193 Matching Annotations
  1. Apr 2024
  2. 52.53.155.43 52.53.155.43
    The activation of LBH-CRYAB signaling promotes cardiac protection against ischemia-reperfusion injury by inhibiting apoptosis and ferroptosis
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    1. scibot 11 Apr 2024
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  3. Mar 2024
  4. www.sciencedirect.com www.sciencedirect.com
    Epithelial-derived interleukin-23 promotes oral mucosal immunopathology
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    1. scibot 21 Mar 2024
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      DOI: 10.1016/j.immuni.2024.02.020

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    sciencedirect.com/science/article/pii/S1074761324000967
  5. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Mutant α-synuclein causes death of human cortical neurons via ERK1/2 and JNK activation
    1
    1. scibot 09 Mar 2024
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      DOI: 10.1186/s13041-024-01086-6

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    ncbi.nlm.nih.gov/pmc/articles/PMC10916047/
  6. www.sciencedirect.com www.sciencedirect.com
    Bactericidal/permeability-increasing protein instructs dendritic cells to elicit Th22 cell response
    2
    1. scibot 08 Mar 2024
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      DOI: 10.1016/j.celrep.2024.113929

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    2. scibot 08 Mar 2024
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      DOI: 10.1016/j.celrep.2024.113929

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    sciencedirect.com/science/article/pii/S2211124724002572
  7. Feb 2024
  8. www.mdpi.com www.mdpi.com
    Lumbricus Extract Prevents LPS-Induced Inflammatory Activation of BV2 Microglia and Glutamate-Induced Hippocampal HT22 Cell Death by Suppressing MAPK/NF-κB/NLRP3 Signaling and Oxidative Stress
    1
    1. scibot 13 Feb 2024
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    mdpi.com/1467-3045/45/12/620
  9. Jan 2024
  10. www.sciencedirect.com www.sciencedirect.com
    MIF modulates p38/ERK phosphorylation via MKP-1 induction in sarcoidosis
    1
    1. scibot 12 Jan 2024
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      DOI: 10.1016/j.isci.2023.108746

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    sciencedirect.com/science/article/pii/S2589004223028237
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    CHCHD4-TRIAP1 regulation of innate immune signaling mediates skeletal muscle adaptation to exercise
    1
    1. scibot 07 Jan 2024
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      DOI: 10.1016/j.celrep.2023.113626

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    sciencedirect.com/science/article/pii/S2211124723016376
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    The phosphodiesterase 2A controls lymphatic junctional maturation via cGMP-dependent notch signaling
    1
    1. scibot 06 Jan 2024
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      DOI: 10.1016/j.devcel.2023.12.002

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    sciencedirect.com/science/article/pii/S1534580723006524
  13. Dec 2023
  14. www.sciencedirect.com www.sciencedirect.com
    A desmosomal cadherin controls multipotent hair follicle stem cell quiescence and orchestrates regeneration through adhesion signaling
    1
    1. scibot 21 Dec 2023
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      DOI: 10.1016/j.isci.2023.108568

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    sciencedirect.com/science/article/pii/S2589004223026457
  15. Oct 2023
  16. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Non-Psychoactive Phytocannabinoids Inhibit Inflammation-Related Changes of Human Coronary Artery Smooth Muscle and Endothelial Cells
    1
    1. scibot 18 Oct 2023
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      DOI: 10.3390/cells12192389

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    ncbi.nlm.nih.gov/pmc/articles/PMC10571842/
  17. link.springer.com link.springer.com
    Systematic in vivo candidate evaluation uncovers therapeutic targets for LMNA dilated cardiomyopathy and risk of Lamin A toxicity
    1
    1. scibot 17 Oct 2023
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      DOI: 10.1186/s12967-023-04542-4

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    link.springer.com/article/10.1186/s12967-023-04542-4
  18. Aug 2023
  19. www.nature.com www.nature.com
    Extracellular Pgk1 interacts neural membrane protein enolase-2 to improve the neurite outgrowth of motor neurons
    2
    1. scibot 17 Aug 2023
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      DOI: 10.1038/s42003-023-05223-0

