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Loss of p53 exacerbates autoimmunity by reprogramming propionyl-CoA metabolism and histone modifications in Treg cells

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1. scibot 17 Mar 2026
  
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  DOI: 10.1016/j.celrep.2026.117084
  
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sciencedirect.com/science/article/pii/S2211124726001622
Mar 2026
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FASN inactivation-induced progranulin (GRN) expression promotes lysosome-dependent cell death to suppress leukemogenesis

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1. scibot 05 Mar 2026
  
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  DOI: 10.1016/j.celrep.2026.117042
  
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sciencedirect.com/science/article/pii/S2211124726001208
Feb 2026
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Metabolic reinvigoration of NK cells by IL-21 enhances immunotherapy against MHC class I-deficient solid tumors

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1. scibot 27 Feb 2026
  
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  DOI: 10.1016/j.celrep.2026.117035
  
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sciencedirect.com/science/article/pii/S2211124726001130
Jan 2026
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Tumor-antigen-independent targeting of solid tumors by armored macrophage-directed anti-TREM2 CAR T cells

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1. scibot 23 Jan 2026
  
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  DOI: 10.1016/j.ccell.2025.11.009
  
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sciencedirect.com/science/article/pii/S1535610825005021
Nov 2025
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Vitamin B6 preserves the stemness-like phenotypes and antitumor ability of CD8+ T cells

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1. scibot 29 Nov 2025
  
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sciencedirect.com:5037/science/article/pii/S1534580725006914
Oct 2025
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In situ extended immune activation instantly after tumor resection by oncolytic virus controls postoperative tumor recurrence

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1. scibot 08 Oct 2025
  
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  DOI: 10.1016/j.xcrm.2025.102399
  
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sciencedirect.com/science/article/pii/S2666379125004720
Sep 2025
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Integrin CD103 expression in naive CD8+ T cells promotes cytokine-driven acquisition of memory phenotype and effector function

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1. scibot 16 Sep 2025
  
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  DOI: 10.1016/j.immuni.2025.08.014
  
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sciencedirect.com/science/article/pii/S1074761325003772
Jul 2025
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The costimulatory molecule ICOS limits memory-like properties and function of exhausted PD-1+CD8+ T cells

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1. scibot 08 Jul 2025
  
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  DOI: 10.1016/j.immuni.2025.06.001
  
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sciencedirect.com/science/article/pii/S1074761325002481
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Mitochondrial complex IV remodeling in tumor-associated macrophages amplifies interferon signaling and promotes anti-tumor immunity

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1. scibot 01 Jul 2025
  
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sciencedirect.com/science/article/pii/S1074761325002754
Jun 2025
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A hypomorphic Il2rb mutant mouse model recapitulates and reveals mechanisms of human T cell immune dysregulation in IL-2Rβ deficiency

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1. scibot 26 Jun 2025
  
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sciencedirect.com/science/article/pii/S2211124725006734
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Transplants foster B cell alloimmunity by relaying extracellular vesicles to follicular dendritic cells

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1. scibot 14 Jun 2025
  
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  DOI: 10.1016/j.celrep.2025.115832
  
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sciencedirect.com/science/article/pii/S2211124725006035
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KMT2D coordinates antiviral CD4+ T cell responses through opposing effects on T follicular helper and cytotoxic gene expression

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1. scibot 03 Jun 2025
  
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  DOI: 10.1016/j.celrep.2025.115775
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12302258/
May 2025
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Enhancer-driven gene regulatory networks reveal transcription factors governing T cell adaptation and differentiation in the tumor microenvironment

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1. scibot 29 May 2025
  
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  DOI: 10.1016/j.immuni.2025.04.030
  
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sciencedirect.com/science/article/pii/S1074761325001931
Apr 2025
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Protocol for investigating the impact of transcription regulator deficiency on tumor-specific CD8+ T cell responses via adoptive cell transfer

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1. scibot 03 Apr 2025
  
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  DOI: 10.1016/j.xpro.2025.103703
  
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sciencedirect.com/science/article/pii/S2666166725001091
Mar 2025
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PDF-html.html

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1. scibot 23 Mar 2025
  
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  AB_313503
  
  DOI: 10.1101/2025.03.19.643961
  
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52.53.155.43/6ffb1e8f8e61cda81dc9b10ac8db2b4f9e212959/PDF-html.html
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Ligand-induced ubiquitination unleashes LAG3 immune checkpoint function by hindering membrane sequestration of signaling motifs

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1. scibot 20 Mar 2025
  
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  DOI: 10.1016/j.cell.2025.02.014
  
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sciencedirect.com/science/article/pii/S0092867425001990
Feb 2025
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Neutrophil-derived vesicles control complement activation to facilitate inflammation resolution

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1. scibot 13 Feb 2025
  
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  DOI: 10.1016/j.cell.2025.01.021
  
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sciencedirect.com/science/article/pii/S0092867425000509
Dec 2024
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Reciprocal regulation of mTORC1 signaling and ribosomal biosynthesis determines cell cycle progression in activated T cells

