124 Matching Annotations
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    IL-17A is increased in diabetic wounds and impairs keratinocyte function via histone demethylase JMJD3
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    pmc.ncbi.nlm.nih.gov/articles/PMC12824406/
  3. Dec 2025
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    Notch interaction with RUNX factors regulates initiation of the T-lineage program
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    Nuclear exosome targeting complex safeguards hematopoietic stem cell self-renewal and genomic integrity through resolving R loops
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    TYK2 Promotes Immunosurveillance of Colorectal Cancer Liver Metastasis
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  11. Sep 2025
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    IGF2BP3 redirects glycolytic flux to promote one-carbon metabolism and RNA methylation
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    OGFOD1 enables AML chemo- and nutrient stress resistance by regulating protein synthesis
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    Assessing the impact of TET2 and TET3 deletion in TCRalpha and TCRbeta repertoire in murine CD4 T cells in physiological and pathophysiological conditions
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  15. May 2025
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    Vaccination against helminth IL-33 modulators permits immune-mediated parasite ejection
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  17. Mar 2025
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    Decoding the ontogeny of myeloid lineage diversity by cross-species and developmental analyses of hematopoietic progenitor atlases
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  19. Feb 2025
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    The endogenous antigen-specific CD8+ T cell repertoire is composed of unbiased and biased clonotypes with differential fate commitments
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  21. Dec 2024
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    Reciprocal regulation of mTORC1 signaling and ribosomal biosynthesis determines cell cycle progression in activated T cells
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    Concomitant loss of TET2 and TET3 results in T cell expansion and genomic instability in mice
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  24. Oct 2024
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    Inactive Parp2 causes Tp53-dependent lethal anemia by blocking replication-associated nick ligation in erythroblasts
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  26. Sep 2024
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    The Histone Methyltransferase Setdb2 Modulates Macrophage Phenotype and Uric Acid Production in Diabetic Wound Repair
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    Mapping Distinct Bone Marrow Niche Populations and Their Differentiation Paths
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  29. Aug 2024
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    LAG-3 and PD-1 synergize on CD8+ T cells to drive T cell exhaustion and hinder autocrine IFN-γ-dependent anti-tumor immunity
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  31. Jul 2024
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    Lymphatic-localized Treg-mregDC crosstalk limits antigen trafficking and restrains anti-tumor immunity
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    IRF4 requires ARID1A to establish plasma cell identity in multiple myeloma
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    Prenatal inflammation remodels lung immunity and function by programming ILC2 hyperactivation
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    The activity of early-life gene regulatory elements is hijacked in aging through pervasive AP-1-linked chromatin opening
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    Nynrin preserves hematopoietic stem cell function by inhibiting the mitochondrial permeability transition pore opening
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  37. Apr 2024
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    Early-wave macrophages control late hematopoiesis
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    Cbl-b mitigates the responsiveness of naive CD8+ T cells that experience extensive tonic T cell receptor signaling
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  40. Mar 2024
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    The guanine nucleotide exchange factor Rin-like controls Tfh cell differentiation via CD28 signaling
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  42. Jan 2024
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    Deciphering the metabolic heterogeneity of hematopoietic stem cells with single-cell resolution
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  44. Dec 2023
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    Circulating NK cells establish tissue residency upon acute infection of skin and mediate accelerated effector responses to secondary infection
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    MHC class II regulation of CD8+ T cell tolerance and implications in autoimmunity and cancer immunotherapy
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  47. Oct 2023
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    Akkermansia muciniphila induces slow extramedullary hematopoiesis via cooperative IL-1R/TLR signals
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    Effector memory T cells induce innate inflammation by triggering DNA damage and a non-canonical STING pathway in dendritic cells
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    ApoE enhances mitochondrial metabolism via microRNA-142a/146a-regulated circuits that suppress hematopoiesis and inflammation in hyperlipidemia
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  51. Sep 2023
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    CBFA2T3-GLIS2-dependent pediatric acute megakaryoblastic leukemia is driven by GLIS2 and sensitive to navitoclax
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  53. Aug 2023
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    The miR-17∼92 miRNAs promote plasma cell differentiation by suppressing SOCS3-mediated NIK degradation
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    Transcription factor TCF-1 regulates the functions, but not the development, of lymphoid tissue inducer subsets in different tissues
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  56. Jul 2023
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    Targeted removal of macrophage-secreted interleukin-1 receptor antagonist protects against lethal Candida albicans sepsis
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  58. Mar 2023
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    Temporal dynamics of TNF-mediated changes in hematopoietic stem cell function and recovery
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    The early neutrophil-committed progenitors aberrantly differentiate into immunoregulatory monocytes during emergency myelopoiesis
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  61. Feb 2023
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    IDH2 and TET2 mutations synergize to modulate T Follicular Helper cell functional interactionwith the AITL microenvironment
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  63. Jan 2023
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    SARS-CoV-2 variants induce distinct disease and impact in the bone marrow and thymus of mice
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    Tissue resident iNKT17 cells facilitate cancer cell extravasation in liver metastasis via interleukin-22
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  66. Nov 2022
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    Prenatal inflammation perturbs murine fetal hematopoietic development and causes persistent changes to postnatal immunity
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    Protocol to isolate mature thymic T cell subsets using fluorescence-activated cell sorting for assessing gene expression by RNA-seq and transcription factor binding across the genome by CUT&RUN
