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Integrin-linked kinase promotes hepatic fat accumulation via F-actin stabilization-dependent CD36 plasma membrane localization

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Jun 2026
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AMPK-mediated prevention of vascular dysfunction with metformin: Experimental and population-based evidence

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  DOI: 10.1111/bph.70533
  
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May 2026
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High intensity 40 Hz flicker improves amyloid pathology and cognition with autophagy in 3xTg mice

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The role of ATP synthase subunit e (ATP5I) in mediating the metabolic and antiproliferative effects of metformin in cancer cells

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  DOI: 10.7554/eLife.102680
  
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Glyceraldehyde-induced metabolic defects in cortical astrocytes: implication for Alzheimer's disease pathogenesis and therapy

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Mar 2026
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1-s2.0-S2589004226006206-main-html.html

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lara-castillo-et-al-2026-exercise-beneficially-reshapes-fasted-rat-skeletal-muscle-involving-the-combined-action-of-html.html

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Pyruvate-supported flux through medium-chain ketothiolase promotes mitochondrial lipid tolerance in cardiac and skeletal muscles

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pmc.ncbi.nlm.nih.gov/articles/PMC10330230/
Jan 2026
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Effect of tofogliflozin on skeletal muscle mitochondrial function in male diabetic mice with muscle atrophy

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pmc.ncbi.nlm.nih.gov/articles/PMC12852949/
Oct 2025
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C1orf116 inhibits acquired resistance to EGFR inhibitors in EGFR mutant lung adenocarcinoma by suppressing the ATM/ATR pathways

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pmc.ncbi.nlm.nih.gov/articles/PMC12541872/
Aug 2025
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PKD and scaffold NHERF1 mediate hypoxia-induced gene expression in 3T3-L1 adipocytes

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sciencedirect.com/org/science/article/pii/S1479681325000226
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Effect of 8-Methyl Nonanoic Acid, a Degradation By-Product of Dihydrocapsaicin, on Energy and Glucose Homeostasis in Diet-Induced Obese Mice

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jme-JME-25-0011-html.html

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Effect of 8-Methyl Nonanoic Acid, a Degradation By-Product of Dihydrocapsaicin, on Energy and Glucose Homeostasis in Diet-Induced Obese Mice

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pmc.ncbi.nlm.nih.gov/articles/PMC12358132/
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Lysosomal TPC2 channel as a new target of chlorpromazine and Clomipramine to induce protective autophagy in L-BMAA-induced neurodegeneration

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Jul 2025
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Lactoferrin attenuates renal fibrosis and uremic sarcopenia in a mouse model of adenine-induced chronic kidney disease

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The impact of neuregulin 4 on metabolic dysregulation in lipodystrophy

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pmc.ncbi.nlm.nih.gov/articles/PMC12236340/
Jun 2025
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Cold-inducible GOT1 activates the malate-aspartate shuttle in brown adipose tissue to support fuel preference for fatty acids

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Insulin- and exercise-induced phosphoproteomics of human skeletal muscle identify REPS1 as a regulator of muscle glucose uptake

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cell.com/cell-reports-medicine/fulltext/S2666-3791(25)00236-8
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EZH2 loss during metabolic stress drives restoration of MHC class I machinery in melanoma

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CD47-blocking antibody confers metabolic benefits against obesity

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An integrated proteomics approach identifies phosphorylation sites on viral and host proteins that regulate West Nile virus infection

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Dietary timing enhances exercise by modulating fat-muscle crosstalk via adipocyte AMPKα2 signaling

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Feb 2025
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Cellular deconstruction of the human skeletal muscle microenvironment identifies an exercise-induced histaminergic crosstalk

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Jan 2025
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The protective effects of liraglutide in reducing lipid droplets accumulation and myocardial fibrosis in diabetic cardiomyopathy

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pmc.ncbi.nlm.nih.gov/articles/PMC11711727/
Jun 2024
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Nesfatin-1 and nesfatin-1-like peptide attenuate hepatocyte lipid accumulation and nucleobindin-1 disruption modulates lipid metabolic pathways

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Apr 2024
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HDAC10 inhibition represses melanoma cell growth and BRAF inhibitor resistance via upregulating SPARC expression

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25-Hydroxycholesterol regulates lysosome AMP kinase activation and metabolic reprogramming to educate immunosuppressive macrophages

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AMPK activation modulates IL-36-induced inflammatory responses by regulating IκBζ expression in the skin

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Feb 2024
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Trans-omic analysis reveals opposite metabolic dysregulation between feeding and fasting in liver associated with obesity

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l-Methionine potentiates anticancer activity of Sorafenib by epigenetically altering DUSP3/ERK pathway in hepatocellular carcinoma

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Proline restores mitochondrial function and reverses aging hallmarks in senescent cells

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HDAC10 blockade upregulates SPARC expression thereby repressing melanoma cell growth and BRAF inhibitor resistance

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biorxiv.org/content/10.1101/2023.12.05.570182v1
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CD73-dependent generation of extracellular adenosine by vascular endothelial cells modulates de novo lipogenesis in adipose tissue

