1,290 Matching Annotations
  1. Sep 2020
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    The Natural Compound Notopterol Binds and Targets JAK2/3 to Ameliorate Inflammation and Arthritis
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    sciencedirect.com/science/article/pii/S2211124720311475
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    The Cdc48 Complex Alleviates the Cytotoxicity of Misfolded Proteins by Regulating Ubiquitin Homeostasis
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    Targeting Endogenous K-RAS for Degradation through the Affinity-Directed Protein Missile System
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    HSPGs glypican‐1 and glypican‐4 are human neuronal proteins characteristic of different neural phenotypes
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    SARS-CoV-2 ORF3b is a potent interferon antagonist whose activity is increased by a naturally occurring elongation variant
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    Differential Cellular Response to Translocated Toxic Effectors and Physical Penetration by the Type VI Secretion System
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    sciencedirect.com/science/article/pii/S2211124720307464
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    Induction of BDNF expression in layer II/III and layer V neurons of the motor cortex is essential for motor learning
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    Nicotinamide Mononucleotide Supplementation Reverses the Declining Quality of Maternally Aged Oocytes
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    KAP1 Is a Chromatin Reader that Couples Steps of RNA Polymerase II Transcription to Sustain Oncogenic Programs
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    sciencedirect.com/science/article/pii/S1097276520302665
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    Regulation of Nucleotide Metabolism and Germline Proliferation in Response to Nucleotide Imbalance and Genotoxic Stresses by EndoU Nuclease
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    sciencedirect.com/science/article/pii/S2211124720300759
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    Hepatitis Delta Virus histone mimicry drives the recruitment of chromatin remodelers for viral RNA replication
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    Lats1/2 Sustain Intestinal Stem Cells and Wnt Activation through TEAD-Dependent and Independent Transcription
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    Zika Virus Targets Glioblastoma Stem Cells through a SOX2-Integrin αvβ5 Axis
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    Metformin Enhances Autophagy and Normalizes Mitochondrial Function to Alleviate Aging-Associated Inflammation
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    Pimozide Alleviates Hyperglycemia in Diet-Induced Obesity by Inhibiting Skeletal Muscle Ketone Oxidation
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    A novel compound DBZ ameliorates neuroinflammation in LPS-stimulated microglia and ischemic stroke rats: Role of Akt(Ser473)/GSK3β(Ser9)-mediated Nrf2 activation
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    mTOR Signaling and SREBP Activity Increase FADS2 Expression and Can Activate Sapienate Biosynthesis
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    Human-iPSC-Derived Cardiac Stromal Cells Enhance Maturation in 3D Cardiac Microtissues and Reveal Non-cardiomyocyte Contributions to Heart Disease
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    sciencedirect.com/science/article/pii/S1934590920302022
  21. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Knocking Out Non-muscle Myosin II in Retinal Ganglion Cells Promotes Long-Distance Optic Nerve Regeneration
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    Formation of Human Neuroblastoma in Mouse-Human Neural Crest Chimeras
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    sciencedirect.com/science/article/pii/S1934590920300540
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    L ARP7 Is a BRCA1 Ubiquitinase Substrate and Regulates Genome Stability and Tumorigenesis
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  24. physoc.onlinelibrary.wiley.com physoc.onlinelibrary.wiley.com
    Acute and chronic effects of resistance training on skeletal muscle markers of mitochondrial remodeling in older adults
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      DOI: 10.14814/phy2.14526

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    The endothelial barrier is not rate-limiting to insulin action in the myocardium of male mice
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      DOI: 10.1210/endocr/bqaa029

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    Ceramide analog SACLAC modulates sphingolipid levels and Mcl-1 splicing to induce apoptosis in acute myeloid leukemia
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      DOI: 10.1158/1541-7786.MCR-19-0619

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    p53 Integrates Temporal WDR5 Inputs during Neuroectoderm and Mesoderm Differentiation of Mouse Embryonic Stem Cells
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    Muscle function and homeostasis require cytokine inhibition of AKT activity in Drosophila
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      DOI: 10.7554/eLife.51595

