2-TLR4 crosstalk downmodulating infection and inflammation
    1
    1. scibot 11 Apr 2024
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    faseb.onlinelibrary.wiley.com/doi/10.1096/fj.202302091RR
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    The UBE2F-CRL5ASB11-DIRAS2 axis is an oncogene and tumor suppressor cascade in pancreatic cancer cells
    1
    1. scibot 04 Apr 2024
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      DOI: 10.1016/j.devcel.2024.03.018

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    sciencedirect.com/science/article/pii/S1534580724001837
  7. www.sciencedirect.com www.sciencedirect.com
    Cancer SLC6A6-mediated taurine uptake transactivates immune checkpoint genes and induces exhaustion in CD8+ T cells
    1
    1. scibot 02 Apr 2024
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    sciencedirect.com/science/article/pii/S0092867424003039
  8. Mar 2024
  9. www.sciencedirect.com www.sciencedirect.com
    Phototruncation cell tracking with near-infrared photoimmunotherapy using heptamethine cyanine dye to visualise migratory dynamics of immune cells
    1
    1. scibot 19 Mar 2024
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    sciencedirect.com/science/article/pii/S2352396424000859
  10. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Machine learning predictions of T cell antigen specificity from intracellular calcium dynamics
    1
    1. scibot 09 Mar 2024
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      DOI: 10.1126/sciadv.adk2298

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    ncbi.nlm.nih.gov/pmc/articles/PMC10917351/
  11. 52.53.155.43 52.53.155.43
    LC3-dependent extracellular vesicles (LDEVs) promote M-MDSC accumulation and immunosuppression in colorectal cancer.
    1
    1. scibot 08 Mar 2024
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    52.53.155.43/f6f930ecf0ad11fcfb4027b99fa0ee6fde8d8158/1-s2.0-S2589004224004930-main-html.html
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    Leishmania braziliensis enhances monocyte responses to promote anti-tumor activity
    1
    1. scibot 08 Mar 2024
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    sciencedirect.com/science/article/pii/S2211124724002602
  13. Jan 2024
  14. www.sciencedirect.com www.sciencedirect.com
    Type 2 cytokine signaling in macrophages protects from cellular senescence and organismal aging
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    1. scibot 23 Jan 2024
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    sciencedirect.com/science/article/pii/S1074761324000268
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    ABCG2 is an itaconate exporter that limits antibacterial innate immunity by alleviating TFEB-dependent lysosomal biogenesis
    1
    1. scibot 11 Jan 2024
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      DOI: 10.1016/j.cmet.2023.12.015

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    sciencedirect.com/science/article/pii/S1550413123004655
  16. Dec 2023
  17. www.sciencedirect.com www.sciencedirect.com
    Needle biopsy accelerates pro-metastatic changes and systemic dissemination in breast cancer: Implications for mortality by surgery delay
    1
    1. scibot 20 Dec 2023
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    sciencedirect.com/science/article/pii/S2666379123005475
  18. www.biorxiv.org www.biorxiv.org
    Monocyte-derived microglia with Dnmt3a mutation cause motor pathology in aging mice
    1
    1. scibot 01 Dec 2023
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      DOI: 10.1101/2023.11.16.567402

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    biorxiv.org/content/10.1101/2023.11.16.567402v1
  19. Nov 2023
  20. www.sciencedirect.com www.sciencedirect.com
    Mice with FVB-derived sequence on chromosome 17 succumb to disseminated virus infection due to aberrant NK cell and T cell responses
    1
    1. scibot 18 Nov 2023
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      DOI: 10.1016/j.isci.2023.108348

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    sciencedirect.com/science/article/pii/S2589004223024252
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    Stress-induced β cell early senescence confers protection against type 1 diabetes
    1
    1. scibot 17 Nov 2023
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    sciencedirect.com/science/article/pii/S1550413123003832
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    FBXO38 mediates FGL1 ubiquitination and degradation to enhance cancer immunity and suppress inflammation
    1
    1. scibot 17 Nov 2023
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      DOI: 10.1016/j.celrep.2023.113362

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    sciencedirect.com/science/article/pii/S2211124723013748
  23. 52.53.155.43 52.53.155.43
    Lactobacillus acidophilus-derived indole lactic acid reverses colitis susceptibility in cesarean-born offspring via activation of AhR
    1
    1. scibot 04 Nov 2023
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    52.53.155.43/6d3cb369970d6af9ee4a6737bc5efd3ec5f8e04b/1-s2.0-S2589004223023568-main-html.html
  24. 52.53.155.43 52.53.155.43
    CD4+LAG3+T cells are decreased in SSc-ILD and affects fibroblast mesenchymal transition by TGF-β3
    1
    1. scibot 04 Nov 2023
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      DOI: 10.1016/j.isci.2023.108225

