Hypothesis

35 Matching Annotations

Dec 2025
www.sciencedirect.com:5037 www.sciencedirect.com:5037

Jub-induced phosphorylation of Warts inhibits its activity and recruitment into biomolecular condensates

1
1. scibot 09 Dec 2025
  
  in Public
  
  RRID:AB_331460
  
  DOI: 10.1016/j.celrep.2025.116647
  
  Resource: (Cell Signaling Technology Cat# 9111, RRID:AB_331460)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_331460
  
  What is this?
  
  RRID:AB_331460
Visit annotations in context

Tags

RRID:AB_331460

Annotators

scibot

URL

sciencedirect.com:5037/science/article/pii/S2211124725014196
Jul 2025
www.sciencedirect.com www.sciencedirect.com

The mitotic ATR-Chk1 pathway promotes CDK1 activity for faithful chromosome segregation

1
1. scibot 24 Jul 2025
  
  in Public
  
  RRID:AB_331460
  
  DOI: 10.1016/j.celrep.2025.116019
  
  Resource: (Cell Signaling Technology Cat# 9111, RRID:AB_331460)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_331460
  
  What is this?
  
  RRID:AB_331460
Visit annotations in context

Tags

RRID:AB_331460

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S2211124725007909
Apr 2025
www.sciencedirect.com www.sciencedirect.com

Evidence of substrate control of Cdk phosphorylation during the budding yeast cell cycle

1
1. scibot 15 Apr 2025
  
  in Public
  
  RRID:AB_331460
  
  DOI: 10.1016/j.celrep.2025.115534
  
  Resource: (Cell Signaling Technology Cat# 9111, RRID:AB_331460)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_331460
  
  What is this?
  
  RRID:AB_331460
Visit annotations in context

Tags

RRID:AB_331460

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S2211124725003055
Mar 2025
www.sciencedirect.com www.sciencedirect.com

Targeting WEE1 kinase as a therapeutic strategy in ATIP3-deficient breast cancers

1
1. scibot 25 Mar 2025
  
  in Public
  
  RRID:AB_331460
  
  DOI: 10.1016/j.canlet.2025.217665
  
  Resource: (Cell Signaling Technology Cat# 9111, RRID:AB_331460)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_331460
  
  What is this?
  
  RRID:AB_331460
Visit annotations in context

Tags

RRID:AB_331460

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S0304383525002319
Feb 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

OTUD6B regulates KIFC1-dependent centrosome clustering and breast cancer cell survival

1
1. scibot 27 Feb 2025
  
  in Public
  
  RRID:AB_331460
  
  DOI: 10.1038/s44319-024-00361-w
  
  Resource: (Cell Signaling Technology Cat# 9111, RRID:AB_331460)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_331460
  
  What is this?
  
  RRID:AB_331460
Visit annotations in context

Tags

RRID:AB_331460

Annotators

scibot

URL

pmc.ncbi.nlm.nih.gov/articles/PMC11850729/
Jan 2025
www.sciencedirect.com www.sciencedirect.com

Revisiting phosphoregulation of Cdc25C during M-phase induction

1
1. scibot 03 Jan 2025
  
  in Public
  
  RRID:AB_331460
  
  DOI: 10.1016/j.isci.2024.111603
  
  Resource: (Cell Signaling Technology Cat# 9111, RRID:AB_331460)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_331460
  
  What is this?
  
  RRID:AB_331460
Visit annotations in context

Tags

RRID:AB_331460

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S258900422402830X
Nov 2024
www.sciencedirect.com www.sciencedirect.com

Acute multi-level response to defective de novo chromatin assembly in S-phase

1
1. scibot 14 Nov 2024
  
  in Public
  
  RRID:AB_331460
  
  DOI: 10.1016/j.molcel.2024.10.023
  
  Resource: (Cell Signaling Technology Cat# 9111, RRID:AB_331460)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_331460
  
  What is this?
  