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    Flotillin-Dependent Membrane Microdomains Are Required for Functional Phagolysosomes against Fungal Infections
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    TMEM173 Drives Lethal Coagulation in Sepsis
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    Genome-wide Screens Implicate Loss of Cullin Ring Ligase 3 in Persistent Proliferation and Genome Instability in TP53-Deficient Cells
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    Multiple Signaling Roles of CD3ε and Its Application in CAR-T Cell Therapy
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    BIS-INDOLE DERIVED NUCLEAR RECEPTOR 4A1 (NR4A1, Nur77) LIGANDS AS INHIBITORS OF ENDOMETRIOSIS
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    Replication Stress Induces ATR/CHK1-Dependent Nonrandom Segregation of Damaged Chromosomes
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    Response of Retinal Pigment Epithelium (RPE)‐Choroid Explants to Thermal Stimulation Therapy of the RPE (TSR)
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  36. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Diverse dystonin gene mutations cause distinct patterns of Dst isoform deficiency and phenotypic heterogeneity in Dystonia musculorum mice
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    The role of Rif1 in telomere length regulation is separable from its role in origin firing
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      DOI: 10.7554/eLife.58066

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    Non-Canonical Caspase Activity Antagonizes p38 MAPK Stress-Priming Function to Support Development
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    Cep97 Is Required for Centriole Structural Integrity and Cilia Formation in Drosophila
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    Replication Study: A coding-independent function of gene and pseudogene mRNAs regulates tumour biology
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    Hypercapnia Exacerbates the Blood–Brain Barrier Disruption Via Promoting HIF-1a Nuclear Translocation in the Astrocytes of the Hippocampus: Implication in Further Cognitive Impairment in Hypoxemic Adult Rats
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    PRMT1 Is Recruited via DNA-PK to Chromatin Where It Sustains the Senescence-Associated Secretory Phenotype in Response to Cisplatin
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    Suppression of Membranous LRP5 Recycling, Wnt/β-Catenin Signaling, and Colon Carcinogenesis by 15-LOX-1 Peroxidation of Linoleic Acid in PI3P
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    Critical Roles of Translation Initiation and RNA Uridylation in Endogenous Retroviral Expression and Neural Differentiation in Pluripotent Stem Cells
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    SFPQ Is an FTO-Binding Protein that Facilitates the Demethylation Substrate Preference
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    Recognition of Semaphorin Proteins by P. sordellii Lethal Toxin Reveals Principles of Receptor Specificity in Clostridial Toxins
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    An Integrated Gene Expression Landscape Profiling Approach to Identify Lung Tumor Endothelial Cell Heterogeneity and Angiogenic Candidates
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    Treatment-Induced Tumor Dormancy through YAP-Mediated Transcriptional Reprogramming of the Apoptotic Pathway
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    Quantitative and Dynamic Catalogs of Proteins Released during Apoptotic and Necroptotic Cell Death
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    Altered Adhesion and Migration of Human Mesenchymal Stromal Cells under Febrile Temperature Stress Involves NF-κβ Pathway
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    Molecular Basis of Zinc-Dependent Endocytosis of Human ZIP4 Transceptor
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    Complement Signals Determine Opposite Effects of B Cells in Chemotherapy-Induced Immunity
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    iTAG-RNA Isolates Cell-Specific Transcriptional Responses to Environmental Stimuli and Identifies an RNA-Based Endocrine Axis
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    PDGF-B Is Required for Development of the Glymphatic System
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    A Bartonella Effector Acts as Signaling Hub for Intrinsic STAT3 Activation to Trigger Anti-inflammatory Responses
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    Genetic loss of AMPK-glycogen binding destabilizes AMPK and disrupts metabolism
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    Plasmodium falciparum translational machinery condones polyadenosine repeats
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    Magnetic Susceptibility Difference-induced Nucleus Positioning in Gradient Ultra-high Magnetic Field
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    A drug screening toolkit based on the –1 ribosomal frameshifting of SARS-CoV-2
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    Dual Regulation of Histone Methylation by mTOR Complexes Controls Glioblastoma Tumor Cell Growth via EZH2 and SAM
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    YBX1 Indirectly Targets Heterochromatin-Repressed Inflammatory Response-Related Apoptosis Genes through Regulating CBX5 mRNA
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    Immobilization leads to alterations in intracellular phosphagen and creatine transporter content in human skeletal muscle | American Journal of Physiology-Cell Physiology
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    A self-sustaining endocytic-based loop promotes breast cancer plasticity leading to aggressiveness and pro-metastatic behavior
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      anti‐mouse IgG, HRP‐linked

