125 Matching Annotations
  1. Last 7 days
  2. www.sciencedirect.com www.sciencedirect.com
    A Th17 cell-intrinsic glutathione/mitochondrial-IL-22 axis protects against intestinal inflammation
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    1. scibot 12 Jul 2024
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    sciencedirect.com/science/article/pii/S1550413124002353
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    SWI/SNF chromatin remodeling factor BAF60b restrains inflammatory diseases by affecting regulatory T cell migration
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      DOI: 10.1016/j.celrep.2024.114458

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    sciencedirect.com/science/article/pii/S2211124724007873
  4. www.cell.com www.cell.com
    Mitochondrial DNA-boosted dendritic cell-based nanovaccination triggers antitumor immunity in lung and pancreatic cancers
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    1. scibot 12 Jul 2024
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      DOI: 10.1016/j.xcrm.2024.101648

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    cell.com/cell-reports-medicine/abstract/S2666-3791(24)00362-8
  5. Jun 2024
  6. www.sciencedirect.com www.sciencedirect.com
    Glycoengineering-based anti-PD-1-iRGD peptide conjugate boosts antitumor efficacy through T cell engagement
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    sciencedirect.com/science/article/pii/S2666379124002829
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    Landscape of tumoral ecosystem for enhanced anti-PD-1 immunotherapy by gut Akkermansia muciniphila
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    sciencedirect.com/science/article/pii/S221112472400634X
  8. May 2024
  9. www.sciencedirect.com www.sciencedirect.com
    CXCL16-dependent scavenging of oxidized lipids by islet macrophages promotes differentiation of pathogenic CD8+ T cells in diabetic autoimmunity
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    1. scibot 16 May 2024
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    Osr2 functions as a biomechanical checkpoint to aggravate CD8+ T cell exhaustion in tumor
    1
    1. scibot 14 May 2024
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    sciencedirect.com/science/article/pii/S0092867424004483
  11. 52.53.155.43 52.53.155.43
    Gingival-derived mesenchymal stem cells alleviate allergic asthma inflammation via HGF in animal models
    1
    1. scibot 10 May 2024
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    52.53.155.43/77b0b81fcd376689bbdc4cf0ee4300be323e1a77/PIIS258900422401040X-html.html
  12. Apr 2024
  13. www.pnas.org www.pnas.org
    Claudin-2 upregulation enhances intestinal permeability, immune activation, dysbiosis, and mortality in sepsis
    1
    1. scibot 25 Apr 2024
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      DOI: 10.1073/pnas.2217877121

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    pnas.org/doi/abs/10.1073/pnas.2217877121
  14. Feb 2024
  15. www.sciencedirect.com www.sciencedirect.com
    Suppression of the METTL3-m6A-integrin β1 axis by extracellular acidification impairs T cell infiltration and antitumor activity
    2
    1. scibot 21 Feb 2024
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    sciencedirect.com/science/article/pii/S2211124724001244
  16. Jan 2024
  17. www.sciencedirect.com www.sciencedirect.com
    Interrogation of endothelial and mural cells in brain metastasis reveals key immune-regulatory mechanisms
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    1. scibot 19 Jan 2024
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    sciencedirect.com/science/article/pii/S1535610823004464
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    Lymph node and tumor-associated PD-L1+ macrophages antagonize dendritic cell vaccines by suppressing CD8+ T cells
    1
    1. scibot 19 Jan 2024
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      DOI: 10.1016/j.xcrm.2023.101377

