44 Matching Annotations
  1. Nov 2024
  2. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Deciphering the composition and key driver genes of breast invasive micropapillary carcinoma by multi-omics analysis
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    1. scibot 14 Nov 2024
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      DOI: 10.1016/j.isci.2024.111178

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    pmc.ncbi.nlm.nih.gov/articles/PMC11549989/
  3. Aug 2024
  4. jbiomedsci.biomedcentral.com jbiomedsci.biomedcentral.com
    Proteasome inhibitors restore the STAT1 pathway and enhance the expression of MHC class I on human colon cancer cells
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    1. scibot 02 Aug 2024
      3771

      DOI: 10.1186/s12929-021-00769-9

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  5. www.mdpi.com www.mdpi.com
    A Novel Monoclonal Antibody Targeting Cancer-Specific Plectin Has Potent Antitumor Activity in Ovarian Cancer
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    1. scibot 02 Aug 2024
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      DOI: 10.3390/cells10092218

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    mdpi.com/2073-4409/10/9/2218/htm
  6. Jul 2024
  7. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Influenza A virus infection activates STAT3 to enhance SREBP2 expression, cholesterol biosynthesis, and virus replication
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    1. scibot 19 Jul 2024
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    ncbi.nlm.nih.gov/pmc/articles/PMC11301072/
  8. May 2024
  9. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Ruxolitinib improves the inflammatory microenvironment, restores glutamate homeostasis, and promotes functional recovery after spinal cord injury
    1
    1. scibot 15 May 2024
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      DOI: 10.4103/NRR.NRR-D-23-01863

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    ncbi.nlm.nih.gov/pmc/articles/PMC11090442/
  10. www.sciencedirect.com www.sciencedirect.com
    Active substances and molecular mechanisms of Astragali Radix and Angelicae Sinensis Radix against idiopathic pulmonary fibrosis effects by network pharmacology and in vitro experiments
    1
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      DOI: 10.1016/j.cjac.2024.100397

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    sciencedirect.com/science/article/pii/S1872204024000422
  11. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    BPS Publications
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    1. scibot 02 May 2024
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      DOI: 10.1111/bph.16393

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  12. Apr 2024
  13. www.sciencedirect.com www.sciencedirect.com
    Cancer SLC6A6-mediated taurine uptake transactivates immune checkpoint genes and induces exhaustion in CD8+ T cells
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    1. scibot 02 Apr 2024
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    sciencedirect.com/science/article/pii/S0092867424003039
  14. Mar 2024
  15. www.sciencedirect.com www.sciencedirect.com
    Type I gamma phosphatidylinositol phosphate 5-kinase i5 controls cell sensitivity to interferon
    2
    1. scibot 06 Mar 2024
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      DOI: 10.1016/j.devcel.2024.02.005

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    2. scibot 06 Mar 2024
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    sciencedirect.com/science/article/pii/S1534580724000765
  16. Dec 2023
  17. www.sciencedirect.com www.sciencedirect.com
    Tissue factor binds to and inhibits interferon-α receptor 1 signaling
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    1. scibot 23 Dec 2023
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      DOI: 10.1016/j.immuni.2023.11.017

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    sciencedirect.com/science/article/pii/S1074761323004995
  18. Nov 2023
  19. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Tamoxifen for the treatment of myeloproliferative neoplasms: A Phase II clinical trial and exploratory analysis
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    1. scibot 30 Nov 2023
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      DOI: 10.1038/s41467-023-43175-5

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    ncbi.nlm.nih.gov/pmc/articles/PMC10673935/
  20. www.sciencedirect.com www.sciencedirect.com
    Exosomes derived from platelet-rich plasma promote diabetic wound healing via the JAK2/STAT3 pathway
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    1. scibot 04 Nov 2023
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      DOI: 10.1016/j.isci.2023.108236

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    sciencedirect.com/science/article/pii/S2589004223023131
  21. Oct 2023
  22. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    High NEK2 expression in myeloid progenitors suppresses T cell immunity in multiple myeloma
    1
    1. scibot 14 Oct 2023
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      DOI: 10.1016/j.xcrm.2023.101214

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    pmc.ncbi.nlm.nih.gov/articles/PMC10591052/
  23. Sep 2023
  24. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Crizotinib has Preclinical Efficacy in Philadelphia-negative Myeloproliferative Neoplasms
    1
    1. scibot 07 Sep 2023
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      DOI: 10.1158/1078-0432.CCR-22-1763

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  25. Aug 2023
  26. 52.53.155.43 52.53.155.43
    British J Pharmacology - 2023 - Han-html.html
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    1. scibot 16 Aug 2023
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      DOI: 10.1111/bph.16208

