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  1. Last 7 days
  2. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Burdock miR8175 in diet improves insulin resistance induced by obesity in mice through food absorption
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    1. scibot 28 Apr 2024
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    ncbi.nlm.nih.gov/pmc/articles/PMC11039404/
  3. Apr 2024
  4. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Islet resident macrophage-derived miR-155 promotes β-cell decompensation via targeting PDX1
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    ncbi.nlm.nih.gov/pmc/articles/PMC10993184/
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    Insulin receptor signaling engages bladder urothelial defenses that limit urinary tract infection
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    1. scibot 11 Apr 2024
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    sciencedirect.com/science/article/pii/S2211124724003358
  6. Feb 2024
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    Hepatocyte CHRNA4 mediates the MASH-promotive effects of immune cell-produced acetylcholine and smoking exposure in mice and humans
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    sciencedirect.com/science/article/pii/S1550413123004126
  8. Nov 2023
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    Insulin receptor loss impairs mammary tumorigenesis in mice
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    1. scibot 02 Nov 2023
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    sciencedirect.com/science/article/pii/S2211124723012639
  10. Sep 2023
  11. 52.53.155.43 52.53.155.43
    British J Pharmacology - 2023 - Dai-html.html
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    52.53.155.43/8d076c70ed36377d24eb7bc3686db861bc15751d/British J Pharmacology - 2023 - Dai-html.html
  12. Jul 2023
  13. dx.doi.org dx.doi.org
    Pigment Epithelium-Derived Factor, a Novel Adipokine, Contributes to Gestational Diabetes Mellitus
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    1. scibot 29 Jul 2023
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  14. Mar 2023
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    SUCNR1 signaling in adipocytes controls energy metabolism by modulating circadian clock and leptin expression
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    sciencedirect.com/science/article/pii/S1550413123000827
  16. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Loss of E-cadherin Induces IGF1R Activation and Reveals a Targetable Pathway in Invasive Lobular Breast Carcinoma
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    1. scibot 05 Mar 2023
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    ncbi.nlm.nih.gov/pmc/articles/PMC9444924/
  17. Jan 2023
  18. www.sciencedirect.com www.sciencedirect.com
    SLC7A14 imports GABA to lysosomes and impairs hepatic insulin sensitivity via inhibiting mTORC2
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    1. scibot 12 Jan 2023
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    sciencedirect.com/science/article/pii/S2211124722018885
  19. Dec 2022
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    Pro-prion, as a membrane adaptor protein for E3 ligase c-Cbl, facilitates the ubiquitination of IGF-1R, promoting melanoma metastasis
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    1. scibot 24 Dec 2022
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  21. Nov 2022
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    Grabody B, an IGF1 receptor-based shuttle, mediates efficient delivery of biologics across the blood-brain barrier
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    1. scibot 22 Nov 2022
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    sciencedirect.com/science/article/pii/S2667237522002351
  23. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A ketogenic diet in combination with gemcitabine increases survival in pancreatic cancer KPC mice
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    1. scibot 19 Nov 2022
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    Androgens improve ovarian follicle function impaired by glucocorticoids through an androgen-IGF1-FSH synergistic effect
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    ncbi.nlm.nih.gov/pmc/articles/PMC9627217/
  25. Oct 2022
  26. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The proprotein convertase furin regulates the development of thymic epithelial cells to ensure central immune tolerance
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    1. scibot 26 Oct 2022
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  27. Mar 2022
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    Procr functions as a signaling receptor and is essential for the maintenance and self-renewal of mammary stem cells
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    sciencedirect.com/science/article/pii/S2211124722002893
  29. www.nature.com www.nature.com
    Symmetric and asymmetric receptor conformation continuum induced by a new insulin
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    nature.com/articles/s41589-022-00981-0
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    Methylene-bridge tryptophan fatty acylation regulates PI3K-AKT signaling and glucose uptake
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    sciencedirect.com/science/article/pii/S2211124722002455
  31. Dec 2021
  32. www.sciencedirect.com www.sciencedirect.com
    Translational and post-translational control of human naïve versus primed pluripotency
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      DOI: 10.1016/j.isci.2021.103645

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    sciencedirect.com/science/article/pii/S2589004221016151
  33. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Aging Does Not Exacerbate Muscle Loss During Denervation and Lends Unique Muscle-Specific Atrophy Resistance With Akt Activation
    1
    1. scibot 17 Dec 2021
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      DOI: 10.3389/fphys.2021.779547

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    ncbi.nlm.nih.gov/pmc/articles/PMC8669767/
  34. Oct 2021
  35. www.sciencedirect.com www.sciencedirect.com
    Homocysteine inhibits pro-insulin receptor cleavage and causes insulin resistance via protein cysteine-homocysteinylation
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    1. scibot 13 Oct 2021
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      DOI: 10.1016/j.celrep.2021.109821

