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Therapeutic HPV16 E7 vaccination with CD137 agonism induces tumor regression and durable immunity in mice

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1. scibot 30 Oct 2026
  
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  DOI: 10.1016/j.isci.2026.118018
  
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sciencedirect.com/science/article/pii/S2589004226034012
Sep 2026
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Surface display of co-stimulatory ligand B7H2 on engineered bacteria enhances tumor immunotherapy

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1. scibot 04 Sep 2026
  
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  DOI: 10.1016/j.xcrm.2026.103016
  
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sciencedirect.com/science/article/pii/S2666379126004337
Aug 2026
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Cofilin1-driven cytoskeletal remodeling modulates pan-cancer CD8+ T cell immunotherapy responses

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1. scibot 13 Aug 2026
  
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  DOI: 10.1016/j.xcrm.2026.102984
  
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sciencedirect.com/science/article/pii/S2666379126004015
Jul 2026
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Direct interaction of Vδ7 TCRs with IL17RA drives the differentiation of TH1-like γδT cells

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1. scibot 21 Jul 2026
  
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  DOI: 10.1126/science.adx9264
  
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science.org/doi/10.1126/science.adx9264
May 2026
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Effects of Lycium barbarum polysaccharide on the activation of pathogenic CD4+ T cells in a mouse model of multiple sclerosis

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1. scibot 29 May 2026
  
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  DOI: 10.4103/NRR.NRR-D-24-01093
  
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pmc.ncbi.nlm.nih.gov/articles/PMC13211841/
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Activated T cell extracellular vesicle DNA transfer enhances antigen presentation and anti-tumor immunity

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1. scibot 01 May 2026
  
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  DOI: 10.1016/j.ccell.2026.03.023
  
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pmc.ncbi.nlm.nih.gov/articles/PMC13215210/
Apr 2026
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Krüppel-like factor 2 programs early exhausted T cell states and restrains antiviral immunity

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1. scibot 29 Apr 2026
  
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  DOI: 10.1016/j.immuni.2026.03.029
  
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sciencedirect.com/science/article/pii/S1074761326001408
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Dual-Targeting mRNA Cancer Vaccines for Simultaneous Antigen Presentation in Dendritic and Tumor Cells

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1. scibot 02 Apr 2026
  
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  DOI: 10.1021/acsnano.5c20535
  
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pubs.acs.org/doi/10.1021/acsnano.5c20535
Mar 2026
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Unleashing T cell surveillance for the eradication of quiescent persister tumor cells resistant to neoadjuvant chemotherapy

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1. scibot 27 Mar 2026
  
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  DOI: 10.1016/j.devcel.2026.02.020
  
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sciencedirect.com/science/article/pii/S1534580726000857
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6-Hydroxydopamine promotes antitumor immunity through macrophage remodeling beyond sympathetic ablation

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1. scibot 20 Mar 2026
  
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  DOI: 10.1016/j.neuron.2026.02.028
  
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sciencedirect.com/science/article/pii/S0896627326001339
Feb 2026
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The transcriptional repressor Fli1 inhibits proteostasis during nutrient stress to limit NK cell persistence in solid tumors

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1. scibot 19 Feb 2026
  
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  DOI: 10.1016/j.immuni.2026.01.017
  
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sciencedirect.com/science/article/pii/S107476132600035X
Jan 2026
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Cathepsin-D-mediated MHC class I degradation contributes to immune evasion in colorectal cancer

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1. scibot 06 Jan 2026
  
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  DOI: 10.1016/j.xcrm.2025.102534
  
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sciencedirect.com/science/article/pii/S266637912500607X
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5-HT reuptake blockade induces pyroptosis in BRAFV600E-mutated melanomas via remodeling histone serotonylation

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1. scibot 05 Jan 2026
  
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  RRID:AB_315401
  
  DOI: 10.1016/j.xcrm.2025.102537
  
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sciencedirect.com/science/article/pii/S266637912500610X
Dec 2025
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An innovative engineered IL-10 monomer strengthens T cell-mediated anti-tumor responses through anti-PD-1 cis-delivery

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1. scibot 17 Dec 2025
  
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  DOI: 10.1016/j.xcrm.2025.102515
  
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sciencedirect.com:5037/science/article/pii/S2666379125005889
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1-s2.0-S258900422502646X-main-html.html