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  69. Oct 2022
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    Influenza A virus infection instructs hematopoiesis to megakaryocyte-lineage output
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  71. Aug 2022
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    Interleukin-27 signaling serves as an immunological checkpoint for innate cytotoxic cells to promote hepatocellular carcinoma
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  74. Jun 2022
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    Detection of exogenous DNA uptake by murine dendritic cells
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    Tracking and characterization of partial and full epithelial-mesenchymal transition cells in a mouse model of metastatic breast cancer
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    Indoleamine 2,3-dioxygenase 1 activation in mature cDC1 promotes tolerogenic education of inflammatory cDC2 via metabolic communication
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  78. May 2022
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    Heterochronic parabiosis induces stem cell revitalization and systemic rejuvenation across aged tissues
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    Targeted LC-MS/MS-based metabolomics and lipidomics on limited hematopoietic stem cell numbers
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  81. Apr 2022
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    Binding of LAG-3 to stable peptide-MHC class II limits T cell function and suppresses autoimmunity and anti-cancer immunity
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  83. Mar 2022
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    In vivo anti-tumor effect of PARP inhibition in IDH1/2 mutant MDS/AML resistant to targeted inhibitors of mutant IDH1/2
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  85. Feb 2022
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    Matrix remodeling controls a nuclear lamin A/C-emerin network that directs Wnt-regulated stem cell fate
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    An adjuvant strategy enabled by modulation of the physical properties of microbial ligands expands antigen immunogenicity
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  88. Jan 2022
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    Primary germinal center-resident T follicular helper cells are a physiologically distinct subset of CXCR5hiPD-1hi T follicular helper cells
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    Correlation between circulating innate lymphoid cell precursors and thymic function
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  91. Dec 2021
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    CD244 expression represents functional decline of murine hematopoietic stem cells after in vitro culture
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  93. Nov 2021
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    Distinct contributions of partial and full EMT to breast cancer malignancy
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    Fragmentation of tissue-resident macrophages during isolation confounds analysis of single-cell preparations from mouse hematopoietic tissues
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    The mitochondrial iron transporter ABCB7 is required for B cell development, proliferation, and class switch recombination in mice
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    ncbi.nlm.nih.gov/pmc/articles/PMC8585479/
  97. Oct 2021
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    Mitochondrial metabolism coordinates stage-specific repair processes in macrophages during wound healing
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    Interleukin-10 induces interferon-γ-dependent emergency myelopoiesis
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  100. Sep 2021
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    A Cre-driven allele-conditioning line to interrogate CD4+ conventional T cells
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  102. Aug 2021
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    A histone modifier, ASXL1, interacts with NONO and is involved in paraspeckle formation in hematopoietic cells
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    High glucose macrophage exosomes enhance atherosclerosis by driving cellular proliferation & hematopoiesis
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    Notch-induced endoplasmic reticulum-associated degradation governs mouse thymocyte β−selection
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  108. Jul 2021
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    Foxp1 Is Indispensable for Ductal Morphogenesis and Controls the Exit of Mammary Stem Cells from Quiescence
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    Mitochondrial Stress-Initiated Aberrant Activation of the NLRP3 Inflammasome Regulates the Functional Deterioration of Hematopoietic Stem Cell Aging
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    The Histone Methyltransferase Setdb2 Modulates Macrophage Phenotype and Uric Acid Production in Diabetic Wound Repair
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  112. Jun 2021
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    MYC-mediated early glycolysis negatively regulates proinflammatory responses by controlling IRF4 in inflammatory macrophages
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    Megakaryocyte production is sustained by direct differentiation from erythromyeloid progenitors in the yolk sac until midgestation
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  115. May 2021
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    Differential usage of transcriptional repressor Zeb2 enhancers distinguishes adult and embryonic hematopoiesis
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    Feeding-induced resistance to acute lethal sepsis is dependent on hepatic BMAL1 and FXR signalling
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    The inhibitory receptor TIM-3 limits activation of the cGAS-STING pathway in intra-tumoral dendritic cells by suppressing extracellular DNA uptake
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    Intrinsically disordered Meningioma-1 stabilizes the BAF complex to cause AML
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    Two sequential activation modules control the differentiation of protective T helper-1 (Th1) cells
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    Repetitive Elements Trigger RIG-I-like Receptor Signaling that Regulates the Emergence of Hematopoietic Stem and Progenitor Cells
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    High Amount of Transcription Factor IRF8 Engages AP1-IRF Composite Elements in Enhancers to Direct Type 1 Conventional Dendritic Cell Identity
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  123. Apr 2021
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    Distinct Foxp3 enhancer elements coordinate development, maintenance, and function of regulatory T cells
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    Self-renewal of double-negative 3 early thymocytes enables thymus autonomy but compromises the β-selection checkpoint
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    Decline in IGF1 in the bone marrow microenvironment initiates hematopoietic stem cell aging
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    1. scibot 08 Nov 2017
      Before adding the fluorescently labeled antibodies, Fc-receptors were blocked with anti-CD16/CD32 (Pharmingen) antibodies was performed. Mammary epithelial cells were labeled with antibodies directed against CD24 (Pharmingen #553261), CD49f (Pharmingen #551129) and CD61 (eBioscience #11-0622-82). Non-epithelial cells were excluded using antibodies directed against CD45 (BD #553078), CD31 (BioLegend #102404) and Ter119 (BioLegend #116204)

      Curator: @bandrow

      Curator note: BioLegend Cat# 116204, RRID:AB_313705

      Resource used:

      (BioLegend Cat# 116204, RRID:AB_313705)

      SciCrunch record: RRID:AB_313705

      Alternate resolvers: SciCrunch xml N2T identifiers.org

      What is this?

      RRID:AB_313705 RRIDCUR:Missing
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