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    52.53.155.43/5e554e9cedd6e38ae632f7a8eb735fb3080af333/British J Pharmacology - 2023 - Han-html.html
  27. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Distinct Assemblies of Heterodimeric Cytokine Receptors Govern Stemness Programs in Leukemia
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    1. scibot 10 Aug 2023
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      DOI: 10.1158/2159-8290.CD-22-1396

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  28. Jul 2023
  29. www.sciencedirect.com www.sciencedirect.com
    mTOR inhibition reprograms cellular proteostasis by regulating eIF3D-mediated selective mRNA translation and promotes cell phenotype switching
    1
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      DOI: 10.1016/j.celrep.2023.112868

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    sciencedirect.com/science/article/pii/S2211124723008793
  30. Jun 2023
  31. www.sciencedirect.com www.sciencedirect.com
    New scaffolds for type II JAK2 inhibitors overcome the acquired G993A resistance mutation
    1
    1. scibot 08 Jun 2023
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      DOI: 10.1016/j.chembiol.2023.05.007

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    sciencedirect.com/science/article/pii/S2451945623001502
  32. May 2023
  33. www.sciencedirect.com www.sciencedirect.com
    Targeting of Annexin A1 in Tumor-associated Macrophages as a Therapeutic Strategy for Hepatocellular Carcinoma
    1
    1. scibot 20 May 2023
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      DOI: 10.1016/j.bcp.2023.115612

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    sciencedirect.com/science/article/pii/S0006295223002034
  34. journals.aai.org journals.aai.org
    cGAS Mediates Inflammation by Polarizing Macrophages to M1 Phenotype via the mTORC1 Pathway
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    1. scibot 13 May 2023
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      DOI: 10.4049/jimmunol.2200351

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    journals.aai.org/jimmunol/article/210/8/1098/263495/cGAS-Mediates-Inflammation-by-Polarizing
  35. www.sciencedirect.com www.sciencedirect.com
    Exercise-derived peptide protects against pathological cardiac remodeling
    1
    1. scibot 05 May 2023
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      DOI: 10.1016/j.ebiom.2022.104164

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    sciencedirect.com/science/article/pii/S2352396422003450
  36. Mar 2023
  37. 52.53.155.43 52.53.155.43
    943-html.html
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      DOI: 10.1158/1078-0432.ccr-22-1763

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    52.53.155.43/c8f103b982e67ed0e9f7f2acbda462e2c6f6fa27/943-html.html
  38. May 2022
  39. pubs.acs.org pubs.acs.org
    Simultaneous Delivery of Doxorubicin and Protease Inhibitor Derivative to Solid Tumors via Star-Shaped Polymer Nanomedicines Overcomes P-gp- and STAT3-Mediated Chemoresistance
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    1. scibot 24 May 2022
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      DOI: 10.1021/acs.biomac.2c00256

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    pubs.acs.org/doi/full/10.1021/acs.biomac.2c00256
  40. Apr 2022
  41. academic.oup.com academic.oup.com
    GH action in prostate cancer cells promotes proliferation limits apoptosis and regulates cancer-related gene expression
    1
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      DOI: 10.1210/endocr/bqac031

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    academic.oup.com/endo/article/163/5/bqac031/6564019
  42. www.nature.com www.nature.com
    Identifying a confused cell identity for esophageal squamous cell carcinoma
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      DOI: 10.1038/s41392-022-00946-8

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    nature.com/articles/s41392-022-00946-8
  43. Mar 2022
  44. journals.lww.com journals.lww.com
    Ruxolitinib attenuates secondary injury after traumatic spinal cord injury
    1
    1. scibot 10 Mar 2022
      RRID:AB_330403

      DOI: 10.4103/1673-5374.335165

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    journals.lww.com/nrronline/Fulltext/2022/17090/Ruxolitinib_attenuates_secondary_injury_after.35.aspx
  45. www.sciencedirect.com www.sciencedirect.com
    Abi1 mediates airway smooth muscle cell proliferation and airway remodeling via Jak2/STAT3 signaling
    1
    1. scibot 02 Mar 2022
      RRID:AB_33040

      DOI: 10.1016/j.isci.2022.103833

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      Curator comments: Phospho-Jak2 (Tyr1007/1008) Antibody Cell Signaling Technology Cat# 3771

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    sciencedirect.com/science/article/pii/S2589004222001031
  46. Nov 2021
  47. elifesciences.org elifesciences.org
    Mitochondrial respiration contributes to the interferon gamma response in antigen-presenting cells
    1
    1. scibot 24 Nov 2021
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      DOI: 10.7554/eLife.65109

