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Disrupting the interaction between androgen receptor and its coregulator WDR77 delays the growth of treatment-resistant prostate cancer

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1. scibot 11 Sep 2025
  
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  DOI: 10.1016/j.celrep.2025.116235
  
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sciencedirect.com/science/article/pii/S221112472501006X
Jul 2025
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Ce6 derivative photodynamic therapy triggers PANoptosis and enhances antitumor immunity with LAG3 blockade in cutaneous squamous cell carcinoma

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1. scibot 16 Jul 2025
  
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  DOI: 10.1016/j.xcrm.2025.102239
  
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sciencedirect.com/science/article/pii/S266637912500312X
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Stimulating Soluble Guanylyl Cyclase with the Clinical Agonist Riociguat Restrains the Development and Progression of Castration-Resistant Prostate Cancer

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1. scibot 04 Jul 2025
  
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  DOI: 10.1158/0008-5472.CAN-24-0133
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11695179/
Jun 2025
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Macrophages promote tumor growth by phagocytosis-mediated cytokine amplification in Drosophila

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1. scibot 26 Jun 2025
  
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  DOI: 10.1016/j.cub.2025.05.068
  
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PDF-html.html

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1. scibot 18 Jun 2025
  
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  DOI: 10.1016/j.isci.2025.112801
  
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52.53.155.43/0dae8a278297c88adbf334a09a65a2e37332ee1c/PDF-html.html
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Targeted destruction of follicle stimulating hormone receptor-positive cancer cells in vitro and in vivo by a lytic peptide Phor21-FSHβ conjugate

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1. scibot 12 Jun 2025
  
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  DOI: 10.1186/s10020-025-01292-5
  
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link.springer.com/article/10.1186/s10020-025-01292-5
May 2025
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1-s2.0-S258900422500848X-main-html.html

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1. scibot 18 May 2025
  
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  DOI: 10.1016/j.isci.2025.112587
  
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52.53.155.43/87bd08dee360d46e9dcad365f25fd0fff4374980/1-s2.0-S258900422500848X-main-html.html
Apr 2025
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Interleukin-33 (IL-33) promotes DNA damage-resistance in lung cancer

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1. scibot 16 Apr 2025
  
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  DOI: 10.1038/s41419-025-07624-x
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11992107/
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Identification of a TNIK-CDK9 Axis as a Targetable Strategy for Platinum-Resistant Ovarian Cancer

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1. scibot 04 Apr 2025
  
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  DOI: 10.1158/1535-7163.MCT-24-0785
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11962390/
Mar 2025
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Treadmill exercise in combination with acousto-optic and... : Neural Regeneration Research

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1. scibot 06 Mar 2025
  
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  DOI: 10.4103/NRR.NRR-D-23-01681
  
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journals.lww.com/nrronline/fulltext/2025/09000/treadmill_exercise_in_combination_with.31.aspx
Jan 2025
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Single-cell analysis of neoplastic plasma cells identifies myeloma pathobiology mediators and potential targets

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1. scibot 24 Jan 2025
  
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  DOI: 10.1016/j.xcrm.2024.101925
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11866523/
52.53.155.43 52.53.155.43

1-s2.0-S2589004225001245-main-html.html

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1. scibot 23 Jan 2025
  
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  AB_331426
  
  DOI: 10.1016/j.isci.2025.111864
  
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52.53.155.43/b8347d751839197edb20fe1168219b4048f4b01d/1-s2.0-S2589004225001245-main-html.html
Dec 2024
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TRIM47 promotes head and neck squamous cell carcinoma malignant progression by degrading XAF1 through ubiquitination

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1. scibot 17 Dec 2024
  
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  DOI: 10.1016/j.isci.2024.111590
  
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52.53.155.43/7b7ada939293aea749dc77e398309d21af0f7fc4/1-s2.0-S2589004224028177-main-html.html
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Enhancing efficacy of the MEK inhibitor trametinib with paclitaxel in KRAS-mutated colorectal cancer

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1. scibot 13 Dec 2024
  
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  DOI: 10.1177/17588359241303302
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11632859/
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Circular RNAs trigger nonsense-mediated mRNA decay