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  79. pubs.acs.org pubs.acs.org
    Proximal Biotinylation Based Combinatory Approach for Isolating Integral Plasma Membrane Proteins
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    Thalidomide promotes degradation of SALL4, a transcription factor implicated in Duane Radial Ray Syndrome
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    Endogenous itaconate is not required for particulate matter-induced NRF2 expression or inflammatory response
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  83. www.sciencedirect.com www.sciencedirect.com
    Mitochondrial Regulation of the 26S Proteasome
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  84. Jan 2020
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    Slc6a8-Mediated Creatine Uptake and Accumulation Reprogram Macrophage Polarization via Regulating Cytokine Responses
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    Postmortem Cortex Samples Identify Distinct Molecular Subtypes of ALS: Retrotransposon Activation, Oxidative Stress, and Activated Glia
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    The E3 Ubiquitin Ligase Mind Bomb 1 Controls Adenovirus Genome Release at the Nuclear Pore Complex
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    Microbial Metabolite Signaling Is Required for Systemic Iron Homeostasis
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    Zika Virus NS3 Mimics a Cellular 14-3-3-Binding Motif to Antagonize RIG-I- and MDA5-Mediated Innate Immunity
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    Metabolic Control of Astrocyte Pathogenic Activity via cPLA2-MAVS
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    HIV-1 Vif Triggers Cell Cycle Arrest by Degrading Cellular PPP2R5 Phospho-regulators
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    RNase L Reprograms Translation by Widespread mRNA Turnover Escaped by Antiviral mRNAs
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    SUMO-Chain-Regulated Proteasomal Degradation Timing Exemplified in DNA Replication Initiation
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    PKC-delta mediates mineralocorticoid receptor activation by angiotensin II to modulate smooth muscle cell function
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      DOI: 10.1210/en.2019-00258

