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A genome-wide CRISPR screening identifies targets that drive tolerogenic dendritic cells

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1. scibot 11 Nov 2026
  
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  DOI: 10.1016/j.celrep.2026.118212
  
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sciencedirect.com/science/article/pii/S221112472601291X
Oct 2026
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Propionate promotes MHC class I antigen presentation and anti-tumor immunity

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1. scibot 22 Oct 2026
  
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  DOI: 10.1016/j.cmet.2026.09.018
  
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sciencedirect.com/science/article/pii/S1550413126003931
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Spatially tuned localization of interleukins and OX40 agonists enhances synergistic anti-tumor immunity

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1. scibot 10 Oct 2026
  
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  DOI: 10.1016/j.xcrm.2026.103109
  
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sciencedirect.com/science/article/pii/S2666379126005264
Sep 2026
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AIM2 in tregs restrains anti-PD-1 efficacy by reinforcing immune suppression in MC38 colorectal cancer

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1. scibot 27 Sep 2026
  
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  DOI: 10.1016/j.isci.2026.116082
  
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sciencedirect.com/science/article/pii/S2589004226014574
dx.doi.org dx.doi.org

Alox15 restrains glycolysis to support M2 macrophage effector function during helminth immunity

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1. scibot 24 Sep 2026
  
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  DOI: 10.1084/jem.20241620
  
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dx.doi.org/10.1084/jem.20241620
Jul 2026
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Combination of exosome vaccines, lenvatinib, and anti-PD-1 eradicates tumor in autochthonous hepatocellular carcinoma mice

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1. scibot 25 Jul 2026
  
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  DOI: 10.1016/j.xcrm.2026.102933
  
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sciencedirect.com/science/article/pii/S2666379126003502
Jun 2026
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Trans-presentation of IL-6Rα by macrophages drives colorectal cancer development

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1. scibot 23 Jun 2026
  
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  DOI: 10.1016/j.celrep.2026.117549
  
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sciencedirect.com/science/article/pii/S2211124726006273
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Multi-tier signaling and chromatin remodeling coordinate microglia inflammatory states and activities associated with demyelination

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1. scibot 22 Jun 2026
  
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  DOI: 10.1016/j.celrep.2026.117569
  
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sciencedirect.com/science/article/pii/S2211124726006479
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EZH1/2 inhibition improves immunotherapy response through MHC Class II de-repression and neutrophil reprogramming

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1. scibot 11 Jun 2026
  
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  RRID:AB_313777
  
  DOI: 10.64898/2026.06.01.725956
  
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biorxiv.org/content/10.64898/2026.06.01.725956v1
May 2026
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A longitudinal atlas of human psoriatic skin reveals the mechanisms of anti-IL-23 therapy in disrupting the type 17 inflammatory circuit

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1. scibot 29 May 2026
  
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  DOI: 10.1016/j.immuni.2026.05.002
  
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sciencedirect.com/science/article/pii/S1074761326002001
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Targeting ADAR1 p150 triggers tumor inhibition and antitumor immunity to overcome immunotherapy resistance

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1. scibot 22 May 2026
  
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  DOI: 10.1016/j.isci.2026.115978
  
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sciencedirect.com/science/article/pii/S2589004226013532
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mRNA lipid-nanoparticle-mediated mitochondrial apoptosis augments adoptive T cell immunotherapy

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1. scibot 06 May 2026
  
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  DOI: 10.1016/j.xcrm.2026.102706
  
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pmc.ncbi.nlm.nih.gov/articles/PMC13130659/
Apr 2026
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Tumor-intrinsic FDFT1 determines coordinated macrophage anti-tumor immunity

1
1. scibot 30 Apr 2026
  
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  RRID:AB_313777
  
  DOI: 10.1016/j.devcel.2026.04.003
  
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sciencedirect.com/science/article/pii/S1534580726001504
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SIRT6-mediated immunometabolic reprogramming of macrophages drives neutrophilic asthma via LDHA-dependent glycolysis

1
1. scibot 24 Apr 2026
  
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  RRID:AB_313777
  
  DOI: 10.1016/j.celrep.2026.117294
  
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sciencedirect.com/science/article/pii/S2211124726003724
Mar 2026
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Oncolytic virotherapy potentiates chemo-PD-1 immunotherapy by engaging chemo-resistant bystander CD8+ T cells

1
1. scibot 11 Mar 2026
  
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  RRID:AB_313777
  
  DOI: 10.1136/jitc-2026-014897
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12970110/
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IgE-dependent anaphylaxis is regulated by sphingolipid binding to activating and inhibitory CD300 family members

