58 Matching Annotations
  1. Nov 2026
  2. www.sciencedirect.com www.sciencedirect.com
    RAStoERK: A reference interaction atlas for insights into signaling and disease
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S2211124726012805
  3. Sep 2026
  4. link.springer.com link.springer.com
    Da chuanxiong formula improves vascular remodeling via promoting angiogenesis and vasodilation mediated by PI3K/Akt/eNOS signaling
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    link.springer.com/article/10.1007/s11011-026-01974-x
  5. Aug 2026
  6. www.sciencedirect.com www.sciencedirect.com
    Gut microbiota and uric acid excretion signaling in pathogenesis of hyperuricemia and acute gouty arthritis
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S2589004226024508
  7. www.sciencedirect.com www.sciencedirect.com
    Melanoma exosomal hsa-miR-221-5p suppresses keratinocyte LL-37 to promote tumor progression
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S2211124726009150
  8. www.sciencedirect.com www.sciencedirect.com
    Gut commensal Olsenella profusa promotes endometriosis via lysophosphatidylcholine metabolite
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S2666379126003873
  9. May 2026
  10. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    MicroRNA-200s attenuate demyelination caused by Angiostrongylus cantonensis in a mouse model by targeting phosphatase and tensin homolog
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    pmc.ncbi.nlm.nih.gov/articles/PMC13211809/
  11. link.springer.com link.springer.com
    Celecoxib potentiates ribociclib-induced apoptosis and anti-tumor activity by co-targeting COX-2/NF-κB and PI3K/AKT/mTOR pathways in hormone receptor-positive/HER2-negative breast cancer
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    link.springer.com/article/10.1007/s10495-026-02340-z
  12. Jan 2026
  13. link.springer.com link.springer.com
    Repression of Polycomb Group Factor 1 Inhibits EMT Progression in Colon Cancers Cells via Wnt/β-Catenin and PI3K/Akt/mTOR Signaling Pathway
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    link.springer.com/article/10.1007/s10620-025-09641-4
  14. Oct 2025
  15. www.sciencedirect.com www.sciencedirect.com
    Absence of BCAP in myeloid cells abrogates M2 macrophage differentiation and promotes anti-tumor immunity
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S2589004225019844
  16. www.sciencedirect.com www.sciencedirect.com
    Adipose m6A reader YTHDF2 promotes obesity, insulin resistance, and liver steatosis by suppressing β-adrenergic signaling and lipolysis
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S2211124725012161
  17. Sep 2025
  18. link.springer.com link.springer.com
    4-aminopyridine exerts anxiolytic and pro-cognitive effects in mice model of medial prefrontal cortex ischemia
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    link.springer.com/article/10.1007/s11011-025-01695-7
  19. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Insulin potentiates mechanical responses in small dorsal root ganglion neurons by increasing the sensitization of TRPV4 channels
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    pmc.ncbi.nlm.nih.gov/articles/PMC12379057/
  20. Aug 2025
  21. www.sciencedirect.com www.sciencedirect.com
    Tumor-resident probiotic Clostridium butyricum improves aPD-1 efficacy in colorectal cancer models by inhibiting IL-6-mediated immunosuppression
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S1535610825003186
  22. Jul 2025
  23. link.springer.com link.springer.com
    Using computational pharmacology and experimental verification to decode mechanism of Qing-Wei-San in treating periodontitis
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    link.springer.com/article/10.1186/s12906-025-04967-y
  24. Jun 2025
  25. www.sciencedirect.com www.sciencedirect.com
    PM2.5 exposure-induced senescence-associated secretory phenotype in airway smooth muscle cells contributes to airway remodeling
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S0269749124003889
  26. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    In Vitro Anticancer Activity of Phytol on Human Non-Small Cell Lung Cancer A549 Cells
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    pmc.ncbi.nlm.nih.gov/articles/PMC12141803/
  27. journals.sagepub.com journals.sagepub.com
    In Vitro Anticancer Activity of Phytol on Human Non-Small Cell Lung Cancer A549 Cells
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    journals.sagepub.com/doi/full/10.1177/15347354251344592
  28. May 2025
  29. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Loss of neurofibromin induces inflammatory macrophage phenotypic switch and retinal neovascularization via GLUT1 activation
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    pmc.ncbi.nlm.nih.gov/articles/PMC12184535/
  30. Apr 2025
  31. www.jneurosci.org www.jneurosci.org
    Cell adhesion molecule protocadherin-γC5 ameliorates Aβ plaque pathogenesis by modulating astrocyte function in Alzheimer’s disease