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    RAD51AP1 Is an Essential Mediator of Alternative Lengthening of Telomeres
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    SENP2 Suppresses Necdin Expression to Promote Brown Adipocyte Differentiation
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    Effect of early-stage autophagy inhibition in BRAF V600E autophagy-dependent brain tumor cells
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    The N-Degron Pathway Mediates ER-phagy
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    VEGAS as a Platform for Facile Directed Evolution in Mammalian Cells
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    CRISPR/Cas9 Screens Reveal Multiple Layers of B cell CD40 Regulation
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    STING-Mediated IFI16 Degradation Negatively Controls Type I Interferon Production
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    PPEF2 Opposes PINK1-Mediated Mitochondrial Quality Control by Dephosphorylating Ubiquitin
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    Mesothelial Cell HIF1α Expression Is Metabolically Downregulated by Metformin to Prevent Oncogenic Tumor-Stromal Crosstalk
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    C2‐lacking isoform of Nedd4‐2 regulates excitatory synaptic strength through GluA1 ubiquitination‐independent mechanisms
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    Discovery and Development of TMPRSS6 Inhibitors Modulating Hepcidin Levels in Human Hepatocytes
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    The Hippo Pathway Effector TAZ Regulates Ferroptosis in Renal Cell Carcinoma
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    miRNA551b-3p Activates an Oncostatin Signaling Module for the Progression of Triple-Negative Breast Cancer
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    Neutralization of the Positive Charges on Histone Tails by RNA Promotes an Open Chromatin Structure
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    Loss of Slug Compromises DNA Damage Repair and Accelerates Stem Cell Aging in Mammary Epithelium
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    The Receptor Kinases BAK1/SERK4 Regulate Ca2+ Channel-Mediated Cellular Homeostasis for Cell Death Containment
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    Generation of three induced pluripotent cell lines (iPSCs) from an Aicardi-Goutières syndrome (AGS) patient harboring a deletion in the genomic locus of the sterile alpha motif and HD domain containing protein 1 (SAMHD1)
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    TRPML1 Promotes Protein Homeostasis in Melanoma Cells by Negatively Regulating MAPK and mTORC1 Signaling
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    RUVBL1/RUVBL2 ATPase Activity Drives PAQosome Maturation, DNA Replication and Radioresistance in Lung Cancer
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    Spatial Chromosome Folding and Active Transcription Drive DNA Fragility and Formation of Oncogenic MLL Translocations
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    Neuronal Ca2+‐dependent activator protein 1 (NCDAP1) induces neuronal cell death by activating p53 pathway following traumatic brain injury
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    Sox17 Regulates a Program of Oligodendrocyte Progenitor Cell Expansion and Differentiation during Development and Repair
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    Metalloprotease-Dependent Attenuation of BMP Signaling Restricts Cardiac Neural Crest Cell Fate
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    Autoinhibition Mechanism of the Ubiquitin-Conjugating Enzyme UBE2S by Autoubiquitination
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    Immunometabolic Cross-Talk and Regulation of Endocrine and Metabolic Functions: Transgenic overexpression of CTRP3 prevents alcohol-induced hepatic triglyceride accumulation
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    Cross-Microbial Protection via Priming a Conserved Immune Co-Receptor through Juxtamembrane Phosphorylation in Plants
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    Fructose-1,6-Bisphosphatase 2 Inhibits Sarcoma Progression by Restraining Mitochondrial Biogenesis
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    SENP1-Sirt3 Signaling Controls Mitochondrial Protein Acetylation and Metabolism
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    Multiomics Profiling Establishes the Polypharmacology of FDA-Approved CDK4/6 Inhibitors and the Potential for Differential Clinical Activity
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    Structural Basis of Paxillin Recruitment by Kindlin-2 in Regulating Cell Adhesion
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    A PRMT5-RNF168-SMURF2 Axis Controls H2AX Proteostasis
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    Induced pluripotent stem cell line (PEIi003-A) derived from an apparently healthy male individual.
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    A multimolecular signaling complex including PrPC and LRP1 is strictly dependent on lipid rafts and is essential for the function of tissue Plasminogen Activator
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    N-cadherin-regulated FGFR ubiquitination and degradation control mammalian neocortical projection neuron migration
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    Small-Molecule and CRISPR Screening Converge to Reveal Receptor Tyrosine Kinase Dependencies in Pediatric Rhabdoid Tumors
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    Locomotor training with adjuvant testosterone preserves cancellous bone and promotes muscle plasticity in male rats after severe spinal cord injury
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    Oncogene Amplification in Growth Factor Signaling Pathways Renders Cancers Dependent on Membrane Lipid Remodeling
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    Phosphorylation-mediated interactions with TOPBP1 couple 53BP1 and 9-1-1 to control the G1 DNA damage checkpoint
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    Orchestration of Processing Body Dynamics and mRNA Decay in Arabidopsis Immunity
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    Directed RNase H Cleavage of Nascent Transcripts Causes Transcription Termination
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    Donepezil‐induced oligodendrocyte differentiation is mediated through estrogen receptors
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    Protective effects of GHK-Cu in bleomycin-induced pulmonary fibrosis via anti-oxidative stress and anti-inflammation pathways
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    Liver-Type Glutaminase GLS2 Is a Druggable Metabolic Node in Luminal-Subtype Breast Cancer
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    PRDM16 Maintains Homeostasis of the Intestinal Epithelium by Controlling Region-Specific Metabolism
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    Amyloid-like Assembly Activates a Phosphatase in the Developing Drosophila Embryo
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    Suppression of p16 Induces mTORC1-Mediated Nucleotide Metabolic Reprogramming
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    Modulation of RNA Condensation by the DEAD-Box Protein eIF4A
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    Mitochondrial Damage and Activation of the STING Pathway Lead to Renal Inflammation and Fibrosis
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    YAP/TAZ Activation Drives Uveal Melanoma Initiation and Progression
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    mTORC1 Activation Requires DRAM-1 by Facilitating Lysosomal Amino Acid Efflux
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    Photocrosslinking Activity-Based Probes for Ubiquitin RING E3 Ligases
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    Fascin Controls Metastatic Colonization and Mitochondrial Oxidative Phosphorylation by Remodeling Mitochondrial Actin Filaments
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    Regulation of Autophagic Flux by the 20S Proteasome
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    Mitigating Antagonism between Transcription and Proliferation Allows Near-Deterministic Cellular Reprogramming
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    Calcifediol decreases interleukin-6 secretion by cultured human trophoblasts from GDM pregnancies
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    Cancer Cells Upregulate NRF2 Signaling to Adapt to Autophagy Inhibition
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    Synthesis and Characterization of Specific Reverse Transcriptase Inhibitors for Mammalian LINE-1 Retrotransposons
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    Activity‐dependent cleavage of dyskinesia‐related proline‐rich transmembrane protein 2 (PRRT2) by calpain in mouse primary cortical neurons
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    IL-36 promotes anti-viral immunity by boosting sensitivity to IFN-α/β in IRF1 dependent and independent manners
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    Jumonji Inhibitors Overcome Radioresistance in Cancer through Changes in H3K4 Methylation at Double-Strand Breaks
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    Multi-level Proteomics Identifies CT45 as a Chemosensitivity Mediator and Immunotherapy Target in Ovarian Cancer
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      RRID:AB_330924