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      DOI: 10.1038/s42003-023-05223-0

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    nature.com/articles/s42003-023-05223-0
  20. www.sciencedirect.com www.sciencedirect.com
    A peroxiredoxin-P38 MAPK scaffold increases MAPK activity by MAP3K-independent mechanisms
    1
    1. scibot 12 Aug 2023
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      DOI: 10.1016/j.molcel.2023.07.018

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    sciencedirect.com/science/article/pii/S1097276523005610
  21. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    TPL2 kinase activity regulates microglial inflammatory responses and promotes neurodegeneration in tauopathy mice
    1
    1. scibot 12 Aug 2023
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      DOI: 10.7554/eLife.83451

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    ncbi.nlm.nih.gov/pmc/articles/PMC10411973/
  22. www.sciencedirect.com www.sciencedirect.com
    PLEKHS1 drives PI3Ks and remodels pathway homeostasis in PTEN-null prostate
    1
    1. scibot 11 Aug 2023
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      DOI: 10.1016/j.molcel.2023.07.015

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    sciencedirect.com/science/article/pii/S1097276523005580
  23. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Kinase Suppressor of RAS 1 (KSR1) Maintains the Transformed Phenotype of BRAFV600E Mutant Human Melanoma Cells
    1
    1. scibot 01 Aug 2023
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      DOI: 10.3390/ijms241411821

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    ncbi.nlm.nih.gov/pmc/articles/PMC10380721/
  24. Jul 2023
  25. www.sciencedirect.com www.sciencedirect.com
    Targeted removal of macrophage-secreted interleukin-1 receptor antagonist protects against lethal Candida albicans sepsis
    1
    1. scibot 21 Jul 2023
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      DOI: 10.1016/j.immuni.2023.06.023

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    sciencedirect.com/science/article/pii/S1074761323002807
  26. 52.53.155.43 52.53.155.43
    PLEKHS1 drives PI3Ks and remodels pathway homeostasis in PTEN-null prostate
    2
    1. scibot 18 Jul 2023
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      DOI: 10.1101/2023.05.18.541123

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      DOI: 10.1101/2023.05.18.541123

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    52.53.155.43/47cafcf0b0c101b9655865f446b83a64cc86d1a1/2023.05.18.541123v1.full-html.html
  27. www.sciencedirect.com www.sciencedirect.com
    Targeting endometrial inflammation in intrauterine adhesion ameliorates endometrial fibrosis by priming MSCs to secrete C1INH
    1
    1. scibot 07 Jul 2023
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      DOI: 10.1016/j.isci.2023.107201

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    sciencedirect.com/science/article/pii/S2589004223012786
  28. www.sciencedirect.com www.sciencedirect.com
    Macrophage-mediated extracellular matrix remodeling controls host Staphylococcus aureus susceptibility in the skin
    1
    1. scibot 06 Jul 2023
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      DOI: 10.1016/j.immuni.2023.06.006

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    sciencedirect.com/science/article/pii/S1074761323002637
  29. www.sciencedirect.com www.sciencedirect.com
    Levomilnacipran ameliorates lipopolysaccharide-induced depression-like behaviors and suppressed the TLR4/Ras signaling pathway
    1
    1. scibot 06 Jul 2023
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      DOI: 10.1016/j.intimp.2023.110595

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    sciencedirect.com/science/article/pii/S1567576923009207
  30. Jun 2023
  31. www.sciencedirect.com www.sciencedirect.com
    The nucleotide receptor STING translocates to the phagosomes to negatively regulate anti-fungal immunity
    1
    1. scibot 28 Jun 2023
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      DOI: 10.1016/j.immuni.2023.06.002