  RRID:AB_331460
Visit annotations in context

Tags

RRID:AB_331460

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S1097276524008633
Sep 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

GCN2 is a determinant of the response to WEE1 kinase inhibition in small-cell lung cancer

1
1. scibot 25 Sep 2024
  
  in Public
  
  RRID:AB_331460
  
  DOI: 10.1016/j.celrep.2024.114606
  
  Resource: (Cell Signaling Technology Cat# 9111, RRID:AB_331460)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_331460
  
  What is this?
  
  RRID:AB_331460
Visit annotations in context

Tags

RRID:AB_331460

Annotators

scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC11407228/
Jul 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Energy‑stress‑mediated activation of AMPK sensitizes MPS1 kinase inhibition in triple‑negative breast cancer

1
1. scibot 06 Jul 2024
  
  in Public
  
  RRID:AB_331460
  
  DOI: 10.3892/or.2024.8760
  
  Resource: (Cell Signaling Technology Cat# 9111, RRID:AB_331460)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_331460
  
  What is this?
  
  RRID:AB_331460
Visit annotations in context

Tags

RRID:AB_331460

Annotators

scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC11223027/
Feb 2024
www.sciencedirect.com www.sciencedirect.com

Unraveling the interplay between PKA inhibition and Cdk1 activation during oocyte meiotic maturation

1
1. scibot 18 Feb 2024
  
  in Public
  
  RRID:AB_331460
  
  DOI: 10.1016/j.celrep.2024.113782
  
  Resource: (Cell Signaling Technology Cat# 9111, RRID:AB_331460)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_331460
  
  What is this?
  
  RRID:AB_331460
Visit annotations in context

Tags

RRID:AB_331460

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S2211124724001104
Oct 2023
www.cell.com www.cell.com

PUF60 promotes cell cycle and lung cancer progression by regulating alternative splicing of CDC25C

1
1. scibot 06 Oct 2023
  
  in Public
  
  RRID:AB_331460
  
  DOI: 10.1016/j.celrep.2023.113041
  
  Resource: (Cell Signaling Technology Cat# 9111, RRID:AB_331460)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_331460
  
  What is this?
  
  RRID:AB_331460
Visit annotations in context

Tags

RRID:AB_331460

Annotators

scibot

URL

cell.com/cell-reports/fulltext/S2211-1247(23)01052-5
Jan 2023
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Temporal phosphoproteomics reveals WEE1-dependent control of 53BP1 pathway

1
1. scibot 11 Jan 2023
  
  in Public
  
  RRID:AB_331460
  
  DOI: 10.1016/j.isci.2022.105806
  
  Resource: (Cell Signaling Technology Cat# 9111, RRID:AB_331460)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_331460
  
  What is this?
  
  RRID:AB_331460
Visit annotations in context

Tags

RRID:AB_331460

Annotators

scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC9827073/
Oct 2022
www.sciencedirect.com www.sciencedirect.com

A mechanical G2 checkpoint controls epithelial cell division through E-cadherin-mediated regulation of Wee1-Cdk1

1
1. scibot 12 Oct 2022
  
  in Public
  
  RRID:AB_331460
  
  DOI: 10.1016/j.celrep.2022.111475
  
  Resource: (Cell Signaling Technology Cat# 9111, RRID:AB_331460)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_331460
  
  What is this?
  
  RRID:AB_331460
Visit annotations in context

Tags

RRID:AB_331460

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S2211124722013250
May 2022
www.sciencedirect.com www.sciencedirect.com

The oocyte spindle midzone pauses Cdk1 inactivation during fertilization to enable male pronuclear formation and embryo development

1
1. scibot 13 May 2022
  
  in Public
  
  RRID:AB_331460
  
  DOI: 10.1016/j.celrep.2022.110789
  
  Resource: (Cell Signaling Technology Cat# 9111, RRID:AB_331460)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_331460
  
  What is this?
  
  RRID:AB_331460
Visit annotations in context

Tags

RRID:AB_331460

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S2211124722005563
Jan 2022
www.sciencedirect.com www.sciencedirect.com

WEE1 kinase protects the stability of stalled DNA replication forks by limiting CDK2 activity

1
1. scibot 19 Jan 2022
  
  in Public
  
  RRID:AB_331460
  
  DOI: 10.1016/j.celrep.2021.110261
  
  Resource: (Cell Signaling Technology Cat# 9111, RRID:AB_331460)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_331460
  
  What is this?
  
