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181 Matching Annotations

Aug 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

The Tacrine‐Induced Endoplasmic Reticulum Stress in AChE‐Expressed Cells Leads to Improper Assembly and Transport of the Oligomeric Enzyme: Reversal by Trehalose

1
1. scibot 07 Aug 2025
  
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  RRID:AB_330951
  
  DOI: 10.1111/jnc.70178
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12322807/
Jul 2025
www.cell.com www.cell.com

Imeglimin suppresses glucagon secretion and induces a loss of α cell identity

1
1. scibot 29 Jul 2025
  
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  RRID:AB_330951
  
  DOI: 10.1016/j.xcrm.2025.102254
  
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cell.com/cell-reports-medicine/fulltext/S2666-3791(25)00327-1
52.53.155.43 52.53.155.43

pnas.2422752122.sapp-html.html

1
1. scibot 19 Jul 2025
  
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  AB_330951
  
  DOI: 10.1073/pnas.2422752122
  
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52.53.155.43/722297ea6ed68b0f9652bebe39ded86a7b52b759/pnas.2422752122.sapp-html.html
www.sciencedirect.com www.sciencedirect.com

Glucose restriction shapes pre-metastatic innate immune landscapes in the lung through exosomal TRAIL

1
1. scibot 16 Jul 2025
  
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  RRID:AB_330951
  
  DOI: 10.1016/j.cell.2025.06.027
  
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sciencedirect.com/science/article/pii/S0092867425007287
Jun 2025
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Hyperacute response proteins synthesized on γ-tubulin-FTO-MARK4 translation microdomains regulate cancer’s acute stress response

1
1. scibot 18 Jun 2025
  
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  DOI: 10.1016/j.celrep.2025.115871
  
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sciencedirect.com/science/article/pii/S2211124725006424
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Mechanism by which the molecular glue-like verteporfin induces IRE1α dimerization and activation to synergize with AKT inhibition in breast cancer

1
1. scibot 05 Jun 2025
  
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  RRID:AB_330951
  
  DOI: 10.1016/j.chembiol.2025.05.004
  
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sciencedirect.com/science/article/pii/S2451945625001655
May 2025
dx.doi.org dx.doi.org

FVB But Not B6 Mice Carrying the Thr92Ala-Dio2 Polymorphism Have Impaired Thyroid Hormonogenesis and Goiter

1
1. scibot 21 May 2025
  
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  DOI: 10.1210/endocr/bqaf046
  
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dx.doi.org/10.1210/endocr/bqaf046
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Prkra dimer senses double-stranded RNAs to dictate global translation efficiency

1
1. scibot 18 May 2025
  
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  RRID:AB_330951
  
  DOI: 10.1016/j.molcel.2025.04.005
  
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sciencedirect.com/science/article/pii/S1097276525003089
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Multiomics reveal biomolecular shifts and ER stress in sleep-restricted women affecting NSC functions

1
1. scibot 18 May 2025
  
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  RRID:AB_330951
  
  DOI: 10.1016/j.isci.2025.112510
  
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sciencedirect.com/science/article/pii/S2589004225007710
www.cell.com www.cell.com

IRE1α promotes phagosomal calcium flux to enhance macrophage fungicidal activity

1
1. scibot 17 May 2025
  
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  RRID:AB_330951
  
  DOI: 10.1016/j.celrep.2025.115694
  
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cell.com/cell-reports/fulltext/S2211-1247(25)00465-6
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UFMylation safeguards human hepatocyte differentiation and liver homeostasis by regulating ribosome dissociation

1
1. scibot 17 May 2025
  
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  RRID:AB_330951
  
  DOI: 10.1016/j.celrep.2025.115686
  
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sciencedirect.com/science/article/pii/S2211124725004577
Apr 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Effective recognition of double-stranded RNA does not require activation of cellular inflammation

1
1. scibot 16 Apr 2025
  
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  RRID:AB_330951
  
  DOI: 10.1126/sciadv.ads6498
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11980852/
Mar 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Bromocriptine improves glucose tolerance in obese mice via central dopamine D2 receptor-independent mechanism

1
1. scibot 28 Mar 2025
  
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  RRID:AB_330951
  
  DOI: 10.1371/journal.pone.0320157
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11940610/
www.biorxiv.org www.biorxiv.org

The carnosinase dipeptidase CNDP1 is a novel metabolic vulnerability in brain metastasis