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1. scibot 06 Mar 2026
  
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  AB_313777
  
  DOI: 10.1016/j.celrep.2026.117054
  
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sciencedirect.com/science/article/pii/S2211124726001324
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Potentiating dendritic cell immunotherapy by interrupting the Semaphorin 4D-induced immune-suppressive barrier

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1. scibot 05 Mar 2026
  
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  RRID:AB_313777
  
  DOI: 10.1016/j.celrep.2026.117050
  
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sciencedirect.com/science/article/pii/S2211124726001282
Feb 2026
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Metabolic reinvigoration of NK cells by IL-21 enhances immunotherapy against MHC class I-deficient solid tumors

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1. scibot 27 Feb 2026
  
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  RRID:AB_313777
  
  DOI: 10.1016/j.celrep.2026.117035
  
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sciencedirect.com/science/article/pii/S2211124726001130
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Tfam-mediated metabolic perturbation in RORγt+ lymphocytes impacts intestinal tissue homeostasis and promotes GATA3+RORγt+ innate lymphoid cells

1
1. scibot 12 Feb 2026
  
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  RRID:AB_313777
  
  DOI: 10.1016/j.celrep.2026.116952
  
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sciencedirect.com/science/article/pii/S2211124726000306
Dec 2025
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Microbial-derived immunostimulatory small molecule augments anti-PD-1 therapy in lung cancer

1
1. scibot 20 Dec 2025
  
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  RRID:AB_313777
  
  DOI: 10.1016/j.xcrm.2025.102519
  
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sciencedirect.com:5037/science/article/pii/S2666379125005920
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An IL-12 partial agonist sustains intratumoral lymphocyte activation and detoxifies systemic IL-12 therapy

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1. scibot 20 Dec 2025
  
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  RRID:AB_313777
  
  DOI: 10.1016/j.celrep.2025.116757
  
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sciencedirect.com:5037/science/article/pii/S2211124725015293
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Cryptococcus exploits delayed microglial activation, and microglial osteopontin/Spp1 impairs peripheral host control

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1. scibot 04 Dec 2025
  
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  DOI: 10.1016/j.chom.2025.11.008
  
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sciencedirect.com:5037/science/article/pii/S1931312825004688
Nov 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

DUSP11 is an intracellular innate immune checkpoint in lung adenocarcinoma

1
1. scibot 26 Nov 2025
  
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  DOI: 10.1158/2326-6066.CIR-25-0086
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12642826/
Oct 2025
54.241.53.176 54.241.53.176

1-s2.0-S258900422502125X-main-html.html

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1. scibot 28 Oct 2025
  
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  RRID:AB_313777
  
  DOI: 10.1016/j.isci.2025.113864
  
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54.241.53.176/2a706a299ce4031218c49229cc6e3a2577bd770d/1-s2.0-S258900422502125X-main-html.html
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Cancer cells co-opt an inter-organ neuroimmune circuit to escape immune surveillance

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1. scibot 25 Oct 2025
  
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  RRID:AB_313777
  
  DOI: 10.1016/j.cell.2025.09.029
  
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sciencedirect.com/science/article/pii/S0092867425011298
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TYK2 Promotes Immunosurveillance of Colorectal Cancer Liver Metastasis

1
1. scibot 23 Oct 2025
  
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  RRID:AB_313777
  
  DOI: 10.1158/0008-5472.CAN-24-4224
  
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pmc.ncbi.nlm.nih.gov/articles/PMC7618269/
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Eomesodermin+ CD4+ T cells are critical for curative immunotherapy outcomes

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1. scibot 04 Oct 2025
  
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  RRID:AB_313777
  
  DOI: 10.1016/j.immuni.2025.09.004
  
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sciencedirect.com/science/article/pii/S1074761325004157
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CD169+ macrophages identify and eliminate tumor cells in colorectal cancer through CD169/CD43 interaction and FasL-driven apoptosis

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1. scibot 01 Oct 2025
  
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  RRID:AB_313777
  
  DOI: 10.1016/j.celrep.2025.116351
  
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sciencedirect.com/science/article/pii/S2211124725011222
Sep 2025
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RSK1 reprograms the ubiquitin pathway to promote immune suppression

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1. scibot 23 Sep 2025
  
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  DOI: 10.1016/j.celrep.2025.116323
  
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sciencedirect.com/science/article/pii/S2211124725010940
Aug 2025
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Checkpoint antibody receptor modified ARMed CAR T circumvents the suppressive immunome in GBM