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    jneurosci.org/content/45/10/e0967242025
  32. Dec 2024
  33. www.sciencedirect.com www.sciencedirect.com
    Phase separation of chimeric antigen receptor promotes immunological synapse maturation and persistent cytotoxicity
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S107476132400520X
  34. www.sciencedirect.com www.sciencedirect.com
    B7H6 is the predominant activating ligand driving natural killer cell-mediated killing in patients with liquid tumours: evidence from clinical, in silico, in vitro, and in vivo studies
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S235239642400495X
  35. Sep 2024
  36. physoc.onlinelibrary.wiley.com physoc.onlinelibrary.wiley.com
    Intracerebroventricular insulin injection acutely normalizes the augmented exercise pressor reflex in male rats with type 2 diabetes mellitus
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    physoc.onlinelibrary.wiley.com/doi/10.1113/JP286715
  37. Aug 2024
  38. www.sciencedirect.com www.sciencedirect.com
    Integrative plasma and fecal metabolomics identify functional metabolites in adenoma-colorectal cancer progression and as early diagnostic biomarkers
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S1535610824002708
  39. Jul 2024
  40. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Energy‑stress‑mediated activation of AMPK sensitizes MPS1 kinase inhibition in triple‑negative breast cancer
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    ncbi.nlm.nih.gov/pmc/articles/PMC11223027/
  41. Feb 2024
  42. link.springer.com link.springer.com
    Integrating Network Pharmacology and Experimental Verification to Explore the Pharmacological Mechanisms of Radix Paeoniae Rubra Against Glioma
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    link.springer.com/article/10.1007/s12010-024-04887-6
  43. Dec 2023
  44. www.sciencedirect.com www.sciencedirect.com
    KDM5B predicts temozolomide-resistant subclones in glioblastoma
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S2589004223026731
  45. Oct 2023
  46. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Bilirubin impacts microglial autophagy via the Akt–mTOR signaling pathway
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    onlinelibrary.wiley.com/doi/full/10.1111/jnc.15984
  47. Aug 2023
  48. www.sciencedirect.com www.sciencedirect.com
    PLEKHS1 drives PI3Ks and remodels pathway homeostasis in PTEN-null prostate
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S1097276523005580
  49. Jul 2023
  50. www.sciencedirect.com www.sciencedirect.com
    GSDMA3 deficiency reprograms cellular metabolism and modulates BCR signaling in murine B cells
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S2589004223014189
  51. 52.53.155.43 52.53.155.43
    PLEKHS1 drives PI3Ks and remodels pathway homeostasis in PTEN-null prostate
    2
    Visit annotations in context

    Tags

    Annotators

    URL

    52.53.155.43/47cafcf0b0c101b9655865f446b83a64cc86d1a1/2023.05.18.541123v1.full-html.html
  52. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Mechanical manipulation of cancer cell tumorigenicity via heat shock protein signaling
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    ncbi.nlm.nih.gov/pmc/articles/PMC10328411/
  53. Jun 2023
  54. www.sciencedirect.com www.sciencedirect.com
    Identification and validation of Rab11a in Rat orofacial inflammatory pain model induced by CFA
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S0197018623000785
  55. Apr 2023
  56. www.sciencedirect.com www.sciencedirect.com
    Design of Diversified Chimeric Antigen Receptors Through Rational Module Recombination
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S2589004223006065
  57. Feb 2023
  58. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Neuroprotective Effects of a Multi-Herbal Extract on Axonal and Synaptic Disruption in Vitro and Cognitive Impairment in Vivo
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    ncbi.nlm.nih.gov/pmc/articles/PMC9912829/
  59. Jan 2023
  60. journals.lww.com journals.lww.com
    PTEN inhibitor bisperoxovanadium protects against... : Neural Regeneration Research
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    journals.lww.com/nrronline/Fulltext/2023/07000/PTEN_inhibitor_bisperoxovanadium_protects_against.36.aspx
  61. Dec 2022
  62. www.sciencedirect.com www.sciencedirect.com
    The insulin and IGF signaling pathway sustains breast cancer stem cells by IRS2/PI3K-mediated regulation of MYC
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S2211124722016424
  63. Sep 2022
  64. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Hyperuricemia contributes to glucose intolerance of hepatic inflammatory macrophages and impairs the insulin signaling pathway via IRS2-proteasome degradation
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    ncbi.nlm.nih.gov/pmc/articles/PMC9513153/
  65. Mar 2022
