69 Matching Annotations
  1. Jun 2024
  2. www.sciencedirect.com www.sciencedirect.com
    Sustained generation of neurons destined for neocortex with oxidative metabolic upregulation upon filamin abrogation
    1
    1. scibot 21 Jun 2024
      RRID:AB_331405

      DOI: 10.1016/j.isci.2024.110199

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    sciencedirect.com/science/article/pii/S258900422401424X
  3. May 2024
  4. 52.53.155.43 52.53.155.43
    PIIS2589004224013336-html.html
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    1. scibot 30 May 2024
      RRID:AB_331405

      DOI: 10.1016/j.isci.2024.110108

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    52.53.155.43/201eeea7517d8f69343e1388322eb99416c3ef0f/PIIS2589004224013336-html.html
  5. 52.53.155.43 52.53.155.43
    Phenotype-specific melanoma uptake of fatty acid from human adipocytes activates AXL and CAV1-dependent β-catenin nuclear accumulation
    1
    1. scibot 04 May 2024
      AB_331405

      DOI: 10.1101/2024.01.21.576568

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    52.53.155.43/5631ba0ece03be5b6bc39fba9c8a58e52d07c519/2024.01.21.576568v1.full-html.html
  6. Feb 2024
  7. www.sciencedirect.com www.sciencedirect.com
    Trans-omic analysis reveals opposite metabolic dysregulation between feeding and fasting in liver associated with obesity
    1
    1. scibot 27 Feb 2024
      Cell Signaling Technology#9336

      DOI: 10.1016/j.isci.2024.109121

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    sciencedirect.com/science/article/pii/S2589004224003420
  8. www.sciencedirect.com www.sciencedirect.com
    β1 integrin mediates unresponsiveness to PI3Kα inhibition for radiochemosensitization of 3D HNSCC models
    1
    1. scibot 02 Feb 2024
      RRID:AB_331405

      DOI: 10.1016/j.biopha.2024.116217

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    sciencedirect.com/science/article/pii/S0753332224000982
  9. link.springer.com link.springer.com
    The relevance between abnormally elevated serum ceramide and cognitive impairment in Alzheimer’s disease model mice and its mechanism
    1
    1. scibot 01 Feb 2024
      RRID:AB_331405

      DOI: 10.1007/s00213-024-06530-y

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    link.springer.com/article/10.1007/s00213-024-06530-y
  10. Jan 2024
  11. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Akt activation ameliorates deficits in hippocampal-dependent memory and activity-dependent synaptic protein synthesis in an Alzheimer’s disease mouse model
    1
    1. scibot 06 Jan 2024
      RRID:AB_331405

      DOI: 10.1016/j.jbc.2023.105619

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    ncbi.nlm.nih.gov/pmc/articles/PMC10839450/
  12. Aug 2023
  13. 52.53.155.43 52.53.155.43
    SSRN-id4493933-html.html
    1
    1. scibot 10 Aug 2023
      RRID:AB_331405

      DOI: 10.2139/ssrn.4493933

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    52.53.155.43/08c4dbafd821964dea682c937a91353f8c556b6a/SSRN-id4493933-html.html
  14. Jul 2023
  15. www.sciencedirect.com www.sciencedirect.com
    Tissue factor is a critical regulator of radiation therapy-induced glioblastoma remodeling
    1
    1. scibot 14 Jul 2023
      RRID:AB_331405

      DOI: 10.1016/j.ccell.2023.06.007

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    sciencedirect.com/science/article/pii/S1535610823002179
  16. Jun 2023
  17. www.sciencedirect.com www.sciencedirect.com
    Endogenous PP2A inhibitor CIP2A degradation by chaperone-mediated autophagy contributes to the antitumor effect of mitochondrial complex I inhibition
    1
    1. scibot 09 Jun 2023
      RRID:AB_331405

      DOI: 10.1016/j.celrep.2023.112616

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    sciencedirect.com/science/article/pii/S2211124723006277
  18. academic.oup.com academic.oup.com
    Increased fibrosis in white adipose tissue of male and female bGH transgenic mice appears independent of TGF-β action
    1
    1. scibot 02 Jun 2023
      AB_331405