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ncbi.nlm.nih.gov/pmc/articles/PMC10803534/
Oct 2023
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Blocking AMPKαS496 phosphorylation improves mitochondrial dynamics and hyperglycemia in aging and obesity

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Sex Differences in the Skeletal Muscle Response to a High Fat, High Sucrose Diet in Rats

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Myotube growth is associated with cancer-like metabolic reprogramming and is limited by phosphoglycerate dehydrogenase

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sciencedirect.com/science/article/pii/S0014482723003713
Aug 2023
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The mitochondrial succinate dehydrogenase complex controls the STAT3-IL-10 pathway in inflammatory macrophages

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ncbi.nlm.nih.gov/pmc/articles/PMC10416071/
Jul 2023
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Bexarotene improves motor function after spinal cord injury in mice

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ncbi.nlm.nih.gov/pmc/articles/PMC10358692/
May 2023
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A genetic variant of fatty acid amide hydrolase (FAAH) exacerbates hormone-mediated orexigenic feeding in mice

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  DOI: 10.7554/eLife.81919
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10159625/
Apr 2023
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Live-cell imaging identifies cAMP microdomains regulating β-adrenoceptor-subtype-specific lipolytic responses in human white adipocytes

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Pyruvate-supported flux through medium-chain ketothiolase promotes mitochondrial lipid tolerance in cardiac and skeletal muscles

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  DOI: 10.1016/j.cmet.2023.03.016
  
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Mar 2023
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Exercise-acclimated microbiota improves skeletal muscle metabolism via circulating bile acid deconjugation

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ncbi.nlm.nih.gov/pmc/articles/PMC10005909/
Feb 2023
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Metabolic stress-induced human beta-cell death is mediated by increased intracellular levels of adenosine

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Inhibition of phosphodiesterase 5A by tadalafil improves SIRT1 expression and activity in insulin-resistant podocytes

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Jan 2023
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Perturbation of placental protein glycosylation by endoplasmic reticulum stress promotes maladaptation of maternal hepatic glucose metabolism

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ncbi.nlm.nih.gov/pmc/articles/PMC9843443/
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Fluorinated triphenylphosphonium analogs improve cell selectivity and in vivo detection of mito-metformin

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Skeletal muscle contraction kinetics and AMPK responses are modulated by the adenine nucleotide degrading enzyme AMPD1

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Nov 2022
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Liver autophagy-induced valine and leucine in plasma reflect the metabolic effect of sodium glucose co-transporter 2 inhibitor dapagliflozin

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SLC38A2 provides proline and alanine to regulate postnatal bone mass accrual in mice

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Simultaneous SGLT2 inhibition and caloric restriction improves insulin resistance and kidney function in OLETF rats

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sciencedirect.com/science/article/pii/S0303720722002593
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Rates of protein synthesis are maintained in brain but reduced in skeletal muscle during dietary sulfur amino acid restriction

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ncbi.nlm.nih.gov/pmc/articles/PMC9450999/
Jul 2022
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Extracellular Nicotinamide Phosphoribosyltransferase Is a Component of the Senescence-Associated Secretory Phenotype

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Pathological mitophagy disrupts mitochondrial homeostasis in Leber’s hereditary optic neuropathy

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sciencedirect.com/science/article/pii/S2211124722009305
Apr 2022
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A negative feedback loop of TOR signaling balances growth and stress-response trade-offs in plants

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Mar 2022
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BPS Publications

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Stress-induced autonomic dysregulation of mitochondrial function in the rat urothelium

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onlinelibrary.wiley.com/doi/10.1002/nau.23876
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Undercarboxylated Osteocalcin Improves Insulin-Stimulated Glucose Uptake in Muscles of Corticosterone-Treated Mice

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asbmr.onlinelibrary.wiley.com/doi/10.1002/jbmr.3731
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The anti-diabetic drug metformin regulates voltage-gated sodium channel NaV1.7 via the ubiquitin-ligase NEDD4-2

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eneuro.org/content/9/2/ENEURO.0409-21.2022
Feb 2022
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Probiotics counteract hepatic steatosis caused by ketogenic diet and upregulate AMPK signaling in a model of infantile epilepsy

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Dec 2021
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BPS Publications

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Anemic Hypoxemia Reduces Myoblast Proliferation and Muscle Growth in Late Gestation Fetal Sheep

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journals.physiology.org/doi/abs/10.1152/ajpregu.00342.2020
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Salbutamol increases leg glucose uptake and metabolic rate but not muscle glycogen resynthesis in recovery from exercise

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academic.oup.com/jcem/advance-article/doi/10.1210/clinem/dgab752/6403262
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ajpregu.00342.2020-html.html

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Acetyl-CoA derived from hepatic mitochondrial fatty acid β-oxidation aggravates inflammation by enhancing p65 acetylation

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ncbi.nlm.nih.gov/pmc/articles/PMC8551082/
Sep 2021
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Uteroplacental nutrient flux and evidence for metabolic reprogramming during sustained hypoxemia

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physoc.onlinelibrary.wiley.com/doi/10.14814/phy2.15033
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C1q/tumor necrosis factor-related protein-3 improves microvascular endothelial function in diabetes through the AMPK/eNOS/NO· signaling pathway