  RRID:AB_331460
Visit annotations in context

Tags

RRID:AB_331460

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S2211124721017733
Dec 2021
www.sciencedirect.com www.sciencedirect.com

CHK1 protects oncogenic KRAS-expressing cells from DNA damage and is a target for pancreatic cancer treatment

1
1. scibot 01 Dec 2021
  
  in Public
  
  RRID:AB_331460
  
  DOI: 10.1016/j.celrep.2021.110060
  
  Resource: (Cell Signaling Technology Cat# 9111, RRID:AB_331460)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_331460
  
  What is this?
  
  RRID:AB_331460
Visit annotations in context

Tags

RRID:AB_331460

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S2211124721015461
Sep 2021
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

CCNE1 copy number is a biomarker for response to combination WEE1-ATR inhibition in ovarian and endometrial cancer models

1
1. scibot 25 Sep 2021
  
  in Public
  
  RRID:AB_331460
  
  DOI: 10.1016/j.xcrm.2021.100394
  
  Resource: (Cell Signaling Technology Cat# 9111, RRID:AB_331460)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_331460
  
  What is this?
  
  RRID:AB_331460
Visit annotations in context

Tags

RRID:AB_331460

Annotators

scibot

URL

pmc.ncbi.nlm.nih.gov/articles/PMC8484689/
Jul 2021
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Untitled document

1
1. scibot 31 Jul 2021
  
  in Public
  
  RRID:AB_331460
  
  DOI: 10.1016/j.cub.2018.09.059
  
  Resource: (Cell Signaling Technology Cat# 9111, RRID:AB_331460)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_331460
  
  What is this?
  
  RRID:AB_331460
Visit annotations in context

Tags

RRID:AB_331460

Annotators

scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC6287978/
pubs.acs.org pubs.acs.org

Differential Sensitivity to CDK2 Inhibition Discriminates the Molecular Mechanisms of CHK1 Inhibitors as Monotherapy or in Combination with the Topoisomerase I Inhibitor SN38

1
1. scibot 28 Jul 2021
  
  in Public
  
  AB_331460
  
  DOI: 10.1021/acsptsci.9b00001
  
  Resource: (Cell Signaling Technology Cat# 9111, RRID:AB_331460)
  
  Curator: @bandrow
  
  SciCrunch record: RRID:AB_331460
  
  What is this?
  
  RRID:AB_331460
Visit annotations in context

Tags

RRID:AB_331460

Annotators

scibot

URL

pubs.acs.org/doi/full/10.1021/acsptsci.9b00001
May 2021
onlinelibrary.wiley.com onlinelibrary.wiley.com

14–3-3γ prevents centrosome duplication by inhibiting NPM1 function

1
1. scibot 20 May 2021
  
  in Public
  
  phospho-CDK1
  
  DOI: 10.1111/gtc.12848
  
  Resource: (Cell Signaling Technology Cat# 9111, RRID:AB_331460)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:AB_331460
  
  What is this?
  
  RRID:AB_331460 RRIDCUR:Missing
Visit annotations in context

Tags

RRIDCUR:Missing

RRID:AB_331460

Annotators

scibot

URL

onlinelibrary.wiley.com/doi/10.1111/gtc.12848
www.sciencedirect.com www.sciencedirect.com

CHK1 Inhibitor Blocks Phosphorylation of FAM122A and Promotes Replication Stress

1
1. scibot 07 May 2021
  
  in Public
  
  RRID:AB_331460
  
  DOI: 10.1016/j.molcel.2020.10.008
  
  Resource: (Cell Signaling Technology Cat# 9111, RRID:AB_331460)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_331460
  
  What is this?
  
  RRID:AB_331460
Visit annotations in context

Tags

RRID:AB_331460

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S1097276520306912
Mar 2021
www.sciencedirect.com www.sciencedirect.com

MMB-FOXM1-driven premature mitosis is required for CHK1 inhibitor sensitivity

1
1. scibot 03 Mar 2021
  
  in Public
  
  RRID:AB_331460
  
  DOI: 10.1016/j.celrep.2021.108808
  
  Resource: (Cell Signaling Technology Cat# 9111, RRID:AB_331460)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:AB_331460
  
  What is this?
  
