503 Matching Annotations
  1. Sep 2021
  2. www.sciencedirect.com www.sciencedirect.com
    KARATE: PKA-induced KRAS4B-RHOA-mTORC2 supercomplex phosphorylates AKT in insulin signaling and glucose homeostasis
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    1. scibot 22 Sep 2021
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      DOI: 10.1016/j.molcel.2021.09.001

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    sciencedirect.com/science/article/pii/S1097276521007358
  3. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Complement Factor B Mediates Ocular Angiogenesis through Regulating the VEGF Signaling Pathway
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    1. scibot 14 Sep 2021
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      DOI: 10.3390/ijms22179580

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    ncbi.nlm.nih.gov/pmc/articles/PMC8431595/
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    Cilium induction triggers differentiation of glioma stem cells
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      DOI: 10.1016/j.celrep.2021.109656

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    sciencedirect.com/science/article/pii/S2211124721010998
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    C1q/tumor necrosis factor-related protein-3 improves microvascular endothelial function in diabetes through the AMPK/eNOS/NO· signaling pathway
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    1. scibot 04 Sep 2021
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      DOI: 10.1016/j.bcp.2021.114745

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    sciencedirect.com/science/article/pii/S0006295221003610
  6. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Establishment and genetic characterization of cell lines derived from proliferating nasal polyps and sinonasal inverted papillomas
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    1. scibot 03 Sep 2021
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      DOI: 10.1038/s41598-021-96444-y

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    ncbi.nlm.nih.gov/pmc/articles/PMC8384845/
  7. Aug 2021
  8. www.sciencedirect.com www.sciencedirect.com
    CD63-mediated cloaking of VEGF in small extracellular vesicles contributes to anti-VEGF therapy resistance
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    1. scibot 18 Aug 2021
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      DOI: 10.1016/j.celrep.2021.109549

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    sciencedirect.com/science/article/pii/S2211124721009839
  9. academic.oup.com academic.oup.com
    IL6/sIL-6Rα trans-signaling increases PGE2 production in human granulosa cells
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    1. scibot 16 Aug 2021
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      DOI: 10.1093/biolre/ioab128

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    academic.oup.com/biolreprod/advance-article/doi/10.1093/biolre/ioab128/6312586
  10. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    AMPK ACTIVATION AMELIORATES KIDNEY VASCULAR DYSFUNCTION, OXIDATIVE STRESS AND INFLAMMATION IN OBESITY
    1
    1. scibot 16 Aug 2021
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      DOI: 10.1111/bph.15600

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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.15600
  11. www.physiology.org www.physiology.org
    Energy metabolism couples hepatocyte integrin-linked kinase to liver glucoregulation and postabsorptive responses of mice in an age-dependent manner
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    1. scibot 14 Aug 2021
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      DOI: 10.1152/ajpendo.00496.2018

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    physiology.org/doi/abs/10.1152/ajpendo.00496.2018
  12. academic.oup.com academic.oup.com
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    1. scibot 13 Aug 2021
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      DOI: 10.1210/jc.2018-01573

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    academic.oup.com/jcem/article/104/6/2041/5239680
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    ncbi.nlm.nih.gov/pmc/articles/PMC5659703/
  14. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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    1. scibot 12 Aug 2021
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    ncbi.nlm.nih.gov/pmc/articles/PMC5659665/
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    ncbi.nlm.nih.gov/pmc/articles/PMC6286653/
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    ncbi.nlm.nih.gov/pmc/articles/PMC6333918/
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      DOI: 10.1016/j.cmet.2018.11.006

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    sciencedirect.com/science/article/pii/S1550413118306831
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    sciencedirect.com/science/article/pii/S2352396418304808
  19. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Sex Differences in the Rapid Cell Signaling Mechanisms Underlying the Memory-Enhancing Effects of 17β-Estradiol
    1
    1. scibot 08 Aug 2021
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      DOI: 10.1523/ENEURO.0267-18.2018

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    ncbi.nlm.nih.gov/pmc/articles/PMC6220582/
  20. academic.oup.com academic.oup.com
    β-Catenin Directs Long-Chain Fatty Acid Catabolism in the Osteoblasts of Male Mice
    1
    1. scibot 08 Aug 2021
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      DOI: 10.1210/en.2017-00850

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    academic.oup.com/endo/article/159/1/272/4565485
  21. academic.oup.com academic.oup.com
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      AB_329825

