149 Matching Annotations
  1. Last 7 days
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    QDPR deficiency drives immune suppression in pancreatic cancer
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    sciencedirect.com/science/article/pii/S1550413124001190
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    Mesothelin Secretion by Pancreatic Cancer Cells Co-opts Macrophages and Promotes Metastasis
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    aacrjournals.org/cancerres/article/84/4/527/734130/Mesothelin-Secretion-by-Pancreatic-Cancer-Cells-Co
  4. Apr 2024
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    Intraepithelial mast cells drive gasdermin C-mediated type 2 immunity
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    sciencedirect.com/science/article/pii/S1074761324001389
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    An autophagy program that promotes T cell egress from the lymph node controls responses to immune checkpoint blockade
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    sciencedirect.com/science/article/pii/S2211124724003486
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    Fibrous periosteum repairs bone fracture and maintains the healed bone throughout mouse adulthood
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    sciencedirect.com/science/article/pii/S1534580724001874
  8. Mar 2024
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    MAFB in macrophages regulates cold-induced neuronal density in brown adipose tissue
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    sciencedirect.com/science/article/pii/S2211124724003061
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    IKK2 controls the inflammatory potential of tissue-resident regulatory T cells in a murine gain of function model
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    nature.com/articles/s41467-024-45870-3
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    Tonic TCR and IL-1β signaling mediate phenotypic alterations of naive CD4+ T cells
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    sciencedirect.com/science/article/pii/S2211124724002821
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    Type-I-interferon-responsive microglia shape cortical development and behavior
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    sciencedirect.com/science/article/pii/S0092867424001867
  13. Feb 2024
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    Inflammatory dendritic cells restrain CD11b+CD4+ CTLs via CD200R in human NSCLC
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    sciencedirect.com/science/article/pii/S2211124724000950
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    Tumor-secreted FGF21 acts as an immune suppressor by rewiring cholesterol metabolism of CD8+T cells
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    Mice Generated with Induced Pluripotent Stem Cells Derived from Mucosal-Associated Invariant T Cells
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  17. Nov 2023
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    E3 ligase Trim35 inhibits LSD1 demethylase activity through K63-linked ubiquitination and enhances anti-tumor immunity in NSCLC
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    sciencedirect.com/science/article/pii/S2211124723014894
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    HRS mediates tumor immune evasion by regulating proteostasis-associated interferon pathway activation
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    sciencedirect.com/science/article/pii/S2211124723013645
  20. Oct 2023
  21. www.biorxiv.org www.biorxiv.org
    CCR5 promotes the migration of CD8+ T cells to the leishmanial lesions
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    biorxiv.org/content/10.1101/2023.10.10.561700v1
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    Antigen presentation by tumor-associated macrophages mediates progenitor to terminal exhaustion transition in GBM and other solid tumors
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    Renal tubular epithelial cells are constitutive non-cognate stimulators of resident T cells
