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69 Matching Annotations

Mar 2026
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Lack of GPNMB Is Associated With Altered Lipid and Glucose Metabolism and Disrupted Diurnal Hepatic Glycogen Regulation

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1. scibot 11 Mar 2026
  
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  DOI: 10.1096/fj.202504363R
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12969540/
54.241.53.176 54.241.53.176

1-s2.0-S2589004226006000-main-html.html

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1. scibot 05 Mar 2026
  
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  DOI: 10.1016/j.isci.2026.115225
  
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54.241.53.176/a221b687932a8fac5c0494841179a4e1147d7aa5/1-s2.0-S2589004226006000-main-html.html
Feb 2026
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Deletion of Mfn2 in endothelial cells triggers a mitohormetic response that improves systemic metabolism and healthspan in mice

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1. scibot 19 Feb 2026
  
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  DOI: 10.1016/j.cmet.2026.01.012
  
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sciencedirect.com/science/article/pii/S1550413126000124
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Ablation of Tumor-Derived IGFBP-3 Attenuates Cancer-Associated Skeletal Muscle Wasting in Murine Pancreatic Cancer

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1. scibot 14 Feb 2026
  
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  DOI: 10.1152/ajpcell.00421.2025
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12893420/
Jan 2026
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Using an Unbiased Coexpression Network to Reveal Cross‐Talking Pathways of Phosphoinositide‐3‐Kinase Regulatory Subunit 1 in Skin Aging and Rejuvenation

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1. scibot 22 Jan 2026
  
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  DOI: 10.1096/fj.202402347RRRR
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12811739/
54.241.53.176 54.241.53.176

sechrist-et-al-2026-ablation-of-tumor-derived-igfbp-3-attenuates-cancer-associated-skeletal-muscle-wasting-in-murine-html.html

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1. scibot 16 Jan 2026
  
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  DOI: 10.6084/m9.figshare.30888119
  
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54.241.53.176/7fd943f535bcae714c35afd57a159fa840c2e99c/sechrist-et-al-2026-ablation-of-tumor-derived-igfbp-3-attenuates-cancer-associated-skeletal-muscle-wasting-in-murine-html.html
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Endometrial stromal cell-derived TMAO sustains decidualization to prevent recurrent spontaneous abortion

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1. scibot 09 Jan 2026
  
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  DOI: 10.1016/j.cmet.2025.11.014
  
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sciencedirect.com/science/article/pii/S1550413125005285
Nov 2025
www.sciencedirect.com:5037 www.sciencedirect.com:5037

Potentiation of noncanonical NF-κB signaling and marginal zone B cell expansion by CARD11-mediated regulation of p100 processing

1
1. scibot 29 Nov 2025
  
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  DOI: 10.1016/j.celrep.2025.116616
  
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sciencedirect.com:5037/science/article/pii/S2211124725013889
Oct 2025
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Reversal of diet-induced obesity by central insulin sensitizer FSTL1

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1. scibot 22 Oct 2025
  
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  DOI: 10.1016/j.neuron.2025.09.036
  
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sciencedirect.com/science/article/pii/S0896627325007494
Jul 2025
alz-journals.onlinelibrary.wiley.com alz-journals.onlinelibrary.wiley.com

Interconnections of insulin/IGF-1 signaling and autophagy abnormalities in Alzheimer's disease

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1. scibot 08 Jul 2025
  
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  DOI: 10.1002/alz.70099
  
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alz-journals.onlinelibrary.wiley.com/doi/10.1002/alz.70099
Mar 2025
52.53.155.43 52.53.155.43

1-s2.0-S2589004225004043-main-html.html

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1. scibot 06 Mar 2025
  
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  DOI: 10.1016/j.isci.2025.112144
  
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52.53.155.43/a54d23b2534862197be3e5d5ad98a8cc187610fd/1-s2.0-S2589004225004043-main-html.html
Feb 2025
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A microRNA-regulated transcriptional state defines intratumoral CD8+ T cells that respond to immunotherapy

1
1. scibot 14 Feb 2025
  
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  DOI: 10.1016/j.celrep.2025.115301
  
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sciencedirect.com/science/article/pii/S2211124725000725
Aug 2024
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CD38-NAD+Axis Regulates Immunotherapeutic Anti-Tumor T Cell Response

1
1. scibot 21 Aug 2024
  
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  DOI: 10.1016/j.cmet.2017.10.006
  
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sciencedirect.com/science/article/pii/S1550413117306186
Apr 2024
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Thbs1 regulates skeletal muscle mass in a TGFβ-Smad2/3-ATF4-dependent manner

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1. scibot 30 Apr 2024
  
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  DOI: 10.1016/j.celrep.2024.114149
  