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1. scibot 20 Dec 2024
  
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  AB_313503
  
  DOI: 10.1126/scisignal.adi8753
  
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science.org/doi/10.1126/scisignal.adi8753
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Hypoxia-inducible factor 2α promotes pathogenic polarization of stem-like Th2 cells via modulation of phospholipid metabolism

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1. scibot 02 Dec 2024
  
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  DOI: 10.1016/j.immuni.2024.11.001
  
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sciencedirect.com/science/article/pii/S1074761324004965
Nov 2024
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In vivo models of subclonal oncogenesis and dependency in hematopoietic malignancy

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1. scibot 20 Nov 2024
  
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  DOI: 10.1016/j.ccell.2024.10.009
  
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sciencedirect.com/science/article/pii/S1535610824003970
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A subset of neutrophils activates anti-tumor immunity and inhibits non-small-cell lung cancer progression

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1. scibot 11 Nov 2024
  
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  DOI: 10.1016/j.devcel.2024.10.010
  
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sciencedirect.com/science/article/pii/S1534580724006294
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In vivo analysis of CRISPR-edited germinal center murine B cells

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1. scibot 07 Nov 2024
  
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  DOI: 10.3389/fimmu.2024.1473760
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11524869/
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Thymosin α1 reverses oncolytic adenovirus-induced M2 polarization of macrophages to improve antitumor immunity and therapeutic efficacy

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1. scibot 07 Nov 2024
  
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  DOI: 10.1016/j.xcrm.2024.101751
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11513825/
Oct 2024
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A Prime-Boost Vaccination Approach Induces Lung Resident Memory CD8+ T Cells Derived from Central Memory T Cells That Prevent Tumor Lung Metastasis

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1. scibot 04 Oct 2024
  
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  DOI: 10.1158/0008-5472.CAN-23-3257
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11443216/
Sep 2024
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Intercellular nanotube-mediated mitochondrial transfer enhances T cell metabolic fitness and antitumor efficacy

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1. scibot 17 Sep 2024
  
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  DOI: 10.1016/j.cell.2024.08.029
  
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sciencedirect.com/science/article/pii/S0092867424009565
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The transcription regulator ID3 maintains tumor-specific memory CD8+ T cells in draining lymph nodes during tumorigenesis

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1. scibot 04 Sep 2024
  
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  AB_313503
  
  DOI: 10.1016/j.celrep.2024.114690
  
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sciencedirect.com/science/article/pii/S2211124724010416
Aug 2024
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Indirect suppression of CD4 T cell activation through LAG-3-mediated trans-endocytosis of MHC class II

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1. scibot 27 Aug 2024
  
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  DOI: 10.1016/j.celrep.2024.114655
  
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sciencedirect.com/science/article/pii/S2211124724010064
Jul 2024
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Endomucin marks quiescent long-term multi-lineage repopulating hematopoietic stem cells and is essential for their transendothelial migration

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1. scibot 12 Jul 2024
  
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  DOI: 10.1016/j.celrep.2024.114475
  
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sciencedirect.com/science/article/pii/S2211124724008040
Jun 2024
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Clonal hematopoiesis driven by mutated DNMT3A promotes inflammatory bone loss

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  DOI: 10.1016/j.cell.2024.05.003
  
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  RRID:AB_313503 DOI:10.1016/j.cell.2024.05.003
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sciencedirect.com/science/article/pii/S0092867424004926
May 2024
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Intestinal CXCR6+ ILC3s migrate to the kidney and exacerbate renal fibrosis via IL-23 receptor signaling enhanced by PD-1 expression

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1. scibot 30 May 2024
  
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  DOI: 10.1016/j.immuni.2024.05.004
  
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sciencedirect.com/science/article/pii/S1074761324002553
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T-bet deficiency and Hic1 induction override TGF-β-dependency in the formation of CD103+ intestine-resident memory CD8+ T cells

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1. scibot 23 May 2024
  
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  DOI: 10.1016/j.celrep.2024.114258
  
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sciencedirect.com/science/article/pii/S2211124724005862
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SMARCA5 reprograms AKR1B1-mediated fructose metabolism to control leukemogenesis

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1. scibot 23 May 2024
  
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  DOI: 10.1016/j.devcel.2024.04.023
  
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sciencedirect.com/science/article/pii/S153458072400296X
Jan 2024
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Formate supplementation enhances anti-tumor CD8+ T cell fitness and efficacy of PD-1 blockade

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1. scibot 11 Jan 2024
  
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  RRID:AB_313503
  
  DOI: 10.1158/2159-8290.CD-22-1301
  
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aacrjournals.org/cancerdiscovery/article/13/12/2566/731588/Formate-Supplementation-Enhances-Antitumor-CD8-T
Dec 2023
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cd-22-1301-html.html

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1. scibot 01 Dec 2023
  
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  DOI: 10.1158/2159-8290.cd-22-1301
  
