24 Matching Annotations
  1. Sep 2024
  2. www.sciencedirect.com www.sciencedirect.com
    IGFBP7 is upregulated in islets from T2D donors and reduces insulin secretion
    1
    1. scibot 25 Sep 2024
      AB_330222

      DOI: 10.1016/j.isci.2024.110767

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    sciencedirect.com/science/article/pii/S2589004224019928
  3. Aug 2024
  4. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Fam49b dampens TCR signal strength to regulate survival of positively selected thymocytes and peripheral T cells
    1
    1. scibot 23 Aug 2024
      RRID:AB_330222

      DOI: 10.7554/eLife.76940

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    ncbi.nlm.nih.gov/pmc/articles/PMC11333044/
  5. Jul 2024
  6. 52.53.155.43 52.53.155.43
    A dual role for Integrin α6β4 in modulating hereditary neuropathy with liability to pressure palsies
    1
    1. scibot 23 Jul 2024
      RRID:AB_330222

      DOI: 10.1111/jnc.14295

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    52.53.155.43/0bf5a35474616f8cd124d354ba59ef8784f885ac/A_dual_role_for_Integrin_64_in_modulat-html.html
  7. Feb 2024
  8. www.science.org www.science.org
    RHOAL57V drives the development of diffuse gastric cancer through IGF1R-PAK1-YAP1 signaling
    1
    1. scibot 16 Feb 2024
      RRID AB_330222

      DOI: 10.1126/scisignal.adg5289

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    science.org/doi/10.1126/scisignal.adg5289
  9. Jan 2024
  10. www.science.org www.science.org
    RHOAL57V drives the development of diffuse gastric cancer through IGF1R-PAK1-YAP1 signaling
    1
    1. scibot 20 Jan 2024
      RRID:AB_330222

      DOI: 10.1126/scisignal.adg5289

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      Curator: @evieth

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    science.org/doi/10.1126/scisignal.adg5289
  11. Nov 2023
  12. www.sciencedirect.com www.sciencedirect.com
    PAK1-dependent mechanotransduction enables myofibroblast nuclear adaptation and chromatin organization during fibrosis
    1
    1. scibot 28 Nov 2023
      RRID:AB_330222

      DOI: 10.1016/j.celrep.2023.113414

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    sciencedirect.com/science/article/pii/S2211124723014262
  13. Aug 2023
  14. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The Evaluation of Rac1 Signaling as a Potential Therapeutic Target of Alzheimer’s Disease
    1
    1. scibot 16 Aug 2023
      RRID:AB_330222

      DOI: 10.3390/ijms241511880

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    ncbi.nlm.nih.gov/pmc/articles/PMC10418761/
  15. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    PAK1 contributes to cerebral ischemia/reperfusion injury by regulating the blood-brain barrier integrity
    1
    1. scibot 02 Aug 2023
      RRID:AB_330222

      DOI: 10.1016/j.isci.2023.107333

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    ncbi.nlm.nih.gov/pmc/articles/PMC10387573/
  16. Jun 2022
  17. www.nature.com www.nature.com
    Phosphoproteomic of the acetylcholine pathway enables discovery of the PKC-β-PIX-Rac1-PAK cascade as a stimulatory signal for aversive learning
    1
    1. scibot 04 Jun 2022
      RRID:AB_330222

      DOI: 10.1038/s41380-022-01643-2

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    nature.com/articles/s41380-022-01643-2
  18. Apr 2022
  19. www.sciencedirect.com www.sciencedirect.com
    Lyso-PAF, a biologically inactive phospholipid, contributes to RAF1 activation
    1
    1. scibot 13 Apr 2022
      RRID:AB_330222

      DOI: 10.1016/j.molcel.2022.03.026

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    sciencedirect.com/science/article/pii/S1097276522002647
  20. www.sciencedirect.com www.sciencedirect.com
    Structure-based design of CDC42 effector interaction inhibitors for the treatment of cancer
    1
    1. scibot 07 Apr 2022
      RRID:AB_330222

      DOI: 10.1016/j.celrep.2022.110641

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    sciencedirect.com/science/article/pii/S221112472200393X
  21. Sep 2021
  22. www.sciencedirect.com www.sciencedirect.com
    Optimizing metastatic-cascade-dependent Rac1 targeting in breast cancer: Guidance using optical window intravital FRET imaging
    1
    1. scibot 21 Sep 2021
      RRID:AB_330222

      DOI: 10.1016/j.celrep.2021.109689

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    sciencedirect.com/science/article/pii/S2211124721011360
  23. journals.plos.org journals.plos.org
    A kinase-independent function of PAK is crucial for pathogen-mediated actin remodelling
    1
    1. scibot 08 Sep 2021
      2602

      DOI: 10.1371/journal.ppat.1009902

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    journals.plos.org/plospathogens/article
  24. Jul 2021
  25. mbio.asm.org mbio.asm.org
    Pathogenic Escherichia coli Hijacks GTPase-Activated p21-Activated Kinase for Actin Pedestal Formation
    1
    1. scibot 29 Jul 2021
      PAK1

      DOI: 10.1128/mBio.01876-19

      Resource: (Cell Signaling Technology Cat# 2602, RRID:AB_330222)