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    sciencedirect.com/science/article/pii/S1074761323002376
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    Mechanisms of readthrough mitigation reveal principles of GCN1-mediated translational quality control
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    1. scibot 21 Jun 2023
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      DOI: 10.1016/j.cell.2023.05.035

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    sciencedirect.com/science/article/pii/S0092867423005871
  33. May 2023
  34. www.sciencedirect.com www.sciencedirect.com
    VEGFR-3 signaling restrains the neuron-macrophage crosstalk during neurotropic viral infection
    1
    1. scibot 12 May 2023
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      DOI: 10.1016/j.celrep.2023.112489

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    sciencedirect.com/science/article/pii/S2211124723005004
  35. www.mdpi.com www.mdpi.com
    Lysimachiae Herba Inhibits Inflammatory Reactions and Improves Lipopolysaccharide/D-Galactosamine-Induced Hepatic Injury
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    1. scibot 06 May 2023
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      DOI: 10.3390/antiox10091387

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    mdpi.com/2076-3921/10/9/1387/htm
  36. Mar 2023
  37. elifesciences.org elifesciences.org
    Myosin II regulatory light chain phosphorylation and formin availability modulate cytokinesis upon changes in carbohydrate metabolism
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    1. scibot 16 Mar 2023
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      DOI: 10.7554/eLife.83285

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    elifesciences.org/articles/83285
  38. www.sciencedirect.com www.sciencedirect.com
    Cytotoxic CD161−CD8+ TEMRA cells contribute to the pathogenesis of systemic lupus erythematosus
    1
    1. scibot 09 Mar 2023
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      DOI: 10.1016/j.ebiom.2023.104507

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    sciencedirect.com/science/article/pii/S2352396423000725
  39. Feb 2023
  40. www.sciencedirect.com www.sciencedirect.com
    Non-canonical pattern recognition of a pathogen-derived metabolite by a nuclear hormone receptor identifies virulent bacteria in C. elegans
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      DOI: 10.1016/j.immuni.2023.01.027

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    sciencedirect.com/science/article/pii/S1074761323000390
  41. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    SARS-CoV-2 N protein mediates intercellular nucleic acid dispersion, a feature reduced in Omicron
    1
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      DOI: 10.1016/j.isci.2023.105995

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    ncbi.nlm.nih.gov/pmc/articles/PMC9841735/
  42. Jan 2023
  43. www.sciencedirect.com www.sciencedirect.com
    Drosophila Toll-9 is induced by aging and neurodegeneration to modulate stress signaling and its deficiency exacerbates tau-mediated neurodegeneration
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      DOI: 10.1016/j.isci.2023.105968

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    sciencedirect.com/science/article/pii/S2589004223000457
  44. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Perturbation of placental protein glycosylation by endoplasmic reticulum stress promotes maladaptation of maternal hepatic glucose metabolism
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      DOI: 10.1016/j.isci.2022.105911

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  45. 52.53.155.43 52.53.155.43
    SSRN-id4239126-html.html
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      DOI: 10.2139/ssrn.4239126

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  46. aacrjournals.org aacrjournals.org
    Loss of VOPP1 Contributes to BET Inhibitor Acquired Resistance in Non–Small Cell Lung Cancer Cells
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      DOI: 10.1158/1541-7786.MCR-21-1000

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    aacrjournals.org/mcr/article/20/12/1785/710999/Loss-of-VOPP1-Contributes-to-BET-Inhibitor
  47. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    EZH2/hSULF1 axis mediates receptor tyrosine kinase signaling to shape cartilage tumor progression
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      DOI: 10.7554/eLife.79432

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    ncbi.nlm.nih.gov/pmc/articles/PMC9829410/
  48. royalsocietypublishing.org royalsocietypublishing.org
    Carbonic anhydrases in development: morphological observations and gene expression profiling in sea urchin embryos exposed to acetazolamide
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    1. scibot 08 Jan 2023
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      DOI: 10.1098/rsob.220254

