Hypothesis

42 Matching Annotations

Apr 2025
52.53.155.43 52.53.155.43

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1. scibot 24 Apr 2025
  
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  RRID:AB_329842
  
  DOI: 10.5281/zenodo.15149909
  
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52.53.155.43/b645d57731bbad4da56bb2d7f98fed3df22d621f/PDF-html.html
Mar 2025
link.springer.com link.springer.com

A phase II trial of mTORC1/2 inhibition in STK11 deficient non small cell lung cancer

1
1. scibot 13 Mar 2025
  
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  RRID:AB_329842
  
  DOI: 10.1038/s41698-025-00838-4
  
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link.springer.com/article/10.1038/s41698-025-00838-4
Nov 2024
www.sciencedirect.com www.sciencedirect.com

Aberrant zonal recycling of germinal center B cells impairs appropriate selection in lupus

1
1. scibot 17 Nov 2024
  
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  RRID:AB_329842
  
  DOI: 10.1016/j.celrep.2024.114978
  
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sciencedirect.com/science/article/pii/S2211124724013299
Apr 2024
www.sciencedirect.com www.sciencedirect.com

Mutant FOXO1 controls an oncogenic network via enhancer accessibility

1
1. scibot 11 Apr 2024
  
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  RRID:AB_329842
  
  DOI: 10.1016/j.xgen.2024.100537
  
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sciencedirect.com/science/article/pii/S2666979X24000934
Oct 2023
www.sciencedirect.com www.sciencedirect.com

TRIM11 attenuates Treg cell differentiation by p62-selective autophagic degradation of AIM2

1
1. scibot 13 Oct 2023
  
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  RRID:AB_329842
  
  DOI: 10.1016/j.celrep.2023.113231
  
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sciencedirect.com/science/article/pii/S2211124723012433
Jul 2023
www.nature.com www.nature.com

Inhibition of AXL receptor tyrosine kinase enhances brown adipose tissue functionality in mice

1
1. scibot 15 Jul 2023
  
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  RRID:AB_329842
  
  DOI: 10.1038/s41467-023-39715-8
  
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nature.com/articles/s41467-023-39715-8
Apr 2023
www.sciencedirect.com www.sciencedirect.com

Optimal HSF1 activation in response to acute cold stress in BAT requires nuclear TXNIP

1
1. scibot 28 Apr 2023
  
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  RRID:AB_329842
  
  DOI: 10.1016/j.isci.2023.106538
  
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sciencedirect.com/science/article/pii/S2589004223006156
Mar 2023
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Metformin Prevents Endothelial Oxidative Stress and Microvascular Insulin Resistance during Obesity Development in Male Rats

1
1. scibot 05 Mar 2023
  
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  RRID:AB_329842
  
  DOI: 10.1152/ajpendo.00240.2021
  
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  Curator: @evieth
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8897003/
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FAK-mediated phosphorylation at Y464 regulates p85β nuclear translocation to promote tumorigenesis of ccRCC by repressing RB1 expression

1
1. scibot 02 Mar 2023
  
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  RRID:AB_329842
  
  DOI: 10.1016/j.celrep.2023.112188
  
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sciencedirect.com/science/article/pii/S2211124723001997
Jan 2023
www.sciencedirect.com www.sciencedirect.com

The deubiquitinase OTUD1 noncanonically suppresses Akt activation through its N-terminal intrinsically disordered region

1
1. scibot 02 Jan 2023
  
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  RRID:AB_329842
  
  DOI: 10.1016/j.celrep.2022.111916
  
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sciencedirect.com/science/article/pii/S2211124722018150
Dec 2022
www.sciencedirect.com www.sciencedirect.com

Discovery of a potent allosteric activator of DGKQ that ameliorates obesity-induced insulin resistance via the sn-1,2-DAG-PKCε signaling axis

1
1. scibot 17 Dec 2022
  
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  RRID:AB_329842
  
  DOI: 10.1016/j.cmet.2022.11.012
  
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sciencedirect.com/science/article/pii/S1550413122005034
Oct 2022
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