2
1. scibot 24 Mar 2025
  
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  RRID: AB_330951
  
  DOI: 10.1101/2025.03.18.644053
  
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2. scibot 24 Mar 2025
  
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  RRID:AB_330951
  
  DOI: 10.1101/2025.03.18.644053
  
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biorxiv.org/content/10.1101/2025.03.18.644053v1
52.53.155.43 52.53.155.43

1-s2.0-S2589004225003980-main-html.html

1
1. scibot 04 Mar 2025
  
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  AB_330951
  
  DOI: 10.1016/j.isci.2025.112138
  
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52.53.155.43/5cb7aee35160970f93d9910e96369ff58c9b35b0/1-s2.0-S2589004225003980-main-html.html
Feb 2025
www.sciencedirect.com www.sciencedirect.com

A neurodegenerative cellular stress response linked to dark microglia and toxic lipid secretion

7
1. scibot 07 Feb 2025
  
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  RRID:AB_330951
  
  DOI: 10.1016/j.neuron.2024.11.018
  
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2. scibot 06 Feb 2025
  
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  RRID:AB_330951
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:AB_330951
3. scibot 05 Feb 2025
  
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  RRID:AB_330951
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:AB_330951
4. scibot 04 Feb 2025
  
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  RRID:AB_330951
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:AB_330951
5. scibot 03 Feb 2025
  
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  RRID:AB_330951
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:AB_330951
6. scibot 02 Feb 2025
  
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  RRID:AB_330951
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:AB_330951
7. scibot 01 Feb 2025
  
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  RRID:AB_330951
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
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sciencedirect.com/science/article/pii/S0896627324008754
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A methyltransferase-independent role for METTL1 in tRNA aminoacylation and oncogenic transformation

1
1. scibot 04 Feb 2025
  
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  RRID:AB_330951
  
  DOI: 10.1016/j.molcel.2025.01.003
  
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sciencedirect.com/science/article/pii/S1097276525000036
Jan 2025
www.sciencedirect.com www.sciencedirect.com

A neurodegenerative cellular stress response linked to dark microglia and toxic lipid secretion

31
1. scibot 31 Jan 2025
  
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  RRID:AB_330951
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:AB_330951
2. scibot 30 Jan 2025
  
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  RRID:AB_330951
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:AB_330951
3. scibot 29 Jan 2025
  
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  RRID:AB_330951
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:AB_330951
4. scibot 28 Jan 2025
  
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  RRID:AB_330951
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:AB_330951
5. scibot 27 Jan 2025
  
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  RRID:AB_330951
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:AB_330951
6. scibot 26 Jan 2025
  
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  RRID:AB_330951
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:AB_330951
7. scibot 25 Jan 2025
  
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  RRID:AB_330951
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:AB_330951
8. scibot 24 Jan 2025
  
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  RRID:AB_330951
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:AB_330951
9. scibot 23 Jan 2025
  
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  RRID:AB_330951
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:AB_330951
10. scibot 22 Jan 2025
  
  in Public
  
  RRID:AB_330951
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:AB_330951
11. scibot 21 Jan 2025
  
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  RRID:AB_330951
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:AB_330951
12. scibot 20 Jan 2025
  
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  RRID:AB_330951
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:AB_330951
13. scibot 19 Jan 2025
  
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  RRID:AB_330951
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:AB_330951
14. scibot 18 Jan 2025
  
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  RRID:AB_330951
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:AB_330951
15. scibot 17 Jan 2025
  
  in Public
  
  RRID:AB_330951
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:AB_330951
16. scibot 16 Jan 2025
  
  in Public
  
  RRID:AB_330951
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:AB_330951
17. scibot 15 Jan 2025
  
  in Public
  
  RRID:AB_330951
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:AB_330951
18. scibot 14 Jan 2025
  
  in Public
  
  RRID:AB_330951
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:AB_330951
19. scibot 13 Jan 2025
  
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  RRID:AB_330951
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:AB_330951
20. scibot 12 Jan 2025
  
  in Public
  
  RRID:AB_330951
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:AB_330951
21. scibot 11 Jan 2025
  
  in Public
  
  RRID:AB_330951
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:AB_330951
22. scibot 10 Jan 2025
  
  in Public
  
  RRID:AB_330951
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:AB_330951
23. scibot 09 Jan 2025
  
  in Public
  
  RRID:AB_330951
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:AB_330951
24. scibot 08 Jan 2025
  
  in Public
  
  RRID:AB_330951
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:AB_330951
25. scibot 07 Jan 2025
  
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  RRID:AB_330951
  
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  RRID:AB_330951
26. scibot 06 Jan 2025
  
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  RRID:AB_330951
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:AB_330951
27. scibot 05 Jan 2025
  
