83 Matching Annotations
  1. Sep 2024
  2. www.sciencedirect.com www.sciencedirect.com
    Molecular basis of CX-5461-induced DNA damage response in primary vascular smooth muscle cells
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    sciencedirect.com/science/article/pii/S2405844024132586
  3. Aug 2024
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    Redox heterogeneity in mouse embryonic stem cells individualizes cell fate decisions
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    sciencedirect.com/science/article/pii/S1534580724004453
  5. academic.oup.com academic.oup.com
    Loss of RBBP4 results in defective inner cell mass, severe apoptosis, hyperacetylated histones and preimplantation lethality in mice
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    1. scibot 02 Aug 2024
      rabbit anti-TRP53

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    academic.oup.com/biolreprod/article-abstract/103/1/13/5819637
  6. Jul 2024
  7. www.cell.com www.cell.com
    Endogenous p53 inhibitor TIRR dissociates systemic metabolic health from oncogenic activity
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    1. scibot 18 Jul 2024
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    cell.com/cell-reports/fulltext/S2211-1247(24)00665-X
  8. Jun 2024
  9. www.cell.com www.cell.com
    Teriflunomide/leflunomide synergize with chemotherapeutics by decreasing mitochondrial fragmentation via DRP1 in SCLC
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    1. scibot 30 Jun 2024
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    cell.com/iscience/abstract/S2589-0042(24)01357-9
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    The ribotoxic stress response drives UV-mediated cell death
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    sciencedirect.com/science/article/pii/S0092867424005270
  11. Apr 2024
  12. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Metabolic signature and response to glutamine deprivation are independent of p53 status in B cell malignancies
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    1. scibot 29 Apr 2024
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      DOI: 10.1016/j.isci.2024.109640

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    ncbi.nlm.nih.gov/pmc/articles/PMC11053310/
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    Modulating PCGF4 stability is an efficient metastasis-regulatory strategy utilized by distinct subtypes of Cancer-Associated Fibroblasts in intrahepatic cholangiocarcinoma
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    1. scibot 25 Apr 2024
      9284, Cell Signaling Technology

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    sciencedirect.com/science/article/pii/S0002944024001603
  14. rupress.org rupress.org
    DUX4-induced HSATII transcription causes KDM2A/B-PRC1 nuclear foci and impairs DNA damage response
    2
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      DOI: 10.1083/jcb.202303141

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      DOI: 10.1083/jcb.202303141

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    rupress.org/jcb/article/223/5/e202303141/276604/DUX4-induced-HSATII-transcription-causes-KDM2A-B
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    A senescence restriction point acting on chromatin integrates oncogenic signals
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    1. scibot 04 Apr 2024
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    sciencedirect.com/science/article/pii/S2211124724003723
  16. Feb 2024
  17. www.sciencedirect.com www.sciencedirect.com
    A synergistic two-drug therapy specifically targets a DNA repair dysregulation that occurs in p53-deficient colorectal and pancreatic cancers
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    1. scibot 22 Feb 2024
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    sciencedirect.com/science/article/pii/S2666379124000570
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    Alternative polyadenylation determines the functional landscape of inverted Alu repeats
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    1. scibot 06 Feb 2024
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    sciencedirect.com/science/article/pii/S1097276524000091
  19. Dec 2023
  20. www.sciencedirect.com www.sciencedirect.com
    FANCD2-dependent mitotic DNA synthesis relies on PCNA K164 ubiquitination
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    1. scibot 20 Dec 2023
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      DOI: 10.1016/j.celrep.2023.113523

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    sciencedirect.com/science/article/pii/S2211124723015358
  21. Oct 2023
  22. www.sciencedirect.com www.sciencedirect.com
    Breast Cancer Cells are Sensitized by Piperine to Radiotherapy through Estrogen Receptor-α mediated modulation of a Key NHEJ repair protein- DNA-PK
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    1. scibot 13 Oct 2023
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      DOI: 10.1016/j.phymed.2023.155126

