1,282 Matching Annotations
  1. Nov 2023
  2. www.sciencedirect.com www.sciencedirect.com
    GLP-1 and GIP receptors signal through distinct β-arrestin 2-dependent pathways to regulate pancreatic β cell function
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    1. scibot 02 Nov 2023
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      DOI: 10.1016/j.celrep.2023.113326

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    sciencedirect.com/science/article/pii/S2211124723013384
  3. Oct 2023
  4. 52.53.155.43 52.53.155.43
    bqad159-html.html
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    1. scibot 31 Oct 2023
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      DOI: 10.1210/endocr/bqad159

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    52.53.155.43/fadb698104ccd541263e8069783171593188288f/bqad159-html.html
  5. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A Novel ASCT2 Inhibitor, C118P, Blocks Glutamine Transport and Exhibits Antitumour Efficacy in Breast Cancer
    1
    1. scibot 31 Oct 2023
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      DOI: 10.3390/cancers15205082

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    ncbi.nlm.nih.gov/pmc/articles/PMC10605716/
  6. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Palmitate and glucose increase amyloid precursor protein in extracellular vesicles: Missing link between metabolic syndrome and Alzheimer's disease
    1
    1. scibot 31 Oct 2023
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      DOI: 10.1002/jev2.12340

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    ncbi.nlm.nih.gov/pmc/articles/PMC10613125/
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    KANK1 shapes focal adhesions by orchestrating protein binding, mechanical force sensing, and phase separation
    1
    1. scibot 28 Oct 2023
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      DOI: 10.1016/j.celrep.2023.113321

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    sciencedirect.com/science/article/pii/S2211124723013335
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    Naringenin improves muscle endurance via activation of the Sp1-ERRγ transcriptional axis
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    1. scibot 28 Oct 2023
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      DOI: 10.1016/j.celrep.2023.113288

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    sciencedirect.com/science/article/pii/S2211124723013001
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    HDL inhibits pancreatic acinar cell NLRP3 inflammasome activation and protect against acinar cell pyroptosis in acute pancreatitis
    1
    1. scibot 28 Oct 2023
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      DOI: 10.1016/j.intimp.2023.110950

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    sciencedirect.com/science/article/pii/S1567576923012754
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    JNK mediates cell death by promoting the ubiquitination of the apurinic/apyrimidinic endonuclease APE1
    1
    1. scibot 28 Oct 2023
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      DOI: 10.1016/j.celrep.2023.113123

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    sciencedirect.com/science/article/pii/S221112472301135X
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    Hypoxia-driven protease legumain promotes immunosuppression in glioblastoma
    1
    1. scibot 28 Oct 2023
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      DOI: 10.1016/j.xcrm.2023.101238

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    sciencedirect.com/science/article/pii/S2666379123004159
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    Collagen 1-mediated CXCL1 secretion in tumor cells activates fibroblasts to promote radioresistance of esophageal cancer
    1
    1. scibot 27 Oct 2023
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      DOI: 10.1016/j.celrep.2023.113270

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    sciencedirect.com/science/article/pii/S2211124723012822
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    Synergistic antitumor efficacy of rMV-Hu191 and Olaparib in pancreatic cancer by generating oxidative DNA damage and ROS-dependent apoptosis
    1
    1. scibot 27 Oct 2023
      RRID:AB_330

      DOI: 10.1016/j.tranon.2023.101812

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    sciencedirect.com/science/article/pii/S1936523323001985
  14. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    LINE-1 activation in the cerebellum drives ataxia
    1
    1. scibot 20 Oct 2023
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      DOI: 10.1016/j.neuron.2022.08.011

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    ncbi.nlm.nih.gov/pmc/articles/PMC9588660/
  15. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Fasudil-modified macrophages reduce inflammation and regulate the immune response in experimental autoimmune encephalomyelitis
    1
    1. scibot 20 Oct 2023
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      DOI: 10.4103/1673-5374.379050

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    ncbi.nlm.nih.gov/pmc/articles/PMC10581551/
  16. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Proteostasis is differentially modulated by inhibition of translation initiation or elongation
    1
    1. scibot 20 Oct 2023
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      DOI: 10.7554/eLife.76465

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    ncbi.nlm.nih.gov/pmc/articles/PMC10581687/
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    Antiangiogenic Action of JZL184 on Endothelial Cells via Inhibition of VEGF Expression in Hypoxic Lung Cancer Cells
    1
    1. scibot 18 Oct 2023
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      DOI: 10.3390/cells12192332

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    ncbi.nlm.nih.gov/pmc/articles/PMC10572003/
  18. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Non-Psychoactive Phytocannabinoids Inhibit Inflammation-Related Changes of Human Coronary Artery Smooth Muscle and Endothelial Cells
    1
    1. scibot 18 Oct 2023
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      DOI: 10.3390/cells12192389

