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Effect of tofogliflozin on skeletal muscle mitochondrial function in male diabetic mice with muscle atrophy

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1. scibot 31 Jan 2026
  
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  DOI: 10.1210/jendso/bvaf171
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12852949/
Oct 2025
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C1orf116 inhibits acquired resistance to EGFR inhibitors in EGFR mutant lung adenocarcinoma by suppressing the ATM/ATR pathways

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1. scibot 25 Oct 2025
  
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  DOI: 10.21037/tlcr-2025-265
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12541872/
Aug 2025
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PKD and scaffold NHERF1 mediate hypoxia-induced gene expression in 3T3-L1 adipocytes

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1. scibot 29 Aug 2025
  
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  DOI: 10.1530/JME-25-0011
  
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sciencedirect.com/org/science/article/pii/S1479681325000226
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Effect of 8-Methyl Nonanoic Acid, a Degradation By-Product of Dihydrocapsaicin, on Energy and Glucose Homeostasis in Diet-Induced Obese Mice

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1. scibot 20 Aug 2025
  
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  DOI: 10.2147/JEP.S536185
  
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tandfonline.com/doi/abs/10.2147/JEP.S536185
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jme-JME-25-0011-html.html

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1. scibot 20 Aug 2025
  
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  DOI: 10.1530/JME-25-0011
  
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52.53.155.43/25ff8971991199eba559b6c65cd9d78332cbc5b8/jme-JME-25-0011-html.html
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Effect of 8-Methyl Nonanoic Acid, a Degradation By-Product of Dihydrocapsaicin, on Energy and Glucose Homeostasis in Diet-Induced Obese Mice

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1. scibot 19 Aug 2025
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12358132/
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Lysosomal TPC2 channel as a new target of chlorpromazine and Clomipramine to induce protective autophagy in L-BMAA-induced neurodegeneration

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1. scibot 12 Aug 2025
  
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  DOI: 10.1016/j.bcp.2025.117219
  
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sciencedirect.com/science/article/pii/S0006295225004848
Jul 2025
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Lactoferrin attenuates renal fibrosis and uremic sarcopenia in a mouse model of adenine-induced chronic kidney disease

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1. scibot 29 Jul 2025
  
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  DOI: 10.1016/j.jnutbio.2025.110039
  
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sciencedirect.com/science/article/pii/S0955286325002025
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The impact of neuregulin 4 on metabolic dysregulation in lipodystrophy

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1. scibot 10 Jul 2025
  
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  DOI: 10.1210/endocr/bqaf112
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12236340/
Jun 2025
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Cold-inducible GOT1 activates the malate-aspartate shuttle in brown adipose tissue to support fuel preference for fatty acids

1
1. scibot 21 Jun 2025
  
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  DOI: 10.1016/j.celrep.2025.115888
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12294511/
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Insulin- and exercise-induced phosphoproteomics of human skeletal muscle identify REPS1 as a regulator of muscle glucose uptake

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1. scibot 12 Jun 2025
  
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  DOI: 10.1016/j.xcrm.2025.102163
  
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cell.com/cell-reports-medicine/fulltext/S2666-3791(25)00236-8
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EZH2 loss during metabolic stress drives restoration of MHC class I machinery in melanoma

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1. scibot 12 Jun 2025
  
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  DOI: 10.1016/j.isci.2025.112750
  
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sciencedirect.com/science/article/pii/S2589004225010119
May 2025
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CD47-blocking antibody confers metabolic benefits against obesity

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1. scibot 19 May 2025
  
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  DOI: 10.1016/j.xcrm.2025.102089
  
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cell.com/cell-reports-medicine/abstract/S2666-3791(25)00162-4
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An integrated proteomics approach identifies phosphorylation sites on viral and host proteins that regulate West Nile virus infection

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1. scibot 17 May 2025
  
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  DOI: 10.1016/j.celrep.2025.115728
  
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sciencedirect.com/science/article/pii/S2211124725004991
Mar 2025
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Dietary timing enhances exercise by modulating fat-muscle crosstalk via adipocyte AMPKα2 signaling

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1. scibot 20 Mar 2025
  
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  DOI: 10.1016/j.cmet.2025.02.007
  
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sciencedirect.com/science/article/pii/S1550413125000658
Feb 2025
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Cellular deconstruction of the human skeletal muscle microenvironment identifies an exercise-induced histaminergic crosstalk