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    elifesciences.org/articles/65109
  48. Oct 2021
  49. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Schlafen 11 expression in human acute leukemia cells with gain-of-function mutations in the interferon-JAK signaling pathway
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      DOI: 10.1016/j.isci.2021.103173

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    ncbi.nlm.nih.gov/pmc/articles/PMC8517841/
  50. Jun 2021
  51. www.hindawi.com www.hindawi.com
    Table 2 | Saussureae Radix Attenuates Neuroinflammation in LPS-Stimulated Mouse BV2 Microglia via HO-1/Nrf-2 Induction and Inflammatory Pathway Inhibition
    1
    1. scibot 29 Jun 2021
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      DOI: 10.1155/2021/6687089

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    hindawi.com/journals/mi/2021/6687089/tab2/
  52. May 2021
  53. www.sciencedirect.com www.sciencedirect.com
    An active marine halophenol derivative attenuates lipopolysaccharide-induced acute liver injury in mice by improving M2 macrophage-mediated therapy
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      DOI: 10.1016/j.intimp.2021.107676

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    sciencedirect.com/science/article/pii/S156757692100312X
  54. www.sciencedirect.com www.sciencedirect.com
    RhoA/Cdc42 signaling drives cytoplasmic maturation but not endomitosis in megakaryocytes
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      DOI: 10.1016/j.celrep.2021.109102

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    sciencedirect.com/science/article/pii/S2211124721004368
  55. Mar 2021
  56. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    BPS Publications
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      RRID:AB_330403

      DOI: 10.1111/bph.15357

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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.15357
  57. Jan 2021
  58. www.sciencedirect.com www.sciencedirect.com
    Critical role of Syk-dependent STAT1 activation in innate antiviral immunity
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      DOI: 10.1016/j.celrep.2020.108627

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    sciencedirect.com/science/article/pii/S2211124720316168
  59. Sep 2020
  60. www.sciencedirect.com www.sciencedirect.com
    Complex Autoinflammatory Syndrome Unveils Fundamental Principles of JAK1 Kinase Transcriptional and Biochemical Function
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      DOI: 10.1016/j.immuni.2020.07.006

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    sciencedirect.com/science/article/pii/S1074761320303137
  61. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    A chalcone derivative, 1m‐6, exhibits atheroprotective effects by increasing cholesterol efflux and reducing inflammation‐induced endothelial dysfunction
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      DOI: 10.1111/bph.15175

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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.15175
  62. www.sciencedirect.com www.sciencedirect.com
    Adipocyte Fatty Acid Transfer Supports Megakaryocyte Maturation
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      DOI: 10.1016/j.celrep.2020.107875

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    sciencedirect.com/science/article/pii/S2211124720308561
  63. www.sciencedirect.com www.sciencedirect.com
    The Natural Compound Notopterol Binds and Targets JAK2/3 to Ameliorate Inflammation and Arthritis
    1
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      DOI: 10.1016/j.celrep.2020.108158

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    sciencedirect.com/science/article/pii/S2211124720311475
  64. Jan 2020
  65. www.sciencedirect.com www.sciencedirect.com
    Deficiency in BDNF/TrkB Neurotrophic Activity Stimulates δ-Secretase by Upregulating C/EBPβ in Alzheimer’s Disease
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      DOI: 10.1016/j.celrep.2019.06.054

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    sciencedirect.com/science/article/pii/S2211124719308277
  66. www.sciencedirect.com www.sciencedirect.com
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    1. scibot 13 Jan 2020
      RRID:AB_330403

      DOI: 10.1016/j.celrep.2019.04.066

      Resource: (Cell Signaling Technology Cat# 3771, RRID:AB_330403)

      Curator: @ethanbadger

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    sciencedirect.com/science/article/pii/S221112471930539X
  67. Nov 2018
  68. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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      Curator: @evieth

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    ncbi.nlm.nih.gov/pmc/articles/PMC5979332/
  69. www.sciencedirect.com www.sciencedirect.com
    JAK/STAT3-Regulated Fatty Acid β-Oxidation Is Critical for Breast Cancer Stem Cell Self-Renewal and Chemoresistance
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    1. scibot 05 Nov 2018
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      Curator: @Jmenke

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    sciencedirect.com/science/article/pii/S1550413117306691
  70. europepmc.org europepmc.org
    Jak2-mediated phosphorylation of Atoh1 is critical for medulloblastoma growth.
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    1. scibot 05 Nov 2018
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      Curator: @evieth

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      (Cell Signaling Technology Cat# 3771S, RRID:AB_330403)

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    europepmc.org/articles/PMC5736349/