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    academic.oup.com/endo/article/158/9/2944/3896894
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    Resistance to Epigenetic-Targeted Therapy Engenders Tumor Cell Vulnerabilities Associated with Enhancer Remodeling
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    1. scibot 04 Aug 2021
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      DOI: 10.1016/j.ccell.2018.11.005

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    sciencedirect.com/science/article/pii/S1535610818305269
  23. academic.oup.com academic.oup.com
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    academic.oup.com/endo/article/158/10/3647/4080743
  24. academic.oup.com academic.oup.com
    Gestational Diabetes Epigenetically Reprograms the Cart Promoter in Fetal Ovary, Causing Subfertility in Adult Life
    1
    1. scibot 03 Aug 2021
      RRID:AB_329825

      DOI: 10.1210/en.2019-00319

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    academic.oup.com/endo/article/160/7/1684/5506444
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    academic.oup.com/endo/article/158/6/1898/3074049
  26. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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      DOI: 10.1016/j.stem.2018.05.003

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    ncbi.nlm.nih.gov/pmc/articles/PMC5988582/
  27. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    AhR ligand aminoflavone suppresses α6‐integrin–Src–Akt signaling to attenuate tamoxifen resistance in breast cancer cells
    1
    1. scibot 02 Aug 2021
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      DOI: 10.1002/jcp.27013

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    ncbi.nlm.nih.gov/pmc/articles/PMC6202151/
  28. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Context Specificity in Causal Signaling Networks Revealed by Phosphoprotein Profiling
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      DOI: 10.1016/j.cels.2016.11.013

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    ncbi.nlm.nih.gov/pmc/articles/PMC5279869/
  29. onlinelibrary.wiley.com onlinelibrary.wiley.com
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      DOI: 10.1111/jnc.14238

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    onlinelibrary.wiley.com/doi/full/10.1111/jnc.14238
  30. www.mdpi.com www.mdpi.com
    CRISPR/Cas9-Mediated Knock-Out of KrasG12D Mutated Pancreatic Cancer Cell Lines
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    1. scibot 02 Aug 2021
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      DOI: 10.3390/ijms20225706

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    mdpi.com/1422-0067/20/22/5706
  31. academic.oup.com academic.oup.com
    Lithium Chloride Increases COX-2 Expression and PGE2 Production in a Human Granulosa-Lutein SVOG Cell Line Via a GSK-3β/β-Catenin Signaling Pathway
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    1. scibot 02 Aug 2021
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    academic.oup.com/endo/article/158/9/2813/3956591
  32. elifesciences.org elifesciences.org
    PPM1H phosphatase counteracts LRRK2 signaling by selectively dephosphorylating Rab proteins
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      DOI: 10.7554/eLife.50416

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    elifesciences.org/articles/50416
  33. Jul 2021
  34. www.jlr.org www.jlr.org
    Identification of ApoA4 as a sphingosine 1-phosphate chaperone in ApoM- and albumin-deficient mice
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    1. scibot 31 Jul 2021
      anti-phospho Akt

      DOI: 10.1194/jlr.RA119000277

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  35. www.sciencedirect.com www.sciencedirect.com
    Dysregulation of Mitochondrial Ca2+ Uptake and Sarcolemma Repair Underlie Muscle Weakness and Wasting in Patients and Mice Lacking MICU1
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      Rabbit anti-phospho-AKT (Ser473)

      DOI: 10.1016/j.celrep.2019.09.063

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    sciencedirect.com/science/article/pii/S2211124719312604
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    academic.oup.com/endo/article/160/2/430/5262410
  37. academic.oup.com academic.oup.com
    Intrinsic High Aerobic Capacity in Male Rats Protects Against Diet-Induced Insulin Resistance
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      DOI: 10.1210/en.2019-00118

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    Regulation of the Elongation Phase of Protein Synthesis Enhances Translation Accuracy and Modulates Lifespan
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      DOI: 10.1016/j.cub.2019.01.029

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    sciencedirect.com/science/article/pii/S0960982219300314
  39. www.sciencedirect.com www.sciencedirect.com
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    sciencedirect.com/science/article/pii/S2211124719301767
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      DOI: 10.1210/en.2018-00531

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  41. www.sciencedirect.com www.sciencedirect.com
    12-Lipoxygenase Regulates Cold Adaptation and Glucose Metabolism by Producing the Omega-3 Lipid 12-HEPE from Brown Fat
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      Phospho-Akt (Ser473)