      DOI: 10.1210/endocr/bqad038

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    academic.oup.com/endo/article/164/5/bqad038/7069260
  19. May 2023
  20. www.sciencedirect.com www.sciencedirect.com
    AKT activation because of PTEN loss upregulates xCT via GSK3β/NRF2, leading to inhibition of ferroptosis in PTEN-mutant tumor cells
    1
    1. scibot 25 May 2023
      RRID:AB_331405

      DOI: 10.1016/j.celrep.2023.112536

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    sciencedirect.com/science/article/pii/S2211124723005478
  21. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    PICK1-Deficient Mice Maintain Their Glucose Tolerance During Diet-Induced Obesity
    1
    1. scibot 18 May 2023
      RRID:AB_331405

      DOI: 10.1210/jendso/bvad057

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    ncbi.nlm.nih.gov/pmc/articles/PMC10185814/
  22. www.nature.com www.nature.com
    Restoration of lysosomal acidification rescues autophagy and metabolic dysfunction in non-alcoholic fatty liver disease
    1
    1. scibot 06 May 2023
      RRID:AB_331405

      DOI: 10.1038/s41467-023-38165-6

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    nature.com/articles/s41467-023-38165-6
  23. Apr 2023
  24. www.nature.com www.nature.com
    Sex difference in evolution of cognitive decline: studies on mouse model and the Dominantly Inherited Alzheimer Network cohort
    1
    1. scibot 18 Apr 2023
      RRID:AB_331405

      DOI: 10.1038/s41398-023-02411-8

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    nature.com/articles/s41398-023-02411-8
  25. Mar 2023
  26. www.sciencedirect.com www.sciencedirect.com
    FAK-mediated phosphorylation at Y464 regulates p85β nuclear translocation to promote tumorigenesis of ccRCC by repressing RB1 expression
    1
    1. scibot 02 Mar 2023
      RRID:AB_331405

      DOI: 10.1016/j.celrep.2023.112188

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    sciencedirect.com/science/article/pii/S2211124723001997
  27. Feb 2023
  28. www.mdpi.com www.mdpi.com
    CXXC5 Mediates DHT-Induced Androgenetic Alopecia via PGD2
    1
    1. scibot 15 Feb 2023
      RRID:AB_331405

      DOI: 10.3390/cells12040555

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    mdpi.com/2073-4409/12/4/555
  29. Jan 2023
  30. www.nature.com www.nature.com
    Hippocampal dentate gyri proteomics reveals Wnt signaling involvement in the behavioral impairment in the THRSP-overexpressing ADHD mouse model
    1
    1. scibot 19 Jan 2023
      RRID:AB_331405

      DOI: 10.1038/s42003-022-04387-5

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    nature.com/articles/s42003-022-04387-5
  31. www.sciencedirect.com www.sciencedirect.com
    SLC7A14 imports GABA to lysosomes and impairs hepatic insulin sensitivity via inhibiting mTORC2
    1
    1. scibot 12 Jan 2023
      RRID:AB_331405

      DOI: 10.1016/j.celrep.2022.111984

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    sciencedirect.com/science/article/pii/S2211124722018885
  32. Dec 2022
  33. www.sciencedirect.com www.sciencedirect.com
    The insulin and IGF signaling pathway sustains breast cancer stem cells by IRS2/PI3K-mediated regulation of MYC
    1
    1. scibot 08 Dec 2022
      RRID:AB_331405

      DOI: 10.1016/j.celrep.2022.111759

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    sciencedirect.com/science/article/pii/S2211124722016424
  34. Nov 2022
  35. www.researchsquare.com www.researchsquare.com
    Home
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    1. scibot 11 Nov 2022
      RRID:AB_331405

      DOI: 10.21203/rs.3.rs-658360/v1

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      RRID:AB_331405

      DOI: 10.21203/rs.3.rs-658360/v1

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      RRID:AB_331405

      DOI: 10.21203/rs.3.rs-658360/v1

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    researchsquare.com/article/rs-2787982/v1
  36. Oct 2022
  37. www.sciencedirect.com www.sciencedirect.com
    TREM2 drives microglia response to amyloid-β via SYK-dependent and -independent pathways
    1
    1. scibot 28 Oct 2022
      RRID:AB_331405