      Curator: @Naa003

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    mbio.asm.org/content/10/4/e01876-19
  26. Apr 2021
  27. www.jneurosci.org www.jneurosci.org
    PAK1 positively regulates oligodendrocyte morphology and myelination.
    1
    1. scibot 08 Apr 2021
      RRID:AB_330222

      DOI: 10.1523/JNEUROSCI.0229-20.2021

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      RRIDCUR:Validated RRID:AB_330222
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    jneurosci.org/content/41/9/1864
  28. Mar 2021
  29. www.sciencedirect.com www.sciencedirect.com
    Endothelin-1 drives invadopodia and interaction with mesothelial cells through ILK
    1
    1. scibot 03 Mar 2021
      Rabbit polyclonal anti-PAK1

      DOI: 10.1016/j.celrep.2021.108800

      Resource: (Cell Signaling Technology Cat# 2602, RRID:AB_330222)

      Curator: @Naa003

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    sciencedirect.com/science/article/pii/S2211124721001145
  30. Dec 2020
  31. physoc.onlinelibrary.wiley.com physoc.onlinelibrary.wiley.com
    Insulin‐stimulated glucose uptake partly relies on p21‐activated kinase 2 (PAK2), but not PAK1, in mouse skeletal muscle
    1
    1. scibot 07 Dec 2020
      AB_330 222

      DOI: 10.1113/JP280294

      Resource: (Cell Signaling Technology Cat# 2602, RRID:AB_330222)

      Curator: @Naa003

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      Curator comments: Anti-PAK1 Antibody, Unconjugated Cell Signaling Technology Cat# 2602

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    physoc.onlinelibrary.wiley.com/doi/10.1113/JP280294
  32. Sep 2020
  33. www.sciencedirect.com www.sciencedirect.com
    The Protein Arginine Methyltransferase PRMT8 and Substrate G3BP1 Control Rac1-PAK1 Signaling and Actin Cytoskeleton for Dendritic Spine Maturation
    1
    1. scibot 06 Sep 2020
      RRID:AB_330222

      DOI: 10.1016/j.celrep.2020.107744

      Resource: (Cell Signaling Technology Cat# 2602, RRID:AB_330222)

      Curator: @ethanbadger

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      RRID:AB_330222 RRIDCUR:Validated
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    sciencedirect.com/science/article/pii/S2211124720307245
  34. physoc.onlinelibrary.wiley.com physoc.onlinelibrary.wiley.com
    The p21‐activated kinase 2 (PAK2), but not PAK1, regulates contraction‐stimulated skeletal muscle glucose transport
    1
    1. scibot 05 Sep 2020
      AB_330222

      DOI: 10.14814/phy2.14460

      Resource: (Cell Signaling Technology Cat# 2602, RRID:AB_330222)

      Curator: @ethanbadger

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      RRIDCUR:Validated RRID:AB_330222
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    physoc.onlinelibrary.wiley.com/doi/10.14814/phy2.14460
  35. Jan 2020
  36. elifesciences.org elifesciences.org
    Extracellular Pgk1 enhances neurite outgrowth of motoneurons through Nogo66/NgR-independent targeting of NogoA
    1
    1. scibot 13 Jan 2020
      RRID:AB_330222

      DOI: 10.7554/eLife.49175

      Resource: (Cell Signaling Technology Cat# 2602, RRID:AB_330222)

      Curator: @Naa003

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      RRID:AB_330222 RRIDCUR:Validated
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    elifesciences.org/articles/49175
  37. www.sciencedirect.com www.sciencedirect.com
    PAK4 Kinase Activity Plays a Crucial Role in the Podosome Ring of Myeloid Cells
    1
    1. scibot 13 Jan 2020
      RRID:AB_330222

      DOI: 10.1016/j.celrep.2019.11.016

      Resource: (Cell Signaling Technology Cat# 2602, RRID:AB_330222)

      Curator: @ethanbadger

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      RRID:AB_330222 RRIDCUR:Validated
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    sciencedirect.com/science/article/pii/S2211124719314871
  38. www.jneurosci.org www.jneurosci.org
    Conditional Deletion of CC2D1A Reduces Hippocampal Synaptic Plasticity and Impairs Cognitive Function through Rac1 Hyperactivation
    1
    1. scibot 13 Jan 2020
      RRID:AB_330222

      DOI: 10.1523/JNEUROSCI.2395-18.2019

      Resource: (Cell Signaling Technology Cat# 2602, RRID:AB_330222)

      Curator: @Naa003

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      RRID:AB_330222 RRIDCUR:Validated
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    jneurosci.org/content/39/25/4959
  39. Nov 2018
  40. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Systematic Functional Annotation of Somatic Mutations in Cancer
    1
    1. scibot 05 Nov 2018
      RRID:AB_330222

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      (Cell Signaling Technology Cat# 2602, RRID:AB_330222)

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    ncbi.nlm.nih.gov/pmc/articles/PMC5926201/
  41. 52.53.155.43 52.53.155.43
    A dual role for Integrin α6β4 in modulating hereditary neuropathy with liability to pressure palsies
    1
    1. scibot 05 Nov 2018
      RRID:AB_330222

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      (Cell Signaling Technology Cat# 2602, RRID:AB_330222)

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    52.53.155.43/0bf5a35474616f8cd124d354ba59ef8784f885ac/A_dual_role_for_Integrin_64_in_modulat-html.html