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sciencedirect.com/science/article/pii/S2211124724004777
Mar 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Effects of hindlimb unloading on the mevalonate and mechanistic target of rapamycin complex 1 signaling pathways in a fast‐twitch muscle in rats

1
1. scibot 09 Mar 2024
  
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  DOI: 10.14814/phy2.15969
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10920058/
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FOXO1 stimulates tip cell-enriched gene expression in endothelial cells

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1. scibot 07 Mar 2024
  
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  DOI: 10.1016/j.isci.2024.109161
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10914484/
Feb 2024
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Trans-omic analysis reveals opposite metabolic dysregulation between feeding and fasting in liver associated with obesity

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1. scibot 27 Feb 2024
  
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  Cell Signaling Technology#9461
  
  DOI: 10.1016/j.isci.2024.109121
  
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sciencedirect.com/science/article/pii/S2589004224003420
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Stromal-derived MAOB promotes prostate cancer growth and progression

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1. scibot 14 Feb 2024
  
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  DOI: 10.1126/sciadv.adi4935
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10857382/
Oct 2023
aacrjournals.org aacrjournals.org

Piperacetazine directly binds to the PAX3::FOXO1 fusion protein and inhibits its transcriptional activity.

1
1. scibot 07 Oct 2023
  
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  RRID:AB_329831
  
  DOI: 10.1158/2767-9764.CRC-23-0119
  
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aacrjournals.org/cancerrescommun/article/3/10/2030/729478/Piperacetazine-Directly-Binds-to-the-PAX3-FOXO1
Sep 2023
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PARP1 inhibition protects mice against Japanese encephalitis virus infection

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1. scibot 08 Sep 2023
  
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  DOI: 10.1016/j.celrep.2023.113103
  
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sciencedirect.com/science/article/pii/S2211124723011142
Aug 2023
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Autophagy ablation in skeletal muscles worsens sepsis-induced muscle wasting, impairs whole-body metabolism, and decreases survival.

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1. scibot 19 Aug 2023
  
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  DOI: 10.1016/j.isci.2023.107475
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10425945/
Jul 2023
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GSDMA3 deficiency reprograms cellular metabolism and modulates BCR signaling in murine B cells

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1. scibot 21 Jul 2023
  
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  DOI: 10.1016/j.isci.2023.107341
  
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sciencedirect.com/science/article/pii/S2589004223014189
Jun 2023
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Identification of XAF1 as an endogenous AKT inhibitor

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1. scibot 29 Jun 2023
  
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  RRID:AB_329831
  
  DOI: 10.1016/j.celrep.2023.112690
  
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sciencedirect.com/science/article/pii/S2211124723007015
Apr 2023
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CD36 regulates diurnal glucose metabolism and hepatic clock to maintain glucose homeostasis in mice

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1. scibot 23 Apr 2023
  
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  DOI: 10.1016/j.isci.2023.106524
  
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sciencedirect.com/science/article/pii/S2589004223006016
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Accumulation of branched-chain amino acids reprograms glucose metabolism in CD8+ T cells with enhanced effector function and anti-tumor response

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1. scibot 20 Apr 2023
  
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  DOI: 10.1016/j.celrep.2023.112186
  
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sciencedirect.com/science/article/pii/S2211124723001973
Mar 2023
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Metformin Prevents Endothelial Oxidative Stress and Microvascular Insulin Resistance during Obesity Development in Male Rats

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1. scibot 05 Mar 2023
  
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  DOI: 10.1152/ajpendo.00240.2021
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8897003/
Feb 2023
52.53.155.43 52.53.155.43

Glucagon receptor blockage inhibits β-cell dedifferentiation through FoxO1

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1. scibot 03 Feb 2023
  
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  DOI: 10.1152/ajpendo.00101.2022
  
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52.53.155.43/97cababe8444826962bdfef0d07cded9be0e854b/ajpendo.00101.2022-html.html
Oct 2022
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Vps37a regulates hepatic glucose production by controlling glucagon receptor localization to endosomes

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1. scibot 18 Oct 2022
  
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  DOI: 10.1016/j.cmet.2022.09.022
  
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sciencedirect.com/science/article/pii/S1550413122004120
Jul 2022
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Slc12a8 in the lateral hypothalamus maintains energy metabolism and skeletal muscle functions during aging

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1. scibot 30 Jul 2022
  
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  DOI: 10.1016/j.celrep.2022.111131
  
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sciencedirect.com/science/article/pii/S2211124722009378
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Upregulation of FOXO1 contributes to lipopolysaccharide-induced pulmonary endothelial injury by induction of autophagy

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1. scibot 12 Jul 2022
  
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  RRID:AB_329831
  
  DOI: 10.21037/atm-21-5380
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9263762/
Jan 2022
link.springer.com link.springer.com

