Hypothesis

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Aug 2025
52.53.155.43 52.53.155.43

1-s2.0-S2589004225016621-main-html.html

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1. scibot 20 Aug 2025
  
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  DOI: 10.1016/j.isci.2025.113401
  
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52.53.155.43/95de129ed366fdde12a3301c0abc97c56a41c6b6/1-s2.0-S2589004225016621-main-html.html
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Abstinence from cocaine self-administration promotes microglial pruning of astrocytes, which drives cocaine-seeking behavior

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1. scibot 13 Aug 2025
  
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  DOI: 10.1016/j.celrep.2025.116137
  
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sciencedirect.com/science/article/pii/S2211124725009088
May 2025
52.53.155.43 52.53.155.43

1-s2.0-S1525001625003806-main-html.html

1
1. scibot 19 May 2025
  
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  DOI: 10.1016/j.ymthe.2025.05.010
  
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52.53.155.43/1f8027de8a77cdc6b8dd6c2280a8a83083808fa3/1-s2.0-S1525001625003806-main-html.html
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Activity-dependent degradation of Kv4.2 contributes to synaptic plasticity and behavior in Angelman syndrome model mice

1
1. scibot 16 May 2025
  
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  DOI: 10.1016/j.celrep.2025.115583
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12232208/
Apr 2025
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ARC/ARG3.1 binds the nuclear polyadenylate-binding protein RRM and regulates neuronal activity-dependent formation of nuclear speckles

1
1. scibot 15 Apr 2025
  
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  DOI: 10.1016/j.celrep.2025.115525
  
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sciencedirect.com/science/article/pii/S2211124725002967
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Heparan Sulfate Organizes Neuronal Synapses through Neurexin Partnerships

1
1. scibot 09 Apr 2025
  
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  DOI: 10.1016/j.cell.2018.07.002
  
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pmc.ncbi.nlm.nih.gov/articles/PMC6173057/
Mar 2025
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Astrocyte glypican 5 regulates synapse maturation and stabilization

1
1. scibot 06 Mar 2025
  
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  DOI: 10.1016/j.celrep.2025.115374
  
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sciencedirect.com/science/article/pii/S2211124725001457
Feb 2025
www.jneurosci.org www.jneurosci.org

Metabotropic NMDAR Signaling Contributes to Sex Differences in Synaptic Plasticity and Episodic Memory

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1. scibot 27 Feb 2025
  
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  DOI: 10.1523/JNEUROSCI.0438-24.2024
  
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jneurosci.org/content/44/50/e0438242024
www.jneurosci.org www.jneurosci.org

Phospholipid Scramblase 1 Controls Efficient Neurotransmission and Synaptic Vesicle Retrieval at Cerebellar Synapses

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1. scibot 27 Feb 2025
  
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  DOI: 10.1523/JNEUROSCI.0042-24.2024
  
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jneurosci.org/content/44/27/e0042242024
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Imaging lipid rafts reveals the principle of ApoE4-induced Aβ upregulation in human neurons

1
1. scibot 11 Feb 2025
  
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  DOI: 10.1016/j.isci.2025.111893
  
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sciencedirect.com/science/article/pii/S2589004225001531
Dec 2024
onlinelibrary.wiley.com onlinelibrary.wiley.com

Hierarchical organisation and genetically separable subfamilies of PSD95 postsynaptic supercomplexes

1
1. scibot 05 Dec 2024
  
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  DOI: 10.1111/jnc.14056
  
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onlinelibrary.wiley.com/doi/10.1111/jnc.14056
Oct 2024
www.nature.com www.nature.com

Dysregulation of miRNA expression and excitation in MEF2C autism patient hiPSC-neurons and cerebral organoids

1
1. scibot 04 Oct 2024
  
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  DOI: 10.1038/s41380-024-02761-9
  
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nature.com/articles/s41380-024-02761-9
Sep 2024
www.sciencedirect.com www.sciencedirect.com

Uncoupling the CRMP2-CaV2.2 interaction reduces pain-like behavior in a preclinical joint-pain model