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    sciencedirect.com/science/article/pii/S2211124721012857
  36. Aug 2021
  37. www.sciencedirect.com www.sciencedirect.com
    An extensive and dynamic trans-omic network illustrating prominent regulatory mechanisms in response to insulin in the liver
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    sciencedirect.com/science/article/pii/S2211124721010032
  38. academic.oup.com academic.oup.com
    Differential Actions of Estrogen Receptor α and β via Non-Genomic Signaling in Human Prostate Stem and Progenitor Cells
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      DOI: 10.1210/en.2019-00177

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    academic.oup.com/endo/article/160/11/2692/5551999
  39. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.14553
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    Isthmin-1 is an adipokine that promotes glucose uptake and improves glucose tolerance and hepatic steatosis
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    sciencedirect.com/science/article/pii/S1550413121003260
  41. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
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    bpspubs.onlinelibrary.wiley.com/doi/full/10.1111/bph.14553
  42. Jan 2021
  43. www.sciencedirect.com www.sciencedirect.com
    Expression of miRNA-29 in Pancreatic β Cells Promotes Inflammation and Diabetes via TRAF3
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    sciencedirect.com/science/article/pii/S2211124720315655
  44. Sep 2020
  45. www.jbc.org www.jbc.org
    Disrupting phosphatase SHP2 in macrophages protects mice from high-fat diet–induced hepatic steatosis and insulin resistance by elevating IL-18 levels
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      DOI: 10.1074/jbc.RA119.011840

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  46. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    Essential Functions of Glycans in Human Epithelia Dissected by a CRISPR-Cas9-Engineered Human Organotypic Skin Model
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    pubmed.ncbi.nlm.nih.gov/32710848/
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    Phenotypic Screen with TSC-Deficient Neurons Reveals Heat-Shock Machinery as a Druggable Pathway for mTORC1 and Reduced Cilia
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    sciencedirect.com/science/article/pii/S2211124720307609
  48. www.mdpi.com www.mdpi.com
    IGF-1 Signalling Regulates Mitochondria Dynamics and Turnover through a Conserved GSK-3β–Nrf2–BNIP3 Pathway
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      Rabbit anti-phospho-IGF-1R

      DOI: 10.3390/cells9010147

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    mdpi.com/2073-4409/9/1/147
  49. journals.physiology.org journals.physiology.org
    Lactational metformin exposure programs offspring white adipose tissue glucose homeostasis and resilience to metabolic stress in a sex-dependent manner | American Journal of Physiology-Endocrinology and Metabolism
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      monoclonal rabbit phospho-IGF-I receptor β (Tyr1135/1136)/insulin receptor-β

      DOI: 10.1152/ajpendo.00473.2019

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    journals.physiology.org/doi/full/10.1152/ajpendo.00473.2019
  50. Jan 2020
  51. www.sciencedirect.com www.sciencedirect.com
    Hepatic nitric oxide synthase 1 adaptor protein regulates glucose homeostasis and hepatic insulin sensitivity in obese mice depending on its PDZ binding domain
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      DOI: 10.1016/j.ebiom.2019.08.033

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    sciencedirect.com/science/article/pii/S2352396419305584
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    Functional Redundancy between β1 and β3 Integrin in Activating the IR/Akt/mTORC1 Signaling Axis to Promote ErbB2-Driven Breast Cancer
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    sciencedirect.com/science/article/pii/S2211124719311726
  53. www.sciencedirect.com www.sciencedirect.com
    Lysosome Positioning Influences mTORC2 and AKT Signaling
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      DOI: 10.1016/j.molcel.2019.05.009

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    sciencedirect.com/science/article/pii/S1097276519303624
  54. www.sciencedirect.com www.sciencedirect.com
    Contrasting Effects of IGF Binding Protein-3 Expression in Mammary Tumor Cells and the Tumor Microenvironment
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    1. scibot 13 Jan 2020
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      DOI: 10.1016/j.yexcr.2018.11.006

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    sciencedirect.com/science/article/pii/S0014482718308218
  55. www.sciencedirect.com www.sciencedirect.com
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      DOI: 10.1016/j.celrep.2019.02.081

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    sciencedirect.com/science/article/pii/S2211124719302670
  56. Nov 2018
  57. www.sciencedirect.com www.sciencedirect.com
    Subversion of Systemic Glucose Metabolism as a Mechanism to Support the Growth of Leukemia Cells
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    sciencedirect.com/science/article/pii/S1535610818303763
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    In Vivo Decoding Mechanisms of the Temporal Patterns of Blood Insulin by the Insulin-AKT Pathway in the Liver
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    Insulin Signaling Regulates the FoxM1/PLK1/CENP-A Pathway to Promote Adaptive Pancreatic β Cell Proliferation
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