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    52.53.155.43/5ad643fa5a560812951901941b13e2151ba1a6c6/1-s2.0-S2589004223023027-main-html.html
  25. Oct 2023
  26. www.sciencedirect.com www.sciencedirect.com
    An early glycolysis burst in microglia regulates mitochondrial dysfunction in oligodendrocytes under neuroinflammation
    1
    1. scibot 14 Oct 2023
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      DOI: 10.1016/j.isci.2023.107921

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    sciencedirect.com/science/article/pii/S2589004223019983
  27. Jul 2023
  28. www.sciencedirect.com www.sciencedirect.com
    Development of a DNA aptamer targeting IDO1 with anti-tumor effects
    1
    1. scibot 27 Jul 2023
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      DOI: 10.1016/j.isci.2023.107367

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    sciencedirect.com/science/article/pii/S258900422301444X
  29. Jun 2023
  30. www.sciencedirect.com www.sciencedirect.com
    UBE2M-mediated neddylation of TRIM21 regulates obesity-induced inflammation and metabolic disorders
    1
    1. scibot 21 Jun 2023
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      DOI: 10.1016/j.cmet.2023.05.011

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    sciencedirect.com/science/article/pii/S1550413123002097
  31. May 2023
  32. www.sciencedirect.com www.sciencedirect.com
    Depletion of CUL4B in macrophages ameliorates diabetic kidney disease via miR-194-5p/ITGA9 axis
    1
    1. scibot 24 May 2023
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      DOI: 10.1016/j.celrep.2023.112550

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    sciencedirect.com/science/article/pii/S2211124723005612
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    Airway dysbiosis accelerates lung function decline in chronic obstructive pulmonary disease
    1
    1. scibot 19 May 2023
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      DOI: 10.1016/j.chom.2023.04.018

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    sciencedirect.com/science/article/pii/S1931312823001671
  34. journals.aai.org journals.aai.org
    cGAS Mediates Inflammation by Polarizing Macrophages to M1 Phenotype via the mTORC1 Pathway
    1
    1. scibot 13 May 2023
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      DOI: 10.4049/jimmunol.2200351

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    journals.aai.org/jimmunol/article/210/8/1098/263495/cGAS-Mediates-Inflammation-by-Polarizing
  35. Apr 2023
  36. www.sciencedirect.com www.sciencedirect.com
    β-cell function is regulated by metabolic and epigenetic programming of islet-associated macrophages, involving Axl, Mertk and Tgfβ receptor signaling
    1
    1. scibot 20 Apr 2023
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      DOI: 10.1016/j.isci.2023.106477

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    sciencedirect.com/science/article/pii/S2589004223005540
  37. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    INPP5D modulates TREM2 loss-of-function phenotypes in a β-amyloidosis mouse model
    1
    1. scibot 09 Apr 2023
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      DOI: 10.1016/j.isci.2023.106375

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    ncbi.nlm.nih.gov/pmc/articles/PMC10074152/
  38. Mar 2023
  39. www.sciencedirect.com www.sciencedirect.com
    A small-molecule inhibitor of Keap1–Nrf2 interaction attenuates sepsis by selectively augmenting the antibacterial defence of macrophages at infection sites
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    1. scibot 02 Mar 2023
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      DOI: 10.1016/j.ebiom.2023.104480

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    sciencedirect.com/science/article/pii/S2352396423000452
  40. Feb 2023
  41. www.sciencedirect.com www.sciencedirect.com
    Interplay between liver and blood stages of Plasmodium infection dictates malaria severity via γδ T cells and IL-17-promoted stress erythropoiesis
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    1. scibot 23 Feb 2023
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    sciencedirect.com/science/article/pii/S1074761323000432
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    Periostin deficiency reduces PD-1+ tumor-associated macrophage infiltration and enhances anti-PD-1 efficacy in colorectal cancer
    1
    1. scibot 11 Feb 2023
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    sciencedirect.com/science/article/pii/S2211124723001018
  43. Jan 2023
  44. www.sciencedirect.com www.sciencedirect.com
    The loss of epithelial Smad4 drives immune evasion via CXCL1 while displaying vulnerability to combinatorial immunotherapy in gastric cancer
    1
    1. scibot 28 Jan 2023
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    sciencedirect.com/science/article/pii/S2211124722017740
  45. www.sciencedirect.com www.sciencedirect.com
    Type I interferon/STAT1 signaling regulates UBE2M-mediated antiviral innate immunity in a negative feedback manner
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    sciencedirect.com/science/article/pii/S221112472300013X
  46. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A Genome-wide screen identifies PDPK1 as a target to enhance the efficacy of MEK1/2 inhibitors in NRAS mutant melanoma
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      DOI: 10.1158/0008-5472.CAN-21-3217