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1. scibot 11 Dec 2025
  
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  RRID:AB_315401
  
  DOI: 10.1016/j.isci.2025.114385
  
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54.241.53.176/93de8e6290387b0a29b7a2c9729bf4f9de57ced1/1-s2.0-S258900422502646X-main-html.html
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Sensitized mast cells for targeted drug delivery and augmented cancer immunotherapy

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1. scibot 10 Dec 2025
  
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  RRID:AB_315401
  
  DOI: 10.1016/j.cell.2025.11.015
  
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sciencedirect.com:5037/science/article/pii/S009286742501311X
Sep 2025
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Bifidobacteria-derived exopolysaccharide promotes anti-tumor immunity

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1. scibot 06 Sep 2025
  
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  DOI: 10.1016/j.celrep.2025.116223
  
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sciencedirect.com/science/article/pii/S2211124725009945
Jul 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Activated T Cells Break Tumor Immunosuppression by Macrophage Reeducation

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1. scibot 08 Jul 2025
  
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  RRID:AB_315401
  
  DOI: 10.1158/2159-8290.CD-24-0415
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12223510/
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Tumor integrin-targeted glucose oxidase enzyme promotes ROS-mediated cell death that combines with interferon alpha therapy for tumor control

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1. scibot 04 Jul 2025
  
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  DOI: 10.1158/1535-7163.MCT-24-0163
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11695183/
Jun 2025
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Prolonged but finite antigen presentation promotes reversible defects of “helpless” memory CD8+ T cells

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1. scibot 26 Jun 2025
  
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  DOI: 10.1016/j.immuni.2025.05.025
  
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sciencedirect.com/science/article/pii/S1074761325002468
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An organoid co-culture model for probing systemic anti-tumor immunity in lung cancer

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1. scibot 13 Jun 2025
  
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  DOI: 10.1016/j.stem.2025.05.011
  
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sciencedirect.com/science/article/pii/S1934590925001912
May 2025
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Thymic dendritic cell-derived IL-27p28 promotes the establishment of functional bias against IFN-γ production in newly generated CD4+ T cells through STAT1-related epigenetic mechanisms

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1. scibot 22 May 2025
  
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  RRID:AB_315401
  
  DOI: 10.7554/eLife.96868
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12077877/
Mar 2025
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Lactylation of LSD1 is an acquired epigenetic vulnerability of BRAFi/MEKi-resistant melanoma

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1. scibot 29 Mar 2025
  
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  DOI: 10.1016/j.devcel.2025.02.016
  
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Feb 2025
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Selective apoptosis of tumor-associated platelets boosts the anti-metastatic potency of PD-1 blockade therapy

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1. scibot 28 Feb 2025
  
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  DOI: 10.1016/j.xcrm.2025.101984
  
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sciencedirect.com/science/article/pii/S2666379125000576
Jan 2025
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Syngeneic natural killer cell therapy activates dendritic and T cells in metastatic lungs and effectively treats low-burden metastases

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1. scibot 23 Jan 2025
  
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  DOI: 10.7554/eLife.99010
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11750138/
Nov 2024
52.53.155.43 52.53.155.43

strobl-et-al-2024-jak-stat1-as-therapeutic-target-for-egfr-deficiency-associated-inflammation-and-scarring-alopecia-html.html

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1. scibot 14 Nov 2024
  
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  DOI: 10.1038/s44321-024-00166-3
  
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52.53.155.43/586ba8b525e8da6306112d5dd7635949084313ca/strobl-et-al-2024-jak-stat1-as-therapeutic-target-for-egfr-deficiency-associated-inflammation-and-scarring-alopecia-html.html
www.embopress.org www.embopress.org

JAK-STAT1 as therapeutic target for EGFR deficiency-associated inflammation and scarring alopecia

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1. scibot 14 Nov 2024
  
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  DOI: 10.1038/s44321-024-00166-3
  
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  DOI: 10.1038/s44321-024-00166-3
  
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embopress.org/doi/10.1038/s44321-024-00166-3
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DHDH-mediated D-xylose metabolism induces immune evasion in triple-negative breast cancer

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1. scibot 11 Nov 2024
  
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  DOI: 10.1016/j.medj.2024.10.012
  
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sciencedirect.com/science/article/pii/S2666634024004100
Aug 2024
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Obesity intensifies sex-specific interferon signaling to selectively worsen central nervous system autoimmunity in females

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1. scibot 22 Aug 2024
  
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  DOI: 10.1016/j.cmet.2024.07.017
  