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  RRID:AB_330951
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:AB_330951
28. scibot 04 Jan 2025
  
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  RRID:AB_330951
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:AB_330951
29. scibot 03 Jan 2025
  
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  RRID:AB_330951
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:AB_330951
30. scibot 02 Jan 2025
  
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  RRID:AB_330951
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:AB_330951
31. scibot 01 Jan 2025
  
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  RRID:AB_330951
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
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A neurodegenerative cellular stress response linked to dark microglia and toxic lipid secretion

8
1. scibot 31 Dec 2024
  
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  RRID:AB_330951
2. scibot 30 Dec 2024
  
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  RRID:AB_330951
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:AB_330951
3. scibot 29 Dec 2024
  
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  RRID:AB_330951
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:AB_330951
4. scibot 28 Dec 2024
  
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  RRID:AB_330951
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:AB_330951
5. scibot 27 Dec 2024
  
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  RRID:AB_330951
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:AB_330951
6. scibot 26 Dec 2024
  
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  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:AB_330951
7. scibot 25 Dec 2024
  
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  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:AB_330951
8. scibot 24 Dec 2024
  
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  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
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Full-length direct RNA sequencing uncovers stress granule-dependent RNA decay upon cellular stress

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eEF2K regulates pain through translational control of BDNF

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Temperature perception by ER UPR promotes preventive innate immunity and longevity

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Endoplasmic reticulum associated degradation preserves neurons viability by maintaining endoplasmic reticulum homeostasis

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DDI2 protease controls embryonic development and inflammation via TCF11/NRF1

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Viral hijacking of hnRNPH1 unveils a G-quadruplex-driven mechanism of stress control

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CRISPR-Cas9 Screens Identify the RNA Helicase DDX3X as a Repressor of C9ORF72 (GGGGCC)n Repeat-Associated Non-AUG Translation

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Islet cell stress induced by insulin-degrading enzyme deficiency promotes regeneration and protection from autoimmune diabetes

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Glucose hypometabolism prompts RAN translation and exacerbates C9orf72-related ALS/FTD phenotypes

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ER-stress in mouse serotonin neurons triggers a depressive phenotype alleviated by ketamine targeting eIF2α signaling

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Feb 2024
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Visualization of translation reorganization upon persistent ribosome collision stress in mammalian cells

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Alternative polyadenylation determines the functional landscape of inverted Alu repeats

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Migrasomal autophagosomes relieve endoplasmic reticulum stress in glioblastoma cells

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Downregulation of nutrition sensor GCN2 in macrophages contributes to poor wound healing in diabetes

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Inhibition of lipid synthesis by the HIV integrase strand transfer inhibitor elvitegravir in primary rat oligodendrocyte cultures

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Overexpression of ORMDL3 confers sexual dimorphism in diet-induced non-alcoholic steatohepatitis

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EDEM1 regulates the insulin mRNA level by inhibiting the endoplasmic reticulum stress-induced IRE1/JNK/c-Jun pathway

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Ablation of ERO1A induces lethal endoplasmic reticulum stress responses and immunogenic cell death to activate anti-tumor immunity

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Hepatic levels of S-adenosylmethionine regulate the adaptive response to fasting

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Optogenetic control of the integrated stress response reveals proportional encoding and the stress memory landscape

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Generation of host-directed and virus-specific antivirals using targeted protein degradation promoted by small molecules and viral RNA mimics

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Nutrient-dependent regulation of β-cell proinsulin content

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Nuclear translocation of an aminoacyl-tRNA synthetase may mediate a chronic “integrated stress response”

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Berberine ameliorates obesity by inducing GDF15 secretion by brown adipocytes

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A novel IRE1 kinase inhibitor for adjuvant glioblastoma treatment.

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KS10076, a chelator for redox-active metal ions, induces ROS-mediated STAT3 degradation in autophagic cell death and eliminates ALDH1+ stem cells

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Compounds activating VCP D1 ATPase enhance both autophagic and proteasomal neurotoxic protein clearance

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Stress granule formation inhibits stress-induced apoptosis by selectively sequestering executioner caspases

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SARS-CoV-2 viral protein Nsp2 stimulates translation under normal and hypoxic conditions

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Large neutral amino acid levels tune perinatal neuronal excitability and survival

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Arginine shortage induces replication stress and confers genotoxic resistance by inhibiting histone H4 translation and promoting PCNA ubiquitination

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Endoplasmic reticulum associated degradation is essential for maintaining the viability or function of mature myelinating cells in adults

