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Bifidobacteria-derived exopolysaccharide promotes anti-tumor immunity

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1. scibot 06 Sep 2025
  
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  DOI: 10.1016/j.celrep.2025.116223
  
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sciencedirect.com/science/article/pii/S2211124725009945
Jul 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Activated T Cells Break Tumor Immunosuppression by Macrophage Reeducation

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1. scibot 08 Jul 2025
  
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  DOI: 10.1158/2159-8290.CD-24-0415
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12223510/
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Tumor integrin-targeted glucose oxidase enzyme promotes ROS-mediated cell death that combines with interferon alpha therapy for tumor control

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1. scibot 04 Jul 2025
  
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  DOI: 10.1158/1535-7163.MCT-24-0163
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11695183/
Jun 2025
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Prolonged but finite antigen presentation promotes reversible defects of “helpless” memory CD8+ T cells

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1. scibot 26 Jun 2025
  
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  DOI: 10.1016/j.immuni.2025.05.025
  
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sciencedirect.com/science/article/pii/S1074761325002468
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An organoid co-culture model for probing systemic anti-tumor immunity in lung cancer

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1. scibot 13 Jun 2025
  
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  DOI: 10.1016/j.stem.2025.05.011
  
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sciencedirect.com/science/article/pii/S1934590925001912
May 2025
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Thymic dendritic cell-derived IL-27p28 promotes the establishment of functional bias against IFN-γ production in newly generated CD4+ T cells through STAT1-related epigenetic mechanisms

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1. scibot 22 May 2025
  
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  DOI: 10.7554/eLife.96868
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12077877/
Mar 2025
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Lactylation of LSD1 is an acquired epigenetic vulnerability of BRAFi/MEKi-resistant melanoma

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1. scibot 29 Mar 2025
  
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  DOI: 10.1016/j.devcel.2025.02.016
  
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sciencedirect.com/science/article/pii/S1534580725001212
Feb 2025
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Selective apoptosis of tumor-associated platelets boosts the anti-metastatic potency of PD-1 blockade therapy

1
1. scibot 28 Feb 2025
  
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  DOI: 10.1016/j.xcrm.2025.101984
  
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sciencedirect.com/science/article/pii/S2666379125000576
Jan 2025
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Syngeneic natural killer cell therapy activates dendritic and T cells in metastatic lungs and effectively treats low-burden metastases

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1. scibot 23 Jan 2025
  
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  DOI: 10.7554/eLife.99010
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11750138/
Nov 2024
52.53.155.43 52.53.155.43

strobl-et-al-2024-jak-stat1-as-therapeutic-target-for-egfr-deficiency-associated-inflammation-and-scarring-alopecia-html.html

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1. scibot 14 Nov 2024
  
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  DOI: 10.1038/s44321-024-00166-3
  
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52.53.155.43/586ba8b525e8da6306112d5dd7635949084313ca/strobl-et-al-2024-jak-stat1-as-therapeutic-target-for-egfr-deficiency-associated-inflammation-and-scarring-alopecia-html.html
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JAK-STAT1 as therapeutic target for EGFR deficiency-associated inflammation and scarring alopecia

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1. scibot 14 Nov 2024
  
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  DOI: 10.1038/s44321-024-00166-3
  
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2. scibot 14 Nov 2024
  
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  DOI: 10.1038/s44321-024-00166-3
  
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embopress.org/doi/10.1038/s44321-024-00166-3
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DHDH-mediated D-xylose metabolism induces immune evasion in triple-negative breast cancer

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1. scibot 11 Nov 2024
  
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  DOI: 10.1016/j.medj.2024.10.012
  
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sciencedirect.com/science/article/pii/S2666634024004100
Aug 2024
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Obesity intensifies sex-specific interferon signaling to selectively worsen central nervous system autoimmunity in females

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1. scibot 22 Aug 2024
  
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  DOI: 10.1016/j.cmet.2024.07.017
  
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sciencedirect.com/science/article/pii/S1550413124002882
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Malic enzyme 2 maintains metabolic state and anti-tumor immunity of CD8+ T cells

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1. scibot 22 Aug 2024
  
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  AB_315401
  
  DOI: 10.1016/j.molcel.2024.07.021
  
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sciencedirect.com/science/article/pii/S1097276524006191
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A broad-spectrum multiepitope vaccine against seasonal influenza A and B viruses in mice

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1. scibot 19 Aug 2024
  
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  DOI: 10.1016/j.ebiom.2024.105269
  
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sciencedirect.com/science/article/pii/S2352396424003050
Jul 2024
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Alterations of ceramide synthesis induce PD-L1 internalization and signaling to regulate tumor metastasis and immunotherapy response

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1. scibot 25 Jul 2024
  
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  AB_315401
  
  DOI: 10.1016/j.celrep.2024.114532
  
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sciencedirect.com/science/article/pii/S2211124724008611
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Biomineralization-inspired synthesis of autologous cancer vaccines for personalized metallo-immunotherapy

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1. scibot 14 Jul 2024
  
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  DOI: 10.1016/j.isci.2024.110189
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11233966/
Jun 2024
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Blockage of L2HGDH-mediated S-2HG catabolism orchestrates macrophage polarization to elicit antitumor immunity

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1. scibot 04 Jun 2024
  
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  DOI: 10.1016/j.celrep.2024.114300
  
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sciencedirect.com/science/article/pii/S2211124724006284
May 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

PABPC1L induces IDO1 to promote tryptophan metabolism and immune suppression in renal cell carcinoma

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1. scibot 17 May 2024
  
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  DOI: 10.1158/0008-5472.CAN-23-2521
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11094425/
Apr 2024
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Tim4 enables large peritoneal macrophages to cross-present tumor antigens at early stages of tumorigenesis