      DOI: 10.1016/j.cell.2022.09.033

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    sciencedirect.com/science/article/pii/S0092867422012521
  38. Sep 2022
  39. www.sciencedirect.com www.sciencedirect.com
    The CX3CL1 intracellular domain exhibits neuroprotection via insulin receptor/ insulin like growth factor receptor signaling
    1
    1. scibot 27 Sep 2022
      RRID:AB_331405

      DOI: 10.1016/j.jbc.2022.102532

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    sciencedirect.com/science/article/pii/S0021925822009759
  40. Aug 2022
  41. www.sciencedirect.com www.sciencedirect.com
    Analysis of neuroendocrine clones in NSCLCs using an immuno-guided laser-capture microdissection-based approach
    1
    1. scibot 23 Aug 2022
      RRID:AB_331405

      DOI: 10.1016/j.crmeth.2022.100271

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    sciencedirect.com/science/article/pii/S2667237522001485
  42. Jul 2022
  43. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Altered amyloid precursor protein, tau-regulatory proteins, neuronal numbers and behaviour, but no tau pathology, synaptic and inflammatory changes or memory deficits, at 1-month following repetitive mild traumatic brain injury
    1
    1. scibot 27 Jul 2022
      AB_331405

      DOI: 10.1111/ejn.15752

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    onlinelibrary.wiley.com/doi/10.1111/ejn.15752
  44. Jun 2022
  45. academic.oup.com academic.oup.com
    Influence of maternal exercise on glucose and lipid metabolism in offspring stem cells: ENHANCED by Mom
    1
    1. scibot 03 Jun 2022
      RRID:AB_331405

      DOI: 10.1210/clinem/dgac270

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    academic.oup.com/jcem/advance-article/doi/10.1210/clinem/dgac270/6577152
  46. May 2022
  47. link.springer.com link.springer.com
    Alzheimer risk gene product Pyk2 suppresses tau phosphorylation and phenotypic effects of tauopathy
    1
    1. scibot 05 May 2022
      RRID:AB_331405

      DOI: 10.1186/s13024-022-00526-y

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    link.springer.com/article/10.1186/s13024-022-00526-y
  48. Feb 2022
  49. www.sciencedirect.com www.sciencedirect.com
    A mouse model of inherited choline kinase β-deficiency presents with specific cardiac abnormalities and a predisposition to arrhythmia
    1
    1. scibot 13 Feb 2022
      Cell signaling, Cat#9336

      DOI: 10.1016/j.jbc.2022.101716

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    sciencedirect.com/science/article/pii/S0021925822001569
  50. Oct 2021
  51. www.sciencedirect.com www.sciencedirect.com
    RNF8-mediated regulation of Akt promotes lung cancer cell survival and resistance to DNA damage
    1
    1. scibot 21 Oct 2021
      RRID:AB_331405

      DOI: 10.1016/j.celrep.2021.109854

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    sciencedirect.com/science/article/pii/S2211124721013218
  52. Sep 2021
  53. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Hepatocyte activity of the cholesterol sensor smoothened regulates cholesterol and bile acid homeostasis in mice
    1
    1. scibot 28 Sep 2021
      RRID:AB_331405

      DOI: 10.1016/j.isci.2021.103089

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    ncbi.nlm.nih.gov/pmc/articles/PMC8449244/
  54. Aug 2021
  55. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Leukemia associated RUNX1T1 gene reduced proliferation and invasiveness of glioblastoma cells
    1
    1. scibot 11 Aug 2021
      9336

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    onlinelibrary.wiley.com/doi/10.1002/jcb.30126
  56. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Untitled document
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    1. scibot 06 Aug 2021
      RRID:AB_331405

      DOI: 10.1111/jnc.14051

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    onlinelibrary.wiley.com/doi/full/10.1111/jnc.14051
  57. www.sciencedirect.com www.sciencedirect.com
    Inhibition of PHLPP1/2 phosphatases rescues pancreatic β-cells in diabetes
    1
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      RRID:AB_331405

      DOI: 10.1016/j.celrep.2021.109490

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    sciencedirect.com/science/article/pii/S2211124721009177
  58. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Pathology of nNOS expressing GABAergic neurons in mouse model of Alzheimer’s disease
    1
    1. scibot 03 Aug 2021
      RRID:AB_331405