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    royalsocietypublishing.org/doi/10.1098/rsob.220254
  49. Dec 2022
  50. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Rickettsial pathogen inhibits tick cell death through tryptophan metabolite mediated activation of p38 MAP kinase
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      DOI: 10.1016/j.isci.2022.105730

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    ncbi.nlm.nih.gov/pmc/articles/PMC9792911/
  51. www.mdpi.com www.mdpi.com
    Neuroprotective and Anti-Neuroinflammatory Properties of Vignae Radiatae Semen in Neuronal HT22 and Microglial BV2 Cell Lines
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      DOI: 10.3390/nu14245265

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    mdpi.com/2072-6643/14/24/5265
  52. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Naringenin, a citrus flavanone, enhances browning and brown adipogenesis: Role of peroxisome proliferator-activated receptor gamma
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  53. Nov 2022
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    An orally active, small-molecule TNF inhibitor that disrupts the homotrimerization interface improves inflammatory arthritis in mice
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  60. Aug 2022
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    Anti-inflammatory effects of neutral lipids, glycolipids, phospholipids from Halocynthia aurantium tunic by suppressing the activation of NF-κB and MAPKs in LPS-stimulated RAW264.7 macrophages
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    Blocking DCIR mitigates colitis and prevents colorectal tumors by enhancing the GM-CSF-STAT5 pathway
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  64. Jul 2022
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    Microtubule associated protein 4 phosphorylation-induced epithelial-to-mesenchymal transition of podocyte leads to proteinuria in diabetic nephropathy
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    Induction of senescence upon loss of the Ash2l core subunit of H3K4 methyltransferase complexes
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    Genome-wide expression and methylation analyses reveal aberrant cell adhesion signaling in tyrosine kinase inhibitor-resistant CML cells
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  68. Jun 2022
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    Progesterone limits the tumor-promoting effects of the beta-subunit of human chorionic gonadotropin via non-nuclear receptors
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    Satellite cell-specific deletion of Cipc alleviates myopathy in mdx mice
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    Undercarboxylated, but not Carboxylated, Osteocalcin suppresses TNF-α induced inflammatory signaling pathway in Myoblast
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  72. May 2022
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    Cannabinoid receptor 1 antagonist genistein attenuates marijuana-induced vascular inflammation
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  74. Apr 2022
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    HO-1 Upregulation by Kaempferol via ROS-Dependent Nrf2-ARE Cascade Attenuates Lipopolysaccharide-Mediated Intercellular Cell Adhesion Molecule-1 Expression in Human Pulmonary Alveolar Epithelial Cells
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  76. Mar 2022
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    Acute inflammation down-regulates alpha-synuclein expression in enteric neurons
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    Viperin triggers ribosome collision-dependent translation inhibition to restrict viral replication
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    Involvement of CCN1 Protein and TLR2/4 Signaling Pathways in Intestinal Epithelial Cells Response to Listeria monocytogenes
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    The ARM repeat domain of hemocyanin interacts with MKK4 to modulate antimicrobial peptides expression
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    Thymocytes trigger self-antigen-controlling pathways in immature medullary thymic epithelial stages
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    A non-bactericidal cathelicidin provides prophylactic efficacy against bacterial infection by driving phagocyte influx
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  84. Feb 2022
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    A FBXO7/EYA2-SCFFBXW7 axis promotes AXL-mediated maintenance of mesenchymal and immune evasion phenotypes of cancer cells
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  86. Jan 2022
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    The Thioredoxin Reductase Inhibitor Auranofin Suppresses Pulmonary Metastasis of Osteosarcoma, But Not Local Progression
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    Glucose-dependent insulinotropic polypeptide inhibits cardiac hypertrophy and fibrosis in diabetic mice via suppression of TGF-β2
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  90. Dec 2021
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    Combined Inhibition of p38MAPK and PIKfyve Synergistically Disrupts Autophagy to Selectively Target Cancer Cells
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  92. Nov 2021
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  95. Oct 2021
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    Therapeutic silencing of SMOC2 prevents kidney function loss in mouse model of chronic kidney disease
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    Anti-Inflammatory and Antimicrobial Volatile Oils: Fennel and Cumin Inhibit Neutrophilic Inflammation via Regulating Calcium and MAPKs
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  99. Sep 2021
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    Negative charge in the RACK1 loop broadens the translational capacity of the human ribosome
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  101. Aug 2021
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    Transmembrane G protein-coupled receptor 5 signaling stimulates fibroblast growth factor 21 expression concomitant with up-regulation of the transcription factor nuclear receptor Nr4a1
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    Tribbles pseudokinase NIPI-3 regulates intestinal immunity in Caenorhabditis elegans by controlling SKN-1/Nrf activity
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    Entosis is induced by UV radiation.
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  106. academic.oup.com academic.oup.com
    Melatonin inhibits osteoclastogenesis and bone loss in ovariectomized mice by regulating PRMT1-mediated signaling
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      DOI: 10.1210/endocr/bqab057