      DOI: 10.1016/j.cmet.2019.07.001

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    sciencedirect.com/science/article/pii/S1550413119303742
  42. mbio.asm.org mbio.asm.org
    Pathogenic Escherichia coli Hijacks GTPase-Activated p21-Activated Kinase for Actin Pedestal Formation
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    1. scibot 29 Jul 2021
      phospho-Akt [Ser473], 9271

      DOI: 10.1128/mBio.01876-19

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    mbio.asm.org/content/10/4/e01876-19
  43. www.sciencedirect.com www.sciencedirect.com
    Pro-Survival Lipid Sphingosine-1-Phosphate Metabolically Programs T Cells to Limit Anti-tumor Activity
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      Mouse anti-Akt (pS473)

      DOI: 10.1016/j.celrep.2019.07.044

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    sciencedirect.com/science/article/pii/S2211124719309416
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    PI3K inhibitors protect against glucocorticoid-induced skin atrophy
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    sciencedirect.com/science/article/pii/S2352396419300428
  45. academic.oup.com academic.oup.com
    Lack of Lrp5 Signaling in Osteoblasts Sensitizes Male Mice to Diet-Induced Disturbances in Glucose Metabolism
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    Lithium Chloride Increases COX-2 Expression and PGE2 Production in a Human Granulosa-Lutein SVOG Cell Line Via a GSK-3β/β-Catenin Signaling Pathway
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  47. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Context Specificity in Causal Signaling Networks Revealed by Phosphoprotein Profiling
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    Low-Dose Dihydrotestosterone Drives Metabolic Dysfunction via Cytosolic and Nuclear Hepatic Androgen Receptor Mechanisms
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      Phospho-AKTu00a0u00a0p-AKT (Ser473)u00a0Cell Signaling Technology, no. 9271u00a0Rabbit; polyclonalu00a0

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  49. press.endocrine.org press.endocrine.org
    Nervous System Expression of PPARγ and Mutant PPARγ Has Profound Effects on Metabolic Regulation and Brain Development: Endocrinology: Vol 157, No 11
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    AhR ligand aminoflavone suppresses α6‐integrin–Src–Akt signaling to attenuate tamoxifen resistance in breast cancer cells
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    A Novel Small Molecule GDNF Receptor RET Agonist, BT13, Promotes Neurite Growth from Sensory Neurons in Vitro and Attenuates Experimental Neuropathy in the Rat.
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    Modulation of Akt vs Stat3 activity by the focal adhesion kinase in non-neoplastic mouse fibroblasts
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    Extracellular domain shedding of the ALK receptor mediates neuroblastoma cell migration
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    Doxorubicin induces dysregulation of AMPA receptor and impairs hippocampal synaptic plasticity leading to learning and memory deficits
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    Pancreatic fat cells of humans with type 2 diabetes display reduced adipogenic and lipolytic activity | American Journal of Physiology-Cell Physiology
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    Endothelial insulin receptors promote VEGF-A signaling via ERK1/2 and sprouting angiogenesis
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    CX3CL1–CX3CR1 signalling deficiency exacerbates obesity-induced inflammation and insulin resistance in male mice
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    Pancreatic fat cells of humans with type 2 diabetes display reduced adipogenic and lipolytic activity
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    Co-occurring gain-of-function mutations in HER2 and HER3 modulate HER2/HER3 activation, oncogenesis, and HER2 inhibitor sensitivity
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  67. faseb.onlinelibrary.wiley.com faseb.onlinelibrary.wiley.com
    Palmitic acid induces insulin resistance by a mechanism associated with energy metabolism and calcium entry in neuronal cells
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    The CD44/COL17A1 pathway promotes the formation of multilayered, transformed epithelia
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    PD-L1 recruits phospholipase C and enhances tumorigenicity of lung tumors harboring mutant forms of EGFR
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    The PP2A-Integrator-CDK9 axis fine-tunes transcription and can be targeted therapeutically in cancer
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  72. cancerres.aacrjournals.org cancerres.aacrjournals.org
    Integrated Screens Identify CDK1 as a Therapeutic Target in Advanced Gastrointestinal Stromal Tumors
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    The selective lipoprotein-associated phospholipase A2 inhibitor darapladib triggers irreversible actions on glioma cell apoptosis and mitochondrial dysfunction
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    Pathologic HIF1α signaling drives adipose progenitor dysfunction in obesity
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    DNA Damage Promotes TMPRSS2-ERG Oncoprotein Destruction and Prostate Cancer Suppression via Signaling Converged by GSK3β and WEE1
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    Insulin- and Lipopolysaccharide-Mediated Signaling in Adipose Tissue Macrophages Regulates Postprandial Glycemia through Akt-mTOR Activation
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    HectD1 controls hematopoietic stem cell regeneration by coordinating ribosome assembly and protein synthesis
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    Small Extracellular Vesicle Regulation of Mitochondrial Dynamics Reprograms a Hypoxic Tumor Microenvironment
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    Caloric Restriction Promotes Immunometabolic Reprogramming Leading to Protection from Tuberculosis
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    MiR-690, an exosomal-derived miRNA from M2-polarized macrophages, improves insulin sensitivity in obese mice
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    Functional Genomics Identifies Metabolic Vulnerabilities in Pancreatic Cancer
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    Central Ceramide Signaling Mediates Obesity-Induced Precocious Puberty
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    Glutamine Metabolism Controls Stem Cell Fate Reversibility and Long-Term Maintenance in the Hair Follicle
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    Combined Omics Approaches Reveal the Roles of Non-canonical WNT7B Signaling and YY1 in the Proliferation of Human Pancreatic Progenitor Cells
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    Cancer cells escape autophagy inhibition via NRF2-induced macropinocytosis
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    Reduced Mitochondrial Apoptotic Priming Drives Resistance to BH3 Mimetics in Acute Myeloid Leukemia
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    Developmental partitioning of SYK and ZAP70 prevents autoimmunity and cancer
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    Gene editing and synthetically accessible inhibitors reveal role for TPC2 in HCC cell proliferation and tumor growth
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    Triggering Receptor Expressed on Myeloid Cells-2 (TREM2) Interacts With Colony-Stimulating Factor 1 Receptor (CSF1R) but Is Not Necessary for CSF1/CSF1R-Mediated Microglial Survival
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  91. Mar 2021
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    Hericium erinaceus mycelium and its small bioactive compounds promote oligodendrocyte maturation with an increase in myelin basic protein
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    Transcriptional programming drives Ibrutinib-resistance evolution in mantle cell lymphoma
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    CXCR4 signaling at the fetal-maternal interface may drive inflammation and syncytia formation during ovine pregnancy †
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    An Embryonic Diapause-like Adaptation with Suppressed Myc Activity Enables Tumor Treatment Persistence
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  97. Feb 2021
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    Alternative signaling pathways from IGF1 or Insulin to Akt activation and Foxo1 nuclear efflux in adult skeletal muscle fibers
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      phospho-AKT Ser473