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1. scibot 12 Dec 2024
  
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  DOI: 10.1016/j.molcel.2024.11.022
  
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sciencedirect.com/science/article/pii/S109727652400947X
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The ribotoxic stress response drives acute inflammation, cell death, and epidermal thickening in UV-irradiated skin in vivo

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1. scibot 02 Dec 2024
  
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  DOI: 10.1016/j.molcel.2024.10.044
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11671030/
Nov 2024
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A PROTAC degrader suppresses oncogenic functions of PTK6 inducing apoptosis of breast cancer cells

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1. scibot 14 Nov 2024
  
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  DOI: 10.1016/j.chembiol.2024.10.008
  
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sciencedirect.com/science/article/pii/S2451945624004434
Oct 2024
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PKMYT1 Is a Marker of Treatment Response and a Therapeutic Target for CDK4/6 Inhibitor-Resistance in ER+ Breast Cancer

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1. scibot 04 Oct 2024
  
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  DOI: 10.1158/1535-7163.MCT-23-0564
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11443213/
Sep 2024
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Untitled document

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1. scibot 25 Sep 2024
  
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  RRID:AB_2160592
  
  DOI: 10.7554/eLife.41378
  
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ncbi.nlm.nih.gov/pmc/articles/PMC6298778/
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Enhancing efficacy of the MEK inhibitor trametinib with paclitaxel in KRAS-mutated colorectal cancer

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1. scibot 15 Sep 2024
  
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  DOI: 10.1101/2024.09.05.611458
  
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biorxiv.org/content/10.1101/2024.09.05.611458v1
Jul 2024
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1-s2.0-S1535610824002319-mmc1-html.html

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1. scibot 25 Jul 2024
  
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  DOI: 10.1016/j.ccell.2024.06.006
  
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52.53.155.43/fa631816ea536ebd5d77bd5edcecb27537053850/1-s2.0-S1535610824002319-mmc1-html.html
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Targeting the mSWI/SNF complex in POU2F-POU2AF transcription factor-driven malignancies

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1. scibot 25 Jul 2024
  
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  DOI: 10.1016/j.ccell.2024.06.006
  
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A highly potent bi-thiazole inhibitor of LOX rewires collagen architecture and enhances chemoresponse in triple-negative breast cancer

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1. scibot 25 Jul 2024
  
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  DOI: 10.1016/j.chembiol.2024.06.012
  
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cell.com/cell-chemical-biology/fulltext/S2451-9456(24)00273-3
May 2024
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Activation of PKR by a short-hairpin RNA

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1. scibot 17 May 2024
  
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  DOI: 10.1101/2024.05.08.592371
  
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biorxiv.org/content/10.1101/2024.05.08.592371v1
Apr 2024
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The role of RASA2 in predicting radioresistance in lung cancer through regulation of p53

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1. scibot 11 Apr 2024
  
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  DOI: 10.21037/tlcr-24-160
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11002505/
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Induction of Viral Mimicry Upon Loss of DHX9 and ADAR1 in Breast Cancer Cells

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1. scibot 10 Apr 2024
  
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  DOI: 10.1158/2767-9764.CRC-23-0488
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10993856/
Mar 2024
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Histone lysine demethylase 4 family proteins maintain the transcriptional program and adrenergic cellular state of MYCN-amplified neuroblastoma

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1. scibot 29 Mar 2024
  
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  DOI: 10.1016/j.xcrm.2024.101468
  
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  DOI: 10.1016/j.xcrm.2024.101468
  
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INX-315, a selective CDK2 inhibitor, induces cell cycle arrest and senescence in solid tumors

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1. scibot 06 Mar 2024
  
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  DOI: 10.1158/2159-8290.CD-23-0954
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10905675/
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Targeting up-regulated cIAP2 in SOX10-deficient drug tolerant melanoma

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1. scibot 06 Mar 2024
  
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  DOI: 10.1158/1535-7163.MCT-23-0025
  