  66. www.sciencedirect.com www.sciencedirect.com
    Methylene-bridge tryptophan fatty acylation regulates PI3K-AKT signaling and glucose uptake
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S2211124722002455
  67. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Proanthocyanidins Inhibit the Transmission of Spinal Pain Information Through a Presynaptic Mechanism in a Mouse Inflammatory Pain Model
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    ncbi.nlm.nih.gov/pmc/articles/PMC8850919/
  68. Feb 2022
  69. www.sciencedirect.com www.sciencedirect.com
    Stanniocalcin2 inhibits the epithelial-mesenchymal transition and invasion of trophoblasts via activation of autophagy under high-glucose conditions
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S0303720722000454
  70. Dec 2021
  71. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Aging Does Not Exacerbate Muscle Loss During Denervation and Lends Unique Muscle-Specific Atrophy Resistance With Akt Activation
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    ncbi.nlm.nih.gov/pmc/articles/PMC8669767/
  72. May 2021
  73. www.sciencedirect.com www.sciencedirect.com
    The E3 ligase TRAF4 Promotes IGF Signaling by Mediating Atypical Ubiquitination of IRS-1
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S0021925821005287
  74. Feb 2021
  75. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    BPS Publications
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.15047
  76. onlinelibrary.wiley.com onlinelibrary.wiley.com
    MicroRNA‐34a causes ceramide accumulation and effects insulin signaling pathway by targeting ceramide kinase (CERK) in aging skeletal muscle
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    onlinelibrary.wiley.com/doi/10.1002/jcb.29312
  77. Sep 2020
  78. www.sciencedirect.com www.sciencedirect.com
    Loratadine, an antihistamine drug, exhibits anti-inflammatory activity through suppression of the NF-kB pathway
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S0006295220301775
  79. cancerres.aacrjournals.org cancerres.aacrjournals.org
    CoA Synthase (COASY) mediates radiation resistance via PI3K signaling in rectal cancer
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    cancerres.aacrjournals.org/content/80/2/334
  80. www.sciencedirect.com www.sciencedirect.com
    Multiple Signaling Roles of CD3ε and Its Application in CAR-T Cell Therapy
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S0092867420308837
  81. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    BPS Publications
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.15042
  82. www.mdpi.com www.mdpi.com
    Looking for a Better Characterization of Triple-Negative Breast Cancer by Means of Circulating Tumor Cells
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    mdpi.com/2077-0383/9/2/353
  83. stke.sciencemag.org stke.sciencemag.org
    Blocking EGFR palmitoylation suppresses PI3K signaling and mutant KRAS lung tumorigenesis
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    stke.sciencemag.org/content/13/621/eaax2364
  84. Jan 2020
  85. www.sciencedirect.com www.sciencedirect.com
    PD-L1:CD80 Cis-Heterodimer Triggers the Co-stimulatory Receptor CD28 While Repressing the Inhibitory PD-1 and CTLA-4 Pathways
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S1074761319304613
  86. academic.oup.com academic.oup.com
    Perioperative infusion of glucagon like peptide-1 prevents insulin resistance after surgical trauma in female pigs
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    academic.oup.com/endo/article/160/12/2892/5581188
  87. onlinelibrary.wiley.com onlinelibrary.wiley.com
    LncRNA MEG3 contributes to adenosine‐induced cytotoxicity in hepatoma HepG2 cells by downregulated ILF3 and autophagy inhibition via regulation PI3K‐AKT‐mTOR and beclin‐1 signaling pathway
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    onlinelibrary.wiley.com/doi/full/10.1002/jcb.29123
  88. link.springer.com link.springer.com
    Untitled document
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    link.springer.com/article/10.1007/s12640-018-9991-2
  89. Nov 2018
  90. content.iospress.com content.iospress.com
    NO-Dependent Akt Inactivation by S-Nitrosylation as a Possible Mechanism of STZ-Induced Neuronal Insulin Resistance
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    content.iospress.com/articles/journal-of-alzheimers-disease/jad180284
  91. www.sciencedirect.com www.sciencedirect.com
    Antigen-Presenting Cell-Intrinsic PD-1 Neutralizes PD-L1 in cis to Attenuate PD-1 Signaling in T Cells
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S2211124718309641
  92. Nov 2017
  93. academic.oup.com academic.oup.com
    Aldose Reductase Mediates NLRP3 Inflammasome–Initiated Innate Immune Response in Hyperglycemia-Induced Thp1 Monocytes and Male Mice
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    academic.oup.com/endo/article/158/10/3661/4049499/Aldose-Reductase-Mediates-NLRP3-Inflammasome