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    SSRN-id4540281-html.html
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  25. Sep 2023
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    Hematopoietic cell-derived IL-15 supports NK cell development in scattered and clustered localization within the bone marrow
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    sciencedirect.com/science/article/pii/S2211124723011397
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    Protocol for high-sensitivity western blot on murine hematopoietic stem cells
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    ncbi.nlm.nih.gov/pmc/articles/PMC10519847/
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    Loss of p53 and mutational heterogeneity drives immune resistance in an autochthonous mouse lung cancer model with high tumor mutational burden
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    sciencedirect.com/science/article/abs/pii/S1535610823003227
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    Deletion of the inhibitory co-receptor CTLA4 enhances and invigorates chimeric antigen receptor T cells
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    Interferon-g-dependent interactions between tissue-intrinsic γδ T cells and tissue-infiltrating CD8 T cells limit acute contact dermatitis
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    sciencedirect.com/science/article/pii/S0091674923009818
  31. Aug 2023
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    Enhancing autophagy in CD11c+ antigen-presenting cells as a therapeutic strategy for acute respiratory distress syndrome
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    sciencedirect.com/science/article/pii/S221112472301001X
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    Ablative radiotherapy improves survival but does not cure autochthonous mouse models of prostate and colorectal cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC10412558/
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    Reduced smooth muscle-fibroblasts transformation potentially decreases intestinal wound healing and colitis-associated cancer in ageing mice
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    ncbi.nlm.nih.gov/pmc/articles/PMC10409725/
  35. Jun 2023
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    Single cell RNA sequencing unravels mechanisms underlying senescence-like phenotypes of Alveolar Macrophages
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    METTL3-mediated m6A methylation orchestrates mRNA stability and dsRNA contents to equilibrate γδ T1 and γδ T17 cells
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    ZNF451 favors triple-negative breast cancer progression by enhancing SLUG-mediated CCL5 transcriptional expression
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    MicroRNA-223 limits murine hemogenic endothelial cell specification and myelopoiesis
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    Targeting PCSK9 reduces cancer cell stemness and enhances antitumor immunity in head and neck cancer
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    sciencedirect.com/science/article/pii/S2589004223009938
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    Resistance to mesenchymal reprogramming sustains clonal propagation in metastatic breast cancer
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    sciencedirect.com/science/article/pii/S2211124723005442
  42. May 2023
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    YTHDF2 inhibition potentiates radiotherapy antitumor efficacy
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    sciencedirect.com/science/article/pii/S1535610823001630
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    The enteric nervous system relays psychological stress to intestinal inflammation
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    sciencedirect.com/science/article/pii/S0092867423004750
  45. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Intracellular Adhesion Molecule-1 Improves Responsiveness to Immune Checkpoint Inhibitor by Activating CD8+ T Cells
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      DOI: 10.1002/advs.202204378