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2. scibot 06 Mar 2024
  
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  DOI: 10.1158/1535-7163.MCT-23-0025
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10527992/
Feb 2024
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cd-23-0954-html.html

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1. scibot 27 Feb 2024
  
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  DOI: 10.1158/2159-8290.cd-23-0954
  
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52.53.155.43/aaf525c30ae01b53e260240fad732783dfb4bbac/cd-23-0954-html.html
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IGFBP3 Promotes Resistance to Olaparib via Modulating EGFR Signaling in Advanced Prostate Cancer

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1. scibot 09 Feb 2024
  
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  DOI: 10.1016/j.isci.2024.108984
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10847745/
Jan 2024
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Bromodomain inhibitor i-BET858 triggers a unique transcriptional response coupled to enhanced DNA damage, cell cycle arrest and apoptosis in high-grade ovarian carcinoma cells

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1. scibot 26 Jan 2024
  
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  AB_331426
  
  DOI: 10.1186/s13148-023-01477-x
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10105475/
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Cholinergic signaling via muscarinic M1 receptor confers resistance to docetaxel in prostate cancer

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1. scibot 23 Jan 2024
  
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  DOI: 10.1016/j.xcrm.2023.101388
  
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Targeting DNA Repair and Survival Signaling in Diffuse Intrinsic Pontine Gliomas to Prevent Tumor Recurrence

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Econazole selectively induces cell death in NF1-homozygous mutant tumor cells

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Inhibition of the serine/threonine kinase BUB1 reverses taxane resistance in prostate cancer

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mct-23-0025 (1)-html.html

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Vincristine Enhances the Efficacy of MEK Inhibitors in Preclinical Models of KRAS-mutant Colorectal Cancer

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Enhanced glutaminolysis drives hypoxia-induced chemoresistance in pancreatic cancer

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Combining MEK and SRC inhibitors for treatment of colorectal cancer demonstrate increased efficacy in vitro but not in vivo

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BET inhibition induces vulnerability to MCL1 targeting through upregulation of fatty acid synthesis pathway in breast cancer

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High-risk neuroblastoma with NF1 loss of function is targetable using SHP2 inhibition

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A myosin chaperone, UNC-45A, is a novel regulator of intestinal epithelial barrier integrity and repair

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DS-7300a, a DNA Topoisomerase I Inhibitor, DXd-based Antibody-Drug Conjugate Targeting B7-H3 Exerts Potent Antitumor Activities in Preclinical Models

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CRAF dimerization with ARAF regulates KRAS-driven tumor growth

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Antibody-drug conjugate efficacy in neuroblastoma - role of payload, resistance mechanisms, target density, and antibody internalization

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Site-specific N-glycosylation of integrin α2 mediates collagen-dependent cell survival

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Human TBK1 deficiency leads to autoinflammation driven by TNF-induced cell death

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Untitled document

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Fendiline Enhances the Cytotoxic Effects of Therapeutic Agents on PDAC Cells by Inhibiting Tumor-Promoting Signaling Events: A Potential Strategy to Combat PDAC

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ERBB3 overexpression due to miR-205 inactivation confers sensitivity to FGF, metabolic activation, and liability to ERBB3 targeting in glioblastoma

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Retinoic acid receptor‐related orphan receptor RORα regulates differentiation and survival of keratinocytes during hypoxia

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A GPC2 antibody-drug conjugate is efficacious against neuroblastoma and small-cell lung cancer via binding a conformational epitope

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NUDT15-mediated hydrolysis limits the efficacy of anti-HCMV drug ganciclovir

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Ectopically expressed olfactory receptors OR51E1 and OR51E2 suppress proliferation and promote cell death in a prostate cancer cell line

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Collagen-rich omentum is a premetastatic niche for integrin α2-mediated peritoneal metastasis

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A Deregulated HOX Gene Axis Confers an Epigenetic Vulnerability in KRAS-Mutant Lung Cancers

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Dysregulated Expression of the Nuclear Exosome Targeting Complex Component Rbm7 in Nonhematopoietic Cells Licenses the Development of Fibrosis