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    sciencedirect.com/science/article/pii/S2666379123006067
  19. Dec 2023
  20. www.sciencedirect.com www.sciencedirect.com
    Circulating NK cells establish tissue residency upon acute infection of skin and mediate accelerated effector responses to secondary infection
    1
    1. scibot 29 Dec 2023
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    sciencedirect.com/science/article/pii/S1074761323005009
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    The MHC-E peptide ligands for checkpoint CD94/NKG2A are governed by inflammatory signals, whereas LILRB1/2 receptors are peptide indifferent
    1
    1. scibot 20 Dec 2023
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    sciencedirect.com/science/article/pii/S2211124723015280
  22. Nov 2023
  23. link.springer.com link.springer.com
    Trans-vaccenic acid reprograms CD8+ T cells and anti-tumour immunity
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    1. scibot 25 Nov 2023
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      DOI: 10.1038/s41586-023-06749-3

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    link.springer.com/article/10.1038/s41586-023-06749-3
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    Mice with FVB-derived sequence on chromosome 17 succumb to disseminated virus infection due to aberrant NK cell and T cell responses
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    1. scibot 18 Nov 2023
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      DOI: 10.1016/j.isci.2023.108348

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    sciencedirect.com/science/article/pii/S2589004223024252
  25. Oct 2023
  26. www.sciencedirect.com www.sciencedirect.com
    Genetic and pharmaceutical targeting of HIF1α allows combo-immunotherapy to boost graft vs. leukemia without exacerbation graft vs. host disease
    1
    1. scibot 13 Oct 2023
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      DOI: 10.1016/j.xcrm.2023.101236

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    sciencedirect.com/science/article/pii/S2666379123004135
  27. www.cell.com www.cell.com
    The Transcription Factor IRF4 Determines the Anti-Tumor Immunity of CD8+ T cells
    1
    1. scibot 13 Oct 2023
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      DOI: 10.1016/j.isci.2023.108087

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    cell.com/iscience/abstract/S2589-0042(23)02164-8
  28. www.cell.com www.cell.com
    A micro-electroporation/electrophoresis-based vaccine screening system reveals the impact of vaccination orders on cross-protective immunity
    1
    1. scibot 13 Oct 2023
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    cell.com/iscience/abstract/S2589-0042(23)02163-6
  29. Aug 2023
  30. www.sciencedirect.com www.sciencedirect.com
    Tumor-associated macrophages trigger MAIT cell dysfunction at the HCC invasive margin
    1
    1. scibot 29 Aug 2023
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      DOI: 10.1016/j.cell.2023.07.026

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    sciencedirect.com/science/article/pii/S0092867423008048
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    Endogenous CCL21-Ser deficiency reduces B16–F10 melanoma growth by enhanced antitumor immunity
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    1. scibot 23 Aug 2023
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      DOI: 10.1016/j.heliyon.2023.e19215

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    sciencedirect.com/science/article/pii/S240584402306423X
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    Characterizing CD4 T cell differentiation in mouse small intestine using T cell transfer, lamina propria preparation, and flow cytometry
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      DOI: 10.1016/j.xpro.2023.102485

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    sciencedirect.com/science/article/pii/S2666166723004525
  33. 52.53.155.43 52.53.155.43
    Targeting TCF19 sensitizes MSI endometrial cancer to anti-PD-1 therapy by alleviating CD8+ T cell exhaustion via TRIM14-IFN-β axis
    2
    1. scibot 17 Aug 2023
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    52.53.155.43/f1aa479ee50c1426738d478d555cd8c52a91c49e/PIIS2211124723009555-html.html
  34. Jul 2023
  35. onlinelibrary.wiley.com onlinelibrary.wiley.com
    CCL21-Ser expression in melanoma cells recruits CCR7+ naïve T cells to tumor tissues and promotes tumor growth
    1
    1. scibot 13 Jul 2023
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      DOI: 10.1111/cas.15902