MYC-mediated silencing of miR-181a-5p promotes pathogenic Th17 responses by modulating AKT3-FOXO3 signaling

1
1. scibot 26 Oct 2022
  
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  RRID:AB_329842
  
  DOI: 10.1016/j.isci.2022.105176
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9557906/
Aug 2022
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

PH domain-mediated autoinhibition and oncogenic activation of Akt

1
1. scibot 31 Aug 2022
  
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  RRID:AB_329842
  
  DOI: 10.7554/eLife.80148
  
  Resource: (Cell Signaling Technology Cat# 9464, RRID:AB_329842)
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9417420/
www.sciencedirect.com www.sciencedirect.com

Hepatocyte Rap1a contributes to obesity- and statin-associated hyperglycemia

1
1. scibot 26 Aug 2022
  
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  RRID:AB_329842
  
  DOI: 10.1016/j.celrep.2022.111259
  
  Resource: (Cell Signaling Technology Cat# 9464, RRID:AB_329842)
  
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sciencedirect.com/science/article/pii/S2211124722010774
Jul 2022
52.53.155.43 52.53.155.43

British J Pharmacology - 2022 - Li - Maresin 1 intervention Reverses Experimental Pulmonary Arterial Hypertension in mice-html.html

1
1. scibot 29 Jul 2022
  
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  RRID:AB_329842
  
  DOI: 10.1111/bph.14208
  
  Resource: (Cell Signaling Technology Cat# 9464, RRID:AB_329842)
  
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52.53.155.43/eeb521b7ce9ed18aede2526ed77220c5d9e406f5/British J Pharmacology - 2022 - Li - Maresin 1 intervention Reverses Experimental Pulmonary Arterial Hypertension in mice-html.html
May 2022
www.nature.com www.nature.com

Convergent somatic mutations in metabolism genes in chronic liver disease

1
1. scibot 05 May 2022
  
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  RRID:AB_329842
  
  DOI: 10.1038/s41586-021-03974-6
  
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nature.com/articles/s41586-021-03974-6
Oct 2021
www.sciencedirect.com www.sciencedirect.com

PI3Kδ coordinates transcriptional, chromatin, and metabolic changes to promote effector CD8+ T cells at the expense of central memory

1
1. scibot 13 Oct 2021
  
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  RRID:AB_329842
  
  DOI: 10.1016/j.celrep.2021.109804
  
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sciencedirect.com/science/article/pii/S221112472101264X
Sep 2021
www.sciencedirect.com www.sciencedirect.com

KARATE: PKA-induced KRAS4B-RHOA-mTORC2 supercomplex phosphorylates AKT in insulin signaling and glucose homeostasis

1
1. scibot 22 Sep 2021
  
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  RRID:AB_329842
  
  DOI: 10.1016/j.molcel.2021.09.001
  
  Resource: (Cell Signaling Technology Cat# 9464, RRID:AB_329842)
  
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sciencedirect.com/science/article/pii/S1097276521007358
Aug 2021
www.sciencedirect.com www.sciencedirect.com

Delivery of membrane impermeable molecules to primary mouse T lymphocytes

1
1. scibot 18 Aug 2021
  
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  RRID:AB_329842
  
  DOI: 10.1016/j.xpro.2021.100757
  
  Resource: (Cell Signaling Technology Cat# 9464, RRID:AB_329842)
  
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sciencedirect.com/science/article/pii/S2666166721004639
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Targeting Aurora B kinase prevents and overcomes resistance to EGFR inhibitors in lung cancer by enhancing BIM- and PUMA-mediated apoptosis

1
1. scibot 16 Aug 2021
  
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  RRID:AB_329842
  
  DOI: 10.1016/j.ccell.2021.07.006
  
  Resource: (Cell Signaling Technology Cat# 9464, RRID:AB_329842)
  
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sciencedirect.com/science/article/pii/S1535610821003834
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Untitled document