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BIS-INDOLE DERIVED NUCLEAR RECEPTOR 4A1 (NR4A1, Nur77) LIGANDS AS INHIBITORS OF ENDOMETRIOSIS

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Predictive and Pharmacodynamic Biomarkers of Response to the Phosphatidylinositol 3-Kinase Inhibitor Taselisib in Breast Cancer Preclinical Models

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Obatoclax, a Pan-BCL-2 Inhibitor, Downregulates Survivin to Induce Apoptosis in Human Colorectal Carcinoma Cells Via Suppressing WNT/β-catenin Signaling

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Blockade of Oncogenic NOTCH1 with the SERCA Inhibitor CAD204520 in T Cell Acute Lymphoblastic Leukemia

1
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Lineage-Restricted Regulation of SCD and Fatty Acid Saturation by MITF Controls Melanoma Phenotypic Plasticity

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YAP/TAZ Activation Drives Uveal Melanoma Initiation and Progression

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Overcoming Resistance to the THZ Series of Covalent Transcriptional CDK Inhibitors

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Therapeutic Targeting of CDK12/CDK13 in Triple-Negative Breast Cancer

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Untitled document

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  RRID:AB_331426
  
  DOI: 10.1016/j.molcel.2019.01.033
  
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1. scibot 13 Jan 2020
  
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  RRID:AB_331426
  
  DOI: 10.1016/j.molcel.2019.04.009
  
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1. scibot 13 Jan 2020
  
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  RRID:AB_331426
  
  DOI: 10.1016/j.ccell.2019.01.009
  
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1. scibot 13 Jan 2020
  
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  DOI: 10.1016/j.celrep.2019.02.047
  
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sciencedirect.com/science/article/pii/S2211124719302189
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Superior efficacy of cotreatment with BET protein inhibitor and BCL2 or MCL1 inhibitor against AML blast progenitor cells

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1. scibot 13 Jan 2020
  
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  RRID:AB_331426
  
  DOI: 10.1038/s41408-018-0165-5
  
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ncbi.nlm.nih.gov/pmc/articles/PMC6333829/
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1. scibot 12 Jan 2020
  
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  RRID:AB_331426
  
  DOI: 10.1016/j.scr.2019.101390
  
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sciencedirect.com/science/article/pii/S1873506119300200
Apr 2019
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An ShRNA Screen Identifies MEIS1 as a Driver of Malignant Peripheral Nerve Sheath Tumors

1
1. scibot 04 Apr 2019
  
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  AB_331427
  
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Nov 2018
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Pharmacological Induction of RAS-GTP Confers RAF Inhibitor Sensitivity in KRAS Mutant Tumors

1
1. scibot 05 Nov 2018
  
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bmcbiol.biomedcentral.com bmcbiol.biomedcentral.com

VOPP1 promotes breast tumorigenesis by interacting with the tumor suppressor WWOX

1
1. scibot 05 Nov 2018
  
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  RRID:AB_331426
  
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bmcbiol.biomedcentral.com/articles/10.1186/s12915-018-0576-6
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Targeting KRAS Mutant Cancers with a Covalent G12C-Specific Inhibitor

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1. scibot 05 Nov 2018
  
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Genetic and pharmacological inhibition of Cdk1 provides neuroprotection towards ischemic neuronal death

1
1. scibot 05 Nov 2018
  
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  RRID:AB_331426
  
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nature.com/articles/s41420-018-0044-7
Nov 2017
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Identification of GPC2 as an Oncoprotein and Candidate Immunotherapeutic Target in High-Risk Neuroblastoma

1
1. scibot 08 Nov 2017
  
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RasGRP3 Mediates MAPK Pathway Activation in GNAQ Mutant Uveal Melanoma

1
1. scibot 08 Nov 2017
  
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  AB_331426
  
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TP53 exon-6 truncating mutations produce separation of function isoforms with pro-tumorigenic functions

2
1. scibot 08 Nov 2017
  
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  RRID: AB_331426
  
  Curator: @kaitlinsung
  
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2. scibot 08 Nov 2017
  
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  AB_331426
  
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pmc.ncbi.nlm.nih.gov/articles/PMC5092050/

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