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Sep 2026
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Cyclin E-CDK2 regulates cancer cell transcriptional program and response to immunotherapy through BRD4

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  DOI: 10.1016/j.molcel.2026.08.007
  
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sciencedirect.com/science/article/pii/S109727652600554X
Aug 2026
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Cblb Gene Editing in T Cells Sustains Expansion and Immunogenic CAR T Tumor Killing Under Chronic Antigenic Stimulation

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pmc.ncbi.nlm.nih.gov/articles/PMC13464884/
Jun 2026
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Dysregulated NF-κB dynamics impair proteostasis and drive premature differentiation in aging B cell development

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  DOI: 10.1016/j.cpblue.2026.100051
  
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sciencedirect.com/science/article/pii/S3051383926000496
Apr 2026
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MMRN1-EGFR drives sialylglycan-Siglec immune evasion in AML leukemia stem cells

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sciencedirect.com/science/article/pii/S1934590926001220
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STAT5 activation enhances adoptive therapy combined with peptide vaccination by preventing PD-1 inhibition

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  DOI: 10.1158/1535-7163.MCT-24-0505
  
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aacrjournals.org/mct/article/24/3/419/752080/STAT5-Activation-Enhances-Adoptive-Therapy
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Sulfur partitioning from cysteine controls T cell proliferation and effector function

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Mar 2026
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FASN inactivation-induced progranulin (GRN) expression promotes lysosome-dependent cell death to suppress leukemogenesis

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sciencedirect.com/science/article/pii/S2211124726001208
Feb 2026
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Sensory neuron production of substance P and TAFA4 promotes disease tolerance during viral infection

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sciencedirect.com/science/article/pii/S1074761326000439
Dec 2025
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Unconventional CD8+ T cell surveillance of cytomegalovirus via Qa-1/HLA-E–restricted epitope recognition

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1. scibot 23 Dec 2025
  
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  DOI: 10.1126/sciadv.aea8707
  
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  DOI: 10.1126/sciadv.aea8707
  
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science.org/doi/10.1126/sciadv.aea8707
Oct 2025
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TLR ligand sensing by lymph node FRCs directs intranodal lymphocyte accumulation to promote immune responses

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1. scibot 29 Oct 2025
  
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Optimal CXCR5 expression during Tfh maturation involves the Bhlhe40-Pou2af1 axis

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1. scibot 23 Oct 2025
  
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  DOI: 10.1016/j.celrep.2025.116470
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12744931/
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Eomesodermin+ CD4+ T cells are critical for curative immunotherapy outcomes

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  DOI: 10.1016/j.immuni.2025.09.004
  
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sciencedirect.com/science/article/pii/S1074761325004157
Sep 2025
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A mosaic H3 subtype live attenuated influenza vaccine elicits broad immune responses to influenza a viruses

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1. scibot 25 Sep 2025
  
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  DOI: 10.1016/j.vaccine.2025.127776
  
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Sensory neurons shape local macrophage identity via TGF-β signaling

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Aug 2025
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Distinct roles for NF-κB in hematopoietic stem cells and the bone marrow milieu in promoting hematopoietic aging

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  DOI: 10.1016/j.celrep.2025.116193
  
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sciencedirect.com/science/article/pii/S2211124725009647
Jul 2025
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The costimulatory molecule ICOS limits memory-like properties and function of exhausted PD-1+CD8+ T cells

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1. scibot 08 Jul 2025
  
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  DOI: 10.1016/j.immuni.2025.06.001
  
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sciencedirect.com/science/article/pii/S1074761325002481
Jun 2025
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Prolonged but finite antigen presentation promotes reversible defects of “helpless” memory CD8+ T cells

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1. scibot 26 Jun 2025
  
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  DOI: 10.1016/j.immuni.2025.05.025
  
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KMT2D coordinates antiviral CD4+ T cell responses through opposing effects on T follicular helper and cytotoxic gene expression