Involvement of FoxO1, Sp1, and Nrf2 in Upregulation of Negative Regulator of ROS by 15d-PGJ2 Attenuates H2O2-Induced IL-6 Expression in Rat Brain Astrocytes

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1. scibot 11 Jan 2022
  
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  DOI: 10.1007/s12640-020-00318-6
  
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link.springer.com/article/10.1007/s12640-020-00318-6
Dec 2021
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Engineering immunoproteasome-expressing mesenchymal stromal cells: A potent cellular vaccine for lymphoma and melanoma in mice

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1. scibot 28 Dec 2021
  
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  DOI: 10.1016/j.xcrm.2021.100455
  
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sciencedirect.com/science/article/pii/S2666379121003232
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TOX4, an insulin receptor-independent regulator of hepatic glucose production, is activated in diabetic liver

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1. scibot 16 Dec 2021
  
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  DOI: 10.1016/j.cmet.2021.11.013
  
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sciencedirect.com/science/article/pii/S1550413121005416
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The role of epithelial progesterone receptor isoforms in embryo implantation

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1. scibot 08 Dec 2021
  
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  DOI: 10.1016/j.isci.2021.103487
  
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sciencedirect.com/science/article/pii/S2589004221014589
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FOXO1 represses lymphatic valve formation and maintenance via PRDM1

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ADH5-mediated NO bioactivity maintains metabolic homeostasis in brown adipose tissue

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RNF8-mediated regulation of Akt promotes lung cancer cell survival and resistance to DNA damage

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PI3Kδ coordinates transcriptional, chromatin, and metabolic changes to promote effector CD8+ T cells at the expense of central memory

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Akt regulates Sox10 expression to control oligodendrocyte differentiation via phosphorylating FoxO1

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Delivery of membrane impermeable molecules to primary mouse T lymphocytes

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Isthmin-1 is an adipokine that promotes glucose uptake and improves glucose tolerance and hepatic steatosis

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Glycolytic ATP fuels phosphoinositide 3-kinase signaling to support effector T helper 17 cell responses

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Anti-inflammatory Roles of Glucocorticoids Are Mediated by Foxp3+ Regulatory T Cells via a miR-342-Dependent Mechanism

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Developmental partitioning of SYK and ZAP70 prevents autoimmunity and cancer

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Selective targeting of the androgen receptor-DNA binding domain by the novel antiandrogen SBF-1 and inhibition of the growth of prostate cancer cells

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Opposing p53 and mTOR/AKT promote an in vivo switch from apoptosis to senescence upon telomere shortening in zebrafish

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Low-Dose Vertical Inhibition of the RAF-MEK-ERK Cascade Causes Apoptotic Death of KRAS Mutant Cancers

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FoxO3a requires BAF57, a subunit of chromatin remodeler SWI/SNF complex for induction of PUMA in a model of Parkinson’s disease

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Angiotensin II-upregulated MAP kinase phosphatase-3 modulates FOXO1 and p21 in adrenocortical H295R cells

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Non-canonical mTORC2 Signaling Regulates Brown Adipocyte Lipid Catabolism through SIRT6-FoxO1

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Individual Cells Can Resolve Variations in Stimulus Intensity along the IGF-PI3K-AKT Signaling Axis

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Acylglycerol Kinase Maintains Metabolic State and Immune Responses of CD8+ T Cells

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Pro-Survival Lipid Sphingosine-1-Phosphate Metabolically Programs T Cells to Limit Anti-tumor Activity

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WNT-Mediated Regulation of FOXO1 Constitutes a Critical Axis Maintaining Pubertal Mammary Stem Cell Homeostasis

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In Vivo Decoding Mechanisms of the Temporal Patterns of Blood Insulin by the Insulin-AKT Pathway in the Liver

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Super-Obese Patient-Derived iPSC Hypothalamic Neurons Exhibit Obesogenic Signatures and Hormone Responses

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CD38-NAD+Axis Regulates Immunotherapeutic Anti-Tumor T Cell Response

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Timed Inhibition of Orexin System by Suvorexant Improved Sleep and Glucose Metabolism in Type 2 Diabetic db/db Mice

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FoxO1 Promotes Mitophagy in the Podocytes of Diabetic Male Mice via the PINK1/Parkin Pathway

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Glucose Sensing by Skeletal Myocytes Couples Nutrient Signaling to Systemic Homeostasis

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Low-Dose Dihydrotestosterone Drives Metabolic Dysfunction via Cytosolic and Nuclear Hepatic Androgen Receptor Mechanisms

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Hippo Signaling Suppresses Cell Ploidy and Tumorigenesis through Skp2

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