114 Matching Annotations
  1. Apr 2024
  2. www.sciencedirect.com www.sciencedirect.com
    Squalene-epoxidase-catalyzed 24(S),25-epoxycholesterol synthesis promotes trained-immunity-mediated antitumor activity
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    1. scibot 18 Apr 2024
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      DOI: 10.1016/j.celrep.2024.114094

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    2. scibot 18 Apr 2024
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      DOI: 10.1016/j.celrep.2024.114094

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    sciencedirect.com/science/article/pii/S2211124724004224
  3. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Disruption of CD47-SIRPα signalling restores inflammatory function in tumour-associated myeloid derived suppressor cells
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    1. scibot 11 Apr 2024
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      DOI: 10.1016/j.isci.2024.109546

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    ncbi.nlm.nih.gov/pmc/articles/PMC10993187/
  4. www.sciencedirect.com www.sciencedirect.com
    Early-wave macrophages control late hematopoiesis
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    1. scibot 04 Apr 2024
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      DOI: 10.1016/j.devcel.2024.03.013

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    sciencedirect.com/science/article/pii/S1534580724001825
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    Targeting the GPI transamidase subunit GPAA1 abrogates the CD24 immune checkpoint in ovarian cancer
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    1. scibot 04 Apr 2024
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      DOI: 10.1016/j.celrep.2024.114041

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    sciencedirect.com/science/article/pii/S2211124724003693
  6. Mar 2024
  7. www.sciencedirect.com www.sciencedirect.com
    Phototruncation cell tracking with near-infrared photoimmunotherapy using heptamethine cyanine dye to visualise migratory dynamics of immune cells
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    1. scibot 19 Mar 2024
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    sciencedirect.com/science/article/pii/S2352396424000859
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    Wnt5 controls splenic myelopoiesis and neutrophil functional ambivalency during DSS-induced colitis
    3
    1. scibot 14 Mar 2024
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      DOI: 10.1016/j.celrep.2024.113934

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    2. scibot 14 Mar 2024
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      DOI: 10.1016/j.celrep.2024.113934

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    3. scibot 14 Mar 2024
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      DOI: 10.1016/j.celrep.2024.113934

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    sciencedirect.com/science/article/pii/S2211124724002626
  9. link.springer.com link.springer.com
    Leukaemia exposure alters the transcriptional profile and function of BCR::ABL1 negative macrophages in the bone marrow niche
    1
    1. scibot 01 Mar 2024
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      DOI: 10.1038/s41467-024-45471-0

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    link.springer.com/article/10.1038/s41467-024-45471-0
  10. Feb 2024
  11. aacrjournals.org aacrjournals.org
    Single-cell transcriptomics reveals the heterogeneity of the immune landscape of IDH-wildtype high-grade gliomas
    2
    1. scibot 27 Feb 2024
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      DOI: 10.1158/2326-6066.CIR-23-0211

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    2. scibot 06 Feb 2024
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      DOI: 10.1158/2326-6066.CIR-23-0211

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    aacrjournals.org/cancerimmunolres/article/12/2/232/733764/Single-Cell-Transcriptomics-Reveals-the
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    Disruption of MerTK increases the efficacy of checkpoint inhibitor by enhancing ferroptosis and immune response in hepatocellular carcinoma
    3
    1. scibot 21 Feb 2024
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      DOI: 10.1016/j.xcrm.2024.101415

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    2. scibot 21 Feb 2024
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      DOI: 10.1016/j.xcrm.2024.101415

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    3. scibot 21 Feb 2024
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      DOI: 10.1016/j.xcrm.2024.101415

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    sciencedirect.com/science/article/pii/S2666379124000387
  13. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    BPS Publications
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    1. scibot 16 Feb 2024
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      DOI: 10.1111/bph.16286

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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.16286
  14. Jan 2024
  15. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Suppression of neuropathic pain in the circadian clock–deficient Per2m/m mice involves up-regulation of endocannabinoid system
    1
    1. scibot 20 Jan 2024
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      DOI: 10.1093/pnasnexus/pgad482

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    ncbi.nlm.nih.gov/pmc/articles/PMC10794166/
  16. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    O6-Methylguanine DNA Methyltransferase Regulates β-glucan-induced Trained Immunity of Macrophages via Farnesoid X Receptor and AMPK
    1
    1. scibot 20 Jan 2024
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      DOI: 10.1016/j.isci.2023.108733

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    ncbi.nlm.nih.gov/pmc/articles/PMC10792243/
  17. www.sciencedirect.com www.sciencedirect.com
    Lymph node and tumor-associated PD-L1+ macrophages antagonize dendritic cell vaccines by suppressing CD8+ T cells
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    1. scibot 19 Jan 2024
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      DOI: 10.1016/j.xcrm.2023.101377