      DOI: 10.1016/j.neuroscience.2018.05.013

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    ncbi.nlm.nih.gov/pmc/articles/PMC6085873/
  59. Jul 2021
  60. www.embopress.org www.embopress.org
    CDK12 drives breast tumor initiation and trastuzumab resistance via WNT and IRS1‐ErbB‐PI3K signaling
    1
    1. scibot 30 Jul 2021
      p‐GSK‐3β

      DOI: 10.15252/embr.201948058

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    embopress.org/doi/10.15252/embr.201948058
  61. academic.oup.com academic.oup.com
    Untitled document
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    1. scibot 28 Jul 2021
      RRID:AB_331405

      DOI: 10.1210/en.2018-00899

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    academic.oup.com/endo/article/160/2/377/5235619
  62. link.springer.com link.springer.com
    Untitled document
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    1. scibot 27 Jul 2021
      RRID:AB_331405

      DOI: 10.1007/s12031-018-1199-7

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    link.springer.com/article/10.1007/s12031-018-1199-7
  63. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    KY19382, a novel activator of Wnt/β‐catenin signalling, promotes hair regrowth and hair follicle neogenesis
    1
    1. scibot 14 Jul 2021
      RRID:AB_331405

      DOI: 10.1111/bph.15438

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    ncbi.nlm.nih.gov/pmc/articles/PMC8251890/
  64. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The Ca2+-activated cation channel TRPM4 is a positive regulator of pressure overload-induced cardiac hypertrophy
    1
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      DOI: 10.7554/eLife.66582

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  65. May 2021
  66. www.sciencedirect.com www.sciencedirect.com
    PSD-95 deficiency alters GABAergic inhibition in the prefrontal cortex
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      DOI: 10.1016/j.neuropharm.2020.108277

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  67. www.sciencedirect.com www.sciencedirect.com
    A Non-canonical PDK1-RSK Signal Diminishes Pro-caspase-8-Mediated Necroptosis Blockade
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      DOI: 10.1016/j.molcel.2020.09.004

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  68. www.sciencedirect.com www.sciencedirect.com
    An Oncogenic Alteration Creates a Microenvironment that Promotes Tumor Progression by Conferring a Metabolic Advantage to Regulatory T Cells
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      DOI: 10.1016/j.immuni.2020.06.016

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    sciencedirect.com/science/article/pii/S1074761320302715
  69. Mar 2021
  70. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
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      DOI: 10.1111/bph.15393

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  71. Feb 2021
  72. academic.oup.com academic.oup.com
    Maternal high fat diet multigenerationally impairs hippocampal synaptic plasticity and memory in male rat offspring
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      DOI: 10.1210/endocr/bqaa214

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  73. onlinelibrary.wiley.com onlinelibrary.wiley.com
    MicroRNA‐34a causes ceramide accumulation and effects insulin signaling pathway by targeting ceramide kinase (CERK) in aging skeletal muscle
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  74. Jan 2021
  75. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
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  76. Dec 2020
  77. onlinelibrary.wiley.com onlinelibrary.wiley.com
    The cGMP system in normal and degenerating mouse neuroretina: New proteins with cGMP interaction potential identified by a proteomics approach
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      Rabbit anti‐p‐GSK3β (Ser 9)

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  78. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Intranasal deferoxamine can improve memory in healthy C57 mice, suggesting a partially non‐disease‐specific pathway of functional neurologic improvement
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  79. Sep 2020
  80. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Enhanced Akt/GSK‐3β/CREB signaling mediates the anti‐inflammatory actions of mGluR5 positive allosteric modulators in microglia and following traumatic brain injury in male mice
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  81. faseb.onlinelibrary.wiley.com faseb.onlinelibrary.wiley.com
    β2‐adrenoceptor activation improves skeletal muscle autophagy in neurogenic myopathy
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      DOI: 10.1096/fj.201902305R

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    faseb.onlinelibrary.wiley.com/doi/10.1096/fj.201902305R
  82. www.mdpi.com www.mdpi.com
    IGF-1 Signalling Regulates Mitochondria Dynamics and Turnover through a Conserved GSK-3β–Nrf2–BNIP3 Pathway
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    1. scibot 03 Sep 2020
      rabbit anti-phospho-GSK-3β