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1. scibot 03 Jun 2025
  
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  DOI: 10.1016/j.celrep.2025.115775
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12302258/
May 2025
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RAG suppresses group 2 innate lymphoid cells

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  DOI: 10.7554/eLife.98287
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12055012/
Apr 2025
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Pre-existing intratumoral stem-like CD8+ T cells drive radiotherapy-induced tumor immunity

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sciencedirect.com/science/article/pii/S2211124725003377
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Engineering TCR-controlled fuzzy logic into CAR T cells enhances therapeutic specificity

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Pre-existing intratumoral stem-like CD8+ T-cells drive radiotherapy-induced tumor control

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  DOI: 10.1101/2024.10.16.618635
  
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52.53.155.43/ecad09cc9eabd42f0fef0391e2d71b5d66664c67/2024.10.16.618635.full-html.html
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Cancer-cell-derived cGAMP limits the activity of tumor-associated CD8+ T cells

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Sex differences in DNMT3A-mutant clonal hematopoiesis and the effects of estrogen

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sciencedirect.com/science/article/pii/S2211124725002657
Mar 2025
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Decoding the ontogeny of myeloid lineage diversity by cross-species and developmental analyses of hematopoietic progenitor atlases

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Jan 2025
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1-s2.0-S2589004225000707-main-html.html

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52.53.155.43/e22ad0f8d0e449f7284596344d2cc636d4e26c8e/1-s2.0-S2589004225000707-main-html.html
Dec 2024
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Durable lymphocyte subset elimination upon a single dose of AAV-delivered depletion antibody dissects immune control of chronic viral infection

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Nov 2024
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In vivo analysis of CRISPR-edited germinal center murine B cells

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  DOI: 10.3389/fimmu.2024.1473760
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11524869/
Aug 2024
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Fam49b dampens TCR signal strength to regulate survival of positively selected thymocytes and peripheral T cells

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  DOI: 10.7554/eLife.76940
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11333044/
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Galectin-3 induces pathogenic immunosuppressive macrophages through interaction with TREM2 in lung cancer

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  DOI: 10.1186/s13046-024-03124-6
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11321020/
Jul 2024
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The ATP-exporting channel Pannexin 1 promotes CD8+ T cell effector and memory responses

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  DOI: 10.1016/j.isci.2024.110290
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11263643/
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Kmt2c restricts G-CSF-driven HSC mobilization and granulocyte production in a methyltransferase-independent manner

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Endomucin marks quiescent long-term multi-lineage repopulating hematopoietic stem cells and is essential for their transendothelial migration

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May 2024
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T-bet deficiency and Hic1 induction override TGF-β-dependency in the formation of CD103+ intestine-resident memory CD8+ T cells

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1. scibot 23 May 2024
  
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  DOI: 10.1016/j.celrep.2024.114258
  
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Apr 2024
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Tumor cell-intrinsic epigenetic dysregulation shapes cancer-associated fibroblasts heterogeneity to metabolically support pancreatic cancer

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  DOI: 10.1016/j.ccell.2024.03.005
  
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Suppression of adaptive NK cell expansion by macrophage-mediated phagocytosis inhibited by 2B4-CD48

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Deciphering the metabolic heterogeneity of hematopoietic stem cells with single-cell resolution

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ALKBH5 modulates hematopoietic stem and progenitor cell energy metabolism through m6A modification-mediated RNA stability control

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TET2-mediated mRNA demethylation regulates leukemia stem cell homing and self-renewal

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Controlling genetic heterogeneity in gene-edited hematopoietic stem cells by single-cell expansion

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Platelets and mast cells promote pathogenic eosinophil recruitment during invasive fungal infection via the 5-HIAA-GPR35 ligand-receptor system

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SOCS1 regulates a subset of NFκB-target genes through direct chromatin binding and defines macrophage functional phenotypes.