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    sciencedirect.com/science/article/pii/S2666379123006067
  18. www.sciencedirect.com www.sciencedirect.com
    Renal macrophages monitor and remove particles from urine to prevent tubule obstruction
    1
    1. scibot 11 Jan 2024
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      DOI: 10.1016/j.immuni.2023.12.003

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    sciencedirect.com/science/article/pii/S1074761323005344
  19. Dec 2023
  20. www.sciencedirect.com www.sciencedirect.com
    Tissue factor binds to and inhibits interferon-α receptor 1 signaling
    1
    1. scibot 23 Dec 2023
      RRID:AB_312791

      DOI: 10.1016/j.immuni.2023.11.017

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    sciencedirect.com/science/article/pii/S1074761323004995
  21. Nov 2023
  22. www.sciencedirect.com www.sciencedirect.com
    Keratinocyte FABP5-VCP complex mediates recruitment of neutrophils in psoriasis
    1
    1. scibot 28 Nov 2023
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      DOI: 10.1016/j.celrep.2023.113449

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    sciencedirect.com/science/article/pii/S2211124723014614
  23. Aug 2023
  24. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Reduced smooth muscle-fibroblasts transformation potentially decreases intestinal wound healing and colitis-associated cancer in ageing mice
    1
    1. scibot 12 Aug 2023
      RRID:AB_312791

      DOI: 10.1038/s41392-023-01554-w

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    ncbi.nlm.nih.gov/pmc/articles/PMC10409725/
  25. Jul 2023
  26. www.sciencedirect.com www.sciencedirect.com
    Rebalancing liver-infiltrating CCR3+ and CD206+ monocytes improves diet-induced NAFLD
    1
    1. scibot 08 Jul 2023
      RRID:AB_312791

      DOI: 10.1016/j.celrep.2023.112753

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    sciencedirect.com/science/article/pii/S2211124723007647
  27. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Near-Infrared Photoimmunotherapy Targeting Podoplanin-Expressing Cancer Cells and Cancer-Associated Fibroblasts
    1
    1. scibot 06 Jul 2023
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      DOI: 10.1158/1535-7163.MCT-22-0313

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    ncbi.nlm.nih.gov/pmc/articles/PMC9812859/
  28. Jun 2023
  29. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Polycomb repressive complex 1.1 coordinates homeostatic and emergency myelopoiesis
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    1. scibot 24 Jun 2023
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      DOI: 10.7554/eLife.83004

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    ncbi.nlm.nih.gov/pmc/articles/PMC10287155/
  30. www.sciencedirect.com www.sciencedirect.com
    Polysialylation controls immune function of myeloid cells in murine model of pneumococcal pneumonia
    1
    1. scibot 21 Jun 2023
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      DOI: 10.1016/j.celrep.2023.112648

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    sciencedirect.com/science/article/pii/S2211124723006599
  31. www.sciencedirect.com www.sciencedirect.com
    Platelets and mast cells promote pathogenic eosinophil recruitment during invasive fungal infection via the 5-HIAA-GPR35 ligand-receptor system
    1
    1. scibot 07 Jun 2023
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      DOI: 10.1016/j.immuni.2023.05.006

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    sciencedirect.com/science/article/pii/S1074761323002236
  32. May 2023
  33. www.sciencedirect.com www.sciencedirect.com
    YTHDF2 inhibition potentiates radiotherapy antitumor efficacy
    1
    1. scibot 26 May 2023
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      DOI: 10.1016/j.ccell.2023.04.019

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    sciencedirect.com/science/article/pii/S1535610823001630
  34. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Chronic psychological stress promotes breast cancer pre-metastatic niche formation by mobilizing splenic MDSCs via TAM/CXCL1 signaling
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    1. scibot 23 May 2023
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      DOI: 10.1186/s13046-023-02696-z

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    ncbi.nlm.nih.gov/pmc/articles/PMC10199643/
  35. Apr 2023
  36. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Identification of Membrane-expressed CAPRIN-1 as a Novel and Universal Cancer Target, and Generation of a Therapeutic Anti-CAPRIN-1 Antibody TRK-950
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    1. scibot 20 Apr 2023
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      DOI: 10.1158/2767-9764.CRC-22-0310

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    ncbi.nlm.nih.gov/pmc/articles/PMC10112292/
  37. www.sciencedirect.com www.sciencedirect.com
    Long-term tolerance to skin commensals is established neonatally through a specialized dendritic cell subgroup
    1
    1. scibot 07 Apr 2023
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      DOI: 10.1016/j.immuni.2023.03.008

