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  1. Last 7 days
  2. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    p21 regulates expression of ECM components and promotes pulmonary fibrosis via CDK4 and Rb
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    1. scibot 21 Nov 2024
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      DOI: 10.1038/s44318-024-00246-7

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    pmc.ncbi.nlm.nih.gov/articles/PMC11574164/
  3. Jul 2024
  4. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A Kinome-Wide Synthetic Lethal CRISPR/Cas9 Screen Reveals That mTOR Inhibition Prevents Adaptive Resistance to CDK4/CDK6 Blockade in HNSCC
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    1. scibot 31 Jul 2024
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      DOI: 10.1158/2767-9764.CRC-24-0247

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    ncbi.nlm.nih.gov/pmc/articles/PMC11284272/
  5. onlinelibrary.wiley.com onlinelibrary.wiley.com
    The SASP factor IL-6 sustains cell-autonomous senescent cells via a cGAS-STING-NFκB intracrine senescent noncanonical pathway
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    1. scibot 23 Jul 2024
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      DOI: 10.1111/acel.14258

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    onlinelibrary.wiley.com/doi/10.1111/acel.14258
  6. May 2024
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    Molecular subtypes of neuroendocrine carcinomas: A cross-tissue classification framework based on five transcriptional regulators
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    1. scibot 24 May 2024
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      DOI: 10.1016/j.ccell.2024.05.002

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    sciencedirect.com/science/article/pii/S1535610824001636
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    Combined CDK4/6 and ERK1/2 inhibition enhances anti-tumor activity in NF1-associated plexiform neurofibroma
    1
    1. scibot 02 May 2024
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      DOI: 10.1158/1078-0432.CCR-22-2854

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    ncbi.nlm.nih.gov/pmc/articles/PMC11060649/
  9. Mar 2024
  10. www.sciencedirect.com www.sciencedirect.com
    CDK-independent role of D-type cyclins in regulating DNA mismatch repair
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    1. scibot 08 Mar 2024
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      DOI: 10.1016/j.molcel.2024.02.010

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    2. scibot 08 Mar 2024
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      DOI: 10.1016/j.molcel.2024.02.010

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    sciencedirect.com/science/article/pii/S1097276524001291
  11. Aug 2023
  12. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Kinase Suppressor of RAS 1 (KSR1) Maintains the Transformed Phenotype of BRAFV600E Mutant Human Melanoma Cells
    1
    1. scibot 01 Aug 2023
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      DOI: 10.3390/ijms241411821

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    ncbi.nlm.nih.gov/pmc/articles/PMC10380721/
  13. Apr 2023
  14. www.sciencedirect.com www.sciencedirect.com
    Targeting protein tyrosine phosphatases for CDK6-induced immunotherapy resistance
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    1. scibot 06 Apr 2023
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      DOI: 10.1016/j.celrep.2023.112314

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    sciencedirect.com/science/article/pii/S221112472300325X
  15. Oct 2022
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    Validation of a non-oncogene encoded vulnerability to exportin 1 inhibition in pediatric renal tumors
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    1. scibot 04 Oct 2022
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      DOI: 10.1016/j.medj.2022.09.002

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    sciencedirect.com/science/article/pii/S2666634022004032
  17. Mar 2022
  18. www.sciencedirect.com www.sciencedirect.com
    CDK/cyclin dependencies define extreme cancer cell-cycle heterogeneity and collateral vulnerabilities
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    1. scibot 02 Mar 2022
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      DOI: 10.1016/j.celrep.2022.110448

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    sciencedirect.com/science/article/pii/S2211124722001759
  19. Nov 2021
  20. www.sciencedirect.com www.sciencedirect.com
    Tumor suppressor p53 promotes ferroptosis in oxidative stress conditions independent of modulation of ferroptosis by p21, CDKs, Rb and E2F.
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    1. scibot 09 Nov 2021
      9307S

      DOI: 10.1016/j.jbc.2021.101365

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    sciencedirect.com/science/article/pii/S0021925821011716
  21. Aug 2021
  22. www.sciencedirect.com www.sciencedirect.com
    Crosstalk between Drp1 phosphorylation sites during mitochondrial remodeling and their impact on metabolic adaptation
    1
    1. scibot 25 Aug 2021
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      DOI: 10.1016/j.celrep.2021.109565

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    sciencedirect.com/science/article/pii/S2211124721009992
  23. Jul 2021
  24. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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    1. scibot 30 Jul 2021
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      DOI: 10.1016/j.ccell.2018.08.015

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    ncbi.nlm.nih.gov/pmc/articles/PMC6179967/
  25. Jun 2021
  26. www.sciencedirect.com www.sciencedirect.com
    Targeting p130Cas- and microtubule-dependent MYC regulation sensitizes pancreatic cancer to ERK MAPK inhibition
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    1. scibot 30 Jun 2021
      RRID:AB_330015