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    Selective targeting of the androgen receptor-DNA binding domain by the novel antiandrogen SBF-1 and inhibition of the growth of prostate cancer cells
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  100. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    PD-L1 Reverse Signaling in Dermal Dendritic Cells Promotes Dendritic Cell Migration Required for Skin Immunity
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  101. physoc.onlinelibrary.wiley.com physoc.onlinelibrary.wiley.com
    The insulin‐sensitizing effect of a single exercise bout is similar in type I and type II human muscle fibres
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  102. journals.sagepub.com journals.sagepub.com
    ErbB3 is a critical regulator of cytoskeletal dynamics in brain microvascular endothelial cells: Implications for vascular remodeling and blood-brain-barrier modulation - Limin Wu, Mohammad R Islam, Janice Lee, Hajime Takase, Shuzhen Guo, Allison M Andrews, Tetyana P Buzhdygan, Justin Mathew, Wenlu Li, Ken Arai, Eng H Lo, Servio H Ramirez, Josephine Lok, 2021
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  103. www.cell.com www.cell.com
    Mitochondrial Threonyl-tRNA Synthetase TARS2 Is Required for Threonine-Sensitive mTORC1 Activation
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    Inflammation-driven senescence-associated secretory phenotype in cancer-associated fibroblasts enhances peritoneal dissemination
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  105. onlinelibrary.wiley.com onlinelibrary.wiley.com
    LncRNA RP6‐65G23.1 accelerates proliferation and inhibits apoptosis via p‐ERK1/2/p‐AKT signaling pathway on keratinocytes
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  106. physoc.onlinelibrary.wiley.com physoc.onlinelibrary.wiley.com
    Reduced Na+K+‐ATPase activity may reduce amino acid uptake in IUGR fetal sheep muscle despite unchanged ex vivo amino acid transporter activity
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    Synergistic growth inhibition mediated by dual PI3K/mTOR pathway targeting and genetic or direct pharmacological AKT inhibition in human glioblastoma models
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    onlinelibrary.wiley.com/doi/10.1111/jnc.14899
  108. physoc.onlinelibrary.wiley.com physoc.onlinelibrary.wiley.com
    Insulin‐stimulated glucose uptake partly relies on p21‐activated kinase 2 (PAK2), but not PAK1, in mouse skeletal muscle
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      AB_329