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1. scibot 18 Apr 2024
  
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  DOI: 10.1016/j.celrep.2024.114096
  
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sciencedirect.com/science/article/pii/S2211124724004248
Mar 2024
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Tonic TCR and IL-1β signaling mediate phenotypic alterations of naive CD4+ T cells

2
1. scibot 19 Mar 2024
  
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  DOI: 10.1016/j.celrep.2024.113954
  
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  DOI: 10.1016/j.celrep.2024.113954
  
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sciencedirect.com/science/article/pii/S2211124724002821
Feb 2024
52.53.155.43 52.53.155.43

Scarring hair follicle destruction is driven by the collapse of EGFR-protected JAK-STAT1-sensitive stem cell immune privilege

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1. scibot 23 Feb 2024
  
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  DOI: 10.1101/2023.10.11.561653
  
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52.53.155.43/96ec307650875a091f9342a8f5a3978ef308aaef/2023.10.11.561653v1.full-html.html
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A GPCR-neuropeptide axis dampens hyperactive neutrophils by promoting an alternative-like polarization during bacterial infection

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1. scibot 02 Feb 2024
  
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  DOI: 10.1016/j.immuni.2024.01.003
  
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sciencedirect.com/science/article/pii/S1074761324000281
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Reversible, tunable epigenetic silencing of TCF1 generates flexibility in the T cell memory decision

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1. scibot 02 Feb 2024
  
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  DOI: 10.1016/j.immuni.2023.12.006
  
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sciencedirect.com/science/article/pii/S107476132300537X
Jan 2024
52.53.155.43 52.53.155.43

Mitochondria-ER contact mediated by MFN2-SERCA2 interaction supports CD8+ T cell metabolic fitness and function in tumors

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1. scibot 10 Jan 2024
  
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  DOI: 10.1126/sciimmunol.abq2424
  
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52.53.155.43/93ebbe5a83b6a28b0d01edad42fa81f437079176/sciimmunol.abq2424_sm-html.html
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Interferon-stimulated neutrophils as a predictor of immunotherapy response

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1. scibot 09 Jan 2024
  
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  DOI: 10.1016/j.ccell.2023.12.005
  
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sciencedirect.com/science/article/pii/S1535610823004336
Dec 2023
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Reprogramming of tumor-associated macrophages via NEDD4-mediated CSF1R degradation by targeting USP18

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1. scibot 17 Dec 2023
  
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  DOI: 10.1016/j.celrep.2023.113560
  
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sciencedirect.com/science/article/pii/S2211124723015723
Sep 2023
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Bifidobacterium affects antitumor efficacy of oncolytic adenovirus in a mouse model of melanoma

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1. scibot 16 Sep 2023
  
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  DOI: 10.1016/j.isci.2023.107668
  
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sciencedirect.com/science/article/pii/S2589004223017455
Aug 2023
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The two enantiomers of 2-hydroxyglutarate differentially regulate cytotoxic T cell function

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1. scibot 25 Aug 2023
  
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  DOI: 10.1016/j.celrep.2023.113013
  
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sciencedirect.com/science/article/pii/S2211124723010240
May 2023
www.cell.com www.cell.com

Fusobacterium nucleatum-derived succinic acid induces tumor resistance to immunotherapy in colorectal cancer

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1. scibot 03 May 2023
  
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  DOI: 10.1016/j.chom.2023.04.010
  
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cell.com/cell-host-microbe/fulltext/S1931-3128(23)00161-0
Mar 2023
www.embopress.org www.embopress.org

The ion channel CALHM6 controls bacterial infection-induced cellular cross-talk at the immunological synapse

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1. scibot 07 Mar 2023
  
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  RRID:AB_315401
  
  DOI: 10.15252/embj.2022111450
  
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embopress.org/doi/10.15252/embj.2022111450
Feb 2023
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Ambient oxygen levels regulate intestinal dysbiosis and GVHD severity after allogeneic stem cell transplantation

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1. scibot 03 Feb 2023
  
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  DOI: 10.1016/j.immuni.2023.01.007
  
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sciencedirect.com/science/article/pii/S1074761323000171
Sep 2022
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Balance between immunoregulatory B cells and plasma cells drives pancreatic tumor immunity

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1. scibot 13 Sep 2022
  
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  RRID:AB_315401
  
  DOI: 10.1016/j.xcrm.2022.100744
  
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sciencedirect.com/science/article/pii/S2666379122002932
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Platelets control liver tumor growth through P2Y12-dependent CD40L release in NAFLD

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1. scibot 03 Sep 2022
  
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  RRID:AB_315401
  
  DOI: 10.1016/j.ccell.2022.08.004
  
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A FBXO7/EYA2-SCFFBXW7 axis promotes AXL-mediated maintenance of mesenchymal and immune evasion phenotypes of cancer cells

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A genetic screen in macrophages identifies new regulators of IFNγ-inducible MHCII that contribute to T cell activation

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Mitochondrial respiration contributes to the interferon gamma response in antigen-presenting cells

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Untitled document

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Metabolic-Pathway-Based Subtyping of Triple-Negative Breast Cancer Reveals Potential Therapeutic Targets

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TGFβ restricts expansion, survival, and function of T cells within the tuberculous granuloma

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FBXO44 promotes DNA replication-coupled repetitive element silencing in cancer cells

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Oral Administration of Flavonifractor plautii Strongly Suppresses Th2 Immune Responses in Mice

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Untitled document

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A Protective Role for the Lectin CD169/Siglec-1 against a Pathogenic Murine Retrovirus

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