      DOI: 10.1016/j.celrep.2021.109291

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    sciencedirect.com/science/article/pii/S2211124721006628
  27. Apr 2021
  28. www.sciencedirect.com www.sciencedirect.com
    An Organoid Biobank of Neuroendocrine Neoplasms Enables Genotype-Phenotype Mapping
    1
    1. scibot 24 Apr 2021
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      DOI: 10.1016/j.cell.2020.10.023

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    sciencedirect.com/science/article/pii/S0092867420313878
  29. Mar 2021
  30. www.sciencedirect.com www.sciencedirect.com
    An Embryonic Diapause-like Adaptation with Suppressed Myc Activity Enables Tumor Treatment Persistence
    1
    1. scibot 01 Mar 2021
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      DOI: 10.1016/j.ccell.2020.12.002

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    sciencedirect.com/science/article/pii/S1535610820306097
  31. Oct 2020
  32. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    A Marine Alkaloid, Ascomylactam A, Suppresses Lung Tumorigenesis via Inducing Cell Cycle G1/S Arrest through ROS/Akt/Rb Pathway
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    1. scibot 03 Oct 2020
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      DOI: 10.3390/md18100494

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    pubmed.ncbi.nlm.nih.gov/32992455/
  33. Sep 2020
  34. www.sciencedirect.com www.sciencedirect.com
    Scavenging of Labile Heme by Hemopexin Is a Key Checkpoint in Cancer Growth and Metastases
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    1. scibot 26 Sep 2020
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      DOI: 10.1016/j.celrep.2020.108181

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    sciencedirect.com/science/article/pii/S2211124720311700
  35. www.sciencedirect.com www.sciencedirect.com
    CDK4/6 Inhibitors Impair Recovery from Cytotoxic Chemotherapy in Pancreatic Adenocarcinoma
    1
    1. scibot 16 Sep 2020
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      DOI: 10.1016/j.ccell.2020.01.007

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    sciencedirect.com/science/article/pii/S1535610820300465
  36. www.sciencedirect.com www.sciencedirect.com
    Endogenous Cyclin D1 Promotes the Rate of Onset and Magnitude of Mitogenic Signaling via Akt1 Ser473 Phosphorylation
    1
    1. scibot 16 Sep 2020
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      DOI: 10.1016/j.celrep.2020.108151

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    sciencedirect.com/science/article/pii/S2211124720311402
  37. www.cell.com www.cell.com
    The Oncogenic Transcription Factor RUNX1/ETO Corrupts Cell Cycle Regulation to Drive Leukemic Transformation
    1
    1. scibot 04 Sep 2020
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      DOI: 10.1016/j.ccell.2018.08.015

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    cell.com/cancer-cell/fulltext/S1535-6108(18)30375-1
  38. Jan 2020
  39. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    MicroRNA-1-Mediated Inhibition of Cardiac Fibroblast Proliferation Through Targeting Cyclin D2 and CDK6
    1
    1. scibot 13 Jan 2020
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      DOI: 10.3389/fcvm.2019.00065

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    ncbi.nlm.nih.gov/pmc/articles/PMC6533459/
  40. Nov 2018
  41. www.ncbi.nlm.nih.govhttp: www.ncbi.nlm.nih.govhttp:
    Untitled document
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    1. scibot 05 Nov 2018
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    ncbi.nlm.nih.govhttp://europepmc.org/articles/PMC6179967/
  42. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Constitutive Cdk2 activity promotes aneuploidy while altering the spindle assembly and tetraploidy checkpoints
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    1. scibot 05 Nov 2018
      p-Rb 780

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    ncbi.nlm.nih.gov/pmc/articles/PMC3635462/
  43. www.sciencedirect.com www.sciencedirect.com
    Untitled document
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    1. scibot 05 Nov 2018
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    sciencedirect.com/science/article/pii/S1535610818303751
  44. www.sciencedirect.com www.sciencedirect.com
    β-Hydroxybutyrate Prevents Vascular Senescence through hnRNP A1-Mediated Upregulation of Oct4
    1
    1. scibot 05 Nov 2018
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      Curator: @Jmenke

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    sciencedirect.com/science/article/pii/S1097276518306051
  45. www.sciencedirect.com www.sciencedirect.com
    An Acquired Vulnerability of Drug-Resistant Melanoma with Therapeutic Potential
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    1. scibot 05 Nov 2018
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    sciencedirect.com/science/article/pii/S0092867418305051
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    Cell-Cycle Proteins Control Production of Neutrophil Extracellular Traps
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    1. scibot 05 Nov 2018
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    sciencedirect.com/science/article/pii/S1534580717308262