1
1. scibot 04 Sep 2024
  
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  DOI: 10.1016/j.jpain.2024.104664
  
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sciencedirect.com/science/article/pii/S1526590024006205
Jul 2024
onlinelibrary.wiley.com onlinelibrary.wiley.com

Astrocytes facilitate gabazine-evoked electrophysiological hyperactivity and distinct biochemical responses in mature neuronal cultures

1
1. scibot 18 Jul 2024
  
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  DOI: 10.1111/jnc.16182
  
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onlinelibrary.wiley.com/doi/10.1111/jnc.16182
www.biorxiv.org www.biorxiv.org

Immune Checkpoint Inhibition-related Neuroinflammation Disrupts Cognitive Function

1
1. scibot 16 Jul 2024
  
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  DOI: 10.1101/2024.07.01.601087
  
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biorxiv.org/content/10.1101/2024.07.01.601087v1
www.biorxiv.org www.biorxiv.org

RNAi-mediated silencing of SOD1 profoundly extends survival and functional outcomes in ALS mice

1
1. scibot 04 Jul 2024
  
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  DOI: 10.1101/2024.06.20.599943
  
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biorxiv.org/content/10.1101/2024.06.20.599943v1
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Uncoupling the CRMP2-CaV2.2 interaction reduces pain-like behavior in a preclinical osteoarthritis model

1
1. scibot 03 Jul 2024
  
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  DOI: 10.1101/2024.06.05.596514
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11185632/
Feb 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Metabotropic NMDA Receptor Signaling Contributes to Sex Differences in Synaptic Plasticity and Episodic Memory

1
1. scibot 16 Feb 2024
  
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  AB_325399
  
  DOI: 10.1101/2024.01.26.577478
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10849651/
Jan 2024
www.science.org www.science.org

Integration of reconfigurable microchannels into aligned three-dimensional neural networks for spatially controllable neuromodulation

1
1. scibot 18 Jan 2024
  
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  DOI: 10.1126/sciadv.adf0925
  
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science.org/doi/10.1126/sciadv.adf0925
Nov 2023
www.sciencedirect.com www.sciencedirect.com

Microglial Rac1 is essential for experience-dependent brain plasticity and cognitive performance

1
1. scibot 28 Nov 2023
  
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  DOI: 10.1016/j.celrep.2023.113447
  
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sciencedirect.com/science/article/pii/S2211124723014596
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Engram cell connectivity as a mechanism for information encoding and memory function

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1. scibot 22 Nov 2023
  
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  DOI: 10.1016/j.cub.2023.10.074
  
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sciencedirect.com/science/article/abs/pii/S0960982223015129
Oct 2023
www.biorxiv.org www.biorxiv.org

Parkinson’s-linked LRRK2-G2019S derails AMPAR trafficking, mobility and composition in striatum with cell-type and subunit specificity

1
1. scibot 24 Oct 2023
  
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  DOI: 10.1101/2023.10.13.562231
  
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biorxiv.org/content/10.1101/2023.10.13.562231v1
Aug 2023
52.53.155.43 52.53.155.43

Repeated mild traumatic brain injury triggers pathology in asymptomatic C9ORF72 transgenic mice

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1. scibot 04 Aug 2023
  
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  DOI: 10.1093/brain/awad264
  
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52.53.155.43/5178e3b5a29ba09ab2106f8993d42d5e0411ae62/awad264 (1)-html.html
Jul 2023
www.sciencedirect.com www.sciencedirect.com

Alternative splicing and heparan sulfation converge on neurexin-1 to control glutamatergic transmission and autism-related behaviors

1
1. scibot 05 Jul 2023
  
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  DOI: 10.1016/j.celrep.2023.112714
  
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sciencedirect.com/science/article/pii/S2211124723007258
Jun 2023
onlinelibrary.wiley.com onlinelibrary.wiley.com

Astrotactin2 (ASTN2) regulates emotional and cognitive functions by affecting neuronal morphogenesis and monoaminergic systems

1
1. scibot 01 Jun 2023
  
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  DOI: 10.1111/jnc.15790
  
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onlinelibrary.wiley.com/doi/10.1111/jnc.15790
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

