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19 Matching Annotations

Feb 2026
www.science.org www.science.org

T cell polarization and NFAT activation are stiffness dependent and differentially regulated by the channels PIEZO1 and ORAI1

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1. scibot 03 Feb 2026
  
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  RRID:AB_331600
  
  DOI: 10.1126/scisignal.adt9566
  
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science.org/doi/10.1126/scisignal.adt9566
Aug 2025
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Tumor-resident probiotic Clostridium butyricum improves aPD-1 efficacy in colorectal cancer models by inhibiting IL-6-mediated immunosuppression

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1. scibot 08 Aug 2025
  
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  DOI: 10.1016/j.ccell.2025.07.012
  
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sciencedirect.com/science/article/pii/S1535610825003186
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Glucose-dependent glycosphingolipid biosynthesis fuels CD8+ T cell function and tumor control

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1. scibot 06 Aug 2025
  
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  RRID:AB_331600
  
  DOI: 10.1016/j.cmet.2025.07.006
  
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sciencedirect.com/science/article/pii/S155041312500333X
May 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

JNK1 inhibitors target distal B cell receptor signaling and overcome BTK-inhibitor resistance in CLL

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1. scibot 22 May 2025
  
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  RRID:AB_331600
  
  DOI: 10.1084/jem.20230681
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11586660/
Mar 2025
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T-bet+ CXCR3+ B cells drive hyperreactive B-T cell interactions in multiple sclerosis

1
1. scibot 20 Mar 2025
  
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  DOI: 10.1016/j.xcrm.2025.102027
  
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sciencedirect.com/science/article/pii/S2666379125001004
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Restoration of LAT activity improves CAR T cell sensitivity and persistence in response to antigen-low acute lymphoblastic leukemia

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1. scibot 11 Mar 2025
  
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  RRID:AB_331600
  
  DOI: 10.1016/j.ccell.2025.02.008
  
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sciencedirect.com/science/article/pii/S1535610825000601
Aug 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Soluble Tim-3 serves as a tumor prognostic marker and therapeutic target for CD8+ T cell exhaustion and anti-PD-1 resistance

1
1. scibot 25 Aug 2024
  
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  DOI: 10.1016/j.xcrm.2024.101686
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11384939/
www.cell.com www.cell.com

Calcineurin is an adaptor required for assembly of the TCR signaling complex

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1. scibot 18 Aug 2024
  
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  RRID:AB_331600
  
  DOI: 10.1016/j.celrep.2024.114568
  
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cell.com/cell-reports/fulltext/S2211-1247(24)00897-0
www.mdpi.com www.mdpi.com

Disc Large Homolog 1 Is Critical for Early T Cell Receptor Micro Cluster Formation and Activation in Human T Cells

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1. scibot 02 Aug 2024
  
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  DOI: 10.3390/vaccines9121446
  
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  RRID:AB_331600 RRIDCUR:Missing
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mdpi.com/2076-393X/9/12/1446/htm
May 2024
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Transient hydroxycholesterol treatment restrains TCR signaling to promote long-term immunity

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1. scibot 17 May 2024
  
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  RRID:AB_331600
  
  DOI: 10.1016/j.chembiol.2024.04.005
  
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sciencedirect.com/science/article/pii/S2451945624001673
May 2023
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Cancer-cell-derived fumarate suppresses the anti-tumor capacity of CD8+ T cells in the tumor microenvironment

1
1. scibot 13 May 2023
  
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  RRID:AB_331600
  
  DOI: 10.1016/j.cmet.2023.04.017
  
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sciencedirect.com/science/article/pii/S1550413123001717
Jan 2022
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Regulation of positive and negative selection and TCR signaling during thymic T cell development by capicua

1
1. scibot 07 Jan 2022
  
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  DOI: 10.7554/eLife.71769
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8700290/
Jun 2021
www.nature.com www.nature.com

Transmembrane adaptor protein PAG is a mediator of PD-1 inhibitory signaling in human T cells

1
1. scibot 08 Jun 2021
  
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  2701
  
  DOI: 10.1038/s42003-021-02225-8
  
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  RRIDCUR:Missing RRID:AB_331600
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nature.com/articles/s42003-021-02225-8
May 2021
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Glycolytic ATP fuels phosphoinositide 3-kinase signaling to support effector T helper 17 cell responses

1
1. scibot 12 May 2021
  
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  RRID:AB_331600
  
  DOI: 10.1016/j.immuni.2021.04.008
  
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sciencedirect.com/science/article/pii/S1074761321001709
Sep 2020
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Multiple Signaling Roles of CD3ε and Its Application in CAR-T Cell Therapy

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1. scibot 17 Sep 2020
  
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  DOI: 10.1016/j.cell.2020.07.018
  
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  RRID:AB_331600 RRIDCUR:Validated
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sciencedirect.com/science/article/pii/S0092867420308837
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THEMIS-SHP1 Recruitment by 4-1BB Tunes LCK-Mediated Priming of Chimeric Antigen Receptor-Redirected T Cells

1
1. scibot 16 Sep 2020
  
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  RRID:AB_331600
  
  DOI: 10.1016/j.ccell.2019.12.014
  
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  Curator: @ethanbadger
  
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  RRIDCUR:Validated RRID:AB_331600
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sciencedirect.com/science/article/pii/S1535610819305847
Jan 2020
www.sciencedirect.com www.sciencedirect.com

Dectin-1 Binding to Annexins on Apoptotic Cells Induces Peripheral Immune Tolerance via NADPH Oxidase-2

1
1. scibot 13 Jan 2020
  
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  RRID:AB_331600
  
  DOI: 10.1016/j.celrep.2019.11.086
  
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  Curator: @ethanbadger
  
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  RRID:AB_331600 RRIDCUR:Validated
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sciencedirect.com/science/article/pii/S2211124719315773
Nov 2018
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B Cell Receptor and CD40 Signaling Are Rewired for Synergistic Induction of the c-Myc Transcription Factor in Germinal Center B Cells

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1. scibot 05 Nov 2018
  
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sciencedirect.com/science/article/pii/S1074761318300293
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Interleukin-10 Directly Inhibits CD8+ T Cell Function by Enhancing N-Glycan Branching to Decrease Antigen Sensitivity

1
1. scibot 05 Nov 2018
  
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  Curator: @Jmenke
  
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  RRID:AB_331600 RRIDCUR:Validated
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RRIDCUR:Validated

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sciencedirect.com/science/article/pii/S1074761318300062