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    ncbi.nlm.nih.gov/pmc/articles/PMC9298960/
  47. www.sciencedirect.com www.sciencedirect.com
    Bile acids target mitofusin 2 to differentially regulate innate immunity in physiological versus cholestatic conditions
    1
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      DOI: 10.1016/j.celrep.2023.112011

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    sciencedirect.com/science/article/pii/S2211124723000220
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    Microbiota-dependent proteolysis of gluten subverts diet-mediated protection against type 1 diabetes
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    sciencedirect.com/science/article/pii/S1931312822006102
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    Palmitoylation prevents sustained inflammation by limiting NLRP3 inflammasome activation through chaperone-mediated autophagy
    1
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      DOI: 10.1016/j.molcel.2022.12.002

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    sciencedirect.com/science/article/pii/S1097276522011376
  50. Nov 2022
  51. www.sciencedirect.com www.sciencedirect.com
    Cardiac myosin-specific autoimmune T cells contribute to immune-checkpoint-inhibitor-associated myocarditis
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    1. scibot 10 Nov 2022
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      DOI: 10.1016/j.celrep.2022.111611

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    sciencedirect.com/science/article/pii/S2211124722014802
  52. Oct 2022
  53. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Mouse phospholipid phosphatase 6 regulates dendritic cell cholesterol, macropinocytosis, and allergen sensitization
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      DOI: 10.1016/j.isci.2022.105185

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    ncbi.nlm.nih.gov/pmc/articles/PMC9550614/
  54. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    PD-1 expression on mouse intratumoral NK cells and its effects on NK cell phenotype
    1
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  55. Sep 2022
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  58. Aug 2022
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    The Deubiquitinase OTULIN Is an Essential Negative Regulator of Inflammation and Autoimmunity
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  61. Jul 2022
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    Multiomics reveal the central role of pentose phosphate pathway in resident thymic macrophages to cope with efferocytosis-associated stress
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  66. May 2022
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    Glutaminase inhibition impairs CD8 T cell activation in STK11-/Lkb1-deficient lung cancer
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  72. Jan 2022
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    Myeloid Fbxw7 Prevents Pulmonary Fibrosis by Suppressing TGF-β Production
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  74. Nov 2021
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  76. Sep 2021
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    Mutations in the adenosine deaminase ADAR1 that prevent endogenous Z-RNA binding induce Aicardi-Goutières-syndrome-like encephalopathy
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  79. Aug 2021
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    The Deubiquitinase OTULIN Is an Essential Negative Regulator of Inflammation and Autoimmunity
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  82. Jul 2021
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    The Deubiquitinase OTULIN Is an Essential Negative Regulator of Inflammation and Autoimmunity
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  86. Jun 2021
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  88. May 2021
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    Modulation of neuropathology and cognitive deficits by lipopolysaccharide preconditioning in a mouse pilocarpine model of status epilepticus
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  91. Apr 2021
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    LncRNA CALB2 sponges miR-30b-3p to promote odontoblast differentiation of human dental pulp stem cells via up-regulating RUNX2
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  95. Mar 2021
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    Pin1 Promotes NLRP3 Inflammasome Activation by Phosphorylation of p38 MAPK Pathway in Septic Shock
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  97. Feb 2021
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    Pairwise Stimulations of Pathogen-Sensing Pathways Predict Immune Responses to Multi-adjuvant Combinations
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  105. Jan 2020
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    The expression of keratan sulfate reveals a unique subset of microglia in the mouse hippocampus after pilocarpine‐induced status epileptics
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    Cohesin Members Stag1 and Stag2 Display Distinct Roles in Chromatin Accessibility and Topological Control of HSC Self-Renewal and Differentiation
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    Logic-Gated ROR1 Chimeric Antigen Receptor Expression Rescues T Cell-Mediated Toxicity to Normal Tissues and Enables Selective Tumor Targeting
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  111. Nov 2018
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    PGC-1α Controls Skeletal Stem Cell Fate and Bone-Fat Balance in Osteoporosis and Skeletal Aging by Inducing TAZ
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    A Lipoylated Metabolic Protein Released by Staphylococcus aureus Suppresses Macrophage Activation
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    Synergy between the KEAP1/NRF2 and PI3K Pathways Drives Non-Small-Cell Lung Cancer with an Altered Immune Microenvironment
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    The FGF21-CCL11 Axis Mediates Beiging of White Adipose Tissues by Coupling Sympathetic Nervous System to Type 2 Immunity
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    Brain micro-inflammation at specific vessels dysregulates organ-homeostasis via the activation of a new neural circuit
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    Dicer Deficiency Differentially Impacts Microglia of the Developing and Adult Brain
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