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1. scibot 07 Feb 2025
  
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  DOI: 10.1016/j.cmet.2024.12.011
  
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sciencedirect.com/science/article/pii/S1550413124004935
Jan 2025
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The protective effects of liraglutide in reducing lipid droplets accumulation and myocardial fibrosis in diabetic cardiomyopathy

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1. scibot 15 Jan 2025
  
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  DOI: 10.1007/s00018-024-05558-9
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11711727/
Jun 2024
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Nesfatin-1 and nesfatin-1-like peptide attenuate hepatocyte lipid accumulation and nucleobindin-1 disruption modulates lipid metabolic pathways

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1. scibot 02 Jun 2024
  
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  DOI: 10.1038/s42003-024-06314-2
  
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nature.com/articles/s42003-024-06314-2
Apr 2024
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HDAC10 inhibition represses melanoma cell growth and BRAF inhibitor resistance via upregulating SPARC expression

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1. scibot 24 Apr 2024
  
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  DOI: 10.1093/narcan/zcae018
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11034028/
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25-Hydroxycholesterol regulates lysosome AMP kinase activation and metabolic reprogramming to educate immunosuppressive macrophages

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1. scibot 19 Apr 2024
  
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  DOI: 10.1016/j.immuni.2024.03.021
  
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sciencedirect.com/science/article/pii/S1074761324001420
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AMPK activation modulates IL-36-induced inflammatory responses by regulating IκBζ expression in the skin

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1. scibot 11 Apr 2024
  
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  DOI: 10.1111/bph.16354
  
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2. scibot 11 Apr 2024
  
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  DOI: 10.1111/bph.16354
  
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bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.16354
Feb 2024
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Trans-omic analysis reveals opposite metabolic dysregulation between feeding and fasting in liver associated with obesity

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1. scibot 27 Feb 2024
  
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l-Methionine potentiates anticancer activity of Sorafenib by epigenetically altering DUSP3/ERK pathway in hepatocellular carcinoma

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1. scibot 22 Feb 2024
  
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  DOI: 10.1002/jbt.23663
  
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onlinelibrary.wiley.com/doi/10.1002/jbt.23663
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Proline restores mitochondrial function and reverses aging hallmarks in senescent cells

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1. scibot 14 Feb 2024
  
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  DOI: 10.1016/j.celrep.2024.113738
  
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sciencedirect.com/science/article/pii/S2211124724000664
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HDAC10 blockade upregulates SPARC expression thereby repressing melanoma cell growth and BRAF inhibitor resistance

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1. scibot 09 Feb 2024
  
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  DOI: 10.1101/2023.12.05.570182
  
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2. scibot 09 Feb 2024
  
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  DOI: 10.1101/2023.12.05.570182
  
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  DOI: 10.1101/2023.12.05.570182
  
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biorxiv.org/content/10.1101/2023.12.05.570182v1
Jan 2024
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CD73-dependent generation of extracellular adenosine by vascular endothelial cells modulates de novo lipogenesis in adipose tissue

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1. scibot 26 Jan 2024
  
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  DOI: 10.3389/fimmu.2023.1308456
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10803534/
Oct 2023
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Blocking AMPKαS496 phosphorylation improves mitochondrial dynamics and hyperglycemia in aging and obesity

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1. scibot 28 Oct 2023
  
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  DOI: 10.1016/j.chembiol.2023.09.017
  
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sciencedirect.com/science/article/pii/S2451945623003367
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Sex Differences in the Skeletal Muscle Response to a High Fat, High Sucrose Diet in Rats

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1. scibot 27 Oct 2023
  
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  DOI: 10.3390/nu15204438
  
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mdpi.com/2072-6643/15/20/4438
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Myotube growth is associated with cancer-like metabolic reprogramming and is limited by phosphoglycerate dehydrogenase

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1. scibot 27 Oct 2023
  
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  DOI: 10.1016/j.yexcr.2023.113820
  
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sciencedirect.com/science/article/pii/S0014482723003713
Aug 2023
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The mitochondrial succinate dehydrogenase complex controls the STAT3-IL-10 pathway in inflammatory macrophages

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1. scibot 16 Aug 2023
  
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  DOI: 10.1016/j.isci.2023.107473
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10416071/
Jul 2023
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Bexarotene improves motor function after spinal cord injury in mice

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1. scibot 22 Jul 2023
  
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  DOI: 10.4103/1673-5374.373676
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10358692/
May 2023
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A genetic variant of fatty acid amide hydrolase (FAAH) exacerbates hormone-mediated orexigenic feeding in mice