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Protein folding stress potentiates NLRP1 and CARD8 inflammasome activation

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Valproate reduces retinal ganglion cell apoptosis in rats... : Neural Regeneration Research

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Synthetic Essentiality of Tryptophan 2,3-dioxygenase 2 in APC-Mutated Colorectal Cancer

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Hypothalamic orexin prevents non-alcoholic steatohepatitis and hepatocellular carcinoma in obesity

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Ablation of the endoplasmic reticulum stress kinase PERK induces paraptosis and type I interferon to promote anti-tumor T cell responses

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Mitochondrial double-stranded RNAs govern the stress response in chondrocytes to promote osteoarthritis development

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GCN2 inhibition sensitizes arginine-deprived hepatocellular carcinoma cells to senolytic treatment

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Neuron-specific translational control shift ensures proteostatic resilience during ER stress

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cd-21-0680-html.html

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Disruption of the lipolysis pathway results in stem cell death through a sterile immunity-like pathway in adult Drosophila

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Cytosolic aspartate aminotransferase moonlights as a ribosome-binding modulator of Gcn2 activity during oxidative stress

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Asthmatic bronchial smooth muscle increases rhinovirus replication within the bronchial epithelium

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Paracrine signal emanating from stressed cardiomyocytes aggravates inflammatory microenvironment in diabetic cardiomyopathy

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Intermittent bolus feeding does not enhance protein synthesis, myonuclear accretion, or lean growth more than continuous feeding in a premature piglet model

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Aggravation of pulmonary fibrosis after knocking down the aryl hydrocarbon receptor in the insulin-like growth factor 1 receptor pathway

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Identification of an endoplasmic reticulum proteostasis modulator that enhances insulin production in pancreatic β cells

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MEK inhibition overcomes chemoimmunotherapy resistance by inducing CXCL10 in cancer cells

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AMPK-PERK axis represses oxidative metabolism and enhances apoptotic priming of mitochondria in acute myeloid leukemia

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Integrated stress response regulates GDF15 secretion from adipocytes, preferentially suppresses appetite for a high-fat diet and improves obesity

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Mitophagy antagonism by ZIKV reveals Ajuba as a regulator of PINK1 signaling, PKR-dependent inflammation, and viral invasion of tissues

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Co-opting regulation bypass repair as a gene correction strategy for monogenic diseases

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Endosomal trafficking and DNA damage checkpoint kinases dictate survival to replication stress by regulating amino acid uptake and protein synthesis

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Fatty acids impact sarcomere integrity through myristoylation and ER homeostasis

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Fat body Ire1 regulates lipid homeostasis through the Xbp1s-FoxO axis in Drosophila

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Notch-induced endoplasmic reticulum-associated degradation governs mouse thymocyte β−selection

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Untitled document

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Hypoexcitability precedes denervation in the large fast-contracting motor units in two unrelated mouse models of ALS

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Oral administration of a new HRI activator as a new strategy to improve high‐fat‐diet‐induced glucose intolerance, hepatic steatosis, and hypertriglyceridaemia through FGF21

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Ribosome ADP-ribosylation inhibits translation and maintains proteostasis in cancers

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Inhibition of YTHDF2 triggers proteotoxic cell death in MYC-driven breast cancer

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HIV-induced neuroinflammation inhibits oligodendrocyte maturation via glutamate-dependent activation of the PERK arm of the integrated stress response

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May 2021
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Expression of the Neuronal tRNA n-Tr20 Regulates Synaptic Transmission and Seizure Susceptibility

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The Nuclear SUMO-Targeted Ubiquitin Quality Control Network Regulates the Dynamics of Cytoplasmic Stress Granules

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m6A Modification Prevents Formation of Endogenous Double-Stranded RNAs and Deleterious Innate Immune Responses during Hematopoietic Development

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Defects in translation-dependent quality control pathways lead to convergent molecular and neurodevelopmental pathology

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The adverse metabolic effects of branched-chain amino acids are mediated by isoleucine and valine

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The mTORC1-mediated activation of ATF4 promotes protein and glutathione synthesis downstream of growth signals

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Reduced Na+K+‐ATPase activity may reduce amino acid uptake in IUGR fetal sheep muscle despite unchanged ex vivo amino acid transporter activity

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Tripartite suppression of fission yeast TORC1 signaling by the GATOR1-Sea3 complex, the TSC complex, and Gcn2 kinase

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Jan 2021
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G3BPs tether the TSC complex to lysosomes and suppress mTORC1 signaling

