30 Matching Annotations
  1. Jan 2026
  2. www.science.org www.science.org
    Synergistic intragenic epigenetic deregulation by IDH2 and SRSF2 mutations causes mis-splicing of key transcriptional regulators
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    science.org/doi/10.1126/sciadv.adu8292
  3. Jun 2025
  4. www.sciencedirect.com www.sciencedirect.com
    Dynamic decoding of VEGF signaling and coordinated control of multiple phenotypes by the Src-TEM4-YAP pathway
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    sciencedirect.com/science/article/pii/S2405471225001541
  5. Mar 2025
  6. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    The STRIPAK complex is required for radial sorting and laminin receptor expression in Schwann cells
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    pmc.ncbi.nlm.nih.gov/articles/PMC12035956/
  7. Feb 2025
  8. www.sciencedirect.com www.sciencedirect.com
    N-cadherin-triggered myosin II inactivation provides tumor cells with a mechanical cell competition advantage and chemotherapy resistance
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    sciencedirect.com/science/article/pii/S1534580725000619
  9. Dec 2024
  10. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Modelling quiescence exit of neural stem cells reveals a FOXG1-FOXO6 axis
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    pmc.ncbi.nlm.nih.gov/articles/PMC11625887/
  11. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    MET receptor tyrosine kinase promotes the generation of functional synapses in adult cortical circuits
    1
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    pmc.ncbi.nlm.nih.gov/articles/PMC11624886/
  12. Sep 2024
  13. www.sciencedirect.com www.sciencedirect.com
    IGFBP7 is upregulated in islets from T2D donors and reduces insulin secretion
    1
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    sciencedirect.com/science/article/pii/S2589004224019928
  14. Aug 2024
  15. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Fam49b dampens TCR signal strength to regulate survival of positively selected thymocytes and peripheral T cells
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC11333044/
  16. Jul 2024
  17. 52.53.155.43 52.53.155.43
    A dual role for Integrin α6β4 in modulating hereditary neuropathy with liability to pressure palsies
    1
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    52.53.155.43/0bf5a35474616f8cd124d354ba59ef8784f885ac/A_dual_role_for_Integrin_64_in_modulat-html.html
  18. Feb 2024
  19. www.science.org www.science.org
    RHOAL57V drives the development of diffuse gastric cancer through IGF1R-PAK1-YAP1 signaling
    1
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    science.org/doi/10.1126/scisignal.adg5289
  20. Jan 2024
  21. www.science.org www.science.org
    RHOAL57V drives the development of diffuse gastric cancer through IGF1R-PAK1-YAP1 signaling
    1
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    science.org/doi/10.1126/scisignal.adg5289
  22. Nov 2023
  23. www.sciencedirect.com www.sciencedirect.com
    PAK1-dependent mechanotransduction enables myofibroblast nuclear adaptation and chromatin organization during fibrosis
    1
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    sciencedirect.com/science/article/pii/S2211124723014262
  24. Aug 2023
  25. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The Evaluation of Rac1 Signaling as a Potential Therapeutic Target of Alzheimer’s Disease
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC10418761/
  26. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    PAK1 contributes to cerebral ischemia/reperfusion injury by regulating the blood-brain barrier integrity
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC10387573/
  27. Jun 2022
  28. www.nature.com www.nature.com
    Phosphoproteomic of the acetylcholine pathway enables discovery of the PKC-β-PIX-Rac1-PAK cascade as a stimulatory signal for aversive learning
    1
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    nature.com/articles/s41380-022-01643-2
  29. Apr 2022
  30. www.sciencedirect.com www.sciencedirect.com
    Lyso-PAF, a biologically inactive phospholipid, contributes to RAF1 activation
    1
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    sciencedirect.com/science/article/pii/S1097276522002647
  31. www.sciencedirect.com www.sciencedirect.com
    Structure-based design of CDC42 effector interaction inhibitors for the treatment of cancer
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    sciencedirect.com/science/article/pii/S221112472200393X
  32. Sep 2021
  33. www.sciencedirect.com www.sciencedirect.com
    Optimizing metastatic-cascade-dependent Rac1 targeting in breast cancer: Guidance using optical window intravital FRET imaging
    1
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    sciencedirect.com/science/article/pii/S2211124721011360
  34. journals.plos.org journals.plos.org
    A kinase-independent function of PAK is crucial for pathogen-mediated actin remodelling
    1
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    journals.plos.org/plospathogens/article
  35. Jul 2021
  36. mbio.asm.org mbio.asm.org
    Pathogenic Escherichia coli Hijacks GTPase-Activated p21-Activated Kinase for Actin Pedestal Formation
    1
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    mbio.asm.org/content/10/4/e01876-19
  37. Apr 2021
  38. www.jneurosci.org www.jneurosci.org
    PAK1 positively regulates oligodendrocyte morphology and myelination.
    1
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    jneurosci.org/content/41/9/1864
  39. Mar 2021
  40. www.sciencedirect.com www.sciencedirect.com
    Endothelin-1 drives invadopodia and interaction with mesothelial cells through ILK
    1
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    sciencedirect.com/science/article/pii/S2211124721001145
  41. Dec 2020
  42. physoc.onlinelibrary.wiley.com physoc.onlinelibrary.wiley.com
    Insulin‐stimulated glucose uptake partly relies on p21‐activated kinase 2 (PAK2), but not PAK1, in mouse skeletal muscle
    1
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    physoc.onlinelibrary.wiley.com/doi/10.1113/JP280294
  43. Sep 2020
  44. www.sciencedirect.com www.sciencedirect.com
    The Protein Arginine Methyltransferase PRMT8 and Substrate G3BP1 Control Rac1-PAK1 Signaling and Actin Cytoskeleton for Dendritic Spine Maturation
    1
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    sciencedirect.com/science/article/pii/S2211124720307245
  45. physoc.onlinelibrary.wiley.com physoc.onlinelibrary.wiley.com
    The p21‐activated kinase 2 (PAK2), but not PAK1, regulates contraction‐stimulated skeletal muscle glucose transport
    1
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    physoc.onlinelibrary.wiley.com/doi/10.14814/phy2.14460
  46. Jan 2020
  47. elifesciences.org elifesciences.org
    Extracellular Pgk1 enhances neurite outgrowth of motoneurons through Nogo66/NgR-independent targeting of NogoA
    1
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    elifesciences.org/articles/49175
  48. www.sciencedirect.com www.sciencedirect.com
    PAK4 Kinase Activity Plays a Crucial Role in the Podosome Ring of Myeloid Cells
    1
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    sciencedirect.com/science/article/pii/S2211124719314871
  49. www.jneurosci.org www.jneurosci.org
    Conditional Deletion of CC2D1A Reduces Hippocampal Synaptic Plasticity and Impairs Cognitive Function through Rac1 Hyperactivation
    1
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    jneurosci.org/content/39/25/4959
  50. Nov 2018
  51. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Systematic Functional Annotation of Somatic Mutations in Cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC5926201/
  52. 52.53.155.43 52.53.155.43
    A dual role for Integrin α6β4 in modulating hereditary neuropathy with liability to pressure palsies
    1
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    52.53.155.43/0bf5a35474616f8cd124d354ba59ef8784f885ac/A_dual_role_for_Integrin_64_in_modulat-html.html