57 Matching Annotations
  1. Aug 2024
  2. www.sciencedirect.com www.sciencedirect.com
    CD38-NAD+Axis Regulates Immunotherapeutic Anti-Tumor T Cell Response
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    1. scibot 21 Aug 2024
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    sciencedirect.com/science/article/pii/S1550413117306186
  3. Apr 2024
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    Thbs1 regulates skeletal muscle mass in a TGFβ-Smad2/3-ATF4-dependent manner
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    1. scibot 30 Apr 2024
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      DOI: 10.1016/j.celrep.2024.114149

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    sciencedirect.com/science/article/pii/S2211124724004777
  5. Mar 2024
  6. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Effects of hindlimb unloading on the mevalonate and mechanistic target of rapamycin complex 1 signaling pathways in a fast‐twitch muscle in rats
    1
    1. scibot 09 Mar 2024
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    ncbi.nlm.nih.gov/pmc/articles/PMC10920058/
  7. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    FOXO1 stimulates tip cell-enriched gene expression in endothelial cells
    1
    1. scibot 07 Mar 2024
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    ncbi.nlm.nih.gov/pmc/articles/PMC10914484/
  8. Feb 2024
  9. www.sciencedirect.com www.sciencedirect.com
    Trans-omic analysis reveals opposite metabolic dysregulation between feeding and fasting in liver associated with obesity
    1
    1. scibot 27 Feb 2024
      Cell Signaling Technology#9461

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    sciencedirect.com/science/article/pii/S2589004224003420
  10. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Stromal-derived MAOB promotes prostate cancer growth and progression
    1
    1. scibot 14 Feb 2024
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      DOI: 10.1126/sciadv.adi4935

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    ncbi.nlm.nih.gov/pmc/articles/PMC10857382/
  11. Oct 2023
  12. aacrjournals.org aacrjournals.org
    Piperacetazine directly binds to the PAX3::FOXO1 fusion protein and inhibits its transcriptional activity.
    1
    1. scibot 07 Oct 2023
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      DOI: 10.1158/2767-9764.CRC-23-0119

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    aacrjournals.org/cancerrescommun/article/3/10/2030/729478/Piperacetazine-Directly-Binds-to-the-PAX3-FOXO1
  13. Sep 2023
  14. www.sciencedirect.com www.sciencedirect.com
    PARP1 inhibition protects mice against Japanese encephalitis virus infection
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    1. scibot 08 Sep 2023
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    sciencedirect.com/science/article/pii/S2211124723011142
  15. Aug 2023
  16. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Autophagy ablation in skeletal muscles worsens sepsis-induced muscle wasting, impairs whole-body metabolism, and decreases survival.
    1
    1. scibot 19 Aug 2023
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    ncbi.nlm.nih.gov/pmc/articles/PMC10425945/
  17. Jul 2023
  18. www.sciencedirect.com www.sciencedirect.com
    GSDMA3 deficiency reprograms cellular metabolism and modulates BCR signaling in murine B cells
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    1. scibot 21 Jul 2023
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      DOI: 10.1016/j.isci.2023.107341

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    sciencedirect.com/science/article/pii/S2589004223014189
  19. Jun 2023
  20. www.sciencedirect.com www.sciencedirect.com
    Identification of XAF1 as an endogenous AKT inhibitor
    1
    1. scibot 29 Jun 2023
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    sciencedirect.com/science/article/pii/S2211124723007015
  21. Apr 2023
  22. www.sciencedirect.com www.sciencedirect.com
    CD36 regulates diurnal glucose metabolism and hepatic clock to maintain glucose homeostasis in mice
    1
    1. scibot 23 Apr 2023
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    sciencedirect.com/science/article/pii/S2589004223006016
  23. www.sciencedirect.com www.sciencedirect.com
    Accumulation of branched-chain amino acids reprograms glucose metabolism in CD8+ T cells with enhanced effector function and anti-tumor response
    1
    1. scibot 20 Apr 2023
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      DOI: 10.1016/j.celrep.2023.112186

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    sciencedirect.com/science/article/pii/S2211124723001973
  24. Mar 2023
  25. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Metformin Prevents Endothelial Oxidative Stress and Microvascular Insulin Resistance during Obesity Development in Male Rats
    1
    1. scibot 05 Mar 2023
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      DOI: 10.1152/ajpendo.00240.2021

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    ncbi.nlm.nih.gov/pmc/articles/PMC8897003/
  26. Feb 2023
  27. 52.53.155.43 52.53.155.43
    Glucagon receptor blockage inhibits β-cell dedifferentiation through FoxO1
    1
    1. scibot 03 Feb 2023
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      DOI: 10.1152/ajpendo.00101.2022

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    52.53.155.43/97cababe8444826962bdfef0d07cded9be0e854b/ajpendo.00101.2022-html.html
  28. Oct 2022
  29. www.sciencedirect.com www.sciencedirect.com
    Vps37a regulates hepatic glucose production by controlling glucagon receptor localization to endosomes
    1
    1. scibot 18 Oct 2022
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      DOI: 10.1016/j.cmet.2022.09.022