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    sciencedirect.com/science/article/pii/S0944711323004865
  23. Sep 2023
  24. www.nature.com www.nature.com
    Low glucose metabolite 3-phosphoglycerate switches PHGDH from serine synthesis to p53 activation to control cell fate
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    1. scibot 22 Sep 2023
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      DOI: 10.1038/s41422-023-00874-4

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    nature.com/articles/s41422-023-00874-4
  25. Jun 2023
  26. www.sciencedirect.com www.sciencedirect.com
    Suppression of TREX1 Deficiency-Induced Cellular Senescence and Interferonopathies by Inhibition of DNA Damage Response
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    1. scibot 27 Jun 2023
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      DOI: 10.1016/j.isci.2023.107090

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    sciencedirect.com/science/article/pii/S2589004223011677
  27. May 2023
  28. www.sciencedirect.com www.sciencedirect.com
    p53-independent tumor suppression by cell-cycle arrest via CREB/ATF transcription factor OASIS
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    1. scibot 13 May 2023
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      DOI: 10.1016/j.celrep.2023.112479

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    sciencedirect.com/science/article/pii/S2211124723004904
  29. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A Mesenchymal Tumor Cell State Confers Increased Dependency on the BCL-XL Anti-apoptotic Protein in Kidney Cancer
    1
    1. scibot 04 May 2023
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      DOI: 10.1158/1078-0432.CCR-22-0669

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    ncbi.nlm.nih.gov/pmc/articles/PMC9633392/
  30. Feb 2023
  31. www.sciencedirect.com www.sciencedirect.com
    Microtubule-associated proteins MAP7 and MAP7D1 promote DNA double-strand break repair in the G1 cell cycle phase
    1
    1. scibot 17 Feb 2023
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      DOI: 10.1016/j.isci.2023.106107

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    sciencedirect.com/science/article/pii/S2589004223001840
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    Clonal hematopoiesis driven by chromosome 1q/MDM4 trisomy defines a canonical route toward leukemia in Fanconi anemia
    1
    1. scibot 03 Feb 2023
      RRID:AB_331464

      DOI: 10.1016/j.stem.2023.01.006

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    sciencedirect.com/science/article/pii/S1934590923000061
  33. Jan 2023
  34. www.sciencedirect.com www.sciencedirect.com
    Cyclin E-induced replicative stress drives p53-dependent whole-genome duplication
    1
    1. scibot 21 Jan 2023
      RRID:AB_331464

      DOI: 10.1016/j.cell.2022.12.036

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    sciencedirect.com/science/article/pii/S0092867422015793
  35. www.sciencedirect.com www.sciencedirect.com
    Loss of epigenetic information as a cause of mammalian aging
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    1. scibot 19 Jan 2023
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      DOI: 10.1016/j.cell.2022.12.027

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    sciencedirect.com/science/article/pii/S0092867422015707
  36. Oct 2022
  37. www.sciencedirect.com www.sciencedirect.com
    Mechanistic insights into cancer drug resistance through optogenetic PI3K signaling hyperactivation
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      DOI: 10.1016/j.chembiol.2022.10.002

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    sciencedirect.com/science/article/pii/S2451945622003567
  38. Aug 2022
  39. www.sciencedirect.com www.sciencedirect.com
    Analysis of neuroendocrine clones in NSCLCs using an immuno-guided laser-capture microdissection-based approach
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      DOI: 10.1016/j.crmeth.2022.100271

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    sciencedirect.com/science/article/pii/S2667237522001485
  40. www.sciencedirect.com www.sciencedirect.com
    Genetic impairment of succinate metabolism disrupts bioenergetic sensing in adrenal neuroendocrine cancer
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    1. scibot 17 Aug 2022
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      DOI: 10.1016/j.celrep.2022.111218

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    sciencedirect.com/science/article/pii/S221112472201035X
  41. Jul 2022
  42. physoc.onlinelibrary.wiley.com physoc.onlinelibrary.wiley.com
    Protein signaling in response to ex vivo dynamic contractions is independent of training status in rat skeletal muscle
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    1. scibot 27 Jul 2022
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      DOI: 10.1113/EP090446