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    onlinelibrary.wiley.com/doi/10.1111/cas.15902
  36. Jun 2023
  37. www.sciencedirect.com www.sciencedirect.com
    Platelets and mast cells promote pathogenic eosinophil recruitment during invasive fungal infection via the 5-HIAA-GPR35 ligand-receptor system
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    1. scibot 07 Jun 2023
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    sciencedirect.com/science/article/pii/S1074761323002236
  38. May 2023
  39. www.sciencedirect.com www.sciencedirect.com
    Cancer-cell-derived fumarate suppresses the anti-tumor capacity of CD8+ T cells in the tumor microenvironment
    1
    1. scibot 13 May 2023
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    sciencedirect.com/science/article/pii/S1550413123001717
  40. link.springer.com link.springer.com
    Co-modulation of TNFR1 and TNFR2 in an animal model of multiple sclerosis
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    1. scibot 02 May 2023
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      DOI: 10.1186/s12974-023-02784-z

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    link.springer.com/article/10.1186/s12974-023-02784-z
  41. Apr 2023
  42. www.sciencedirect.com www.sciencedirect.com
    PSGL-1 attenuates early TCR signaling to suppress CD8+ T cell progenitor differentiation and elicit terminal CD8+ T cell exhaustion
    1
    1. scibot 29 Apr 2023
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      DOI: 10.1016/j.celrep.2023.112436

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    sciencedirect.com/science/article/pii/S2211124723004473
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    T helper 1 effector memory CD4+ T cells protect the skin from poxvirus infection
    1
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    sciencedirect.com/science/article/pii/S2211124723004187
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    Dysregulated lung stroma drives emphysema exacerbation by potentiating resident lymphocytes to suppress an epithelial stem cell reservoir
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    sciencedirect.com/science/article/pii/S1074761323000444
  45. www.sciencedirect.com www.sciencedirect.com
    Spleen fibroblastic reticular cell-derived acetylcholine promotes lipid metabolism to drive autoreactive B cell responses
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    sciencedirect.com/science/article/pii/S1550413123000888
  46. Mar 2023
  47. europepmc.org europepmc.org
    Saturated fatty acids dampen the immunogenicity of cancer by suppressing STING
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    europepmc.org/article/med/36952341
  48. www.sciencedirect.com www.sciencedirect.com
    Endoplasmic reticulum stress in the intestinal epithelium initiates purine metabolite synthesis and promotes Th17 cell differentiation in the gut
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    sciencedirect.com/science/article/pii/S1074761323000924
  49. www.sciencedirect.com www.sciencedirect.com
    TRIB2 safeguards naive T cell homeostasis during aging
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      DOI: 10.1016/j.celrep.2023.112195

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    sciencedirect.com/science/article/pii/S2211124723002061
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    Pyruvate dehydrogenase fuels a critical citrate pool that is essential for Th17 cell effector functions
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      DOI: 10.1016/j.celrep.2023.112153

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    sciencedirect.com/science/article/pii/S221112472300164X
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    Phosphoenolpyruvate regulates the Th17 transcriptional program and inhibits autoimmunity
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      DOI: 10.1016/j.celrep.2023.112205

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    sciencedirect.com/science/article/pii/S2211124723002164
  52. Feb 2023
  53. www.sciencedirect.com www.sciencedirect.com
    The alarmin interleukin-33 promotes the expansion and preserves the stemness of Tcf-1+ CD8+ T cells in chronic viral infection
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    1. scibot 23 Feb 2023
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      DOI: 10.1016/j.immuni.2023.01.029

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    sciencedirect.com/science/article/pii/S1074761323000419
  54. www.sciencedirect.com www.sciencedirect.com
    HMGB1/GPC3 dual targeting vaccine induces dendritic cells-mediated CD8+T cell immune response and elicits potential therapeutic effect in hepatocellular carcinoma
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    1. scibot 17 Feb 2023
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      DOI: 10.1016/j.isci.2023.106143