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    sciencedirect.com/science/article/pii/S1550413122004120
  30. Jul 2022
  31. www.sciencedirect.com www.sciencedirect.com
    Slc12a8 in the lateral hypothalamus maintains energy metabolism and skeletal muscle functions during aging
    1
    1. scibot 30 Jul 2022
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      DOI: 10.1016/j.celrep.2022.111131

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    sciencedirect.com/science/article/pii/S2211124722009378
  32. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Upregulation of FOXO1 contributes to lipopolysaccharide-induced pulmonary endothelial injury by induction of autophagy
    1
    1. scibot 12 Jul 2022
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      DOI: 10.21037/atm-21-5380

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    ncbi.nlm.nih.gov/pmc/articles/PMC9263762/
  33. Jan 2022
  34. link.springer.com link.springer.com
    Involvement of FoxO1, Sp1, and Nrf2 in Upregulation of Negative Regulator of ROS by 15d-PGJ2 Attenuates H2O2-Induced IL-6 Expression in Rat Brain Astrocytes
    1
    1. scibot 11 Jan 2022
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      DOI: 10.1007/s12640-020-00318-6

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    link.springer.com/article/10.1007/s12640-020-00318-6
  35. Dec 2021
  36. www.sciencedirect.com www.sciencedirect.com
    Engineering immunoproteasome-expressing mesenchymal stromal cells: A potent cellular vaccine for lymphoma and melanoma in mice
    1
    1. scibot 28 Dec 2021
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      DOI: 10.1016/j.xcrm.2021.100455

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    sciencedirect.com/science/article/pii/S2666379121003232
  37. www.sciencedirect.com www.sciencedirect.com
    TOX4, an insulin receptor-independent regulator of hepatic glucose production, is activated in diabetic liver
    1
    1. scibot 16 Dec 2021
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      DOI: 10.1016/j.cmet.2021.11.013

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    sciencedirect.com/science/article/pii/S1550413121005416
  38. www.sciencedirect.com www.sciencedirect.com
    The role of epithelial progesterone receptor isoforms in embryo implantation
    1
    1. scibot 08 Dec 2021
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      DOI: 10.1016/j.isci.2021.103487

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    sciencedirect.com/science/article/pii/S2589004221014589
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    FOXO1 represses lymphatic valve formation and maintenance via PRDM1
    1
    1. scibot 01 Dec 2021
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      DOI: 10.1016/j.celrep.2021.110048

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    sciencedirect.com/science/article/pii/S2211124721015345
  40. Nov 2021
  41. www.sciencedirect.com www.sciencedirect.com
    ADH5-mediated NO bioactivity maintains metabolic homeostasis in brown adipose tissue
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    1. scibot 17 Nov 2021
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      DOI: 10.1016/j.celrep.2021.110003

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    sciencedirect.com/science/article/pii/S2211124721014819
  42. Oct 2021
  43. www.sciencedirect.com www.sciencedirect.com
    RNF8-mediated regulation of Akt promotes lung cancer cell survival and resistance to DNA damage
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    1. scibot 21 Oct 2021
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      DOI: 10.1016/j.celrep.2021.109854

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    sciencedirect.com/science/article/pii/S2211124721013218
  44. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    BPS Publications
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    1. scibot 20 Oct 2021
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      DOI: 10.1111/bph.15625

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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.15625
  45. www.sciencedirect.com www.sciencedirect.com
    PI3Kδ coordinates transcriptional, chromatin, and metabolic changes to promote effector CD8+ T cells at the expense of central memory
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    1. scibot 13 Oct 2021
      9461

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    sciencedirect.com/science/article/pii/S221112472101264X
  46. www.jneurosci.org www.jneurosci.org
    Akt regulates Sox10 expression to control oligodendrocyte differentiation via phosphorylating FoxO1
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    1. scibot 09 Oct 2021
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      DOI: 10.1523/JNEUROSCI.2432-20.2021

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    jneurosci.org/content/41/39/8163
  47. Aug 2021
  48. www.sciencedirect.com www.sciencedirect.com
    Delivery of membrane impermeable molecules to primary mouse T lymphocytes
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    1. scibot 18 Aug 2021
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      DOI: 10.1016/j.xpro.2021.100757

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    sciencedirect.com/science/article/pii/S2666166721004639
  49. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Untitled document
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    1. scibot 11 Aug 2021
      AB_329831

      DOI: 10.1210/en.2017-00677

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    ncbi.nlm.nih.gov/pmc/articles/PMC5761600/
  50. www.sciencedirect.com www.sciencedirect.com
    Isthmin-1 is an adipokine that promotes glucose uptake and improves glucose tolerance and hepatic steatosis
    1
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      DOI: 10.1016/j.cmet.2021.07.010

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    sciencedirect.com/science/article/pii/S1550413121003260
  51. Jul 2021
  52. academic.oup.com academic.oup.com
    Untitled document
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      DOI: 10.1210/en.2018-00990

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    academic.oup.com/endo/article/160/2/430/5262410
  53. academic.oup.com academic.oup.com
    Untitled document
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      DOI: 10.1210/en.2018-00853