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sciencedirect.com/science/article/pii/S0006295221003610
Aug 2021
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Crosstalk of hypothalamic chemerin, histamine, and AMPK in diet-and olanzapine-induced obesity in rats

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GDF15 mediates the metabolic effects of PPARβ/δ by activating AMPK

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AMPK activation reverts mouse epiblast stem cells to naive state

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Impairment of Angiogenesis by Fatty Acid Synthase Inhibition Involves mTOR Malonylation

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Protective effect of exercise training against the progression of Alzheimer’s disease in 3xTg-AD mice

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Glutamine Metabolism Regulates Proliferation and Lineage Allocation in Skeletal Stem Cells

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BPS Publications

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  phospho‐AMP‐activated protein kinase (AMPK; Thr172) rabbit mAb
  
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The autophagy protein Becn1 improves insulin sensitivity by promoting adiponectin secretion via exocyst binding

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Functional Interplay between Histone H2B ADP-Ribosylation and Phosphorylation Controls Adipogenesis

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Acetyl-CoA Derived from Hepatic Peroxisomal β-Oxidation Inhibits Autophagy and Promotes Steatosis via mTORC1 Activation

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Placental superoxide dismutase 3 mediates benefits of maternal exercise on offspring health

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Profiling of microRNA targets using activity-based protein profiling: linking enzyme activity to microRNA-185 function

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Physiological hypoxia restrains the senescence-associated secretory phenotype via AMPK-mediated mTOR suppression

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Yeast Nuak1 phosphorylates histone H3 threonine 11 in low glucose stress by the cooperation of AMPK and CK2 signaling

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North American Wild Rice Attenuated Hyperglycemia in High Fat-Induced Obese Mice: Involvement of AMP-Activated Protein Kinase

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Reporting animal research: Explanation and elaboration for the ARRIVE guidelines 2.0

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Mitochondrial dysfunction in skeletal muscle of fukutin deficient mice is resistant to exercise‐ and AICAR‐induced rescue

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Defective Mitochondrial Pyruvate Flux Affects Cell Bioenergetics in Alzheimer’s Disease-Related Models

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The p21‐activated kinase 2 (PAK2), but not PAK1, regulates contraction‐stimulated skeletal muscle glucose transport

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YAP1 regulates chondrogenic differentiation of ATDC5 promoted by temporary TNF-α stimulation through AMPK signaling pathway

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North American Wild Rice Attenuated Hyperglycemia in High Fat-Induced Obese Mice: Involvement of AMP-Activated Protein Kinase

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Genetic loss of AMPK-glycogen binding destabilizes AMPK and disrupts metabolism

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  phospho-AMPK Thr172
  
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Metformin Improves Mitochondrial Respiratory Activity through Activation of AMPK

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SIRT6 Promotes Hepatic Beta-Oxidation via Activation of PPARα

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Metformin Ameliorates Lipotoxic β-Cell Dysfunction through a Concentration-Dependent Dual Mechanism of Action

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  DOI: 10.4093/dmj.2018.0179
  
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microRNA‐141 is associated with hepatic steatosis by downregulating the sirtuin1/AMP‐activated protein kinase pathway in hepatocytes

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Activation of Mevalonate Pathway via LKB1 Is Essential for Stability of Treg Cells

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Untitled document

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Suppressing Mitochondrial Respiration Is Critical for Hypoxia Tolerance in the Fetal Growth Plate

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Glutamine Metabolism Regulates Proliferation and Lineage Allocation in Skeletal Stem Cells

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Genetic Removal of eIF2α Kinase PERK in Mice Enables Hippocampal L‐LTP Independent of mTORC1 Activity

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Short-Term Mitochondrial Permeability Transition Pore Opening Modulates Histone Lysine Methylation at the Early Phase of Somatic Cell Reprogramming

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Quiescent Endothelial Cells Upregulate Fatty Acid β-Oxidation for Vasculoprotection via Redox Homeostasis

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Acetyl-CoA Carboxylase 1-Dependent Protein Acetylation Controls Breast Cancer Metastasis and Recurrence

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Antagonizing peroxisome proliferator‐activated receptor γ facilitates M1‐to‐M2 shift of microglia by enhancing autophagy via the LKB1–AMPK signaling pathway

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Combination therapy of lovastatin and AMP‐activated protein kinase activator improves mitochondrial and peroxisomal functions and clinical disease in experimental autoimmune encephalomyelitis model

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Autophagy impairment by caspase‐1‐dependent inflammation mediates memory loss in response to β‐Amyloid peptide accumulation

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Pimozide reduces toxic forms of tau in TauC3 mice via AMPK‐mediated autophagy

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CTRP3 is a novel biomarker for diabetic retinopathy and inhibits HGHL-induced VCAM-1 expression in an AMPK-dependent manner

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PPARβ Is Essential for Maintaining Normal Levels of PGC-1α and Mitochondria and for the Increase in Muscle Mitochondria Induced by Exercise

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Mechanisms of Paradoxical Activation of AMPK by the Kinase Inhibitors SU6656 and Sorafenib

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