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    onlinelibrary.wiley.com/doi/10.1002/advs.202204378
  46. Apr 2023
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    Gut dysbiosis promotes the breakdown of oral tolerance mediated through dysfunction of mucosal dendritic cells
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    A tissue injury sensing and repair pathway distinct from host pathogen defense
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    sciencedirect.com/science/article/pii/S0092867423003288
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    The RNA editor ADAR2 promotes immune cell trafficking by enhancing endothelial responses to interleukin-6 during sterile inflammation
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    An optimized IL-12-Fc expands its therapeutic window, achieving strong activity against mouse tumors at tolerable drug doses
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  51. Mar 2023
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    Transcriptomic atlas and interaction networks of brain cells in mouse CNS demyelination and remyelination
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  53. Feb 2023
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    Pericyte stem cells induce Ly6G+ cell accumulation and immunotherapy resistance in pancreatic cancer
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    Repression of the aryl-hydrocarbon receptor prevents oxidative stress and ferroptosis of intestinal intraepithelial lymphocytes
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    A Cre-deleter specific for embryo-derived brain macrophages reveals distinct features of microglia and border macrophages
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  57. Jan 2023
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    Network analysis of large-scale ImmGen and Tabula Muris datasets highlights metabolic diversity of tissue mononuclear phagocytes
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    Identification of the mouse Kupffer cell receptors recognizing pneumococcal capsules by affinity screening
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    Bispecific PD1-IL2v and anti-PD-L1 break tumor immunity resistance by enhancing stem-like tumor-reactive CD8+ T cells and reprogramming macrophages
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  61. Dec 2022
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    ΔNp63 drives dysplastic alveolar remodeling and restricts epithelial plasticity upon severe lung injury
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  63. Nov 2022
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    DOT1L regulates lipid biosynthesis and inflammatory responses in macrophages and promotes atherosclerotic plaque stability
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    Endocardium-to-coronary artery differentiation during heart development and regeneration involves sequential roles of Bmp2 and Cxcl12/Cxcr4
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    Uncovering the emergence of HSCs in the human fetal bone marrow by single-cell RNA-seq analysis
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  67. Oct 2022
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    TREM2 drives microglia response to amyloid-β via SYK-dependent and -independent pathways
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    Differential plasticity and fate of brain-resident and recruited macrophages during the onset and resolution of neuroinflammation
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  70. Sep 2022
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  72. Aug 2022
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    Faecalibaculum rodentium remodels retinoic acid signaling to govern eosinophil-dependent intestinal epithelial homeostasis
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  74. Jul 2022
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    Keratinocyte-derived defensins activate neutrophil-specific receptors Mrgpra2a/b to prevent skin dysbiosis and bacterial infection
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  76. Jun 2022
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    Genome-wide CRISPR screens of T cell exhaustion identify chromatin remodeling factors that limit T cell persistence
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    Lymphatics act as a signaling hub to regulate intestinal stem cell activity
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    A mechanosensitive lipolytic factor in the bone marrow promotes osteogenesis and lymphopoiesis
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  80. May 2022
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    Integrative analysis of scRNA-seq and scATAC-seq revealed transit-amplifying thymic epithelial cells expressing autoimmune regulator
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    Analysis of the interplay between hepatitis B virus-positive hepatocytes and Kupffer cells ex vivo using mice as a model
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    Interleukin-6 blockade abrogates immunotherapy toxicity and promotes tumor immunity
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  84. Apr 2022
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    Specification of fetal liver endothelial progenitors to functional zonated adult sinusoids requires c-Maf induction
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  86. Mar 2022
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    Lactylation-driven METTL3-mediated RNA m6A modification promotes immunosuppression of tumor-infiltrating myeloid cells
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    In vivo anti-tumor effect of PARP inhibition in IDH1/2 mutant MDS/AML resistant to targeted inhibitors of mutant IDH1/2
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    A non-bactericidal cathelicidin provides prophylactic efficacy against bacterial infection by driving phagocyte influx
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  90. Feb 2022
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    Protocol for influenza A virus infection of mice and viral load determination
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  93. Jan 2022
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    Citrulline depletion by ASS1 is required for proinflammatory macrophage activation and immune responses
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    CRISPitope: A generic platform to model target antigens for adoptive T cell transfer therapy in mouse tumor models