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  107. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    MAP4K4 Inhibition Promotes Survival of Human Stem Cell-Derived Cardiomyocytes and Reduces Infarct Size In Vivo
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  108. elifesciences.org elifesciences.org
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  109. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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  110. www.sciencedirect.com www.sciencedirect.com
    FBF1 deficiency promotes beiging and healthy expansion of white adipose tissue
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    O-GlcNAc Transferase Links Glucose Metabolism to MAVS-Mediated Antiviral Innate Immunity
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  112. Jul 2021
  113. www.jneurosci.org www.jneurosci.org
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  114. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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  115. www.sciencedirect.com www.sciencedirect.com
    Amino alkynylisoquinoline and alkynylnaphthyridine compounds potently inhibit acute myeloid leukemia proliferation in mice
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  116. journals.sagepub.com journals.sagepub.com
    ANGPTL2 Promotes Inflammation via Integrin α5β1 in Chondrocytes - Mami Takano, Naoto Hirose, Chikako Sumi, Makoto Yanoshita, Sayuri Nishiyama, Azusa Onishi, Yuki Asakawa, Kotaro Tanimoto,
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      Anti–phosphorylated p-38

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    Histone Variant and Cell Context Determine H3K27M Reprogramming of the Enhancer Landscape and Oncogenic State
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      Rabbit polyclonal anti-phospho-p38 MAPK

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  118. elifesciences.org elifesciences.org
    Regulator of G protein signaling 12 enhances osteoclastogenesis by suppressing Nrf2-dependent antioxidant proteins to promote the generation of reactive oxygen species
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      Phospho-p38 (Thr180/Tyr182), rabbit polyclonal

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    Microbially Produced Imidazole Propionate Impairs Insulin Signaling through mTORC1
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  120. www.nature.com www.nature.com
    Exogenous C-type natriuretic peptide therapy for impaired skeletal growth in a murine model of glucocorticoid treatment
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      Phospho-p38

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  121. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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  122. www.sciencedirect.com www.sciencedirect.com
    PEP-1-glutaredoxin-1 induces dedifferentiation of rabbit articular chondrocytes by the endoplasmic reticulum stress-dependent ERK-1/2 pathway and the endoplasmic reticulum stress-independent p38 kinase and PI-3 kinase pathways
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      RRID:AB_331640

      DOI: 10.1016/j.ijbiomac.2018.01.127

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  123. www.sciencedirect.com www.sciencedirect.com
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  124. www.sciencedirect.com www.sciencedirect.com
    Cytokine-induced apoptosis inhibitor-1 causes dedifferentiation of rabbit articular chondrocytes via the ERK-1/2 and p38 kinase pathways
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      AB_331640

