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A Hotspot Phosphorylation Site on SHP2 Drives Oncoprotein Activation and Drug Resistance

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1. scibot 07 Sep 2025
  
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  RRID:AB_331072
  
  DOI: 10.21203/rs.3.rs-7032881/v1
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12340909/
Aug 2025
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A Hotspot Phosphorylation Site on SHP2 Drives Oncoprotein Activation and Drug Resistance

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1. scibot 11 Aug 2025
  
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  RRID:AB_331072
  
  DOI: 10.1101/2025.06.11.659120
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12262427/
Jul 2025
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Modulation of FGF pathway signaling and vascular differentiation using designed oligomeric assemblies

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1. scibot 15 Jul 2025
  
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  RRID:AB_331072
  
  DOI: 10.1016/j.cell.2024.05.025
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11246234/
Jan 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Landscape of Clinical Resistance Mechanisms to FGFR Inhibitors in FGFR2-Altered Cholangiocarcinoma

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1. scibot 10 Jan 2024
  
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  RRID:AB_331072
  
  DOI: 10.1158/1078-0432.CCR-23-1317
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10767308/
Dec 2023
52.53.155.43 52.53.155.43

ccr-23-1317-html.html

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1. scibot 01 Dec 2023
  
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  DOI: 10.1158/1078-0432.ccr-23-1317
  
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52.53.155.43/eb06d63ced7d6b4d34065d25e0eab223f52bfb41/ccr-23-1317-html.html
Sep 2023
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

RLY-4008, the first highly selective FGFR2 inhibitor with activity across FGFR2 alterations and resistance mutations

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1. scibot 08 Sep 2023
  
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  RRID:AB_331072
  
  DOI: 10.1158/2159-8290.CD-23-0475
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10481131/
Jul 2023
52.53.155.43 52.53.155.43

cd-23-0475-html.html

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1. scibot 13 Jul 2023
  
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  RRID:AB_331072
  
  DOI: 10.1158/2159-8290.cd-23-0475
  
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52.53.155.43/ab02200bf4457c1e8196af2525f73574a3d0dd99/cd-23-0475-html.html
Apr 2023
www.nature.com www.nature.com

Single targeting of MET in EGFR-mutated and MET-amplified non-small cell lung cancer

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1. scibot 18 Apr 2023
  
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  RRID:AB_33107
  
  DOI: 10.1038/s41416-023-02264-4
  
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nature.com/articles/s41416-023-02264-4
Apr 2022
www.sciencedirect.com www.sciencedirect.com

Cellular signals converge at the NOX2-SHP-2 axis to induce reductive carboxylation in cancer cells

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1. scibot 21 Apr 2022
  
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  RRID:AB_331072
  
  DOI: 10.1016/j.chembiol.2022.03.010
  
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sciencedirect.com/science/article/pii/S2451945622001271
Mar 2022
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Receptor tyrosine kinases regulate signal transduction through a liquid-liquid phase separated state

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1. scibot 02 Mar 2022
  
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  RRID:AB_331072
  
  DOI: 10.1016/j.molcel.2022.02.005
  
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sciencedirect.com/science/article/pii/S1097276522001101
Sep 2020
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Mechanical Stress Regulates Epithelial Tissue Integrity and Stiffness through the FGFR/Erk2 Signaling Pathway during Embryogenesis

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1. scibot 17 Sep 2020
  
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  RRID:AB_331072
  
  DOI: 10.1016/j.celrep.2020.02.074
  
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  RRID:AB_331072 RRIDCUR:Validated
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sciencedirect.com/science/article/pii/S2211124720302436
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Tumor Microenvironment-Derived NRG1 Promotes Antiandrogen Resistance in Prostate Cancer

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1. scibot 17 Sep 2020
  
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  RRID:AB_331072
  
  DOI: 10.1016/j.ccell.2020.06.005
  
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  RRID:AB_331072 RRIDCUR:Validated
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sciencedirect.com/science/article/pii/S1535610820303093
Jan 2020
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Small-Molecule and CRISPR Screening Converge to Reveal Receptor Tyrosine Kinase Dependencies in Pediatric Rhabdoid Tumors

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1. scibot 13 Jan 2020
  
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  RRID:AB_331072
  
  DOI: 10.1016/j.celrep.2019.07.021
  
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  RRID:AB_331072 RRIDCUR:Validated
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sciencedirect.com/science/article/pii/S2211124719309118
Nov 2018
europepmc.org europepmc.org

Untitled document

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1. scibot 05 Nov 2018
  
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  RRID:AB_331072
  
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europepmc.org/articles/PMC5779225/