A Neuroligin-1 mutation associated with Alzheimer’s disease produces memory and age-dependent impairments in hippocampal plasticity

1
1. scibot 01 Jun 2023
  
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  DOI: 10.1016/j.isci.2023.106868
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10227424/
Apr 2023
www.sciencedirect.com www.sciencedirect.com

Interhemispheric cortical long-term potentiation in the auditory cortex requires heterosynaptic activation of entorhinal projection

1
1. scibot 25 Apr 2023
  
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  DOI: 10.1016/j.isci.2023.106542
  
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sciencedirect.com/science/article/pii/S2589004223006193
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

The developmental sequence of the dendritic spine and synapse maturation in transcription factor-induced human iPSC-derived neurons

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1. scibot 12 Apr 2023
  
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  DOI: 10.1016/j.isci.2023.106285
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10073939/
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γ-Protocadherins control synapse formation and peripheral branching of touch sensory neurons

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1. scibot 07 Apr 2023
  
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  DOI: 10.1016/j.neuron.2023.03.012
  
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sciencedirect.com/science/article/pii/S0896627323002088
Mar 2023
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Altered striatal actin dynamics drives behavioral inflexibility in a mouse model of fragile X syndrome

1
1. scibot 30 Mar 2023
  
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  DOI: 10.1016/j.neuron.2023.03.008
  
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sciencedirect.com/science/article/pii/S0896627323002040
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Integration of reconfigurable microchannels into aligned three-dimensional neural networks for spatially controllable neuromodulation

1
1. scibot 13 Mar 2023
  
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  RRID:AB_325399
  
  DOI: 10.1126/sciadv.adf0925
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10005277/
Feb 2023
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Neuroprotective Effects of a Multi-Herbal Extract on Axonal and Synaptic Disruption in Vitro and Cognitive Impairment in Vivo

1
1. scibot 15 Feb 2023
  
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  DOI: 10.3233/ADR-220056
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9912829/
Jan 2023
www.sciencedirect.com www.sciencedirect.com

Excitation-inhibition imbalance disrupts visual familiarity in amyloid and non-pathology conditions

1
1. scibot 26 Jan 2023
  
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  DOI: 10.1016/j.celrep.2022.111946
  
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sciencedirect.com/science/article/pii/S2211124722018472
Nov 2022
www.nature.com www.nature.com

R1441C and G2019S LRRK2 knockin mice have distinct striatal molecular, physiological, and behavioral alterations

1
1. scibot 15 Nov 2022
  
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  RRID:AB_325399
  
  DOI: 10.1038/s42003-022-04136-8
  
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nature.com/articles/s42003-022-04136-8
Oct 2022
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Diverging Effects of Adolescent Ethanol Exposure on Tripartite Synaptic Development across Prefrontal Cortex Subregions

1
1. scibot 26 Oct 2022
  
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  RRID:AB_325399
  
  DOI: 10.3390/cells11193111
  
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Downregulation of surface AMPA receptor expression in the striatum following prolonged social isolation, a role of mGlu5 receptors

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Synaptic loss in a mouse model of euthyroid Hashimoto’s thyroiditis: possible involvement of the microglia

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Endosomal phosphatidylinositol 3-phosphate controls synaptic vesicle cycling and neurotransmission

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Prepubescent female rodents have enhanced hippocampal LTP and learning relative to males, reversing in adulthood as inhibition increases

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Early postnatal inhibition of GLAST causes abnormalities of psychobehaviors and neuronal morphology in adult mice

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Long-Lasting Changes in Glial Cells Isolated From Rats Subjected to the Valproic Acid Model of Autism Spectrum Disorder

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Stimulus evoked ERK-dependent phosphorylation of activity-regulated cytoskeleton-associated protein (Arc) regulates its neuronal subcellular localization

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Functional Consequences of Synapse Remodeling Following Astrocyte-Specific Regulation of Ephrin-B1 in the Adult Hippocampus

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PSD-95 protects synapses from β-amyloid