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  55. Jan 2023
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    Tissue-specific metabolic profile drives iNKT cell function during obesity and liver injury
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    Opioid-induced fragile-like regulatory T cells contribute to withdrawal
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  58. Dec 2022
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    Consumption of fish oil high-fat diet induces murine hair loss via epidermal fatty acid binding protein in skin macrophages
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    RAGE deficiency ameliorates autoimmune hepatitis involving inhibition of IL-6 production via suppressing protein Arid5a in mice
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  61. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Across-cancer immune responses induced by nanovaccines or microvaccines to prevent different cancers and cancer metastasis
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  62. Nov 2022
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    The transcription factor IRF2 drives interferon-mediated CD8+ T cell exhaustion to restrict anti-tumor immunity
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    Obesity enhances antiviral immunity in the genital mucosa through a microbiota-mediated effect on γδ T cells
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  65. Oct 2022
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    Cbl-b Restrains Priming of Pathogenic Th17 Cells via the Inhibition of IL-6 Production by Macrophages
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  67. Sep 2022
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    Ablation of the endoplasmic reticulum stress kinase PERK induces paraptosis and type I interferon to promote anti-tumor T cell responses
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    Balance between immunoregulatory B cells and plasma cells drives pancreatic tumor immunity
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  70. Aug 2022
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    Phospholipid metabolites of the gut microbiota promote hypoxia-induced intestinal injury via CD1d-dependent γδ T cells
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  72. Jul 2022
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    Mucosal chemokine adjuvant enhances synDNA vaccine-mediated responses to SARS-CoV-2 and provides heterologous protection in vivo
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    B cell-mediated regulatory mechanisms control tumor-promoting intestinal inflammation
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  75. May 2022
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    Lymph node colonization induces tumor-immune tolerance to promote distant metastasis
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  77. Apr 2022
  78. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Circular RNA vaccines against SARS-CoV-2 and emerging variants
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  79. Mar 2022
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    Activating Mucosal-Associated Invariant T cells Induces a Broad Antitumor Response
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  81. Feb 2022
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    Balanced T and B cell responses are required for immune protection against Powassan virus in virus-like particle vaccination
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  83. Jan 2022
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    A Bivalent Nanoparticle Vaccine Exhibits Potent Cross-protection against the Variants of SARS-CoV-2
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  85. Dec 2021
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    Nasal prevention of SARS-CoV-2 infection by intranasal influenza-based boost vaccination in mouse models
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    Detection of CD8+ T cell-mediated immune responses to bacterial infection in mice
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    Vectored antibody gene delivery restores host B and T cell control of persistent viral infection
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  89. Nov 2021
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    The allergy mediator histamine confers resistanceto immunotherapy in cancer patients via activationof the macrophage histamine receptor H1
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    Reprogramming NK cells and macrophages via combined antibody and cytokine therapy primes tumors for elimination by checkpoint blockade
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    6-Phosphogluconate dehydrogenase (6PGD), a key checkpoint in reprogramming of regulatory T cells metabolism and function
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    Graded RhoA GTPase Expression in Treg Cells Distinguishes Tumor Immunity From Autoimmunity
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  94. Aug 2021
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  98. Jul 2021
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    Colitis-Induced Th17 Cells Increase the Risk for Severe Subsequent Clostridium difficile Infection
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    An Interleukin-23-Interleukin-22 Axis Regulates Intestinal Microbial Homeostasis to Protect from Diet-Induced Atherosclerosis
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    NKG2A Blockade Potentiates CD8 T Cell Immunity Induced by Cancer Vaccines
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  102. Jun 2021
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    A novel mouse AAV6 hACE2 transduction model of wild-type SARS-CoV-2 infection studied using synDNA immunogens
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    NLRC4 inhibits NLRP3 inflammasome and abrogates effective antifungal CD8+ T cell responses