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    ncbi.nlm.nih.gov/pmc/articles/PMC10571842/
  19. www.science.org www.science.org
    The midnolin-proteasome pathway catches proteins for ubiquitination-independent degradation
    1
    1. scibot 17 Oct 2023
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      DOI: 10.1126/science.adh5021

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    science.org/doi/10.1126/science.adh5021
  20. onlinelibrary.wiley.com onlinelibrary.wiley.com
    STAT3 modulates CD4+ T mitochondrial dynamics and function in aging
    1
    1. scibot 17 Oct 2023
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      DOI: 10.1111/acel.13996

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    onlinelibrary.wiley.com/doi/10.1111/acel.13996
  21. 52.53.155.43 52.53.155.43
    ASCL1-ERK1/2 Axis: ASCL1 restrains ERK1/2 via the dual specificity phosphatase DUSP6 to promote survival of a subset of neuroendocrine lung cancers
    1
    1. scibot 14 Oct 2023
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      DOI: 10.1101/2023.06.15.545148

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    52.53.155.43/3932de370933c2759897a986a0751f177eee572e/2023.06.15.545148v1.full-html.html
  22. www.sciencedirect.com www.sciencedirect.com
    Gonacin: A germ cell-derived hormone with glucogenic, orexigenic, and gonadal activities
    1
    1. scibot 14 Oct 2023
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      DOI: 10.1016/j.isci.2023.108065

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    sciencedirect.com/science/article/pii/S2589004223021429
  23. www.sciencedirect.com www.sciencedirect.com
    Neutrophils resist ferroptosis and promote breast cancer metastasis through aconitate decarboxylase 1
    1
    1. scibot 13 Oct 2023
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      DOI: 10.1016/j.cmet.2023.09.004

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    sciencedirect.com/science/article/pii/S1550413123003364
  24. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Lysosome damage triggers direct ATG8 conjugation and ATG2 engagement via non-canonical autophagy
    1
    1. scibot 12 Oct 2023
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      DOI: 10.1083/jcb.202303078

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    ncbi.nlm.nih.gov/pmc/articles/PMC10561555/
  25. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Dendritic distribution of autophagosomes underlies pathway-selective induction of LTD
    1
    1. scibot 06 Oct 2023
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      DOI: 10.1016/j.celrep.2023.112898

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    ncbi.nlm.nih.gov/pmc/articles/PMC10528062/
  26. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    SREBP-1 upregulates lipophagy to maintain cholesterol homeostasis in brain tumor cells
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    1. scibot 06 Oct 2023
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      DOI: 10.1016/j.celrep.2023.112790

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    ncbi.nlm.nih.gov/pmc/articles/PMC10528745/
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    Irisin reduces amyloid-β by inducing the release of neprilysin from astrocytes following downregulation of ERK-STAT3 signaling
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    1. scibot 06 Oct 2023
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      DOI: 10.1016/j.neuron.2023.08.012

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    sciencedirect.com/science/article/pii/S0896627323006232
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    CPSF6 regulates alternative polyadenylation and proliferation of cancer cells through phase separation
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    1. scibot 06 Oct 2023
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      DOI: 10.1016/j.celrep.2023.113197

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    sciencedirect.com/science/article/pii/S2211124723012093
  29. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Kinome reprogramming is a targetable vulnerability in ESR1 fusion-driven breast cancer
    1
    1. scibot 06 Oct 2023
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      DOI: 10.1158/0008-5472.CAN-22-3484

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    ncbi.nlm.nih.gov/pmc/articles/PMC10543968/
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    Acquisition of Neural Fate by Combination of BMP Blockade and Chromatin Modification
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    1. scibot 06 Oct 2023
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      DOI: 10.1016/j.isci.2023.107887

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    ncbi.nlm.nih.gov/pmc/articles/PMC10522999/
  31. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Interferon-α promotes neo-antigen formation and preferential HLA-B-restricted antigen presentation in pancreatic β-cells
    2
    1. scibot 05 Oct 2023
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      DOI: 10.1101/2023.09.15.557918

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      DOI: 10.1101/2023.09.15.557918

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    ncbi.nlm.nih.gov/pmc/articles/PMC10516036/
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    ONC201/TIC10 enhances durability of mTOR inhibitor everolimus in metastatic ER+ breast cancer
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    1. scibot 05 Oct 2023
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      DOI: 10.7554/eLife.85898

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    ncbi.nlm.nih.gov/pmc/articles/PMC10541180/
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    mTORC1 stimulates cell growth through SAM synthesis and m6A mRNA-dependent control of protein synthesis
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      DOI: 10.1016/j.molcel.2021.03.009

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    sciencedirect.com/science/article/pii/S1097276521001775
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    Neutrophil extracellular traps enhance S. aureus skin colonization by oxidative stress induction and downregulation of epidermal barrier genes
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    sciencedirect.com/science/article/pii/S2211124723011609
  35. Sep 2023
  36. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Splicing regulation of GFPT1 muscle-specific isoform and its roles in glucose metabolisms and neuromuscular junction
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      DOI: 10.1016/j.isci.2023.107746