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1. scibot 06 May 2023
  
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  DOI: 10.7554/eLife.81919
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10159625/
Apr 2023
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Live-cell imaging identifies cAMP microdomains regulating β-adrenoceptor-subtype-specific lipolytic responses in human white adipocytes

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1. scibot 26 Apr 2023
  
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  DOI: 10.1016/j.celrep.2023.112433
  
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sciencedirect.com/science/article/pii/S2211124723004448
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Pyruvate-supported flux through medium-chain ketothiolase promotes mitochondrial lipid tolerance in cardiac and skeletal muscles

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1. scibot 15 Apr 2023
  
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Exercise-acclimated microbiota improves skeletal muscle metabolism via circulating bile acid deconjugation

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Metabolic stress-induced human beta-cell death is mediated by increased intracellular levels of adenosine

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Inhibition of phosphodiesterase 5A by tadalafil improves SIRT1 expression and activity in insulin-resistant podocytes

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Perturbation of placental protein glycosylation by endoplasmic reticulum stress promotes maladaptation of maternal hepatic glucose metabolism

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Fluorinated triphenylphosphonium analogs improve cell selectivity and in vivo detection of mito-metformin

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Skeletal muscle contraction kinetics and AMPK responses are modulated by the adenine nucleotide degrading enzyme AMPD1

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Liver autophagy-induced valine and leucine in plasma reflect the metabolic effect of sodium glucose co-transporter 2 inhibitor dapagliflozin

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SLC38A2 provides proline and alanine to regulate postnatal bone mass accrual in mice

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Simultaneous SGLT2 inhibition and caloric restriction improves insulin resistance and kidney function in OLETF rats

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Rates of protein synthesis are maintained in brain but reduced in skeletal muscle during dietary sulfur amino acid restriction

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Extracellular Nicotinamide Phosphoribosyltransferase Is a Component of the Senescence-Associated Secretory Phenotype

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Pathological mitophagy disrupts mitochondrial homeostasis in Leber’s hereditary optic neuropathy

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A negative feedback loop of TOR signaling balances growth and stress-response trade-offs in plants

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BPS Publications

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Stress-induced autonomic dysregulation of mitochondrial function in the rat urothelium

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Undercarboxylated Osteocalcin Improves Insulin-Stimulated Glucose Uptake in Muscles of Corticosterone-Treated Mice

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The anti-diabetic drug metformin regulates voltage-gated sodium channel NaV1.7 via the ubiquitin-ligase NEDD4-2

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Probiotics counteract hepatic steatosis caused by ketogenic diet and upregulate AMPK signaling in a model of infantile epilepsy

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Anemic Hypoxemia Reduces Myoblast Proliferation and Muscle Growth in Late Gestation Fetal Sheep

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Salbutamol increases leg glucose uptake and metabolic rate but not muscle glycogen resynthesis in recovery from exercise

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ajpregu.00342.2020-html.html

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Acetyl-CoA derived from hepatic mitochondrial fatty acid β-oxidation aggravates inflammation by enhancing p65 acetylation

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Uteroplacental nutrient flux and evidence for metabolic reprogramming during sustained hypoxemia

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C1q/tumor necrosis factor-related protein-3 improves microvascular endothelial function in diabetes through the AMPK/eNOS/NO· signaling pathway

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Crosstalk of hypothalamic chemerin, histamine, and AMPK in diet-and olanzapine-induced obesity in rats

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GDF15 mediates the metabolic effects of PPARβ/δ by activating AMPK

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AMPK activation reverts mouse epiblast stem cells to naive state

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Impairment of Angiogenesis by Fatty Acid Synthase Inhibition Involves mTOR Malonylation

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Protective effect of exercise training against the progression of Alzheimer’s disease in 3xTg-AD mice

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Glutamine Metabolism Regulates Proliferation and Lineage Allocation in Skeletal Stem Cells

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BPS Publications

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  phospho‐AMP‐activated protein kinase (AMPK; Thr172) rabbit mAb
  
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The autophagy protein Becn1 improves insulin sensitivity by promoting adiponectin secretion via exocyst binding

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Functional Interplay between Histone H2B ADP-Ribosylation and Phosphorylation Controls Adipogenesis

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Acetyl-CoA Derived from Hepatic Peroxisomal β-Oxidation Inhibits Autophagy and Promotes Steatosis via mTORC1 Activation