  RRID:AB_331460 RRIDCUR:Validated
Visit annotations in context

Tags

RRID:AB_331460

RRIDCUR:Validated

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S2211124721001224
Dec 2020
www.sciencedirect.com www.sciencedirect.com

Bistable, Biphasic Regulation of PP2A-B55 Accounts for the Dynamics of Mitotic Substrate Phosphorylation

1
1. scibot 24 Dec 2020
  
  in Public
  
  RRID:AB_331460
  
  DOI: 10.1016/j.cub.2020.11.058
  
  Resource: (Cell Signaling Technology Cat# 9111, RRID:AB_331460)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:AB_331460
  
  What is this?
  
  RRID:AB_331460 RRIDCUR:Validated
Visit annotations in context

Tags

RRID:AB_331460

RRIDCUR:Validated

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S0960982220317711
Sep 2020
www.sciencedirect.com www.sciencedirect.com

The Apparent Requirement for Protein Synthesis during G2 Phase Is due to Checkpoint Activation

1
1. scibot 26 Sep 2020
  
  in Public
  
  RRID:AB_331460
  
  DOI: 10.1016/j.celrep.2020.107901
  
  Resource: (Cell Signaling Technology Cat# 9111, RRID:AB_331460)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:AB_331460
  
  What is this?
  
  RRID:AB_331460 RRIDCUR:Validated
Visit annotations in context

Tags

RRID:AB_331460

RRIDCUR:Validated

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S2211124720308822
www.sciencedirect.com www.sciencedirect.com

Comprehensive Molecular Characterization Identifies Distinct Genomic and Immune Hallmarks of Renal Medullary Carcinoma

1
1. scibot 16 Sep 2020
  
  in Public
  
  RRID:AB_331460
  
  DOI: 10.1016/j.ccell.2020.04.002
  
  Resource: (Cell Signaling Technology Cat# 9111, RRID:AB_331460)
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:AB_331460
  
  What is this?
  
  RRIDCUR:Validated RRID:AB_331460
Visit annotations in context

Tags

RRIDCUR:Validated

RRID:AB_331460

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S1535610820301641
www.sciencedirect.com www.sciencedirect.com

The Hydrophobic Patch Directs Cyclin B to Centrosomes to Promote Global CDK Phosphorylation at Mitosis

1
1. scibot 12 Sep 2020
  
  in Public
  
  RRID:AB_331460
  
  DOI: 10.1016/j.cub.2019.12.053
  
  Resource: (Cell Signaling Technology Cat# 9111, RRID:AB_331460)
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:AB_331460
  
  What is this?
  
  RRID:AB_331460 RRIDCUR:Validated
Visit annotations in context

Tags

RRID:AB_331460

RRIDCUR:Validated

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S0960982219316860
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Differential Sensitivity to CDK2 Inhibition Discriminates the Molecular Mechanisms of CHK1 Inhibitors as Monotherapy or in Combination with the Topoisomerase I Inhibitor SN38

1
1. scibot 04 Sep 2020
  
  in Public
  
  RRID, AB_331460
  
  DOI: 10.1021/acsptsci.9b00001
  
  Resource: (Cell Signaling Technology Cat# 9111, RRID:AB_331460)
  
  Curator: @evieth
  
  SciCrunch record: RRID:AB_331460
  
  What is this?
  
  RRID:AB_331460
Visit annotations in context

Tags

RRID:AB_331460

Annotators

scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC7088890/
Jan 2020
www.sciencedirect.com www.sciencedirect.com

Untitled document

1
1. scibot 12 Jan 2020
  
  in Public
  
  RRID:AB_331460
  
  DOI: 10.1016/j.cub.2018.09.059
  
  Resource: (Cell Signaling Technology Cat# 9111, RRID:AB_331460)
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:AB_331460
  
  What is this?
  