      DOI: 10.1113/JP280294

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  109. www.sciencedirect.com www.sciencedirect.com
    An acetyl-histone vulnerability in PI3K/AKT inhibition-resistant cancers is targetable by both BET and HDAC inhibitors
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    sciencedirect.com/science/article/pii/S2211124721000577
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    ARHGEF3 regulates skeletal muscle regeneration and strength through autophagy
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      pSer473-Akt

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    sciencedirect.com/science/article/pii/S2211124721000449
  111. Jan 2021
  112. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A feed-forward regulatory loop in adipose tissue promotes signaling by the hepatokine FGF21
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  113. www.sciencedirect.com www.sciencedirect.com
    ARHGEF3 Regulates Skeletal Muscle Regeneration and Strength through Autophagy
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  114. Dec 2020
  115. physoc.onlinelibrary.wiley.com physoc.onlinelibrary.wiley.com
    Autoimmune activation of the GnRH receptor induces insulin resistance independent of obesity in a female rat model
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      RRID:AB_329825

      DOI: 10.14814/phy2.14672

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  116. faseb.onlinelibrary.wiley.com faseb.onlinelibrary.wiley.com
    Staphylococcus aureus Panton‐Valentine Leukocidin triggers an alternative NETosis process targeting mitochondria
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      DOI: 10.1096/fj.201902981R

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  117. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    Hetero-oligomerization of Rho and Ras GTPases Connects GPCR Activation to mTORC2-AKT Signaling
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      DOI: 10.1016/j.celrep.2020.108427

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  118. Nov 2020
  119. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    TSPAN1: A Novel Protein Involved in Head and Neck Squamous Cell Carcinoma Chemoresistance
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      pAKT

      DOI: 10.3390/cancers12113269

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  120. Oct 2020
  121. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    Enhancer Reprogramming Confers Dependence on Glycolysis and IGF Signaling in KMT2D Mutant Melanoma
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  122. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    A Small-Molecule Approach to Restore a Slow-Oxidative Phenotype and Defective CaMKIIβ Signaling in Limb Girdle Muscular Dystrophy
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  123. www.jneurosci.org www.jneurosci.org
    Phosphorylation of eIF2α promotes Schwann cell differentiation and myelination in CMT1B mice with activated UPR
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  124. academic.oup.com academic.oup.com
    Mechanisms by which membrane and nuclear ER alpha inhibit adipogenesis in cells isolated from female mice
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      DOI: 10.1210/endocr/bqaa175

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  125. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    TGFβR-SMAD3 Signaling Induces Resistance to PARP Inhibitors in the Bone Marrow Microenvironment
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  126. www.sciencedirect.com www.sciencedirect.com
    MED19 Regulates Adipogenesis and Maintenance of White Adipose Tissue Mass by Mediating PPARγ-Dependent Gene Expression
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  127. Sep 2020
  128. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    Maternal exercise attenuates the lower skeletal muscle glucose uptake and insulin secretion caused by paternal obesity in female adult rat offspring
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  129. www.sciencedirect.com www.sciencedirect.com
    Metabolic Imaging Detects Resistance to PI3Kα Inhibition Mediated by Persistent FOXM1 Expression in ER+ Breast Cancer
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  130. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    HSP90 Inhibitor, 17-DMAG, Alone and in Combination with Lapatinib Attenuates Acquired Lapatinib-Resistance in ER-positive, HER2-Overexpressing Breast Cancer Cell Line
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      DOI: 10.3390/cancers12092630