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  125. elifesciences.org elifesciences.org
    The PERK arm of the unfolded protein response regulates satellite cell-mediated skeletal muscle regeneration
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  126. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Spinal interleukin-1β induces mechanical spinal hyperexcitability in rats: interactions and redundancies with TNF and IL-6
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  127. Jun 2021
  128. academic.oup.com academic.oup.com
    CX3CL1–CX3CR1 signalling deficiency exacerbates obesity-induced inflammation and insulin resistance in male mice
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      DOI: 10.1210/endocr/bqab064

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  129. www.hindawi.com www.hindawi.com
    Table 2 | Saussureae Radix Attenuates Neuroinflammation in LPS-Stimulated Mouse BV2 Microglia via HO-1/Nrf-2 Induction and Inflammatory Pathway Inhibition
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  130. www.sciencedirect.com www.sciencedirect.com
    Riok3 inhibits the antiviral immune response by facilitating TRIM40-mediated RIG-I and MDA5 degradation
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  131. www.frontiersin.org www.frontiersin.org
    RAGE Differentially Altered in vitro Responses in Vascular Smooth Muscle Cells and Adventitial Fibroblasts in Diabetes-Induced Vascular Calcification
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      DOI: 10.3389/fphys.2021.676727

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    Protective effects of Da-cheng-qi decoction in rats with intracerebral hemorrhage
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    A PGE2-MEF2A axis enables context-dependent control of inflammatory gene expression
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    Metformin inhibition of mitochondrial ATP and DNA synthesis abrogates NLRP3 inflammasome activation and pulmonary inflammation
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    Bacterial genotoxins induce T cell senescence
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  136. May 2021
  137. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    hTERT-immortalized gingival fibroblasts respond to cytokines but fail to mimic primary cell responses to Porphyromonas gingivalis
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      #9211

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  138. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Cyclooxygenase inhibition attenuates brain angiogenesis and independently decreases mouse survival under hypoxia
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  139. journals.physiology.org journals.physiology.org
    Levels of β-klotho determine the thermogenic responsiveness of adipose tissues: involvement of the autocrine action of FGF21
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    Combined inhibition of histone deacetylases and BET family proteins as epigenetic therapy for nerve injury-induced neuropathic pain
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    Proline Hydroxylation Primes Protein Kinases for Autophosphorylation and Activation
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  142. www.sciencedirect.com www.sciencedirect.com
    mTOR signaling regulates gastric epithelial progenitor homeostasis and gastric tumorigenesis via MEK1-ERKs and BMP-Smad1 pathways
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  143. Apr 2021
  144. www.sciencedirect.com www.sciencedirect.com
    Mitochondria Define Intestinal Stem Cell Differentiation Downstream of a FOXO/Notch Axis
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  145. www.sciencedirect.com www.sciencedirect.com
    Ribosome Collisions Trigger General Stress Responses to Regulate Cell Fate
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  146. www.sciencedirect.com www.sciencedirect.com
    Topoisomerase IIα represses transcription by enforcing promoter-proximal pausing
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  147. Mar 2021
  148. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Identification of novel myelin repair drugs by modulation of oligodendroglial differentiation competence
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      RRID:AB_331

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  149. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    BPS Publications
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      RRID:AB_331614

      DOI: 10.1111/bph.15277

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  150. Feb 2021
  151. pubs.acs.org pubs.acs.org
    Hormetic Effects of Binaphthyl Phosphonothioates as Pro-oxidants and Antioxidants
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    NF-κB/Cartilage Acidic Protein 1 Promotes Ultraviolet B Irradiation-Induced Apoptosis of Human Lens Epithelial Cells
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    Lysophosphatidic acid induces thrombospondin‐1 production in primary cultured rat cortical astrocytes
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    Cdc42 is involved in NC1 peptide–regulated BTB dynamics through actin and microtubule cytoskeletal reorganization
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    Extracellular Pgk1 enhances neurite outgrowth of motoneurons through Nogo66/NgR-independent targeting of NogoA
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    Microglial TNFα Induces COX2 and PGI2 Synthase Expression in Spinal Endothelial Cells during Neuropathic Pain
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