125 Matching Annotations
  1. Sep 2024
  2. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    FNIP1 suppresses colorectal cancer progression through inhibiting STAT3 phosphorylation and nuclear translocation
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    1. scibot 25 Sep 2024
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    ncbi.nlm.nih.gov/pmc/articles/PMC11389550/
  3. Aug 2024
  4. www.sciencedirect.com www.sciencedirect.com
    Mutant TP53 switches therapeutic vulnerability during gastric cancer progression within interleukin-6 family cytokines
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    1. scibot 21 Aug 2024
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    sciencedirect.com/science/article/pii/S2211124724009665
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    Therapeutic application of extracellular vesicular EGFR isoform D as a co-drug to target squamous cell cancers with tyrosine kinase inhibitors
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    1. scibot 01 Aug 2024
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    sciencedirect.com/science/article/pii/S1534580724004428
  6. Jul 2024
  7. www.mdpi.com www.mdpi.com
    Impact of Interleukin-6 Activation and Arthritis on Epidermal Growth Factor Receptor (EGFR) Activation in Sensory Neurons and the Spinal Cord
    1
    1. scibot 26 Jul 2024
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      DOI: 10.3390/ijms25137168

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    mdpi.com/1422-0067/25/13/7168
  8. www.sciencedirect.com www.sciencedirect.com
    Myeloid cells coordinately induce glioma cell-intrinsic and cell-extrinsic pathways for chemoresistance via GP130 signaling
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    1. scibot 25 Jul 2024
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    sciencedirect.com/science/article/pii/S2666379124003720
  9. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Extracellular domain shedding of the ALK receptor mediates neuroblastoma cell migration
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    1. scibot 24 Jul 2024
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    ncbi.nlm.nih.gov/pmc/articles/PMC8328392/
  10. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Decoding sunitinib resistance in ccRCC: Metabolic-reprogramming-induced ABAT and GABAergic system shifts
    1
    1. scibot 19 Jul 2024
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    ncbi.nlm.nih.gov/pmc/articles/PMC11295714/
  11. May 2024
  12. link.springer.com link.springer.com
    IL-17a promotes hepatocellular carcinoma by increasing FAP expression in hepatic stellate cells via activation of the STAT3 signaling pathway
    1
    1. scibot 15 May 2024
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      DOI: 10.1038/s41420-024-01995-4

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    link.springer.com/article/10.1038/s41420-024-01995-4
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    Transcription factor dynamics, oscillation, and functions in human enteroendocrine cell differentiation
    1
    1. scibot 14 May 2024
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    sciencedirect.com/science/article/pii/S1934590924001425
  14. Apr 2024
  15. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Anorexia-Induced Hypoleptinemia Drives Adaptations in the JAK2/STAT3 Pathway in the Ventral and Dorsal Hippocampus of Female Rats
    1
    1. scibot 30 Apr 2024
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    ncbi.nlm.nih.gov/pmc/articles/PMC11054075/
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    The antiprotozoal drug nitazoxanide improves experimental liver fibrosis in mice
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    1. scibot 16 Apr 2024
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    sciencedirect.com/science/article/pii/S0006295224001886
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    Central inhibition of HDAC6 re-sensitizes leptin signaling during obesity to induce profound weight loss
    1
    1. scibot 04 Apr 2024
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    sciencedirect.com/science/article/pii/S1550413124000536
  18. www.sciencedirect.com www.sciencedirect.com
    Cancer SLC6A6-mediated taurine uptake transactivates immune checkpoint genes and induces exhaustion in CD8+ T cells
    1
    1. scibot 02 Apr 2024
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    sciencedirect.com/science/article/pii/S0092867424003039
  19. Mar 2024
  20. 52.53.155.43 52.53.155.43
    Human seminal extracellular vesicles enhance endometrial receptivity through leukemia inhibitory factor
    2
    1. scibot 29 Mar 2024
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      DOI: 10.1210/endocr/bqae035

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    52.53.155.43/ef706d7fedeb9d14a9f80c03d77786b7f4c289d6/bqae035-html.html
  21. www.nature.com www.nature.com
    Angiotensin II type-2 receptor signaling facilitates liver injury repair and regeneration via inactivation of Hippo pathway
    1
    1. scibot 20 Mar 2024
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      DOI: 10.1038/s41401-024-01249-0

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    nature.com/articles/s41401-024-01249-0
  22. Feb 2024
  23. www.sciencedirect.com www.sciencedirect.com
    IL-37 dampens immunosuppressive functions of MDSCs via metabolic reprogramming in the tumor microenvironment
    1
    1. scibot 29 Feb 2024
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    sciencedirect.com/science/article/pii/S2211124724001633
  24. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Schisandrin B promotes hepatic differentiation from human umbilical cord mesenchymal stem cells
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    1. scibot 08 Feb 2024
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    ncbi.nlm.nih.gov/pmc/articles/PMC10844828/
  25. Jan 2024
  26. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    FK506 bypasses the effect of erythroferrone in cancer cachexia skeletal muscle atrophy
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    1. scibot 12 Jan 2024
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    ncbi.nlm.nih.gov/pmc/articles/PMC10772350/
  27. Dec 2023
  28. www.sciencedirect.com www.sciencedirect.com
    BACH1 changes microglial metabolism and affects astrogenesis during mouse brain development
    1
    1. scibot 16 Dec 2023
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      DOI: 10.1016/j.devcel.2023.11.018