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The Integrated UPR and ERAD in Oligodendrocytes Maintain Myelin Thickness in Adults by Regulating Myelin Protein Translation

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Yeast Nuak1 phosphorylates histone H3 threonine 11 in low glucose stress by the cooperation of AMPK and CK2 signaling

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CB1R regulates soluble leptin receptor levels via CHOP, contributing to hepatic leptin resistance

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Saturated Fatty Acids Promote GDF15 Expression in Human Macrophages through the PERK/eIF2/CHOP Signaling Pathway

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Nov 2020
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GTPBP1 resolves paused ribosomes to maintain neuronal homeostasis

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Quantitative Proteomics Analysis of Lytic KSHV Infection in Human Endothelial Cells Reveals Targets of Viral Immune Modulation

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Sep 2020
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Differential effects of integrase strand transfer inhibitors, elvitegravir and raltegravir, on oligodendrocyte maturation: A role for the integrated stress response

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onlinelibrary.wiley.com/doi/10.1002/glia.23902
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MANF ablation causes prolonged activation of the UPR without neurodegeneration in the mouse midbrain dopamine system

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Endoplasmic reticulum associated degradation is required for maintaining endoplasmic reticulum homeostasis and viability of mature Schwann cells in adults

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The integrated stress response induces R-loops and hinders replication fork progression

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Pan-retroviral Nucleocapsid-Mediated Phase Separation Regulates Genomic RNA Positioning and Trafficking

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Blockade of Oncogenic NOTCH1 with the SERCA Inhibitor CAD204520 in T Cell Acute Lymphoblastic Leukemia

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Nucleocytoplasmic Proteomic Analysis Uncovers eRF1 and Nonsense-Mediated Decay as Modifiers of ALS/FTD C9orf72 Toxicity

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ncbi.nlm.nih.gov/pmc/articles/PMC7272217/
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CRISPR-Cas9 Screens Identify the RNA Helicase DDX3X as a Repressor of C9ORF72 (GGGGCC)n Repeat-Associated Non-AUG Translation

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No evidence for cell‐to‐cell transmission of the unfolded protein response in cell culture

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Long-Term Culture Captures Injury-Repair Cycles of Colonic Stem Cells

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Amyloid-Beta (Aβ) Plaques Promote Seeding and Spreading of Alpha-Synuclein and Tau in a Mouse Model of Lewy Body Disorders with Aβ Pathology

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Hepatic nitric oxide synthase 1 adaptor protein regulates glucose homeostasis and hepatic insulin sensitivity in obese mice depending on its PDZ binding domain

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Expression of the double‐stranded RNA‐dependent kinase PKR influences osteosarcoma attachment independent growth, migration, and invasion

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Polyamines Control eIF5A Hypusination, TFEB Translation, and Autophagy to Reverse B Cell Senescence

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Suppression of Ribosomal Pausing by eIF5A Is Necessary to Maintain the Fidelity of Start Codon Selection

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System-wide Profiling of RNA-Binding Proteins Uncovers Key Regulators of Virus Infection

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Mast Cells Induce Blood Brain Barrier Damage in SCD by Causing Endoplasmic Reticulum Stress in the Endothelium

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  DOI: 10.3389/fncel.2019.00056
  
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Untitled document

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High‐fat diet intake modulates maternal intestinal adaptations to pregnancy and results in placental hypoxia, as well as altered fetal gut barrier proteins and immune markers

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Translational and HIF-1α-Dependent Metabolic Reprogramming Underpin Metabolic Plasticity and Responses to Kinase Inhibitors and Biguanides

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Target-Based Discovery of an Inhibitor of the Regulatory Phosphatase PPP1R15B

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The UPR Activator ATF6 Responds to Proteotoxic and Lipotoxic Stress by Distinct Mechanisms

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Dietary Intake of Curcumin Improves eIF2 Signaling and Reduces Lipid Levels in the White Adipose Tissue of Obese Mice

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Stress Granule Assembly Disrupts Nucleocytoplasmic Transport

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Low-Protein Diet Induces IRE1α-Dependent Anticancer Immunosurveillance

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Chemical hypoxia‐induced integrated stress response activation in oligodendrocytes is mediated by the transcription factor nuclear factor (erythroid‐derived 2)‐like 2 (NRF2)

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Phospho-Rasputin Stabilization by Sec16 Is Required for Stress Granule Formation upon Amino Acid Starvation

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Genome-Scale Networks Link Neurodegenerative Disease Genes to α-Synuclein through Specific Molecular Pathways

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Translational control of auditory imprinting and structural plasticity by eIF2α

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