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    Disruption of the IL-33-ST2-AKT signaling axis impairs neurodevelopment by inhibiting microglial metabolic adaptation and phagocytic function
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  97. Dec 2021
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    Stem-like intestinal Th17 cells give rise to pathogenic effector T cells during autoimmunity
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  100. Nov 2021
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    Fragmentation of tissue-resident macrophages during isolation confounds analysis of single-cell preparations from mouse hematopoietic tissues
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    Ileitis-associated tertiary lymphoid organs arise at lymphatic valves and impede mesenteric lymph flow in response to tumor necrosis factor
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    COMMD10 is critical for Kupffer cell survival and controls Ly6Chi monocyte differentiation and inflammation in the injured liver
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    Interleukin-10 induces interferon-γ-dependent emergency myelopoiesis
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  106. Sep 2021
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    Disruption of the endopeptidase ADAM10-Notch signaling axis leads to skin dysbiosis and innate lymphoid cell-mediated hair follicle destruction
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  110. Aug 2021
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    The chemokine CCL1 triggers an AMFR-SPRY1 pathway that promotes differentiation of lung fibroblasts into myofibroblasts and drives pulmonary fibrosis
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    Intercellular cGAMP transmission induces innate immune activation and tissue inflammation in Trex1 deficiency
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  114. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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  118. Jul 2021
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    Colitis-Induced Th17 Cells Increase the Risk for Severe Subsequent Clostridium difficile Infection
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    Transcriptional profiling of breast cancer‐associated lymphatic vessels reveals VCAM‐1 as regulator of lymphatic invasion and permeability
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    Standard screening methods underreport AAV-mediated transduction and gene editing
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    DHX15 is required to control RNA virus-induced intestinal inflammation
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    Aging-associated deficit in CCR7 is linked to worsened glymphatic function, cognition, neuroinflammation, and β-amyloid pathology
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    Coexpression of CD71 and CD117 Identifies an Early Unipotent Neutrophil Progenitor Population in Human Bone Marrow
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    Multi-tissue single-cell analysis deconstructs the complex programs of mouse natural killer and type 1 innate lymphoid cells in tissues and circulation
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  132. Apr 2021
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    Staphylococcus cohnii is a potentially biotherapeutic skin commensal alleviating skin inflammation
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    Single-cell chromatin accessibility landscape identifies tissue repair program in human regulatory T cells
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  137. Mar 2021
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    Enhancing mitochondrial activity in neurons protects against neurodegeneration in a mouse model of multiple sclerosis
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    Comprehensive Profiling of an Aging Immune System Reveals Clonal GZMK+ CD8+ T Cells as Conserved Hallmark of Inflammaging
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    Genome-wide analysis of pseudogenes reveals HBBP1’s human-specific essentiality in erythropoiesis and implication in β-thalassemia
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  141. Feb 2021
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    DNA Sensing in Mismatch Repair-Deficient Tumor Cells Is Essential for Anti-tumor Immunity
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    Interferon-λ Mediates Non-redundant Front-Line Antiviral Protection against Influenza Virus Infection without Compromising Host Fitness
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    Protocol for human placental mesenchymal stem cell therapy in a murine model of intra-abdominal infection of hypervirulent Klebsiella
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  146. Nov 2020
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    MicroRNAs of the miR-17~9 family maintain adipose tissue macrophage homeostasis by sustaining IL-10 expression
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    In Vitro Recapitulation of Murine Thymopoiesis from Single Hematopoietic Stem Cells
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    Human Placental MSC-Secreted IL-1β Enhances Neutrophil Bactericidal Functions during Hypervirulent Klebsiella Infection
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    Brain Endothelial Cells Are Exquisite Sensors of Age-Related Circulatory Cues
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    Ablation of Transcription Factor IRF4 Promotes Transplant Acceptance by Driving Allogenic CD4+ T Cell Dysfunction
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    Lipid-Droplet Formation Drives Pathogenic Group 2 Innate Lymphoid Cells in Airway Inflammation
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    The Immunomodulatory Metabolite Itaconate Modifies NLRP3 and Inhibits Inflammasome Activation
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    An Immunologic Mode of Multigenerational Transmission Governs a Gut Treg Setpoint
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    Single-Cell RNA Sequencing Reveals a Dynamic Stromal Niche That Supports Tumor Growth
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    sciencedirect.com/science/article/pii/S2211124720305817
  158. www.sciencedirect.com www.sciencedirect.com
    ADORA1 Inhibition Promotes Tumor Immune Evasion by Regulating the ATF3-PD-L1 Axis
    1
    1. scibot 09 Sep 2020
      RRID:AB_312981