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    physoc.onlinelibrary.wiley.com/doi/10.1113/EP090446
  43. Dec 2021
  44. www.sciencedirect.com www.sciencedirect.com
    Dynamic stem cell selection safeguards the genomic integrity of the epidermis
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    1. scibot 21 Dec 2021
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      DOI: 10.1016/j.devcel.2021.11.018

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    sciencedirect.com/science/article/pii/S1534580721009424
  45. www.sciencedirect.com www.sciencedirect.com
    NEAT1 is essential for metabolic changes that promote breast cancer growth and metastasis
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    1. scibot 08 Dec 2021
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      DOI: 10.1016/j.cmet.2021.11.011

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    sciencedirect.com/science/article/pii/S1550413121005398
  46. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Combined Inhibition of p38MAPK and PIKfyve Synergistically Disrupts Autophagy to Selectively Target Cancer Cells
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      DOI: 10.1158/0008-5472.CAN-20-3371

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    ncbi.nlm.nih.gov/pmc/articles/PMC8178204/
  47. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Central synaptopathy is the most conserved feature of motor circuit pathology across spinal muscular atrophy mouse models
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      DOI: 10.1016/j.isci.2021.103376

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    ncbi.nlm.nih.gov/pmc/articles/PMC8605199/
  48. Nov 2021
  49. www.sciencedirect.com www.sciencedirect.com
    Exercise downregulates HIPK2 and HIPK2 inhibition protects against myocardial infarction
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    sciencedirect.com/science/article/pii/S2352396421005077
  50. Oct 2021
  51. www.sciencedirect.com www.sciencedirect.com
    Shift in MSL1 alternative polyadenylation in response to DNA damage protects cancer cells from chemotherapeutic agent-induced apoptosis
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      DOI: 10.1016/j.celrep.2021.109815

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    sciencedirect.com/science/article/pii/S2211124721012791
  52. Sep 2021
  53. www.sciencedirect.com www.sciencedirect.com
    A hydride transfer complex reprograms NAD metabolism and bypasses senescence
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      DOI: 10.1016/j.molcel.2021.08.028

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    sciencedirect.com/science/article/pii/S109727652100695X
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    Viral targeting of glioblastoma stem cells with patient-specific genetic and post-translational p53 deregulations
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    sciencedirect.com/science/article/pii/S2211124721011177
  55. Aug 2021
  56. www.sciencedirect.com www.sciencedirect.com
    GDF15 mediates the metabolic effects of PPARβ/δ by activating AMPK
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    sciencedirect.com/science/article/pii/S2211124721009293
  57. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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      DOI: 10.1016/j.celrep.2018.12.071

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    ncbi.nlm.nih.gov/pmc/articles/PMC6334229/
  58. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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    ncbi.nlm.nih.gov/pmc/articles/PMC6224607/
  59. onlinelibrary.wiley.com onlinelibrary.wiley.com
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    onlinelibrary.wiley.com/doi/full/10.1002/jcb.27885
  60. europepmc.org europepmc.org
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      DOI: 10.7554/eLife.40856

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    europepmc.org/articles/PMC6292694/
  61. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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  62. Jul 2021
  63. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Effects of the Antifungal Agent Ciclopirox in HPV‐Positive Cancer Cells: Repression of Viral E6/E7 Oncogene Expression and Induction of Senescence and Apoptosis
    1
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      rabbit anti‐phospho (Ser15) p53

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  64. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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  65. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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  67. mcr.aacrjournals.org mcr.aacrjournals.org
    The SIAH1–HIPK2–p53ser46 Damage Response Pathway is Involved in Temozolomide-Induced Glioblastoma Cell Death
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      anti-phospho-p53

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  68. May 2021
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    An anterograde pathway for sensory axon degeneration gated by a cytoplasmic action of the transcriptional regulator P53
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  70. Apr 2021
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    p53 is a central regulator driving neurodegeneration caused by C9orf72 poly(PR)
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  72. Mar 2021
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    Systematic characterization of mutations altering protein degradation in human cancers
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    Small-molecule probe reveals a kinase cascade that links stress signaling to TCF/LEF and Wnt responsiveness
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  75. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
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  76. Feb 2021
  77. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Loss of POLR1D results in embryonic lethality prior to blastocyst formation in mice
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      rabbit anti‐TRP53