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  131. diabetes.diabetesjournals.org diabetes.diabetesjournals.org
    A Single Bout of One-legged Exercise to Local Exhaustion Decreases Insulin Action in Non-exercised Muscle Leading to Decreased Whole-body Insulin Action
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  132. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Enhanced Akt/GSK‐3β/CREB signaling mediates the anti‐inflammatory actions of mGluR5 positive allosteric modulators in microglia and following traumatic brain injury in male mice
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  133. www.sciencedirect.com www.sciencedirect.com
    Enhancer-Driven lncRNA BDNF-AS Induces Endocrine Resistance and Malignant Progression of Breast Cancer through the RNH1/TRIM21/mTOR Cascade
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    Metabolic Control over mTOR-Dependent Diapause-like State
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  135. link.springer.com link.springer.com
    Pharmacological targeting of α3β4 nicotinic receptors improves peripheral insulin sensitivity in mice with diet-induced obesity
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    Nutrient-Driven O-GlcNAcylation Controls DNA Damage Repair Signaling and Stem/Progenitor Cell Homeostasis
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    Dissociation of Adaptive Thermogenesis from Glucose Homeostasis in Microbiome-Deficient Mice
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  138. onlinelibrary.wiley.com onlinelibrary.wiley.com
    High‐frequency transcranial magnetic stimulation protects APP/PS1 mice against Alzheimer’s disease progress by reducing APOE and enhancing autophagy
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    Streptococcus pneumoniae Infection Promotes Histone H3 Dephosphorylation by Modulating Host PP1 Phosphatase
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    Formation of Human Neuroblastoma in Mouse-Human Neural Crest Chimeras
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  141. academic.oup.com academic.oup.com
    The endothelial barrier is not rate-limiting to insulin action in the myocardium of male mice
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      DOI: 10.1210/endocr/bqaa029

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  142. www.sciencedirect.com www.sciencedirect.com
    Molecular Stressors Engender Protein Connectivity Dysfunction through Aberrant N-Glycosylation of a Chaperone
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      DOI: 10.1016/j.celrep.2020.107840

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  143. elifesciences.org elifesciences.org
    Analysis of pulsed cisplatin signalling dynamics identifies effectors of resistance in lung adenocarcinoma
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  144. www.sciencedirect.com www.sciencedirect.com
    Low-Dose Vertical Inhibition of the RAF-MEK-ERK Cascade Causes Apoptotic Death of KRAS Mutant Cancers
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      RRID:AB_329825

      DOI: 10.1016/j.celrep.2020.107764

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  145. www.jneurosci.org www.jneurosci.org
    Differential Signaling Mediated by ApoE2, ApoE3, and ApoE4 in Human Neurons Parallels Alzheimer's Disease Risk
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      DOI: 10.1523/JNEUROSCI.2994-18.2019

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  146. www.sciencedirect.com www.sciencedirect.com
    Topological Adaptation of Transmembrane Domains to the Force-Modulated Lipid Bilayer Is a Basis of Sensing Mechanical Force
    1
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      DOI: 10.1016/j.cub.2020.02.028

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  147. www.sciencedirect.com www.sciencedirect.com
    Cancer causes metabolic perturbations associated with reduced insulin-stimulated glucose uptake in peripheral tissues and impaired muscle microvascular perfusion
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      DOI: 10.1016/j.metabol.2020.154169

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  148. www.cell.com www.cell.com
    Late Endosomes Act as mRNA Translation Platforms and Sustain Mitochondria in Axons
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      DOI: 10.1016/j.cell.2018.11.030

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    cell.com/cell/abstract/S0092-8674(18)31555-1
  149. link.springer.com link.springer.com
    Effects of acute aerobic, resistance and combined exercises on 24-h glucose variability and skeletal muscle signalling responses in type 1 diabetics
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      RRID:AB_329825

      DOI: 10.1007/s00421-020-04491-6

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  150. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    Synthesis, biological evaluation and toxicity of novel tetrandrine analogues
    1
    1. scibot 09 Sep 2020
      phospho-Akt

      DOI: 10.1016/j.ejmech.2020.112810

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  151. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Acute pharmacological inhibition of matrix metalloproteinase‐9 activity during development restores perineuronal net formation and normalizes auditory processing in Fmr1 KO mice
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      RRID:AB_329825

      DOI: 10.1111/jnc.15037

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  152. academic.oup.com academic.oup.com
    DPP-4 inhibition with anagliptin reduces lipotoxicity-induced insulin resistance and steatohepatitis in male mice
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      DOI: 10.1210/endocr/bqaa139

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  153. www.sciencedirect.com www.sciencedirect.com
    Tau Reduction Prevents Key Features of Autism in Mouse Models
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      DOI: 10.1016/j.neuron.2020.01.038

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  154. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Translational Physiology: Insulin signaling displayed a differential tissue-specific response to low-dose dihydrotestosterone in female mice
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      DOI: 10.1152/ajpendo.00195.2017

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  155. www.sciencedirect.com www.sciencedirect.com
    Evidence That STK19 Is Not an NRAS-dependent Melanoma Driver
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      DOI: 10.1016/j.cell.2020.04.014