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    sciencedirect.com/science/article/pii/S1074761323001280
  38. Mar 2023
  39. www.sciencedirect.com www.sciencedirect.com
    m6A-driven SF3B1 translation control steers splicing to direct genome integrity and leukemogenesis
    1
    1. scibot 23 Mar 2023
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      DOI: 10.1016/j.molcel.2023.02.024

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    sciencedirect.com/science/article/pii/S109727652300151X
  40. Feb 2023
  41. www.sciencedirect.com www.sciencedirect.com
    TNFR2+ regulatory T cells protect against bacteremic pneumococcal pneumonia by suppressing IL-17A-producing γδ T cells in the lung
    1
    1. scibot 02 Feb 2023
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      DOI: 10.1016/j.celrep.2023.112054

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    sciencedirect.com/science/article/pii/S2211124723000657
  42. Jan 2023
  43. www.sciencedirect.com www.sciencedirect.com
    Prolonged hypernutrition impairs TREM2-dependent efferocytosis to license chronic liver inflammation and NASH development
    1
    1. scibot 28 Jan 2023
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      DOI: 10.1016/j.immuni.2022.11.013

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    sciencedirect.com/science/article/pii/S1074761322006033
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    Decoding m6A RNA methylome identifies PRMT6-regulated lipid transport promoting AML stem cell maintenance
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      DOI: 10.1016/j.stem.2022.12.003

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    sciencedirect.com/science/article/pii/S1934590922004878
  45. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Diurnal Expression of PD-1 on Tumor-Associated Macrophages Underlies the Dosing Time-Dependent Antitumor Effects of the PD-1/PD-L1 Inhibitor BMS-1 in B16/BL6 Melanoma-Bearing Mice
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    1. scibot 12 Jan 2023
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      DOI: 10.1158/1541-7786.MCR-21-0786

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    ncbi.nlm.nih.gov/pmc/articles/PMC9381128/
  46. Dec 2022
  47. 52.53.155.43 52.53.155.43
    mct-22-0313-html.html
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    1. scibot 30 Dec 2022
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      DOI: 10.1158/1535-7163.MCT-22-0313

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      DOI: 10.1158/1535-7163.MCT-22-0313

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    52.53.155.43/9aeeb9884186033f9ebf1db4fab163d362ed9729/mct-22-0313-html.html
  48. Nov 2022
  49. www.sciencedirect.com www.sciencedirect.com
    STAT3 gain-of-function mutations connect leukemia with autoimmune disease by pathological NKG2Dhi CD8+ T cell dysregulation and accumulation
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    1. scibot 29 Nov 2022
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      DOI: 10.1016/j.immuni.2022.11.001

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    sciencedirect.com/science/article/pii/S107476132200591X
  50. Oct 2022
  51. www.sciencedirect.com www.sciencedirect.com
    The m6A reader IGF2BP2 regulates glutamine metabolism and represents a therapeutic target in acute myeloid leukemia
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    1. scibot 28 Oct 2022
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      DOI: 10.1016/j.ccell.2022.10.004

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    sciencedirect.com/science/article/pii/S1535610822004950
  52. Sep 2022
  53. www.sciencedirect.com www.sciencedirect.com
    Protocol to isolate and analyze mouse bone marrow derived dendritic cells (BMDC)
    1
    1. scibot 11 Sep 2022
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      DOI: 10.1016/j.xpro.2022.101664

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    sciencedirect.com/science/article/pii/S2666166722005445
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    Increased glucose metabolism in TAMs fuels O-GlcNAcylation of lysosomal Cathepsin B to promote cancer metastasis and chemoresistance
    1
    1. scibot 11 Sep 2022
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      DOI: 10.1016/j.ccell.2022.08.012