1
1. scibot 09 Aug 2021
  
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  RRID:AB_329842
  
  DOI: 10.1016/j.devcel.2018.11.010
  
  Resource: (Cell Signaling Technology Cat# 9464, RRID:AB_329842)
  
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sciencedirect.com/science/article/pii/S1534580718309286
Jul 2021
www.sciencedirect.com www.sciencedirect.com

Microscopic image-based covariation network analysis for actin scaffold-modified insulin signaling

1
1. scibot 14 Jul 2021
  
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  RRID:AB_329842
  
  DOI: 10.1016/j.isci.2021.102724
  
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sciencedirect.com/science/article/pii/S2589004221006921
May 2021
www.sciencedirect.com www.sciencedirect.com

Glycolytic ATP fuels phosphoinositide 3-kinase signaling to support effector T helper 17 cell responses

1
1. scibot 12 May 2021
  
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  RRID:AB_329842
  
  DOI: 10.1016/j.immuni.2021.04.008
  
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sciencedirect.com/science/article/pii/S1074761321001709
Apr 2021
www.sciencedirect.com www.sciencedirect.com

A Cell-Autonomous Signature of Dysregulated Protein Phosphorylation Underlies Muscle Insulin Resistance in Type 2 Diabetes

1
1. scibot 29 Apr 2021
  
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  RRID:AB_329842
  
  DOI: 10.1016/j.cmet.2020.08.007
  
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sciencedirect.com/science/article/pii/S1550413120304204
Feb 2021
elifesciences.org elifesciences.org

The kinase PDK1 is critical for promoting T follicular helper cell differentiation

1
1. scibot 25 Feb 2021
  
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  RRID:AB_329842
  
  DOI: 10.7554/eLife.61406
  
  Resource: (Cell Signaling Technology Cat# 9464, RRID:AB_329842)
  
  Curator: @Naa003
  
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  RRID:AB_329842 RRIDCUR:Validated
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elifesciences.org/articles/61406
Nov 2020
www.sciencedirect.com www.sciencedirect.com

Overcoming Adaptive Resistance to KRAS and MEK Inhibitors by Co-targeting mTORC1/2 Complexes in Pancreatic Cancer

1
1. scibot 24 Nov 2020
  
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  RRID:AB_329842
  
  DOI: 10.1016/j.xcrm.2020.100131
  
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  RRID:AB_329842 RRIDCUR:Validated
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sciencedirect.com/science/article/pii/S2666379120301737
www.sciencedirect.com www.sciencedirect.com

Cyclin D3 Governs Clonal Expansion of Dark Zone Germinal Center B Cells

1
1. scibot 24 Nov 2020
  
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  RRID:AB_329842
  
  DOI: 10.1016/j.celrep.2020.108403
  
  Resource: (Cell Signaling Technology Cat# 9464, RRID:AB_329842)
  
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  RRID:AB_329842 RRIDCUR:Validated
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sciencedirect.com/science/article/pii/S2211124720313929
Oct 2020
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

SWELL1 regulates skeletal muscle cell size, intracellular signaling, adiposity and glucose metabolism

1
1. scibot 13 Oct 2020
  
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  RRID:AB_329842
  
  DOI: 10.7554/eLife.58941
  
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  Curator: @evieth
  
  SciCrunch record: RRID:AB_329842
  
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  RRID:AB_329842 RRIDCUR:Validated
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ncbi.nlm.nih.gov/pmc/articles/PMC7541086/
www.sciencedirect.com www.sciencedirect.com

The Lipid Handling Capacity of Subcutaneous Fat Is Programmed by mTORC2 during Development

1
1. scibot 08 Oct 2020
  
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  RRID:AB_329842
  
  DOI: 10.1016/j.celrep.2020.108223
  
  Resource: (Cell Signaling Technology Cat# 9464, RRID:AB_329842)
  
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  RRID:AB_329842 RRIDCUR:Validated
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sciencedirect.com/science/article/pii/S2211124720312122
link.springer.com link.springer.com