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    Protein synthesis inhibition promotes nitric oxide generation and activation of CGKII-dependent downstream signaling pathways in the retina
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      DOI: 10.1016/j.bbamcr.2020.118732

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  157. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Three-dimensional growth of breast cancer cells potentiates the anti-tumor effects of unacylated ghrelin and AZP-531
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      DOI: 10.7554/eLife.56913

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  158. www.sciencedirect.com www.sciencedirect.com
    Hyperactivation of TORC1 Drives Resistance to the Pan-HER Tyrosine Kinase Inhibitor Neratinib in HER2-Mutant Cancers
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      DOI: 10.1016/j.ccell.2019.12.013

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    Developmental and Tumor Angiogenesis Requires the Mitochondria-Shaping Protein Opa1
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      Rabbit anti-Phospho-Akt (Ser473) Antibody

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  160. www.jci.org www.jci.org
    Microphthalmia transcription factor expression contributes to bone marrow failure in Fanconi anemia
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      rabbit anti–phospho-AKT(Ser473)

      DOI: 10.1172/JCI131540

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  161. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    BPS Publications
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      DOI: 10.1111/bph.14918

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  162. faseb.onlinelibrary.wiley.com faseb.onlinelibrary.wiley.com
    β2‐adrenoceptor activation improves skeletal muscle autophagy in neurogenic myopathy
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      DOI: 10.1096/fj.201902305R

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  163. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    AMPK-Regulated Astrocytic Lactate Shuttle Plays a Non-Cell-Autonomous Role in Neuronal Survival
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      Phospho-Akt (Ser473)

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  164. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Diet Intake Control Is Indispensable for the Gluconeogenic Response to Sodium‐Glucose Cotransporter 2 Inhibition in Male Mice
    1
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      anti‐phospho‐Akt

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  165. academic.oup.com academic.oup.com
    Estrogen Stimulation of Pleiotrophin Enhances Osteoblast Differentiation and Maintains Bone Mass in IGFBP-2 Null Mice
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      RRID:AB_329825

      DOI: 10.1210/endocr/bqz007

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  166. Aug 2020
  167. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Cathepsin B inhibition blocks neurite outgrowth in cultured neurons by regulating lysosomal trafficking and remodeling
    1
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      RRID:AB_329826

      DOI: 10.1111/jnc.15032

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  168. Jan 2020
  169. elifesciences.org elifesciences.org
    Obesity-linked suppression of membrane-bound O-acyltransferase 7 (MBOAT7) drives non-alcoholic fatty liver disease
    1
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      RRID:AB_329825