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Shootin1a-mediated actin-adhesion coupling generates force to trigger structural plasticity of dendritic spines

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Neuroligin-1-Modified Electrodes for Specific Coupling with a Presynaptic Neuronal Membrane

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Hippocampal neurons isolated from rats subjected to the valproic acid model mimic in vivo synaptic pattern: evidence of neuronal priming during early development in autism spectrum disorders

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Pathway-specific dysregulation of striatal excitatory synapses by LRRK2 mutations

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Rescuing Over-activated Microglia Restores Cognitive Performance in Juvenile Animals of the Dp(16) Mouse Model of Down Syndrome

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Cyclin Y, a novel actin-binding protein, regulates spine plasticity through the cofilin-actin pathway

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Microglia Dysfunction Caused by the Loss of Rhoa Disrupts Neuronal Physiology and Leads to Neurodegeneration

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Astrocytic ephrin-B1 controls excitatory-inhibitory balance in developing hippocampus

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Astrocytic Ephrin-B1 Controls Synapse Formation in the Hippocampus During Learning and Memory

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LRRTMs Organize Synapses through Differential Engagement of Neurexin and PTPσ

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High‐Resolution Three‐Dimensional Imaging of Individual Astrocytes Using Confocal Microscopy

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The LMTK1—TBC1D9B—Rab11A cascade regulates dendritic spine formation via endosome trafficking

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UBE3A-mediated p18/LAMTOR1 ubiquitination and degradation regulate mTORC1 activity and synaptic plasticity

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17α Estradiol promotes plasticity of spared inputs in the adult amblyopic visual cortex

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Distinct Pathogenic Genes Causing Intellectual Disability and Autism Exhibit a Common Neuronal Network Hyperactivity Phenotype

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Selective rab11 transport and the intrinsic regenerative ability of CNS axons

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Modeling a Neurexin-3α human mutation in mouse neurons identifies a novel role in the regulation of transsynaptic signaling and neurotransmitter release at excitatory synapses

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Functional Consequences of Synapse Remodeling Following Astrocyte-Specific Regulation of Ephrin-B1 in the Adult Hippocampus

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Csmd2 Is a Synaptic Transmembrane Protein that Interacts with PSD-95 and Is Required for Neuronal Maturation

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eneuro.org/content/6/2/ENEURO.0434-18.2019
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1. scibot 12 Jan 2020
  
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  AB_325399
  
  DOI: 10.1016/j.neuroscience.2019.02.021
  
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  Curator: @ethanbadger
  
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sciencedirect.com/science/article/pii/S030645221930123X
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1. scibot 12 Jan 2020
  
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  RRID:AB_325399
  
  DOI: 10.1016/j.neuron.2018.12.036
  
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  Curator: @ethanbadger
  
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sciencedirect.com/science/article/pii/S0896627318311565
Nov 2018
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Astrocyte-Secreted Chordin-like 1 Drives Synapse Maturation and Limits Plasticity by Increasing Synaptic GluA2 AMPA Receptors

1
1. scibot 05 Nov 2018
  
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  RRID:AB_325399
  
  Curator: @Jmenke
  
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  (Thermo Fisher Scientific Cat# MA1-045, RRID:AB_325399)
  
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sciencedirect.com/science/article/pii/S0896627318308456
www.jneurosci.org www.jneurosci.org

Memory-Related Synaptic Plasticity Is Sexually Dimorphic in Rodent Hippocampus

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1. scibot 05 Nov 2018
  
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  RRID:AB_325399
  
  Curator: @evieth
  
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  (Thermo Fisher Scientific Cat# MA1-045, RRID:AB_325399)
  
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jneurosci.org/content/38/37/7935
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Heparan Sulfate Organizes Neuronal Synapses through Neurexin Partnerships

1
1. scibot 05 Nov 2018
  
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  RRID:AB_325399
  
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  (Thermo Fisher Scientific Cat# MA1-045, RRID:AB_325399)
  
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pmc.ncbi.nlm.nih.gov/articles/PMC6173057/
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1. scibot 05 Nov 2018
  