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52.53.155.43/ed2c7eab61775ee4a9efbdfa91d6b4b18a13354a/cd-22-1301-html.html
Oct 2023
www.embopress.org www.embopress.org

IL-27 produced during acute malaria infection regulates Plasmodium-specific memory CD4+ T cells

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1. scibot 20 Oct 2023
  
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  RRID:AB_313503
  
  DOI: 10.15252/emmm.202317713
  
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Transplantation elicits a clonally diverse CD8+ T cell response that is comprised of potent CD43+ effectors

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Graded expression of the chemokine receptor CX3CR1 marks differentiation states of human and murine T cells and enables cross-species interpretation

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CCR4 and CCR7 differentially regulate thymocyte localization with distinct outcomes for central tolerance

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Vaccine-boosted CAR T crosstalk with host immunity to reject tumors with antigen heterogeneity

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YTHDF2 inhibition potentiates radiotherapy antitumor efficacy

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Asymmetric cell division safeguards memory CD8 T cell development

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Cancer-cell-derived fumarate suppresses the anti-tumor capacity of CD8+ T cells in the tumor microenvironment

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Tissue resident iNKT17 cells facilitate cancer cell extravasation in liver metastasis via interleukin-22

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Interleukin-33-activated neuropeptide CGRP-producing memory Th2 cells cooperate with somatosensory neurons to induce conjunctival itch

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The primordial differentiation of tumor-specific memory CD8+ T cells as bona fide responders to PD-1/PD-L1 blockade in draining lymph nodes

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Influenza A virus infection instructs hematopoiesis to megakaryocyte-lineage output

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Bone marrow hematopoiesis drives multiple sclerosis progression

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Binary outcomes of enhancer activity underlie stable random monoallelic expression

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TNF-α sculpts a maturation process in vivo by pruning tolerogenic dendritic cells

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Detection of CD8+ T cell-mediated immune responses to bacterial infection in mice

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Neoantigen-driven B cell and CD4 T follicular helper cell collaboration promotes anti-tumor CD8 T cell responses

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Liver X receptors regulate natural killer T cell population and antitumor activity in the liver of mice

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Reprogramming NK cells and macrophages via combined antibody and cytokine therapy primes tumors for elimination by checkpoint blockade

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The cell-surface 5′-nucleotidase CD73 defines a functional T memory cell subset that declines with age

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Redundant cytokine requirement for intestinal microbiota-induced Th17 cell differentiation in draining lymph nodes

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Untitled document

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Evaluation of Marijuana Compounds on Neuroimmune Endpoints in Experimental Autoimmune Encephalomyelitis

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NKG2A Blockade Potentiates CD8 T Cell Immunity Induced by Cancer Vaccines

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SPNS2 enables T cell egress from lymph nodes during an immune response

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UTX promotes CD8+ T cell-mediated antiviral defenses but reduces T cell durability

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Self-renewal of double-negative 3 early thymocytes enables thymus autonomy but compromises the β-selection checkpoint

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Dynamic adoption of anergy by antigen-exhausted CD4+ T cells

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IL4I1 Is a Metabolic Immune Checkpoint that Activates the AHR and Promotes Tumor Progression

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Thioredoxin-1 distinctly promotes NF-κB target DNA binding and NLRP3 inflammasome activation independently of Txnip

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Quantitative analysis of how Myc controls T cell proteomes and metabolic pathways during T cell activation

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Cell Competition, the Kinetics of Thymopoiesis, and Thymus Cellularity Are Regulated by Double-Negative 2 to 3 Early Thymocytes

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The PD-1 Pathway Regulates Development and Function of Memory CD8+ T Cells following Respiratory Viral Infection

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Landscape of Exhausted Virus-Specific CD8 T Cells in Chronic LCMV Infection

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Concomitant Infection of S. mansoni and H. pylori Promotes Promiscuity of Antigen-Experienced Cells and Primes the Liver for a Lower Fibrotic Response

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The Cardiac Microenvironment Instructs Divergent Monocyte Fates and Functions in Myocarditis

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Loss of Neurological Disease HSAN-I-Associated Gene SPTLC2 Impairs CD8+ T Cell Responses to Infection by Inhibiting T Cell Metabolic Fitness

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Th9 Cells Represent a Unique Subset of CD4+ T Cells Endowed with the Ability to Eradicate Advanced Tumors

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Dual Targeting of Oncogenic Activation and Inflammatory Signaling Increases Therapeutic Efficacy in Myeloproliferative Neoplasms

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The Cytokine TGF-β Promotes the Development and Homeostasis of Alveolar Macrophages

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The Kinase mTORC1 Promotes the Generation and Suppressive Function of Follicular Regulatory T Cells

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Analyses of a Mutant Foxp3 Allele Reveal BATF as a Critical Transcription Factor in the Differentiation and Accumulation of Tissue Regulatory T Cells

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Dicer Deficiency Differentially Impacts Microglia of the Developing and Adult Brain

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Genomic Characterization of Murine Monocytes Reveals C/EBPβ Transcription Factor Dependence of Ly6C− Cells

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