      Curator: @Jmenke

      Resource used:

      (Cell Signaling Technology Cat# 7076, RRID:AB_330924)

      SciCrunch record: RRID:AB_330924

      Alternate resolvers: SciCrunch xml N2T identifiers.org

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      RRID:AB_330924 RRIDCUR:Validated
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    onlinelibrary.wiley.com/doi/full/10.1002/jcp.27239
  199. journals.plos.org journals.plos.org
    A high-throughput screen of real-time ATP levels in individual cells reveals mechanisms of energy failure
    1
    1. scibot 05 Nov 2018
      anti-mouse IgG, HRP-linked secondary antibody

      Curator: @evieth

      Curator note: Cell Signaling Technology Cat# 7076,

      Resource used:

      (Cell Signaling Technology Cat# 7076, RRID:AB_330924)

      SciCrunch record: RRID:AB_330924

      Alternate resolvers: SciCrunch xml N2T identifiers.org

      What is this?

      RRID:AB_330924 RRIDCUR:Missing
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    journals.plos.org/plosbiology/article
  200. www.sciencedirect.com www.sciencedirect.com
    Hippocampal CB1 Receptors Control Incidental Associations
    1
    1. scibot 05 Nov 2018
      AB_330924

      Curator: @Jmenke

      Resource used:

      (Cell Signaling Technology Cat# 7076, RRID:AB_330924)

      SciCrunch record: RRID:AB_330924

      Alternate resolvers: SciCrunch xml N2T identifiers.org

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      RRID:AB_330924 RRIDCUR:Validated
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    sciencedirect.com/science/article/pii/S0896627318306871
  201. www.ncbi.nlm.nih.govhttp: www.ncbi.nlm.nih.govhttp:
    Non-canonical Activation of the DNA Sensing Adaptor STING by ATM and IFI16 Mediates NF-κB Signaling after Nuclear DNA Damage
    1
    1. scibot 05 Nov 2018
      RRID:AB_330924

      Curator: @evieth

      Resource used:

      (Cell Signaling Technology Cat# 7076, RRID:AB_330924)

      SciCrunch record: RRID:AB_330924

      Alternate resolvers: SciCrunch xml N2T identifiers.org

      What is this?

      RRID:AB_330924 RRIDCUR:Validated
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    ncbi.nlm.nih.govhttp://europepmc.org/articles/PMC6127031/