132 Matching Annotations
  1. Last 7 days
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    STK19 facilitates the clearance of lesion-stalled RNAPII during transcription-coupled DNA repair
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    1. scibot 21 Nov 2024
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    sciencedirect.com/science/article/pii/S0092867424012005
  3. Nov 2024
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    Regulatory mechanisms of strigolactone perception in rice
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    sciencedirect.com/science/article/pii/S0092867424011577
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    USP7 deubiquitinates KRAS and promotes non-small cell lung cancer
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    sciencedirect.com/science/article/pii/S2211124724012683
  6. Oct 2024
  7. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    P16INK4A drives RB1 degradation by UTP14A-catalyzed K810 ubiquitination
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    ncbi.nlm.nih.gov/pmc/articles/PMC11440251/
  8. Sep 2024
  9. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    BPS Publications
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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.17320
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    Myeloid beta-arrestin 2 depletion attenuates metabolic dysfunction-associated steatohepatitis via the metabolic reprogramming of macrophages
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    A Patient-Derived Cell Atlas Informs Precision Targeting of Glioblastoma
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    FYVE1/FREE1 is involved in glutamine-responsive TORC1 activation in plants
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  13. Aug 2024
  14. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Ubiquitin-specific peptidase 22 controls integrin-dependent cancer cell stemness and metastasis
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    MiR-4769-3p suppresses adipogenesis in systemic sclerosis by negatively regulating USP18/VDAC2 pathway
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    cell.com/iscience/abstract/S2589-0042(24)01708-5
  16. Jul 2024
  17. 52.53.155.43 52.53.155.43
    Importin-9 regulates chromosome segregation and packaging in Drosophila germ cells
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    Pro-survival signaling regulates lipophagy essential for multiple myeloma resistance to stress-induced death
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  19. Jun 2024
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    The HRD1-SEL1L ubiquitin ligase regulates stress granule homeostasis in couple with distinctive signaling branches of ER stress
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  21. May 2024
  22. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Glial fibrillary acidic protein is pathologically modified in Alexander disease
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  23. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    TRIM37 is a primate-specific E3 ligase for Huntingtin and accounts for the striatal degeneration in Huntington’s disease
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  24. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Mecp2 fine-tunes quiescence exit by targeting nuclear receptors
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  25. www.biorxiv.org www.biorxiv.org
    Adult-Onset Deletion of ATP13A2 in Mice Induces Progressive Nigrostriatal Pathway Dopaminergic Degeneration and Lysosomal Abnormalities
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    biorxiv.org/content/10.1101/2024.01.25.577280v1
  26. Apr 2024
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    Integrated drug profiling and CRISPR screening identify BCR::ABL1-independent vulnerabilities in chronic myeloid leukemia
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    sciencedirect.com/science/article/pii/S2666379124001903
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    Arachidonic acid released by PIK3CA mutant tumor cells triggers malignant transformation of colonic epithelium by inducing chromatin remodeling
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  29. www.nature.com www.nature.com
    Genetic and pharmacological reduction of CDK14 mitigates synucleinopathy
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  30. Mar 2024
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    Stabilization of AMPK/PFKL/RPIA in the Glycolytic Bodies Transduces IL6/STAT3 Signal in Hepatocarcinogenesis
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    The acetylase activity of Cdu1 regulates bacterial exit from infected cells by protecting Chlamydia effectors from degradation
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    ncbi.nlm.nih.gov/pmc/articles/PMC10942603/
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    Lysosomal damage sensing and lysophagy initiation by SPG20-ITCH
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    Discovery of SQSTM1/p62-dependent P-bodies that regulate the NLRP3 inflammasome
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    sciencedirect.com/science/article/pii/S2211124724002638
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    MOF-mediated acetylation of UHRF1 enhances UHRF1 E3 ligase activity to facilitate DNA methylation maintenance
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    sciencedirect.com/science/article/pii/S2211124724002365
  36. Feb 2024
  37. link.springer.com link.springer.com
    CircUSP1 as a novel marker promotes gastric cancer progression via stabilizing HuR to upregulate USP1 and Vimentin
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    Alternative polyadenylation determines the functional landscape of inverted Alu repeats
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  39. Jan 2024
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    hRpn13 shapes the proteome and transcriptome through epigenetic factors HDAC8, PADI4, and transcription factor NF-κB p50
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    sciencedirect.com/science/article/pii/S1097276523009802
  41. Dec 2023
  42. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Ubiquiton—An inducible, linkage-specific polyubiquitylation tool
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    ncbi.nlm.nih.gov/pmc/articles/PMC10804999/
  43. Nov 2023
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    Lidocaine induces apoptosis in head and neck squamous cell carcinoma through activation of bitter taste receptor T2R14
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    sciencedirect.com/science/article/pii/S2211124723014493
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    HRS mediates tumor immune evasion by regulating proteostasis-associated interferon pathway activation
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    sciencedirect.com/science/article/pii/S2211124723013645
  46. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Mass isolation of staged Drosophila pupal intestines for analysis of protein ubiquitylation
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    ncbi.nlm.nih.gov/pmc/articles/PMC10682243/
  47. Oct 2023
  48. link.springer.com link.springer.com
    MLKL regulates Cx43 ubiquitinational degradation and mediates neuronal necroptosis in ipsilateral thalamus after focal cortical infarction
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      DOI: 10.1186/s13041-023-01064-4

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    link.springer.com/article/10.1186/s13041-023-01064-4