      DOI: 10.1016/j.ccell.2020.02.006

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    sciencedirect.com/science/article/pii/S1535610820300957
  159. www.sciencedirect.com www.sciencedirect.com
    Macrophage K63-Linked Ubiquitination of YAP Promotes Its Nuclear Localization and Exacerbates Atherosclerosis
    1
    1. scibot 08 Sep 2020
      RRID:AB_312981

      DOI: 10.1016/j.celrep.2020.107990

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    sciencedirect.com/science/article/pii/S221112472030975X
  160. www.sciencedirect.com www.sciencedirect.com
    Visualization of T Cell Migration in the Spleen Reveals a Network of Perivascular Pathways that Guide Entry into T Zones
    1
    1. scibot 05 Sep 2020
      RRID:AB_312981

      DOI: 10.1016/j.immuni.2020.03.010

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    sciencedirect.com/science/article/pii/S1074761320301230
  161. www.sciencedirect.com www.sciencedirect.com
    Multi-lineage Lung Regeneration by Stem Cell Transplantation across Major Genetic Barriers
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      RRID:AB_312981

      DOI: 10.1016/j.celrep.2019.12.058

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    sciencedirect.com/science/article/pii/S2211124719317152
  162. Jan 2020
  163. www.sciencedirect.com www.sciencedirect.com
    Stress-Induced Changes in Bone Marrow Stromal Cell Populations Revealed through Single-Cell Protein Expression Mapping
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      RRID:AB_312981

      DOI: 10.1016/j.stem.2019.06.003

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  164. www.sciencedirect.com www.sciencedirect.com
    Slc6a8-Mediated Creatine Uptake and Accumulation Reprogram Macrophage Polarization via Regulating Cytokine Responses
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    1. scibot 13 Jan 2020
      RRID:AB_312981

      DOI: 10.1016/j.immuni.2019.06.007

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    sciencedirect.com/science/article/pii/S1074761319302778
  165. www.sciencedirect.com www.sciencedirect.com
    STAT3 Activation-Induced Fatty Acid Oxidation in CD8+ T Effector Cells Is Critical for Obesity-Promoted Breast Tumor Growth
    1
    1. scibot 13 Jan 2020
      AB_312981

      DOI: 10.1016/j.cmet.2019.10.013

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    sciencedirect.com/science/article/pii/S1550413119306047
  166. www.sciencedirect.com www.sciencedirect.com
    Gata6+ Pericardial Cavity Macrophages Relocate to the Injured Heart and Prevent Cardiac Fibrosis
    1
    1. scibot 13 Jan 2020
      RRID:AB_312981

      DOI: 10.1016/j.immuni.2019.06.010

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  167. www.sciencedirect.com www.sciencedirect.com
    Metabolite-Sensing Receptor Ffar2 Regulates Colonic Group 3 Innate Lymphoid Cells and Gut Immunity
    1
    1. scibot 13 Jan 2020
      RRID:AB_312981

      DOI: 10.1016/j.immuni.2019.09.014

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  168. www.sciencedirect.com www.sciencedirect.com
    Liver-Derived Signals Sequentially Reprogram Myeloid Enhancers to Initiate and Maintain Kupffer Cell Identity
    1
    1. scibot 13 Jan 2020
      RRID:AB_312981

      DOI: 10.1016/j.immuni.2019.09.002

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    sciencedirect.com/science/article/pii/S1074761319303735
  169. www.sciencedirect.com www.sciencedirect.com
    TNFR2 Signaling Enhances ILC2 Survival, Function, and Induction of Airway Hyperreactivity
    1
    1. scibot 13 Jan 2020
      RRID:AB_312981

      DOI: 10.1016/j.celrep.2019.11.102

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    sciencedirect.com/science/article/pii/S221112471931602X
  170. www.sciencedirect.com www.sciencedirect.com
    Untitled document
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    1. scibot 13 Jan 2020
      RRID:AB_312981

      DOI: 10.1016/j.immuni.2019.04.006

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    sciencedirect.com/science/article/pii/S1074761319301864
  171. www.sciencedirect.com www.sciencedirect.com
    Innate Sensing through Mesenchymal TLR4/MyD88 Signals Promotes Spontaneous Intestinal Tumorigenesis
    1
    1. scibot 13 Jan 2020
      RRID:AB_312981

      DOI: 10.1016/j.celrep.2018.12.072

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    sciencedirect.com/science/article/pii/S2211124718320175
  172. www.sciencedirect.com www.sciencedirect.com
    Single-Cell RNA Sequencing of Microglia throughout the Mouse Lifespan and in the Injured Brain Reveals Complex Cell-State Changes
    1
    1. scibot 13 Jan 2020
      RRID:AB_312981