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  55. Jul 2022
  56. www.nature.com www.nature.com
    Nanocarriers based on bacterial membrane materials for cancer vaccine delivery
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  57. Jun 2022
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    Androgens drive sexual dimorphism in liver metastasis by promoting hepatic accumulation of neutrophils
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    Leucine-tRNA-synthase-2-expressing B cells contribute to colorectal cancer immunoevasion
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    Gut bacterial isoamylamine promotes age-related cognitive dysfunction by promoting microglial cell death
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  61. May 2022
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    Defective fractalkine-CX3CR1 signaling aggravates neuroinflammation and affects recovery from cuprizone-induced demyelination
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  63. aacrjournals.org aacrjournals.org
    Targeted Rejuvenation of Exhausted Chimeric Antigen Receptor T-cells Regresses Refractory Solid Tumors
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  64. Mar 2022
  65. www.sciencedirect.com www.sciencedirect.com
    PTIP governs NAD+ metabolism by regulating CD38 expression to drive macrophage inflammation
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    Deletion of STAT3 from Foxd1 cell population protects mice from kidney fibrosis by inhibiting pericytes trans-differentiation and migration
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  67. Feb 2022
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    Matrix remodeling controls a nuclear lamin A/C-emerin network that directs Wnt-regulated stem cell fate
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    SARS-CoV-2 variants of concern display enhanced intrinsic pathogenic properties and expanded organ tropism in mouse models
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    An oncogenic enhancer encodes selective selenium dependency in AML
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  71. Jan 2022
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    Magnesium sensing via LFA-1 regulates CD8+ T cell effector function
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    ACE2 is the critical in vivo receptor for SARS-CoV-2 in a novel COVID-19 mouse model with TNF- and IFNγ-driven immunopathology
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    Uncontrolled CD21low age-associated and B1 B cell accumulation caused by failure of an EGR2/3 tolerance checkpoint
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    Apolipoprotein E derived from CD11c+ cells ameliorates atherosclerosis
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    Disruption of the IL-33-ST2-AKT signaling axis impairs neurodevelopment by inhibiting microglial metabolic adaptation and phagocytic function
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  77. Dec 2021
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    CD244 expression represents functional decline of murine hematopoietic stem cells after in vitro culture
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  79. Nov 2021
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    Simultaneously Combined Cancer Cell- and CTLA4-Targeted NIR-PIT Causes a Synergistic Treatment Effect in Syngeneic Mouse Models
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  81. Oct 2021
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    Differential m6A RNA landscapes across hematopoiesis reveal a role for IGF2BP2 in preserving hematopoietic stem cell function
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  83. Sep 2021
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    Modulating tumor infiltrating myeloid cells to enhance bispecific antibody-driven T cell infiltration and anti-tumor response
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  85. Aug 2021
  86. www.sciencedirect.com www.sciencedirect.com
    Targeting Pin1 renders pancreatic cancer eradicable by synergizing with immunochemotherapy
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    In vivo imaging of retrovirus infection reveals a role for Siglec-1/CD169 in multiple routes of transmission
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    Protocols for endothelial cell isolation from mouse tissues: kidney, spleen, and testis
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    Expansion of Islet-Resident Macrophages Leads to Inflammation Affecting β Cell Proliferation and Function in Obesity
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  90. Jul 2021
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    A Cellular Taxonomy of the Bone Marrow Stroma in Homeostasis and Leukemia
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    Control of gasdermin D oligomerization and pyroptosis by the Ragulator-Rag-mTORC1 pathway
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    GABA-receptive microglia selectively sculpt developing inhibitory circuits
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  94. Jun 2021
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    NLRC4 inhibits NLRP3 inflammasome and abrogates effective antifungal CD8+ T cell responses
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  96. May 2021
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    Iron activates microglia and directly stimulates indoleamine-2,3-dioxygenase activity in the N171-82Q mouse model of Huntington’s disease
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    β-Glucan-stimulated neutrophil secretion of IL-1α is independent of GSDMD and mediated through extracellular vesicles
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    Mesenchymal Niche-Derived Neuregulin-1 Drives Intestinal Stem Cell Proliferation and Regeneration of Damaged Epithelium
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    Substance P Release by Sensory Neurons Triggers Dendritic Cell Migration and Initiates the Type-2 Immune Response to Allergens
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    Protocols for endothelial cell isolation from mouse tissues: small intestine, colon, heart, and liver
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  102. Apr 2021
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    Cancer Burden Is Controlled by Mural Cell-β3-Integrin Regulated Crosstalk with Tumor Cells
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    Increased stem cell proliferation in atherosclerosis accelerates clonal hematopoiesis
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  105. Mar 2021
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    Ontogenic shifts in cellular fate are linked to proteotype changes in lineage-biased hematopoietic progenitor cells
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    Purification of mouse hepatic non-parenchymal cells or nuclei for use in ChIP-seq and other next-generation sequencing approaches
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    Primary cilia-dependent lipid raft/caveolin dynamics regulate adipogenesis
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    IL-15/IL-15Rα Heterodimeric Complex as Cancer Immunotherapy in Murine Breast Cancer Models
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  110. Dec 2020
  111. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Experimental diffuse brain injury and a model of Alzheimer's disease exhibit disease‐specific changes in sleep and incongruous peripheral inflammation
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  112. Nov 2020
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    Two Aldehyde Clearance Systems Are Essential to Prevent Lethal Formaldehyde Accumulation in Mice and Humans
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  114. Sep 2020
  115. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    Astrocyte- and Neuron-Derived CXCL1 Drives Neutrophil Transmigration and Blood-Brain Barrier Permeability in Viral Encephalitis
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  116. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    Bone Marrow Mesenchymal Stem Cells Support Acute Myeloid Leukemia Bioenergetics and Enhance Antioxidant Defense and Escape from Chemotherapy
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  117. www.cell.com www.cell.com
    A Large Polysaccharide Produced by Helicobacter hepaticus Induces an Anti-inflammatory Gene Signature in Macrophages
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  118. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
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  119. www.sciencedirect.com www.sciencedirect.com
    Leukemogenic Chromatin Alterations Promote AML Leukemia Stem Cells via a KDM4C-ALKBH5-AXL Signaling Axis
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    A Genetic Model to Study the Contribution of Brown and Brite Adipocytes to Metabolism
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    Single-Cell Transcriptome Atlas of Murine Endothelial Cells
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  122. Jan 2020
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    B1 and Marginal Zone B Cells but Not Follicular B2 Cells Require Gpx4 to Prevent Lipid Peroxidation and Ferroptosis
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    Discrimination of Dormant and Active Hematopoietic Stem Cells by G0 Marker Reveals Dormancy Regulation by Cytoplasmic Calcium
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    TCF1 and LEF1 Control Treg Competitive Survival and Tfr Development to Prevent Autoimmune Diseases
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    Remodeling of Bone Marrow Hematopoietic Stem Cell Niches Promotes Myeloid Cell Expansion during Premature or Physiological Aging
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    Polyamines Control eIF5A Hypusination, TFEB Translation, and Autophagy to Reverse B Cell Senescence
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  128. www.sciencedirect.com www.sciencedirect.com
    Tissue-Specific Macrophage Responses to Remote Injury Impact the Outcome of Subsequent Local Immune Challenge
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      DOI: 10.1016/j.immuni.2019.10.010