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    Methotrexate-based PROTACs as DHFR-specific chemical probes
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      DOI: 10.1016/j.chembiol.2023.09.014

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    sciencedirect.com/science/article/pii/S2451945623003331
  50. www.sciencedirect.com www.sciencedirect.com
    Hepatocytic lipocalin-2 controls HDL metabolism and atherosclerosis via Nedd4-1-SR-BI axis in mice
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    sciencedirect.com/science/article/pii/S153458072300494X
  51. www.sciencedirect.com www.sciencedirect.com
    Lipid accumulation-mediated histone hypoacetylation drives persistent NK cell dysfunction in anti-tumor immunity
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    sciencedirect.com/science/article/pii/S2211124723012238
  52. www.cell.com www.cell.com
    AMER1 deficiency promotes the distant metastasis of colorectal cancer by inhibiting SLC7A11- and FTL-mediated ferroptosis
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    cell.com/cell-reports/abstract/S2211-1247(23)01121-X
  53. Sep 2023
  54. www.sciencedirect.com www.sciencedirect.com
    Chemoproteomic strategy identified p120-catenin glutathionylation regulates E-cadherin degradation and cell migration
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    sciencedirect.com/science/article/abs/pii/S2451945623002763
  55. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    CHIP protects against septic acute kidney injury by inhibiting NLRP3-mediated pyroptosis
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  56. Aug 2023
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  63. May 2023
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  74. Nov 2022
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  76. Oct 2022
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    SPT5 stabilizes RNA polymerase II, orchestrates transcription cycles, and maintains the enhancer landscape
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  114. Aug 2021
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    Elongation Factor TFIIS Prevents Transcription Stress and R-Loop Accumulation to Maintain Genome Stability
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  116. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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    The F-box Protein KIB1 Mediates Brassinosteroid-Induced Inactivation and Degradation of GSK3-like Kinases in Arabidopsis
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    Arginine monomethylation by PRMT7 controls MAVS-mediated antiviral innate immunity
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  121. May 2021
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    The Nuclear SUMO-Targeted Ubiquitin Quality Control Network Regulates the Dynamics of Cytoplasmic Stress Granules
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  125. Apr 2021
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    Convergence of mammalian RQC and C-end rule proteolytic pathways via alanine tailing
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    Proteostasis Regulators Restore Function of Epilepsy-Associated GABAA Receptors
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  128. Feb 2021
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    Acetyl-CoA Synthetase 2: A Critical Linkage in Obesity-Induced Tumorigenesis in Myeloma
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    ALS-causing SOD1 mutants regulate occludin phosphorylation/ubiquitination and endocytic trafficking via the ITCH/Eps15/Rab5 axis
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  132. Nov 2020
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    Unbiased Proteomic Screening Identifies a Novel Role for the E3 Ubiquitin Ligase Nedd4‐2 in Translational Suppression During ER Stress
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    (−)-Epicatechin reduces muscle waste after complete spinal cord transection in a murine model: role of ubiquitin–proteasome system
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  135. Sep 2020
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    Legionella Manipulates Non-canonical SNARE Pairing Using a Bacterial Deubiquitinase
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    Regulation of S100A8 Stability by RNF5 in Intestinal Epithelial Cells Determines Intestinal Inflammation and Severity of Colitis
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    Reducing Hypothalamic Stem Cell Senescence Protects against Aging-Associated Physiological Decline
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  143. Jan 2020
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    Elongation Factor TFIIS Prevents Transcription Stress and R-Loop Accumulation to Maintain Genome Stability
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    Trans-omics Impact of Thymoproteasome in Cortical Thymic Epithelial Cells
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    CircACC1 Regulates Assembly and Activation of AMPK Complex under Metabolic Stress
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    A Systems Pharmacology Approach Uncovers Wogonoside as an Angiogenesis Inhibitor of Triple-Negative Breast Cancer by Targeting Hedgehog Signaling
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    C2‐lacking isoform of Nedd4‐2 regulates excitatory synaptic strength through GluA1 ubiquitination‐independent mechanisms
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    Upregulation of the Autophagy Adaptor p62/SQSTM1 Prolongs Health and Lifespan in Middle-Aged Drosophila
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    Hantavirus Inhibits TRAIL-Mediated Killing of Infected Cells by Downregulating Death Receptor 5
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    VCP Machinery Mediates Autophagic Degradation of Empty Argonaute
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    Regulation of Phosphoribosyl-Linked Serine Ubiquitination by Deubiquitinases DupA and DupB
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    CRISPR/Cas9 Screens Reveal Multiple Layers of B cell CD40 Regulation
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    Processing of DNA Polymerase-Blocking Lesions during Genome Replication Is Spatially and Temporally Segregated from Replication Forks
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    Regulation of the Elongation Phase of Protein Synthesis Enhances Translation Accuracy and Modulates Lifespan
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    Dynamic Acetylation of Phosphoenolpyruvate Carboxykinase Toggles Enzyme Activity between Gluconeogenic and Anaplerotic Reactions
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    Chloroplast Biogenesis Controlled by DELLA-TOC159 Interaction in Early Plant Development
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    BAI1 Suppresses Medulloblastoma Formation by Protecting p53 from Mdm2-Mediated Degradation
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    Disruption of XIAP-RIP2 Association Blocks NOD2-Mediated Inflammatory Signaling
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  166. Nov 2017
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    Defining a Cancer Dependency Map
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    Mechanisms of Ubiquitin-Nucleosome Recognition and Regulation of 53BP1 Chromatin Recruitment by RNF168/169 and RAD18
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    RING finger E3 ligase PPP1R11 regulates TLR2 signaling and innate immunity
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