      DOI: 10.1016/j.immuni.2018.11.004

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    sciencedirect.com/science/article/pii/S1074761318304850
  173. www.sciencedirect.com www.sciencedirect.com
    Untitled document
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    1. scibot 13 Jan 2020
      RRID:AB_312981

      DOI: 10.1016/j.cmet.2019.05.002

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    sciencedirect.com/science/article/pii/S1550413119302426
  174. www.sciencedirect.com www.sciencedirect.com
    Colitis-Induced Th17 Cells Increase the Risk for Severe Subsequent Clostridium difficile Infection
    1
    1. scibot 13 Jan 2020
      RRID:AB_312981

      DOI: 10.1016/j.chom.2019.03.003

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    sciencedirect.com/science/article/pii/S1931312819301155
  175. www.sciencedirect.com www.sciencedirect.com
    Mechanisms of Tumor-Induced Lymphovascular Niche Formation in Draining Lymph Nodes
    1
    1. scibot 12 Jan 2020
      RRID:AB_312981

      DOI: 10.1016/j.celrep.2018.12.002

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    sciencedirect.com/science/article/pii/S2211124718319132
  176. www.sciencedirect.com www.sciencedirect.com
    Energetic Trade-Offs and Hypometabolic States Promote Disease Tolerance
    1
    1. scibot 12 Jan 2020
      RRID:AB_312981

      DOI: 10.1016/j.cell.2019.01.050

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    sciencedirect.com/science/article/pii/S0092867419301138
  177. Nov 2018
  178. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Non-canonical NF-κB Antagonizes STING Sensor-Mediated DNA Sensing in Radiotherapy
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC6775781/
  179. www.sciencedirect.com www.sciencedirect.com
    Chrono-pharmacological Targeting of the CCL2-CCR2 Axis Ameliorates Atherosclerosis
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    sciencedirect.com/science/article/pii/S1550413118303097
  180. www.sciencedirect.com www.sciencedirect.com
    Blocking Neuronal Signaling to Immune Cells Treats Streptococcal Invasive Infection
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    sciencedirect.com/science/article/pii/S0092867418304598
  181. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    CRIg, a tissue-resident macrophage specific immune checkpoint molecule, promotes immunological tolerance in NOD mice, via a dual role in effector and regulatory T cells
    1
    1. scibot 05 Nov 2018
      RRID:AB_312981

      Curator: @evieth

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    ncbi.nlm.nih.gov/pmc/articles/PMC5728720/
  182. www.sciencedirect.com www.sciencedirect.com
    The Cytokine TGF-β Promotes the Development and Homeostasis of Alveolar Macrophages
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    sciencedirect.com/science/article/pii/S1074761317304612
  183. www.sciencedirect.com www.sciencedirect.com
    Ablation of Transcription Factor IRF4 Promotes Transplant Acceptance by Driving Allogenic CD4+ T Cell Dysfunction
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    sciencedirect.com/science/article/pii/S1074761317304806
  184. Nov 2017
  185. www.sciencedirect.com www.sciencedirect.com
    Recruited Monocytes and Type 2 Immunity Promote Lung Regeneration following Pneumonectomy
    1
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      AB_312981

      Curator: @chewbeccax

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    sciencedirect.com/science/article/pii/S1934590917300954
  186. www.sciencedirect.com www.sciencedirect.com
    Interferon-λ Mediates Non-redundant Front-Line Antiviral Protection against Influenza Virus Infection without Compromising Host Fitness
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    sciencedirect.com/science/article/pii/S1074761317301905
  187. www.sciencedirect.com www.sciencedirect.com
    Two-Way Conversion between Lipogenic and Myogenic Fibroblastic Phenotypes Marks the Progression and Resolution of Lung Fibrosis
    1
    1. scibot 08 Nov 2017
      AB_312981

      Curator: @gabimpine

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    sciencedirect.com/science/article/pii/S1934590916303447