Skeletal muscle IGF-1 is lower at rest and after resistance exercise in humans with obesity

1
1. scibot 01 Oct 2020
  
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  RRID:AB_329842
  
  DOI: 10.1007/s00421-020-04509-z
  
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  RRID:AB_329842 RRIDCUR:Validated
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link.springer.com/article/10.1007/s00421-020-04509-z
Sep 2020
www.sciencedirect.com www.sciencedirect.com

Low-Dose Vertical Inhibition of the RAF-MEK-ERK Cascade Causes Apoptotic Death of KRAS Mutant Cancers

1
1. scibot 09 Sep 2020
  
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  RRID:AB_329842
  
  DOI: 10.1016/j.celrep.2020.107764
  
  Resource: (Cell Signaling Technology Cat# 9464, RRID:AB_329842)
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:AB_329842
  
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  RRID:AB_329842 RRIDCUR:Validated
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sciencedirect.com/science/article/pii/S2211124720307440
Jan 2020
www.sciencedirect.com www.sciencedirect.com

Non-canonical mTORC2 Signaling Regulates Brown Adipocyte Lipid Catabolism through SIRT6-FoxO1

1
1. scibot 13 Jan 2020
  
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  RRID:AB_329842
  
  DOI: 10.1016/j.molcel.2019.07.023
  
  Resource: (Cell Signaling Technology Cat# 9464, RRID:AB_329842)
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:AB_329842
  
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  RRID:AB_329842 RRIDCUR:Validated
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sciencedirect.com/science/article/pii/S1097276519305532
www.sciencedirect.com www.sciencedirect.com

CD146 Regulates Growth Factor-Induced mTORC2 Activity Independent of the PI3K and mTORC1 Pathways

1
1. scibot 13 Jan 2020
  
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  RRID:AB_329842
  
  DOI: 10.1016/j.celrep.2019.09.047
  
  Resource: (Cell Signaling Technology Cat# 9464, RRID:AB_329842)
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:AB_329842
  
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  RRID:AB_329842 RRIDCUR:Validated
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sciencedirect.com/science/article/pii/S2211124719312355
www.sciencedirect.com www.sciencedirect.com

WNT-Mediated Regulation of FOXO1 Constitutes a Critical Axis Maintaining Pubertal Mammary Stem Cell Homeostasis

1
1. scibot 13 Jan 2020
  
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  RRID:AB_329842
  
  DOI: 10.1016/j.devcel.2017.10.007
  
  Resource: (Cell Signaling Technology Cat# 9464, RRID:AB_329842)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:AB_329842
  
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  RRID:AB_329842 RRIDCUR:Validated
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sciencedirect.com/science/article/pii/S1534580717308201
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Untitled document

1
1. scibot 13 Jan 2020
  
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  RRID:AB_329842
  
  DOI: 10.1016/j.celrep.2019.01.066
  
  Resource: (Cell Signaling Technology Cat# 9464, RRID:AB_329842)
  
  Curator: @evieth
  
  SciCrunch record: RRID:AB_329842
  
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  RRID:AB_329842 RRIDCUR:Validated
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sciencedirect.com/science/article/pii/S2211124719300956
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Untitled document

1
1. scibot 13 Jan 2020
  
  in Public
  
  RRID:AB_329842
  
  DOI: 10.1016/j.celrep.2019.02.081
  
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  Curator: @ethanbadger
  
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Akt Kinase Activation Mechanisms Revealed Using Protein Semisynthesis

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Knockout of USP19 Deubiquitinating Enzyme Prevents Muscle Wasting by Modulating Insulin and Glucocorticoid Signaling

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B Cell Receptor and CD40 Signaling Are Rewired for Synergistic Induction of the c-Myc Transcription Factor in Germinal Center B Cells

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Untitled document

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Nov 2017
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The Kinase mTORC1 Promotes the Generation and Suppressive Function of Follicular Regulatory T Cells

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Hippo Signaling Suppresses Cell Ploidy and Tumorigenesis through Skp2

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