1
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Harnessing matrix stiffness to engineer a bone marrow niche for hematopoietic stem cell rejuvenation

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Hematopoietic stem cells preferentially traffic misfolded proteins to aggresomes and depend on aggrephagy to maintain protein homeostasis

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Temporal dynamics of TNF-mediated changes in hematopoietic stem cell function and recovery

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Original research: Invasive margin tissue-resident macrophages of high CD163 expression impede responses to T cell-based immunotherapy

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HSC-independent definitive hematopoiesis persists into adult life

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B cell receptor signaling in germinal centers prolongs survival and primes B cells for selection

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Small intestine and colon tissue-resident memory CD8+ T cells exhibit molecular heterogeneity and differential dependence on Eomes

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METTL16 drives leukemogenesis and leukemia stem cell self-renewal by reprogramming BCAA metabolism

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Interleukin-33-activated neuropeptide CGRP-producing memory Th2 cells cooperate with somatosensory neurons to induce conjunctival itch

1
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Binary outcomes of enhancer activity underlie stable random monoallelic expression

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Tumor-induced erythroid precursor-differentiated myeloid cells mediate immunosuppression and curtail anti-PD-1/PD-L1 treatment efficacy

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Developmental maturation of the hematopoietic system controlled by a Lin28b-let-7-Cbx2 axis

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Inhibition of CDK4/6 promotes CD8 T cell memory formation

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Disruption of the IL-33-ST2-AKT signaling axis impairs neurodevelopment by inhibiting microglial metabolic adaptation and phagocytic function

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CD244 expression represents functional decline of murine hematopoietic stem cells after in vitro culture

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Pre-existing chromatin accessibility and gene expression differences among naive CD4+ T cells influence effector potential

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Cell size is a determinant of stem cell potential during aging

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IL-33 causes thermogenic failure in aging by expanding dysfunctional adipose ILC2

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Hsf1 promotes hematopoietic stem cell fitness and proteostasis in response to ex vivo culture stress and aging

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Defining T Cell States Associated with Response to Checkpoint Immunotherapy in Melanoma

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Untitled document

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Untitled document

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SPNS2 enables T cell egress from lymph nodes during an immune response

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Single-Cell Analysis of Neonatal HSC Ontogeny Reveals Gradual and Uncoordinated Transcriptional Reprogramming that Begins before Birth

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Endogenous Glucocorticoid Signaling Regulates CD8+ T Cell Differentiation and Development of Dysfunction in the Tumor Microenvironment

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UTX promotes CD8+ T cell-mediated antiviral defenses but reduces T cell durability

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  DOI: 10.1016/j.celrep.2021.108966
  
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The TGF-β superfamily cytokine Activin-A is induced during autoimmune neuroinflammation and drives pathogenic Th17 cell differentiation

1
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Kmt2c mutations enhance HSC self-renewal capacity and convey a selective advantage after chemotherapy

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Dynamic Cardiolipin Synthesis Is Required for CD8+ T Cell Immunity

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Oct 2020
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In Situ Maturation and Tissue Adaptation of Type 2 Innate Lymphoid Cell Progenitors

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1. scibot 01 Oct 2020
  
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  RRID:AB_313443
  
  DOI: 10.1016/j.immuni.2020.09.002
  
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sciencedirect.com/science/article/pii/S1074761320303964
Sep 2020
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Isotype Switching Converts Anti-CD40 Antagonism to Agonism to Elicit Potent Antitumor Activity

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1. scibot 26 Sep 2020
  
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  RRID:AB_313443
  
  DOI: 10.1016/j.ccell.2020.04.013
  
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sciencedirect.com/science/article/pii/S1535610820302129
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CD49a Regulates Cutaneous Resident Memory CD8+ T Cell Persistence and Response

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1. scibot 17 Sep 2020
  
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  RRID:AB_313443
  
  DOI: 10.1016/j.celrep.2020.108085
  
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pubmed.ncbi.nlm.nih.gov/32877667/
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Type I Interferons Suppress Anti-parasitic Immunity and Can Be Targeted to Improve Treatment of Visceral Leishmaniasis