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1. scibot 16 Aug 2025
  
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  DOI: 10.3389/fimmu.2025.1579925
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12351401/
52.53.155.43 52.53.155.43

1-s2.0-S2589004225015111-main-html.html

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1. scibot 01 Aug 2025
  
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  DOI: 10.1016/j.isci.2025.113250
  
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52.53.155.43/a3f5a6babd102e0b4daf6c38e342245ea1cdb42a/1-s2.0-S2589004225015111-main-html.html
Jul 2025
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Cancer immunology data engine reveals secreted AOAH as a potential immunotherapy

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1. scibot 29 Jul 2025
  
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  DOI: 10.1016/j.cell.2025.07.004
  
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sciencedirect.com/science/article/pii/S0092867425007937
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Glucose restriction shapes pre-metastatic innate immune landscapes in the lung through exosomal TRAIL

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1. scibot 16 Jul 2025
  
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  DOI: 10.1016/j.cell.2025.06.027
  
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sciencedirect.com/science/article/pii/S0092867425007287
Jun 2025
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Nociceptor-derived CGRP enhances dermal type I conventional dendritic cell function to drive autoreactive CD8+ T cell responses in vitiligo

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1. scibot 17 Jun 2025
  
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  DOI: 10.1016/j.immuni.2025.05.018
  
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sciencedirect.com/science/article/pii/S1074761325002390
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Multi-omics and functional characterization of the tumor-killing capacity of Imiquimod-activated plasmacytoid dendritic cells

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1. scibot 12 Jun 2025
  
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  RRID:AB_313777
  
  DOI: 10.1016/j.isci.2025.112670
  
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sciencedirect.com/science/article/pii/S2589004225009319
May 2025
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Nerve- and airway-associated interstitial macrophages mitigate SARS-CoV-2 pathogenesis via type I interferon signaling

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1. scibot 17 May 2025
  
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  RRID:AB_313777
  
  DOI: 10.1016/j.immuni.2025.04.001
  
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Mar 2025
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A pan-family screen of nuclear receptors in immunocytes reveals ligand-dependent inflammasome control

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HDAC1 fine-tunes Th17 polarization in vivo to restrain tissue damage in fungal infections

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Aberrant zonal recycling of germinal center B cells impairs appropriate selection in lupus

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Aug 2024
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A hepatocyte-specific transcriptional program driven by Rela and Stat3 exacerbates experimental colitis in mice by modulating bile synthesis

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Jul 2024
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de057abe614262e4e5c59c6683970ba76047-html.html

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May 2024
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Gingival-derived mesenchymal stem cells alleviate allergic asthma inflammation via HGF in animal models

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Apr 2024
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IGSF8 is an innate immune checkpoint and cancer immunotherapy target

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Suppression of adaptive NK cell expansion by macrophage-mediated phagocytosis inhibited by 2B4-CD48

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Ex vivo photothermal treatment-induced immunogenic cell death for anticancer vaccine development

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Dec 2023
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Attenuation of allergen-specific immunotherapy for atopic dermatitis by ectopic colonization of Brevundimonas vesicularis in the intestine

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GM-CSF receptor/SYK/JNK/FOXO1/CD11c signaling promotes atherosclerosis

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Interventional hydrogel microsphere vaccine as an immune amplifier for activated antitumour immunity after ablation therapy

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High-fat-diet-associated intestinal microbiota exacerbates psoriasis-like inflammation by enhancing systemic γδ T cell IL-17 production

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Jun 2023
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Methionine restriction promotes cGAS activation and chromatin untethering through demethylation to enhance antitumor immunity

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May 2023
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A local subset of mesenchymal cells expressing the transcription factor Osr1 orchestrates lymph node initiation

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Mar 2023
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A small-molecule inhibitor of Keap1–Nrf2 interaction attenuates sepsis by selectively augmenting the antibacterial defence of macrophages at infection sites

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Jan 2023
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Network analysis of large-scale ImmGen and Tabula Muris datasets highlights metabolic diversity of tissue mononuclear phagocytes

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Tissue-specific metabolic profile drives iNKT cell function during obesity and liver injury

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May 2022
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Immune-mediated neurodegenerative trait provoked by multimodal derepression of long-interspersed nuclear element-1

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Colony stimulating factor-1 producing endothelial cells and mesenchymal stromal cells maintain monocytes within a perivascular bone marrow niche

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Dec 2021
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Resolving the immune landscape of human prostate at a single-cell level in health and cancer