  RRID:AB_331460 RRIDCUR:Validated
Visit annotations in context

Tags

RRID:AB_331460

RRIDCUR:Validated

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S0960982218312843
Nov 2018
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Untitled document

1
1. scibot 05 Nov 2018
  
  in Public
  
  RRID:AB_331460
  
  Resource used:
  
  (Cell Signaling Technology Cat# 9111S, RRID:AB_331460)
  
  SciCrunch record: RRID:AB_331460
  
  Alternate resolvers: SciCrunch xml N2T identifiers.org
  
  What is this?
  
  RRID:AB_331460
Visit annotations in context

Tags

RRID:AB_331460

Annotators

scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC6085539/
www.sciencedirect.com www.sciencedirect.com

Untitled document

1
1. scibot 05 Nov 2018
  
  in Public
  
  RRID:AB_331460
  
  Resource used:
  
  (Cell Signaling Technology Cat# 9111S, RRID:AB_331460)
  
  SciCrunch record: RRID:AB_331460
  
  Alternate resolvers: SciCrunch xml N2T identifiers.org
  
  What is this?
  
  RRID:AB_331460
Visit annotations in context

Tags

RRID:AB_331460

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S235239641830238X
www.nature.com www.nature.com

Genetic and pharmacological inhibition of Cdk1 provides neuroprotection towards ischemic neuronal death

1
1. scibot 05 Nov 2018
  
  in Public
  
  RRID:AB_331460
  
  Curator: @evieth
  
  Resource used:
  
  (Cell Signaling Technology Cat# 9111S, RRID:AB_331460)
  
  SciCrunch record: RRID:AB_331460
  
  Alternate resolvers: SciCrunch xml N2T identifiers.org
  
  What is this?
  
  RRID:AB_331460 RRIDCUR:Validated
Visit annotations in context

Tags

RRID:AB_331460

RRIDCUR:Validated

Annotators

scibot

URL

nature.com/articles/s41420-018-0044-7
Nov 2017
www.sciencedirect.com www.sciencedirect.com

The Atypical Kinase RIOK1 Promotes Tumor Growth and Invasive Behavior

1
1. scibot 08 Nov 2017
  
  in Public
  
  AB_331460
  
  Curator: @chewbeccax
  
  Resource used:
  
  (Cell Signaling Technology Cat# 9111S, RRID:AB_331460)
  
  SciCrunch record: RRID:AB_331460
  
  Alternate resolvers: SciCrunch xml N2T identifiers.org
  
  What is this?
  
  RRID:AB_331460
Visit annotations in context

Tags

RRID:AB_331460

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S2352396417301585
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

CDK Substrate Phosphorylation and Ordering the Cell Cycle

2
1. scibot 08 Nov 2017
  
  in Public
  
  RRID: AB_331460
  
  Curator: @bandrow
  
  Resource used:
  
  (Cell Signaling Technology Cat# 9111S, RRID:AB_331460)
  
  SciCrunch record: RRID:AB_331460
  
  Alternate resolvers: SciCrunch xml N2T identifiers.org
  
  What is this?
  
  RRID:AB_331460
2. scibot 08 Nov 2017
  
  in Public
  
  AB_331460
  
  Resource used:
  
  (Cell Signaling Technology Cat# 9111S, RRID:AB_331460)
  
  SciCrunch record: RRID:AB_331460
  
  Alternate resolvers: SciCrunch xml N2T identifiers.org
  
  What is this?
  
  RRID:AB_331460
Visit annotations in context

Tags

RRID:AB_331460

Annotators

scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC5161751/table/undtbl1/
www.sciencedirect.com www.sciencedirect.com

CDK Substrate Phosphorylation and Ordering the Cell Cycle

1
1. scibot 08 Nov 2017
  
  in Public
  
  AB_331460
  
  Curator: @chewbeccax
  
  Resource used:
  
  (Cell Signaling Technology Cat# 9111S, RRID:AB_331460)
  
  SciCrunch record: RRID:AB_331460
  
  Alternate resolvers: SciCrunch xml N2T identifiers.org
  
  What is this?
  
  RRID:AB_331460 RRIDCUR:Validated
Visit annotations in context

Tags

RRID:AB_331460

RRIDCUR:Validated

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S0092867416316063