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    mdpi.com/2073-4409/9/1/147
  83. Jan 2020
  84. www.sciencedirect.com www.sciencedirect.com
    Discovery of an AKT Degrader with Prolonged Inhibition of Downstream Signaling
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      DOI: 10.1016/j.chembiol.2019.11.014

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    sciencedirect.com/science/article/pii/S2451945619303964
  85. www.sciencedirect.com www.sciencedirect.com
    SFRPs Are Biphasic Modulators of Wnt-Signaling-Elicited Cancer Stem Cell Properties beyond Extracellular Control
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    1. scibot 13 Jan 2020
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      DOI: 10.1016/j.celrep.2019.07.023

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    sciencedirect.com/science/article/pii/S2211124719309131
  86. academic.oup.com academic.oup.com
    Role of hepatic glucocorticoid receptor in metabolism in models of 5αR1 Deficiency in Male Mice
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      RRID:AB_331405

      DOI: 10.1210/en.2019-00236

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    academic.oup.com/endo/article/160/9/2061/5518336
  87. www.sciencedirect.com www.sciencedirect.com
    Untitled document
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      DOI: 10.1016/j.neulet.2018.11.018

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    sciencedirect.com/science/article/pii/S0304394018308048
  88. www.sciencedirect.com www.sciencedirect.com
    Light Entrains Diurnal Changes in Insulin Sensitivity of Skeletal Muscle via Ventromedial Hypothalamic Neurons
    1
    1. scibot 12 Jan 2020
      RRID:AB_331405

      DOI: 10.1016/j.celrep.2019.04.093

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    sciencedirect.com/science/article/pii/S221112471930573X
  89. Nov 2018
  90. www.sciencedirect.com www.sciencedirect.com
    Juvenile treatment with mGluR2/3 agonist prevents schizophrenia-like phenotypes in adult by acting through GSK3β
    1
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    sciencedirect.com/science/article/pii/S0028390818302429
  91. academic.oup.com academic.oup.com
    FGF23 Regulates Wnt/β-Catenin Signaling-Mediated Osteoarthritis in Mice Overexpressing High-Molecular-Weight FGF2
    1
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    academic.oup.com/endo/article/159/6/2386/4985542
  92. www.sciencedirect.com www.sciencedirect.com
    Pathology of nNOS expressing GABAergic neurons in mouse model of Alzheimer’s disease
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    sciencedirect.com/science/article/pii/S0306452218303567
  93. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Lithium Inhibits GSK3β and Augments GluN2A Receptor Expression in the Prefrontal Cortex
    1
    1. scibot 05 Nov 2018
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    ncbi.nlm.nih.gov/pmc/articles/PMC5799274/
  94. www.sciencedirect.com www.sciencedirect.com
    Pharmacological targeting of GSK-3 and NRF2 provides neuroprotection in a preclinical model of tauopathy
    1
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      Cell Signaling#9336

      Curator: @bandrow

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    sciencedirect.com/science/article/pii/S2213231717306687
  95. Nov 2017
  96. www.sciencedirect.com www.sciencedirect.com
    Apolipoprotein E4 Impairs Neuronal Insulin Signaling by Trapping Insulin Receptor in the Endosomes
    1
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      Curator: @Jmenke

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    sciencedirect.com/science/article/pii/S0896627317307912
  97. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Context Specificity in Causal Signaling Networks Revealed by Phosphoprotein Profiling
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    ncbi.nlm.nih.gov/pmc/articles/PMC5279869/
  98. www.nature.com www.nature.com
    ApoE4-associated phospholipid dysregulation contributes to development of Tau hyper-phosphorylation after traumatic brain injury
    1
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      Curator: @kaitlinsung

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    nature.com/articles/s41598-017-11654-7
  99. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Brief isoflurane anesthesia regulates striatal AKT‐GSK3β signaling and ameliorates motor deficits in a rat model of early‐stage Parkinson′s disease
    1
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      AB_331405

      Curator: @chewbeccax

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    onlinelibrary.wiley.com/doi/10.1111/jnc.14066/full
  100. www.jneurosci.org www.jneurosci.org
    TREM2 Promotes Microglial Survival by Activating Wnt/β-Catenin Pathway
    1
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      Curator: @Zeljana_Babic

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  101. www.sciencedirect.com www.sciencedirect.com
    Context Specificity in Causal Signaling Networks Revealed by Phosphoprotein Profiling
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