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    A P53-Independent DNA Damage Response Suppresses Oncogenic Proliferation and Genome Instability
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    AMPK-mediated phosphorylation on 53BP1 promotes c-NHEJ
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  80. Nov 2020
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    A Broad Response to Intracellular Long-Chain Polyphosphate in Human Cells
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  82. Sep 2020
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    Comprehensive Molecular Characterization Identifies Distinct Genomic and Immune Hallmarks of Renal Medullary Carcinoma
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    Cas12a Base Editors Induce Efficient and Specific Editing with Low DNA Damage Response
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      DOI: 10.1016/j.celrep.2020.107723

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    Tousled-Like Kinases Suppress Innate Immune Signaling Triggered by Alternative Lengthening of Telomeres
    1
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    A P53-Independent DNA Damage Response Suppresses Oncogenic Proliferation and Genome Instability
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  87. Jan 2020
  88. www.sciencedirect.com www.sciencedirect.com
    53BP1 Enforces Distinct Pre- and Post-resection Blocks on Homologous Recombination
    1
    1. scibot 13 Jan 2020
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      DOI: 10.1016/j.molcel.2019.09.024

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    Outcompeting p53-Mutant Cells in the Normal Esophagus by Redox Manipulation
    1
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      DOI: 10.1016/j.stem.2019.06.011

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    The Polycomb Repressor Complex 1 Drives Double-Negative Prostate Cancer Metastasis by Coordinating Stemness and Immune Suppression
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      DOI: 10.1016/j.ccell.2019.06.009

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  91. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Phosphorylation-mediated interactions with TOPBP1 couple 53BP1 and 9-1-1 to control the G1 DNA damage checkpoint
    1
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      RRID:AB_331464

      DOI: 10.7554/eLife.44353

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  92. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Screening the expression of several miRNAs from TaqMan Low Density Array in traumatic brain injury: miR‐219a‐5p regulates neuronal apoptosis by modulating CCNA2 and CACUL1
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    BACH1 Stabilization by Antioxidants Stimulates Lung Cancer Metastasis
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      DOI: 10.1016/j.celrep.2018.12.071

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  97. Nov 2018
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    The Cdkn1aSUPER Mouse as a Tool to Study p53-Mediated Tumor Suppression
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    Liver Cancer Initiation Requires p53 Inhibition by CD44-Enhanced Growth Factor Signaling
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    Targeting the Senescence-Overriding Cooperative Activity of Structurally Unrelated H3K9 Demethylases in Melanoma
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    Phosphatidylinositol-5-Phosphate 4-Kinases Regulate Cellular Lipid Metabolism By Facilitating Autophagy
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  108. Nov 2017
  109. www.sciencedirect.com www.sciencedirect.com
    Ribonucleotide Reductase Requires Subunit Switching in Hypoxia to Maintain DNA Replication
    1
    1. scibot 08 Nov 2017
      Rabbit polyclonal anti-Phospho-p53 (Ser15)Cell SignalingCat# 9284

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  110. www.jneurosci.org www.jneurosci.org
    DNA-PKcs, ATM, and ATR Interplay Maintains Genome Integrity during Neurogenesis
    2
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      AB_331464

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      AB_331464

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      RRID:AB_331464
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    jneurosci.org/content/37/4/893.long
  111. www.sciencedirect.com www.sciencedirect.com
    TRIB3 Promotes APL Progression through Stabilization of the Oncoprotein PML-RARα and Inhibition of p53-Mediated Senescence
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    1. scibot 08 Nov 2017
      AB_331464

      Curator: @gabimpine

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      (Cell Signaling Technology Cat# 9284, RRID:AB_331464)

      SciCrunch record: RRID:AB_331464

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      RRID:AB_331464 RRIDCUR:Validated
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    sciencedirect.com/science/article/pii/S1535610817301617