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  RRID:AB_325399
  
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  (Thermo Fisher Scientific Cat# MA1-045, RRID:AB_325399)
  
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ncbi.nlm.nih.gov/pmc/articles/PMC6063731/
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Astrocyte-Secreted Glypican 4 Regulates Release of Neuronal Pentraxin 1 from Axons to Induce Functional Synapse Formation

1
1. scibot 05 Nov 2018
  
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  RRID:AB_325399
  
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  (Thermo Fisher Scientific Cat# MA1-045, RRID:AB_325399)
  
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sciencedirect.com/science/article/pii/S0896627317309224
europepmc.org europepmc.org

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  RRID:AB_325399
  
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  (Thermo Fisher Scientific Cat# MA1-045, RRID:AB_325399)
  
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europepmc.org/articles/PMC5601282/
Nov 2017
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Amyloid Beta Peptides Block New Synapse Assembly by Nogo Receptor-Mediated Inhibition of T-Type Calcium Channels

1
1. scibot 08 Nov 2017
  
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  RRID:AB_325399
  
  Curator: @Jmenke
  
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  (Thermo Fisher Scientific Cat# MA1-045, RRID:AB_325399)
  
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sciencedirect.com/science/article/pii/S0896627317309108
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AMPA receptors at ribbon synapses in the mammalian retina: kinetic models and molecular identity

1
1. scibot 08 Nov 2017
  
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  AB_325399
  
  Curator: @patriciaelyse_
  
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  (Thermo Fisher Scientific Cat# MA1-045, RRID:AB_325399)
  
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link.springer.com/article/10.1007/s00429-017-1520-1
onlinelibrary.wiley.com onlinelibrary.wiley.com

Hierarchical organisation and genetically separable subfamilies of PSD95 postsynaptic supercomplexes

1
1. scibot 08 Nov 2017
  
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  RRID:AB_325399
  
  Curator: @patriciaelyse_
  
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onlinelibrary.wiley.com/doi/10.1111/jnc.14056
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1. scibot 08 Nov 2017
  
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  AB_325399
  
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  (Thermo Fisher Scientific Cat# MA1-045, RRID:AB_325399)
  
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academic.oup.com/cercor/article/3829386/Atypical-Endocannabinoid-Signaling-Initiates-a-New
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Stimulus evoked ERK-dependent phosphorylation of activity-regulated cytoskeleton-associated protein (Arc) regulates its neuronal subcellular localization

1
1. scibot 08 Nov 2017
  
  in Public
  
  mouse anti-PSD 95 (Thermo Scientific MA1-045; Antibody Registry: AB_325399
  
  Curator: @bandrow
  
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sciencedirect.com/science/article/pii/S0306452217304967
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Atypical Endocannabinoid Signaling Initiates a New Form of Memory-Related Plasticity at a Cortical Input to Hippocampus

1
1. scibot 08 Nov 2017
  
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  AB_325399
  
  Curator: @bandrow
  
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  (Thermo Fisher Scientific Cat# MA1-045, RRID:AB_325399)
  
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academic.oup.com/cercor/article/doi/10.1093/cercor/bhx126/3829386/Atypical-Endocannabinoid-Signaling-Initiates-a-New
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Transient oxytocin signaling primes the development and function of excitatory hippocampal neurons

1
1. scibot 08 Nov 2017
  
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  AB_325399
  
  Curator: @kaitlinsung
  
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ncbi.nlm.nih.gov/pmc/articles/PMC5323041/
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An Unbiased Expression Screen for Synaptogenic Proteins Identifies the LRRTM Protein Family as Synaptic Organizers

1
1. scibot 08 Nov 2017
  
  in Public
  
  anti-PSD-95 family (IgG2a; 1:500; clone 6G6-1C9; Affinity Bioreagents; recognizes PSD-95, PSD-93, SAP102 and SAP97)
  
  Curator: @Annap2
  
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  (Thermo Fisher Scientific Cat# MA1-045, RRID:AB_325399)
  
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ncbi.nlm.nih.gov/pmc/articles/PMC2746109/

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