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Placental superoxide dismutase 3 mediates benefits of maternal exercise on offspring health

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Profiling of microRNA targets using activity-based protein profiling: linking enzyme activity to microRNA-185 function

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Physiological hypoxia restrains the senescence-associated secretory phenotype via AMPK-mediated mTOR suppression

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Yeast Nuak1 phosphorylates histone H3 threonine 11 in low glucose stress by the cooperation of AMPK and CK2 signaling

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North American Wild Rice Attenuated Hyperglycemia in High Fat-Induced Obese Mice: Involvement of AMP-Activated Protein Kinase

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Reporting animal research: Explanation and elaboration for the ARRIVE guidelines 2.0

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Mitochondrial dysfunction in skeletal muscle of fukutin deficient mice is resistant to exercise‐ and AICAR‐induced rescue

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Defective Mitochondrial Pyruvate Flux Affects Cell Bioenergetics in Alzheimer’s Disease-Related Models

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The p21‐activated kinase 2 (PAK2), but not PAK1, regulates contraction‐stimulated skeletal muscle glucose transport

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YAP1 regulates chondrogenic differentiation of ATDC5 promoted by temporary TNF-α stimulation through AMPK signaling pathway

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North American Wild Rice Attenuated Hyperglycemia in High Fat-Induced Obese Mice: Involvement of AMP-Activated Protein Kinase

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Genetic loss of AMPK-glycogen binding destabilizes AMPK and disrupts metabolism

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  phospho-AMPK Thr172
  
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Metformin Improves Mitochondrial Respiratory Activity through Activation of AMPK

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SIRT6 Promotes Hepatic Beta-Oxidation via Activation of PPARα

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Metformin Ameliorates Lipotoxic β-Cell Dysfunction through a Concentration-Dependent Dual Mechanism of Action

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microRNA‐141 is associated with hepatic steatosis by downregulating the sirtuin1/AMP‐activated protein kinase pathway in hepatocytes

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Activation of Mevalonate Pathway via LKB1 Is Essential for Stability of Treg Cells

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Suppressing Mitochondrial Respiration Is Critical for Hypoxia Tolerance in the Fetal Growth Plate

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Glutamine Metabolism Regulates Proliferation and Lineage Allocation in Skeletal Stem Cells

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Genetic Removal of eIF2α Kinase PERK in Mice Enables Hippocampal L‐LTP Independent of mTORC1 Activity

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Short-Term Mitochondrial Permeability Transition Pore Opening Modulates Histone Lysine Methylation at the Early Phase of Somatic Cell Reprogramming

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Quiescent Endothelial Cells Upregulate Fatty Acid β-Oxidation for Vasculoprotection via Redox Homeostasis

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Acetyl-CoA Carboxylase 1-Dependent Protein Acetylation Controls Breast Cancer Metastasis and Recurrence

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sciencedirect.com/science/article/pii/S1550413117305703
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Antagonizing peroxisome proliferator‐activated receptor γ facilitates M1‐to‐M2 shift of microglia by enhancing autophagy via the LKB1–AMPK signaling pathway

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onlinelibrary.wiley.com/doi/full/10.1111/acel.12774
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jneurosci.org/content/38/4/1015
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Combination therapy of lovastatin and AMP‐activated protein kinase activator improves mitochondrial and peroxisomal functions and clinical disease in experimental autoimmune encephalomyelitis model

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onlinelibrary.wiley.com/doi/10.1111/imm.12893/full
Nov 2017
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Autophagy impairment by caspase‐1‐dependent inflammation mediates memory loss in response to β‐Amyloid peptide accumulation

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1. scibot 08 Nov 2017
  
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onlinelibrary.wiley.com/doi/10.1002/jnr.24130/full
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Pimozide reduces toxic forms of tau in TauC3 mice via AMPK‐mediated autophagy

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onlinelibrary.wiley.com/doi/10.1111/jnc.14109/full
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CTRP3 is a novel biomarker for diabetic retinopathy and inhibits HGHL-induced VCAM-1 expression in an AMPK-dependent manner

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PPARβ Is Essential for Maintaining Normal Levels of PGC-1α and Mitochondria and for the Increase in Muscle Mitochondria Induced by Exercise

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Mechanisms of Paradoxical Activation of AMPK by the Kinase Inhibitors SU6656 and Sorafenib

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1. scibot 08 Nov 2017
  
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sciencedirect.com/science/article/pii/S2451945617301848

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