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sciencedirect.com/science/article/pii/S1550413124002882
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Malic enzyme 2 maintains metabolic state and anti-tumor immunity of CD8+ T cells

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1. scibot 22 Aug 2024
  
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  DOI: 10.1016/j.molcel.2024.07.021
  
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sciencedirect.com/science/article/pii/S1097276524006191
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A broad-spectrum multiepitope vaccine against seasonal influenza A and B viruses in mice

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1. scibot 19 Aug 2024
  
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  DOI: 10.1016/j.ebiom.2024.105269
  
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sciencedirect.com/science/article/pii/S2352396424003050
Jul 2024
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Alterations of ceramide synthesis induce PD-L1 internalization and signaling to regulate tumor metastasis and immunotherapy response

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1. scibot 25 Jul 2024
  
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  DOI: 10.1016/j.celrep.2024.114532
  
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sciencedirect.com/science/article/pii/S2211124724008611
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Biomineralization-inspired synthesis of autologous cancer vaccines for personalized metallo-immunotherapy

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1. scibot 14 Jul 2024
  
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  DOI: 10.1016/j.isci.2024.110189
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11233966/
Jun 2024
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Blockage of L2HGDH-mediated S-2HG catabolism orchestrates macrophage polarization to elicit antitumor immunity

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1. scibot 04 Jun 2024
  
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  RRID:AB_315401
  
  DOI: 10.1016/j.celrep.2024.114300
  
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sciencedirect.com/science/article/pii/S2211124724006284
May 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

PABPC1L induces IDO1 to promote tryptophan metabolism and immune suppression in renal cell carcinoma

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Apr 2024
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Tim4 enables large peritoneal macrophages to cross-present tumor antigens at early stages of tumorigenesis

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Mar 2024
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Tonic TCR and IL-1β signaling mediate phenotypic alterations of naive CD4+ T cells

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Feb 2024
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Scarring hair follicle destruction is driven by the collapse of EGFR-protected JAK-STAT1-sensitive stem cell immune privilege

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A GPCR-neuropeptide axis dampens hyperactive neutrophils by promoting an alternative-like polarization during bacterial infection

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Reversible, tunable epigenetic silencing of TCF1 generates flexibility in the T cell memory decision

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Jan 2024
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Mitochondria-ER contact mediated by MFN2-SERCA2 interaction supports CD8+ T cell metabolic fitness and function in tumors

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Interferon-stimulated neutrophils as a predictor of immunotherapy response

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Reprogramming of tumor-associated macrophages via NEDD4-mediated CSF1R degradation by targeting USP18

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Bifidobacterium affects antitumor efficacy of oncolytic adenovirus in a mouse model of melanoma

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The two enantiomers of 2-hydroxyglutarate differentially regulate cytotoxic T cell function

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May 2023
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Fusobacterium nucleatum-derived succinic acid induces tumor resistance to immunotherapy in colorectal cancer

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Mar 2023
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The ion channel CALHM6 controls bacterial infection-induced cellular cross-talk at the immunological synapse

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Feb 2023
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Ambient oxygen levels regulate intestinal dysbiosis and GVHD severity after allogeneic stem cell transplantation

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Sep 2022
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Balance between immunoregulatory B cells and plasma cells drives pancreatic tumor immunity

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Platelets control liver tumor growth through P2Y12-dependent CD40L release in NAFLD

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Feb 2022
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A FBXO7/EYA2-SCFFBXW7 axis promotes AXL-mediated maintenance of mesenchymal and immune evasion phenotypes of cancer cells

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Nov 2021
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A genetic screen in macrophages identifies new regulators of IFNγ-inducible MHCII that contribute to T cell activation

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Mitochondrial respiration contributes to the interferon gamma response in antigen-presenting cells

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Aug 2021
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Untitled document

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Apr 2021
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Metabolic-Pathway-Based Subtyping of Triple-Negative Breast Cancer Reveals Potential Therapeutic Targets

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TGFβ restricts expansion, survival, and function of T cells within the tuberculous granuloma

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Feb 2021
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FBXO44 promotes DNA replication-coupled repetitive element silencing in cancer cells

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Oral Administration of Flavonifractor plautii Strongly Suppresses Th2 Immune Responses in Mice

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Jan 2020
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Untitled document

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A Protective Role for the Lectin CD169/Siglec-1 against a Pathogenic Murine Retrovirus

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