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    The glutathione peroxidase Gpx4 prevents lipid peroxidation and ferroptosis to sustain Treg cell activation and suppression of antitumor immunity
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    Pro-resolving lipid mediator lipoxin A4 attenuates neuro-inflammation by modulating T cell responses and modifies the spinal cord lipidome
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  107. May 2021
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    Single-Cell RNA Sequencing of Tumor-Infiltrating NK Cells Reveals that Inhibition of Transcription Factor HIF-1α Unleashes NK Cell Activity
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    Fate mapping analysis reveals a novel murine dermal migratory Langerhans-like cell population
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    Recombinant Orthopoxvirus Primes Colon Cancer for Checkpoint Inhibitor and Cross-Primes T Cells for Antitumor and Antiviral Immunity
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    Substance P Release by Sensory Neurons Triggers Dendritic Cell Migration and Initiates the Type-2 Immune Response to Allergens
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  112. Apr 2021
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    Functional Genomics In Vivo Reveal Metabolic Dependencies of Pancreatic Cancer Cells
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    Notch4 signaling limits regulatory T-cell-mediated tissue repair and promotes severe lung inflammation in viral infections
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    UTX promotes CD8+ T cell-mediated antiviral defenses but reduces T cell durability
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  116. Mar 2021
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    Blockade of 6-phosphogluconate dehydrogenase generates CD8+ effector T cells with enhanced anti-tumor function
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  118. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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  119. Feb 2021
  120. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Induction of Progenitor Exhausted Tissue-Resident Memory CD8+ T Cells Upon Salmonella Typhi Porins Adjuvant Immunization Correlates With Melanoma Control and Anti-PD-1 Immunotherapy Cooperation
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  121. www.cell.com www.cell.com
    CD45RB Status of CD8+ T Cell Memory Defines T Cell Receptor Affinity and Persistence
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    Smectite promotes probiotic biofilm formation in the gut for cancer immunotherapy
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  123. www.sciencedirect.com www.sciencedirect.com
    Dynamic adoption of anergy by antigen-exhausted CD4+ T cells
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  124. Dec 2020
  125. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    Nanoparticle Vaccines Based on the Receptor Binding Domain (RBD) and Heptad Repeat (HR) of SARS-CoV-2 Elicit Robust Protective Immune Responses
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  126. Nov 2020
  127. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Induction of Progenitor Exhausted Tissue-Resident Memory CD8+ T Cells Upon Salmonella Typhi Porins Adjuvant Immunization Correlates With Melanoma Control and Anti-PD-1 Immunotherapy Cooperation
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  128. Sep 2020
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    Type I Interferons Suppress Anti-parasitic Immunity and Can Be Targeted to Improve Treatment of Visceral Leishmaniasis
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  130. www.cell.com www.cell.com
    CD45RB Status of CD8+ T Cell Memory Defines T Cell Receptor Affinity and Persistence
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  131. www.sciencedirect.com www.sciencedirect.com
    The PD-1 Pathway Regulates Development and Function of Memory CD8+ T Cells following Respiratory Viral Infection
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    Glutathione Restricts Serine Metabolism to Preserve Regulatory T Cell Function
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  133. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Quantitative analysis of how Myc controls T cell proteomes and metabolic pathways during T cell activation
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  134. www.sciencedirect.com www.sciencedirect.com
    High Dimensional Single-Cell Analysis Reveals iNKT Cell Developmental Trajectories and Effector Fate Decision
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    FOXD3 Regulates VISTA Expression in Melanoma
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    Cyclopentenone Prostaglandins and Structurally Related Oxidized Lipid Species Instigate and Share Distinct Pro- and Anti-inflammatory Pathways
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  137. www.sciencedirect.com www.sciencedirect.com
    Neutrophil Caspase-11 Is Essential to Defend against a Cytosol-Invasive Bacterium
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  138. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Thioredoxin-1 distinctly promotes NF-κB target DNA binding and NLRP3 inflammasome activation independently of Txnip
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  139. Jan 2020
  140. www.sciencedirect.com www.sciencedirect.com
    Defects in Antiviral T Cell Responses Inflicted by Aging-Associated miR-181a Deficiency
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    Restricting Glycolysis Preserves T Cell Effector Functions and Augments Checkpoint Therapy
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    Salmonella-Driven Polarization of Granuloma Macrophages Antagonizes TNF-Mediated Pathogen Restriction during Persistent Infection
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      DOI: 10.1016/j.chom.2019.11.011