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    sciencedirect.com/science/article/pii/S1534580723006160
  29. Nov 2023
  30. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Micheliolide exerts effects in myeloproliferative neoplasms through inhibiting STAT3/5 phosphorylation via covalent binding to STAT3/5 proteins
    2
    1. scibot 11 Nov 2023
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      DOI: 10.1097/BS9.0000000000000168

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    ncbi.nlm.nih.gov/pmc/articles/PMC10629731/
  31. Oct 2023
  32. onlinelibrary.wiley.com onlinelibrary.wiley.com
    STAT3 modulates CD4+ T mitochondrial dynamics and function in aging
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    1. scibot 17 Oct 2023
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      DOI: 10.1111/acel.13996

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    onlinelibrary.wiley.com/doi/10.1111/acel.13996
  33. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    High NEK2 expression in myeloid progenitors suppresses T cell immunity in multiple myeloma
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    1. scibot 14 Oct 2023
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      DOI: 10.1016/j.xcrm.2023.101214

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    pmc.ncbi.nlm.nih.gov/articles/PMC10591052/
  34. Sep 2023
  35. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Phase I Study of Acalabrutinib Plus Danvatirsen (AZD9150) in Relapsed/Refractory Diffuse Large B-Cell Lymphoma Including Circulating Tumor DNA Biomarker Assessment
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    1. scibot 07 Sep 2023
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      DOI: 10.1158/1078-0432.CCR-22-2483

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    ncbi.nlm.nih.gov/pmc/articles/PMC10472096/
  36. Aug 2023
  37. www.science.org www.science.org
    A virally encoded GPCR drives glioblastoma through feed-forward activation of the SK1-S1P1 signaling axis
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    1. scibot 29 Aug 2023
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      DOI: 10.1126/scisignal.ade6737

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    science.org/doi/10.1126/scisignal.ade6737
  38. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Cannabinoid receptor type 1 (CB1R) inhibits hypothalamic leptin signaling via β-arrestin1 in complex with TC-PTP and STAT3
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    1. scibot 03 Aug 2023
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      DOI: 10.1016/j.isci.2023.107207

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    ncbi.nlm.nih.gov/pmc/articles/PMC10392084/
  39. Jul 2023
  40. 52.53.155.43 52.53.155.43
    British J Pharmacology - 2023 - Chen - Anthelmintics nitazoxanide protects against experimental pulmonary fibrosis-html.html
    2
    1. scibot 21 Jul 2023
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      DOI: 10.1111/bph.16190

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    52.53.155.43/01e7f498781407a431fc8d9b3b9cdd8be1437af6/British J Pharmacology - 2023 - Chen - Anthelmintics nitazoxanide protects against experimental pulmonary fibrosis-html.html
  41. www.sciencedirect.com www.sciencedirect.com
    STAT3 regulates antiviral immunity by suppressing excessive interferon signaling
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    1. scibot 13 Jul 2023
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      DOI: 10.1016/j.celrep.2023.112806

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    sciencedirect.com/science/article/pii/S2211124723008173
  42. www.sciencedirect.com www.sciencedirect.com
    LYVE-1+ macrophages form a collaborative CCR5-dependent perivascular niche that influences chemotherapy responses in murine breast cancer
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      DOI: 10.1016/j.devcel.2023.06.006

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    sciencedirect.com/science/article/pii/S1534580723003040
  43. May 2023
  44. www.sciencedirect.com www.sciencedirect.com
    Enhanced mitochondrial fission inhibits triple-negative breast cancer cell migration through a ROS-dependent mechanism
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      DOI: 10.1016/j.isci.2023.106788

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    sciencedirect.com/science/article/pii/S2589004223008659
  45. Apr 2023
  46. www.sciencedirect.com www.sciencedirect.com
    CX3CR1hi macrophages sustain metabolic adaptation by relieving adipose-derived stem cell senescence in visceral adipose tissue
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    sciencedirect.com/science/article/pii/S2211124723004357
  47. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    MEK Inhibition Synergizes with TYK2 Inhibitors in NF1-Associated Malignant Peripheral Nerve Sheath Tumors
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      DOI: 10.1158/1078-0432.CCR-22-3722

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    ncbi.nlm.nih.gov/pmc/articles/PMC10102849/
  48. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    IL-6–GP130 signaling protects human hepatocytes against lipid droplet accumulation in humanized liver models
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      DOI: 10.1126/sciadv.adf4490