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    IL-10-Dependent Crosstalk between Murine Marginal Zone B Cells, Macrophages, and CD8α+ Dendritic Cells Promotes Listeria monocytogenes Infection
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  130. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Expansion of Islet-Resident Macrophages Leads to Inflammation Affecting β Cell Proliferation and Function in Obesity
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      DOI: 10.1016/j.cmet.2018.12.003

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  131. www.sciencedirect.com www.sciencedirect.com
    Single-Cell RNA Sequencing of Microglia throughout the Mouse Lifespan and in the Injured Brain Reveals Complex Cell-State Changes
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      DOI: 10.1016/j.immuni.2018.11.004

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      DOI: 10.1016/j.celrep.2019.01.030

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    sciencedirect.com/science/article/pii/S2211124719300397
  133. www.sciencedirect.com www.sciencedirect.com
    Mitochondrial Stress-Initiated Aberrant Activation of the NLRP3 Inflammasome Regulates the Functional Deterioration of Hematopoietic Stem Cell Aging
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      DOI: 10.1016/j.celrep.2018.12.101

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  134. www.sciencedirect.com www.sciencedirect.com
    Energetic Trade-Offs and Hypometabolic States Promote Disease Tolerance
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      DOI: 10.1016/j.cell.2019.01.050

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  136. Nov 2018
  137. www.sciencedirect.com www.sciencedirect.com
    HOXA9 Reprograms the Enhancer Landscape to Promote Leukemogenesis
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    METTL14 Inhibits Hematopoietic Stem/Progenitor Differentiation and Promotes Leukemogenesis via mRNA m6A Modification
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  140. europepmc.org europepmc.org
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  141. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    CRIg, a tissue-resident macrophage specific immune checkpoint molecule, promotes immunological tolerance in NOD mice, via a dual role in effector and regulatory T cells
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    Staphylococcus aureus Virulent PSMα Peptides Induce Keratinocyte Alarmin Release to Orchestrate IL-17-Dependent Skin Inflammation
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  143. Nov 2017
  144. www.sciencedirect.com www.sciencedirect.com
    Autophagy-Dependent Generation of Free Fatty Acids Is Critical for Normal Neutrophil Differentiation
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  145. elifesciences.org elifesciences.org
    Brain micro-inflammation at specific vessels dysregulates organ-homeostasis via the activation of a new neural circuit
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    The DNA Methylcytosine Dioxygenase Tet2 Sustains Immunosuppressive Function of Tumor-Infiltrating Myeloid Cells to Promote Melanoma Progression
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