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  143. www.sciencedirect.com www.sciencedirect.com
    IL-10-Dependent Crosstalk between Murine Marginal Zone B Cells, Macrophages, and CD8α+ Dendritic Cells Promotes Listeria monocytogenes Infection
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  144. www.sciencedirect.com www.sciencedirect.com
    Systematic Immunotherapy Target Discovery Using Genome-Scale In Vivo CRISPR Screens in CD8 T Cells
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      DOI: 10.1016/j.cell.2019.07.044

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  145. www.sciencedirect.com www.sciencedirect.com
    Pharmacological Activation of Pyruvate Kinase M2 Inhibits CD4+ T Cell Pathogenicity and Suppresses Autoimmunity
    1
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    Proliferating Transitory T Cells with an Effector-like Transcriptional Signature Emerge from PD-1+ Stem-like CD8+ T Cells during Chronic Infection
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    Quantitative Difference in PLZF Protein Expression Determines iNKT Lineage Fate and Controls Innate CD8 T Cell Generation
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  148. www.sciencedirect.com www.sciencedirect.com
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    Colitis-Induced Th17 Cells Increase the Risk for Severe Subsequent Clostridium difficile Infection
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      DOI: 10.1016/j.chom.2019.03.003

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  152. Nov 2018
  153. www-sciencedirect-com.ezproxy.is.ed.ac.uk www-sciencedirect-com.ezproxy.is.ed.ac.uk
    CD8+ T Cell Priming in Established Chronic Viral Infection Preferentially Directs Differentiation of Memory-like Cells for Sustained Immunity
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  154. www.sciencedirect.com www.sciencedirect.com
    Blimp-1 Functions as a Molecular Switch to Prevent Inflammatory Activity in Foxp3+RORγt+ Regulatory T Cells
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    SYK-CARD9 Signaling Axis Promotes Gut Fungi-Mediated Inflammasome Activation to Restrict Colitis and Colon Cancer
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    Th9 Cells Represent a Unique Subset of CD4+ T Cells Endowed with the Ability to Eradicate Advanced Tumors
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    Dietary Fiber Confers Protection against Flu by Shaping Ly6c− Patrolling Monocyte Hematopoiesis and CD8+ T Cell Metabolism
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    Tumor-Repopulating Cells Induce PD-1 Expression in CD8+ T Cells by Transferring Kynurenine and AhR Activation
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    KLRG1+ Effector CD8+ T Cells Lose KLRG1, Differentiate into All Memory T Cell Lineages, and Convey Enhanced Protective Immunity
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    1. scibot 05 Nov 2018
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    sciencedirect.com/science/article/pii/S1074761318300918
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    Interleukin-10 Directly Inhibits CD8+ T Cell Function by Enhancing N-Glycan Branching to Decrease Antigen Sensitivity
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    1. scibot 05 Nov 2018
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      Curator: @Jmenke

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    sciencedirect.com/science/article/pii/S1074761318300062
  161. academic.oup.com academic.oup.com
    Untitled document
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    1. scibot 05 Nov 2018
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    academic.oup.com/endo/article/158/10/3140/4060086
  162. europepmc.org europepmc.org
    Crucial role for T cell-intrinsic IL-18R-MyD88 signaling in cognate immune response to intracellular parasite infection.
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    1. scibot 05 Nov 2018
      RRID:AB_315404

      Curator: @evieth

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    europepmc.org/articles/PMC5629024/
  163. Nov 2017
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    Enhancing CD8+ T Cell Fatty Acid Catabolism within a Metabolically Challenging Tumor Microenvironment Increases the Efficacy of Melanoma Immunotherapy
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    1. scibot 08 Nov 2017
      RRID:AB_315404

      Curator: @Jmenke

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    sciencedirect.com/science/article/pii/S1535610817303471