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1. scibot 14 Sep 2020
  
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  DOI: 10.1016/j.celrep.2020.01.099
  
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C/EBPβ-Dependent Epigenetic Memory Induces Trained Immunity in Hematopoietic Stem Cells

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1. scibot 14 Sep 2020
  
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  DOI: 10.1016/j.stem.2020.01.017
  
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sciencedirect.com/science/article/pii/S1934590920300175
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The PD-1 Pathway Regulates Development and Function of Memory CD8+ T Cells following Respiratory Viral Infection

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1. scibot 13 Sep 2020
  
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  DOI: 10.1016/j.celrep.2020.107827
  
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sciencedirect.com/science/article/pii/S2211124720308081
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Cell Competition, the Kinetics of Thymopoiesis, and Thymus Cellularity Are Regulated by Double-Negative 2 to 3 Early Thymocytes

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1. scibot 12 Sep 2020
  
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  DOI: 10.1016/j.celrep.2020.107910
  
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sciencedirect.com/science/article/pii/S2211124720308913
Jan 2020
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Neutrophil Recruitment to Noninvasive MRSA at the Stratum Corneum of Human Skin Mediates Transient Colonization

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1. scibot 13 Jan 2020
  
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  RRID:AB_313443
  
  DOI: 10.1016/j.celrep.2019.09.055
  
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sciencedirect.com/science/article/pii/S2211124719312434
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MHC Class II Antigen Presentation by the Intestinal Epithelium Initiates Graft-versus-Host Disease and Is Influenced by the Microbiota

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1. scibot 13 Jan 2020
  
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  RRID:AB_313443
  
  DOI: 10.1016/j.immuni.2019.08.011
  
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Visualizing the Selectivity and Dynamics of Interferon Signaling In Vivo

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1. scibot 13 Jan 2020
  
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  RRID:AB_313443
  
  DOI: 10.1016/j.celrep.2019.11.021
  
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Concomitant Infection of S. mansoni and H. pylori Promotes Promiscuity of Antigen-Experienced Cells and Primes the Liver for a Lower Fibrotic Response

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1. scibot 13 Jan 2020
  
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  DOI: 10.1016/j.celrep.2019.05.108
  
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Junctional Adhesion Molecule 2 Represents a Subset of Hematopoietic Stem Cells with Enhanced Potential for T Lymphopoiesis

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1. scibot 13 Jan 2020
  
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  RRID:AB_313443
  
  DOI: 10.1016/j.celrep.2019.05.028
  
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sciencedirect.com/science/article/pii/S2211124719306394
Nov 2018
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SYK-CARD9 Signaling Axis Promotes Gut Fungi-Mediated Inflammasome Activation to Restrict Colitis and Colon Cancer

1
1. scibot 05 Nov 2018
  
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Non-canonical NF-κB Antagonizes STING Sensor-Mediated DNA Sensing in Radiotherapy

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1. scibot 05 Nov 2018
  
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ncbi.nlm.nih.gov/pmc/articles/PMC6775781/
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Identification of an Early Unipotent Neutrophil Progenitor with Pro-tumoral Activity in Mouse and Human Bone Marrow

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1. scibot 05 Nov 2018
  
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ncbi.nlm.nih.gov/pmc/articles/PMC6542273/
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Dual Targeting of Oncogenic Activation and Inflammatory Signaling Increases Therapeutic Efficacy in Myeloproliferative Neoplasms

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1. scibot 05 Nov 2018
  
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sciencedirect.com/science/article/pii/S1535610817305123
Nov 2017
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Genomic Characterization of Murine Monocytes Reveals C/EBPβ Transcription Factor Dependence of Ly6C− Cells

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1. scibot 08 Nov 2017
  
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sciencedirect.com/science/article/pii/S1074761317301838

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