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Nov 2021
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Fragmentation of tissue-resident macrophages during isolation confounds analysis of single-cell preparations from mouse hematopoietic tissues

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Oct 2021
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Cold exposure protects from neuroinflammation through immunologic reprogramming

1
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  DOI: 10.1016/j.cmet.2021.10.002
  
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BPS Publications

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  DOI: 10.1111/bph.15652
  
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Identification of a Kupffer cell subset capable of reverting the T cell dysfunction induced by hepatocellular priming

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Targeting Pin1 renders pancreatic cancer eradicable by synergizing with immunochemotherapy

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  DOI: 10.1016/j.cell.2021.07.020
  
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Apr 2021
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Increased stem cell proliferation in atherosclerosis accelerates clonal hematopoiesis

1
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  DOI: 10.1016/j.cell.2021.01.049
  
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Sep 2020
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Dysregulated Expression of the Nuclear Exosome Targeting Complex Component Rbm7 in Nonhematopoietic Cells Licenses the Development of Fibrosis

1
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  DOI: 10.1016/j.immuni.2020.02.007
  
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FOXD3 Regulates VISTA Expression in Melanoma

1
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  DOI: 10.1016/j.celrep.2019.12.036
  
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Cell Competition, the Kinetics of Thymopoiesis, and Thymus Cellularity Are Regulated by Double-Negative 2 to 3 Early Thymocytes

1
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  DOI: 10.1016/j.celrep.2020.107910
  
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Aug 2020
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Cell Competition, the Kinetics of Thymopoiesis, and Thymus Cellularity Are Regulated by Double-Negative 2 to 3 Early Thymocytes

1
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Jan 2020
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TCF1 and LEF1 Control Treg Competitive Survival and Tfr Development to Prevent Autoimmune Diseases

1
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  DOI: 10.1016/j.celrep.2019.05.061
  
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S100A4 Protein Is Essential for the Development of Mature Microfold Cells in Peyer’s Patches

1
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  DOI: 10.1016/j.celrep.2019.10.091
  
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sciencedirect.com/science/article/pii/S2211124719314135
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Oral Administration of miR-30d from Feces of MS Patients Suppresses MS-like Symptoms in Mice by Expanding Akkermansia muciniphila

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1. scibot 13 Jan 2020
  
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  RRID:AB_313777
  
  DOI: 10.1016/j.chom.2019.10.008
  
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ncbi.nlm.nih.gov/pmc/articles/PMC6948921/
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Smad7 Controls Immunoregulatory PDL2/1-PD1 Signaling in Intestinal Inflammation and Autoimmunity

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1. scibot 13 Jan 2020
  
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  RRID:AB_313777
  
  DOI: 10.1016/j.celrep.2019.07.065
  
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sciencedirect.com/science/article/pii/S2211124719309696
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The Intestine Harbors Functionally Distinct Homeostatic Tissue-Resident and Inflammatory Th17 Cells

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1. scibot 13 Jan 2020
  
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  DOI: 10.1016/j.immuni.2019.05.004
  
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The Chemoattractant Receptor Ebi2 Drives Intranodal Naive CD4+ T Cell Peripheralization to Promote Effective Adaptive Immunity

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1. scibot 13 Jan 2020
  
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  RRID:AB_313777
  
  DOI: 10.1016/j.immuni.2019.04.001
  
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sciencedirect.com/science/article/pii/S1074761319301815
Nov 2018
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Palmitic Acid Hydroxystearic Acids Activate GPR40, Which Is Involved in Their Beneficial Effects on Glucose Homeostasis

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1. scibot 05 Nov 2018
  
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  RRID:AB_313777
  
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E3 Ligase VHL Promotes Group 2 Innate Lymphoid Cell Maturation and Function via Glycolysis Inhibition and Induction of Interleukin-33 Receptor

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1. scibot 05 Nov 2018
  
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CRIg, a tissue-resident macrophage specific immune checkpoint molecule, promotes immunological tolerance in NOD mice, via a dual role in effector and regulatory T cells

1
1. scibot 05 Nov 2018
  
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  Curator: @evieth
  
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ncbi.nlm.nih.gov/pmc/articles/PMC5728720/
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Crucial role for T cell-intrinsic IL-18R-MyD88 signaling in cognate immune response to intracellular parasite infection.

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1. scibot 05 Nov 2018
  
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  RRID:AB_313777
  
  Curator: @evieth
  
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  (BioLegend Cat# 117308, RRID:AB_313777)
  
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europepmc.org/articles/PMC5629024/

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