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    academic.oup.com/endo/article/160/5/1333/5427156
  54. May 2021
  55. www.sciencedirect.com www.sciencedirect.com
    Glycolytic ATP fuels phosphoinositide 3-kinase signaling to support effector T helper 17 cell responses
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      DOI: 10.1016/j.immuni.2021.04.008

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    sciencedirect.com/science/article/pii/S1074761321001709
  56. www.sciencedirect.com www.sciencedirect.com
    Anti-inflammatory Roles of Glucocorticoids Are Mediated by Foxp3+ Regulatory T Cells via a miR-342-Dependent Mechanism
    1
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      DOI: 10.1016/j.immuni.2020.07.002

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    sciencedirect.com/science/article/pii/S107476132030282X
  57. Apr 2021
  58. www.sciencedirect.com www.sciencedirect.com
    Developmental partitioning of SYK and ZAP70 prevents autoimmunity and cancer
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      DOI: 10.1016/j.molcel.2021.03.043

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    sciencedirect.com/science/article/pii/S1097276521002641
  59. Feb 2021
  60. link.springer.com link.springer.com
    Selective targeting of the androgen receptor-DNA binding domain by the novel antiandrogen SBF-1 and inhibition of the growth of prostate cancer cells
    1
    1. scibot 27 Feb 2021
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      DOI: 10.1007/s10637-020-01050-w

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    link.springer.com/article/10.1007/s10637-020-01050-w
  61. Sep 2020
  62. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Opposing p53 and mTOR/AKT promote an in vivo switch from apoptosis to senescence upon telomere shortening in zebrafish
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    1. scibot 13 Sep 2020
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      DOI: 10.7554/eLife.54935

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    ncbi.nlm.nih.gov/pmc/articles/PMC7237213/
  63. www.sciencedirect.com www.sciencedirect.com
    Low-Dose Vertical Inhibition of the RAF-MEK-ERK Cascade Causes Apoptotic Death of KRAS Mutant Cancers
    1
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      DOI: 10.1016/j.celrep.2020.107764

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    sciencedirect.com/science/article/pii/S2211124720307440
  64. onlinelibrary.wiley.com onlinelibrary.wiley.com
    FoxO3a requires BAF57, a subunit of chromatin remodeler SWI/SNF complex for induction of PUMA in a model of Parkinson’s disease
    1
    1. scibot 04 Sep 2020
      anti‐pFoxO1 (S256)

      DOI: 10.1111/jnc.14969

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  65. www.sciencedirect.com www.sciencedirect.com
    Angiotensin II-upregulated MAP kinase phosphatase-3 modulates FOXO1 and p21 in adrenocortical H295R cells
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  66. Jan 2020
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    Non-canonical mTORC2 Signaling Regulates Brown Adipocyte Lipid Catabolism through SIRT6-FoxO1
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      DOI: 10.1016/j.molcel.2019.07.023

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    Individual Cells Can Resolve Variations in Stimulus Intensity along the IGF-PI3K-AKT Signaling Axis
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      DOI: 10.1016/j.cels.2019.11.005

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  69. www.cell.com www.cell.com
    Acylglycerol Kinase Maintains Metabolic State and Immune Responses of CD8+ T Cells
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      DOI: 10.1016/j.cmet.2019.05.016

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    Pro-Survival Lipid Sphingosine-1-Phosphate Metabolically Programs T Cells to Limit Anti-tumor Activity
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      DOI: 10.1016/j.celrep.2019.07.044

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    WNT-Mediated Regulation of FOXO1 Constitutes a Critical Axis Maintaining Pubertal Mammary Stem Cell Homeostasis
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      DOI: 10.1016/j.devcel.2017.10.007

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  72. www.sciencedirect.com www.sciencedirect.com
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      DOI: 10.1016/j.celrep.2019.01.019

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  73. Nov 2018
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    In Vivo Decoding Mechanisms of the Temporal Patterns of Blood Insulin by the Insulin-AKT Pathway in the Liver
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    Super-Obese Patient-Derived iPSC Hypothalamic Neurons Exhibit Obesogenic Signatures and Hormone Responses
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  76. elifesciences.org elifesciences.org
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    CD38-NAD+Axis Regulates Immunotherapeutic Anti-Tumor T Cell Response
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  79. academic.oup.com academic.oup.com
    Timed Inhibition of Orexin System by Suvorexant Improved Sleep and Glucose Metabolism in Type 2 Diabetic db/db Mice
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  80. Nov 2017
  81. academic.oup.com academic.oup.com
    FoxO1 Promotes Mitophagy in the Podocytes of Diabetic Male Mice via the PINK1/Parkin Pathway
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      AB_329831

      Curator: @chewbeccax

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    Glucose Sensing by Skeletal Myocytes Couples Nutrient Signaling to Systemic Homeostasis
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    Low-Dose Dihydrotestosterone Drives Metabolic Dysfunction via Cytosolic and Nuclear Hepatic Androgen Receptor Mechanisms
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    Hippo Signaling Suppresses Cell Ploidy and Tumorigenesis through Skp2
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