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    ncbi.nlm.nih.gov/pmc/articles/PMC10104468/
  49. www.science.org www.science.org
    IL-6–GP130 signaling protects human hepatocytes against lipid droplet accumulation in humanized liver models
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    science.org/doi/10.1126/sciadv.adf4490
  50. Mar 2023
  51. www.sciencedirect.com www.sciencedirect.com
    Phosphoenolpyruvate regulates the Th17 transcriptional program and inhibits autoimmunity
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    sciencedirect.com/science/article/pii/S2211124723002164
  52. Feb 2023
  53. www.sciencedirect.com www.sciencedirect.com
    Cationic amphiphilic antihistamines inhibit STAT3 via Ca2+-dependent lysosomal H+ efflux
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    sciencedirect.com/science/article/pii/S2211124723001481
  54. Dec 2022
  55. www.sciencedirect.com www.sciencedirect.com
    AKTIP loss is enriched in ERα-positive breast cancer for tumorigenesis and confers endocrine resistance
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    sciencedirect.com/science/article/pii/S2211124722017132
  56. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Blockage of Lamin-A/C loss diminishes the pro-inflammatory macrophage response
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  57. Nov 2022
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  111. onlinelibrary.wiley.com onlinelibrary.wiley.com
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  112. Jun 2021
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    Ca2+/calmodulin kinase II–dependent regulation of βIV-spectrin modulates cardiac fibroblast gene expression, proliferation, and contractility
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  115. May 2021
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    Loss of interleukin-10 receptor disrupts intestinal epithelial cell proliferation and skews differentiation towards the goblet cell fate
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    Mitohormesis in Hypothalamic POMC Neurons Mediates Regular Exercise-Induced High-Turnover Metabolism
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  120. Apr 2021
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  123. Feb 2021
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  130. Jan 2021
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    Ablation of STAT3 in Purkinje cells reorganizes cerebellar synaptic plasticity in long-term fear memory network
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    Metformin Enhances Autophagy and Normalizes Mitochondrial Function to Alleviate Aging-Associated Inflammation
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    Exome Sequencing Identifies Genes and Gene Sets Contributing to Severe Childhood Obesity, Linking PHIP Variants to Repressed POMC Transcription
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  137. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
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    Developmental and Tumor Angiogenesis Requires the Mitochondria-Shaping Protein Opa1
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  139. Jan 2020
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    Oncogenic Mutations Rewire Signaling Pathways by Switching Protein Recruitment to Phosphotyrosine Sites
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  143. Nov 2018
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    The Lineage-Defining Transcription Factors SOX2 and NKX2-1 Determine Lung Cancer Cell Fate and Shape the Tumor Immune Microenvironment
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    Combinatorial CRISPR/Cas9 Approach to Elucidate a Far-Upstream Enhancer Complex for Tissue-Specific Sox9 Expression
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    Therapeutic Ablation of Gain-of-Function Mutant p53 in Colorectal Cancer Inhibits Stat3-Mediated Tumor Growth and Invasion
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    Intestinal Epithelial Cell Autophagy Is Required to Protect against TNF-Induced Apoptosis during Chronic Colitis in Mice
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    Epigenetic Promoter DNA Methylation of miR-124 Promotes HIV-1 Tat-Mediated Microglial Activation via MECP2-STAT3 Axis
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    A novel de novo activating mutation in STAT3 identified in a patient with common variable immunodeficiency (CVID)
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    Long-Fiber Carbon Nanotubes Replicate Asbestos-Induced Mesothelioma with Disruption of the Tumor Suppressor Gene Cdkn2a (Ink4a/Arf)
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    Tissue-Specific Ablation of the LIF Receptor in the Murine Uterine Epithelium Results in Implantation Failure
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    academic.oup.com/endo/article/158/6/1916/3077227/Tissue-Specific-Ablation-of-the-LIF-Receptor-in
  159. academic.oup.com academic.oup.com
    Loss of Action via Neurotensin-Leptin Receptor Neurons Disrupts Leptin and Ghrelin-Mediated Control of Energy Balance
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    1. scibot 08 Nov 2017
      AB_331269

      Curator: @bandrow

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      (Cell Signaling Technology Cat# 4904, RRID:AB_331269)

      SciCrunch record: RRID:AB_331269

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      RRID:AB_331269
    2. scibot 08 Nov 2017
      AB_331269

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      (Cell Signaling Technology Cat# 4904, RRID:AB_331269)

      SciCrunch record: RRID:AB_331269

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      RRID:AB_331269
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    academic.oup.com/endo/article/158/5/1271/3065520/Loss-of-Action-via-Neurotensin-Leptin-Receptor
  160. www.sciencedirect.com www.sciencedirect.com
    Inhibition of Hematopoietic Cell Kinase Activity Suppresses Myeloid Cell-Mediated Colon Cancer Progression
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    1. scibot 08 Nov 2017
      AB_331269

      Curator: @Zeljana_Babic

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      (Cell Signaling Technology Cat# 4904, RRID:AB_331269)

      SciCrunch record: RRID:AB_331269

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      RRID:AB_331269 RRIDCUR:Validated
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    sciencedirect.com/science/article/pii/S1535610817301022