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    ncbi.nlm.nih.gov/pmc/articles/PMC10514471/
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    Essential role of the amino-terminal region of Drosha for the Microprocessor function
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      DOI: 10.1016/j.isci.2023.107971

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    sciencedirect.com/science/article/pii/S2589004223020485
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    Discordant interactions between YAP1 and polycomb group protein SCML2 determine cell fate
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    sciencedirect.com/science/article/pii/S2589004223020412
  39. www.nature.com www.nature.com
    Multi-omics profiling reveals rhythmic liver function shaped by meal timing
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      DOI: 10.1038/s41467-023-41759-9

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    nature.com/articles/s41467-023-41759-9
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    Heteronemin promotes iron-dependent cell death in pancreatic cancer
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    1. scibot 30 Sep 2023
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      DOI: 10.1007/s00210-023-02736-7

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    link.springer.com/article/10.1007/s00210-023-02736-7
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    Underpinning the food matrix regulation of post-exercise myofibrillar protein synthesis by comparing salmon ingestion versus the sum of its isolated nutrients in healthy young adults
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      DOI: 10.1016/j.tjnut.2023.02.037

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    sciencedirect.com/science/article/pii/S0022316623352799
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    Increased alpha-synuclein and neuroinflammation in the substantia nigra triggered by systemic inflammation are reversed by targeted inhibition of the receptor for advanced glycation end products (RAGE)
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      DOI: 10.1111/jnc.15956

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    onlinelibrary.wiley.com/doi/10.1111/jnc.15956
  43. 52.53.155.43 52.53.155.43
    British J Pharmacology - 2023 - Su-html.html
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    An Fgr kinase inhibitor attenuates sepsis-associated encephalopathy by ameliorating mitochondrial dysfunction, oxidative stress, and neuroinflammation via the SIRT1/PGC-1α signaling pathway
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    NAT10-mediated ac4C tRNA modification promotes EGFR mRNA translation and gefitinib resistance in cancer
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    Elevated FBXW10 drives hepatocellular carcinoma tumorigenesis via AR-VRK2 phosphorylation-dependent GAPDH ubiquitination in male transgenic mice
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    Reprogramming of Iron Metabolism Confers Ferroptosis Resistance in ECM-Detached Cells
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    Exhaustion-associated cholesterol deficiency dampens the cytotoxic arm of antitumor immunity
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    CDKN2A deletion remodels lipid metabolism to prime glioblastoma for ferroptosis
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    PROX1 induction by autolysosomal activity stabilizes persister-like state of colon cancer via feedback repression of the NOX1-mTORC1 pathway
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    Transcriptional and metabolic programs promote the expansion of follicular helper T cells in lupus-prone mice
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    Cancer-cell-derived fumarate suppresses the anti-tumor capacity of CD8+ T cells in the tumor microenvironment
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    Cell-surface anchoring of Listeria adhesion protein on L. monocytogenes is fastened by internalin B for pathogenesis
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    Repurposing ceritinib induces DNA damage and enhances PARP inhibitor responses in high-grade serous ovarian carcinoma
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    Intracellular Adhesion Molecule-1 Improves Responsiveness to Immune Checkpoint Inhibitor by Activating CD8+ T Cells
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    An SPNS1-dependent lysosomal lipid transport pathway that enables cell survival under choline limitation
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    TC-G 1008 facilitates epileptogenesis by acting selectively at the GPR39 receptor but non-selectively activates CREB in the hippocampus of pentylenetetrazole-kindled mice
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    Integrative genetic analysis identifies FLVCR1 as a plasma-membrane choline transporter in mammals
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    Cancer Cell Resistance to IFNγ Can Occur via Enhanced Double-Strand Break Repair Pathway Activity
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    A kinome-wide CRISPR screen identifies CK1α as a target to overcome enzalutamide resistance of prostate cancer
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    Autocrine activation of MAPK signaling mediates intrinsic tolerance to androgen deprivation in LY6D prostate cancer cells
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    Mitoxantrone and Mitoxantrone-Loaded Iron Oxide Nanoparticles Induce Cell Death in Human Pancreatic Ductal Adenocarcinoma Cell Spheroids
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    Release of Histone H3K4-reading transcription factors from chromosomes in mitosis is independent of adjacent H3 phosphorylation
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    Identifying signatures of EV secretion in metastatic breast cancer through functional single-cell profiling
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    The APE2 nuclease is essential for DNA double-strand break repair by microhomology-mediated end joining
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    Phosphate Depletion in Insulin-Insensitive Skeletal Muscle Drives AMPD Activation and Sarcopenia in Chronic Kidney DIsease
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    Loss of the Volume-regulated Anion Channel Components LRRC8A and LRRC8D Limits Platinum Drug Efficacy
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    An optimized protocol to detect protein ubiquitination and activation by ubiquitination assay in vivo and CCK-8 assay
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    Structural features of the Notch ankyrin domain-Deltex WWE2 domain heterodimer determined by NMR spectroscopy and functional implications
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