      DOI: 10.7554/eLife.49882

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  170. www.sciencedirect.com www.sciencedirect.com
    Enhanced mGlu5 Signaling in Excitatory Neurons Promotes Rapid Antidepressant Effects via AMPA Receptor Activation
    1
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    Divergent Polypharmacology-Driven Cellular Activity of Structurally Similar Multi-Kinase Inhibitors through Cumulative Effects on Individual Targets
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    A novel 2‐aminobenzimidazole‐based compound Jzu 17 exhibits anti‐ angiogenesis effects via targeting VEGFR‐2 signaling
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    Acyl-CoA-Binding Protein Is a Lipogenic Factor that Triggers Food Intake and Obesity
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    Combination of Hypoglycemia and Metformin Impairs Tumor Metabolic Plasticity and Growth by Modulating the PP2A-GSK3β-MCL-1 Axis
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    High-endothelial cell-derived S1P regulates dendritic cell localization and vascular integrity in the lymph node
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    PAK4 Kinase Activity Plays a Crucial Role in the Podosome Ring of Myeloid Cells
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    Molecularly Distinct Clathrin-Coated Pits Differentially Impact EGFR Fate and Signaling
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    DIRAS3 (ARHI) Blocks RAS/MAPK Signaling by Binding Directly to RAS and Disrupting RAS Clusters
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    Deletion of Fmr1 from Forebrain Excitatory Neurons Triggers Abnormal Cellular, EEG, and Behavioral Phenotypes in the Auditory Cortex of a Mouse Model of Fragile X Syndrome
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    Gestational intermittent hypoxia induces endothelial dysfunction, reduces perivascular adiponectin and causes epigenetic changes in adult male offspring
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    Myc‐dependent endothelial proliferation is controlled by phosphotyrosine 1212 in VEGF receptor‐2
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    CRH Promotes the Neurogenic Activity of Neural Stem Cells in the Adult Hippocampus
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    Hepatic nitric oxide synthase 1 adaptor protein regulates glucose homeostasis and hepatic insulin sensitivity in obese mice depending on its PDZ binding domain
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    GPD1 Specifically Marks Dormant Glioma Stem Cells with a Distinct Metabolic Profile
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    α-Ketoglutarate-Activated NF-κB Signaling Promotes Compensatory Glucose Uptake and Brain Tumor Development
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    Small-Molecule and CRISPR Screening Converge to Reveal Receptor Tyrosine Kinase Dependencies in Pediatric Rhabdoid Tumors
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    Paradigms for Precision Medicine in Epichaperome Cancer Therapy
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    Lipid Deprivation Induces a Stable, Naive-to-Primed Intermediate State of Pluripotency in Human PSCs
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    Endogenous IGF Signaling Directs Heterogeneous Mesoderm Differentiation in Human Embryonic Stem Cells
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    A Breakdown in Metabolic Reprogramming Causes Microglia Dysfunction in Alzheimer's Disease
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    mTORC1 Activation Requires DRAM-1 by Facilitating Lysosomal Amino Acid Efflux
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    Role of hepatic glucocorticoid receptor in metabolism in models of 5αR1 Deficiency in Male Mice
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    WNT-Mediated Regulation of FOXO1 Constitutes a Critical Axis Maintaining Pubertal Mammary Stem Cell Homeostasis
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    Functional Redundancy between β1 and β3 Integrin in Activating the IR/Akt/mTORC1 Signaling Axis to Promote ErbB2-Driven Breast Cancer
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    Hepatic gluconeogenic response to single and long-term SGLT2 inhibition in lean/obese male hepatic G6pc-reporter mice
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    A novel small molecule supports the survival of cultured dopamine neurons and may restore the dopaminergic innervation of the brain in the MPTP mouse model of Parkinson's disease
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    3D Cellular Architecture Modulates Tyrosine Kinase Activity, Thereby Switching CD95-Mediated Apoptosis to Survival
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    Impaired skeletal muscle mitochondrial pyruvate uptake rewires glucose metabolism to drive whole-body leanness
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    Astrocyte truncated tropomyosin receptor kinase B mediates brain‐derived neurotrophic factor anti‐apoptotic effect leading to neuroprotection
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    IGF-2 Preprograms Maturing Macrophages to Acquire Oxidative Phosphorylation-Dependent Anti-inflammatory Properties
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    Auto-regulation of Secretory Flux by Sensing and Responding to the Folded Cargo Protein Load in the Endoplasmic Reticulum
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    Reciprocal Effects of Fibroblast Growth Factor Receptor Signaling on Dengue Virus Replication and Virion Production
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    1. scibot 13 Jan 2020
      RRID:AB_329825

      DOI: 10.1016/j.celrep.2019.04.105

      Resource: (Cell Signaling Technology Cat# 9271, RRID:AB_329825)

      Curator: @ethanbadger

      SciCrunch record: RRID:AB_329825

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      RRID:AB_329825 RRIDCUR:Validated
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    sciencedirect.com/science/article/pii/S2211124719305856
  210. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    Haem oxygenase‐1 up‐regulation by rosiglitazone via ROS‐dependent Nrf2‐antioxidant response elements axis or PPARγ attenuates LPS‐mediated lung inflammation
    1
    1. scibot 13 Jan 2020
      RRID:AB_329825

      DOI: 10.1111/bph.14465

      Resource: (Cell Signaling Technology Cat# 9271, RRID:AB_329825)

      Curator: @Jmenke

      SciCrunch record: RRID:AB_329825

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      RRID:AB_329825 RRIDCUR:Validated
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    bpspubs.onlinelibrary.wiley.com/doi/full/10.1111/bph.14465
  211. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    Betulinic acid alleviates endoplasmic reticulum stress‐mediated nonalcoholic fatty liver disease through activation of farnesoid X receptors in mice
    1
    1. scibot 13 Jan 2020
      RRID:AB_329825

      DOI: 10.1111/bph.14570

      Resource: (Cell Signaling Technology Cat# 9271, RRID:AB_329825)

      Curator: @Naa003

      SciCrunch record: RRID:AB_329825

      What is this?

      RRID:AB_329825 RRIDCUR:Validated
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    bpspubs.onlinelibrary.wiley.com/doi/full/10.1111/bph.14570