251 Matching Annotations
  1. Aug 2025
  2. 52.53.155.43 52.53.155.43
    dhar-et-al-programmed-cell-revival-from-imminent-cell-death-enhances-tissue-repair-and-regeneration-html.html
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    Nitroxoline upregulates low-density lipoprotein receptors expression, enhances lipid metabolism, and reduces hepatic steatosis and atherosclerosis in Apoe−/− mice
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    sciencedirect.com/science/article/pii/S0925443925003643
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    MAVS phosphorylation acts as a cellular stress sensor that modulates antiviral immunity
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    sciencedirect.com/science/article/pii/S2589004225015172
  5. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Scavenger Receptor CD36 in Tumor-Associated Macrophages Promotes Cancer Progression by Dampening Type I Interferon Signaling
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    pmc.ncbi.nlm.nih.gov/articles/PMC11788022/
  6. Jul 2025
  7. www.cell.com www.cell.com
    TBK1 phagosomal recruitment enhances antifungal immunity via positive feedback regulation with SRC
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    cell.com/cell-reports/abstract/S2211-1247(25)00743-0
  8. Jun 2025
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    VCPIP1 potentiates innate immune responses by non-catalytically reducing the ubiquitination of IRAK1/2
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    sciencedirect.com/science/article/pii/S2211124725007028
  10. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Distinct cAMP Regulation in Scleroderma Lung and Skin Myofibroblasts Governs Their Dedifferentiation via p38α Inhibition
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    pmc.ncbi.nlm.nih.gov/articles/PMC12186599/
  11. www.liebertpub.com www.liebertpub.com
    E3 Ubiquitin Ligase Constitutive Photomorphogenic 1 Regulates Differentiation and Inflammation via MAPK Signaling Pathway in Rabbit Articular Chondrocytes
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    liebertpub.com/doi/10.1089/dna.2022.0664
  12. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Mechanistic Understanding of Dexamethasone-Mediated Protection against Remdesivir-Induced Hepatotoxicity
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    pmc.ncbi.nlm.nih.gov/articles/PMC12164689/
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    Piezo1 senses hyphae and initiates host defense against pathogenic fungi
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    sciencedirect.com/science/article/pii/S2211124725006102
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    Cancer selective cell death induction by a bivalent CK2 inhibitor targeting the ATP site and the allosteric αD pocket
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    sciencedirect.com/science/article/pii/S258900422400124X
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    RNA polymerase II subunit 5-mediating protein limits TLR4-induced innate immune activation in macrophages by inhibiting IKKβ/NF-κB signaling during sepsis
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    link.springer.com/article/10.1186/s12964-025-02278-w
  16. May 2025
  17. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Inhibition of IRE1α Alleviates Renal Fibrosis and Downregulates M1 Macrophage Activation via the p38 MAPK Pathway
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    onlinelibrary.wiley.com/doi/10.1111/imm.13949
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    GADD45G operates as a pathological sensor orchestrating reactive gliosis and neurodegeneration
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    sciencedirect.com/science/article/pii/S0896627325003459
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    CDK4/6 activity is required during G2 arrest to prevent stress induced endoreplication
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    pmc.ncbi.nlm.nih.gov/articles/PMC11305671/
  20. Apr 2025
  21. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Integrated pharmacoanalysis, bioinformatics analysis, and experimental validation to identify the ingredients and mechanisms of Xiao-Luo-Wan in uterine fibroids treatment
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    pmc.ncbi.nlm.nih.gov/articles/PMC11999358/
  22. Mar 2025
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    Lipid-metabolism-focused CRISPR screens identify enzymes of the mevalonate pathway as essential for prostate cancer growth
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    sciencedirect.com/science/article/pii/S2211124725002414
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    ENKD1 modulates innate immune responses through enhanced geranylgeranyl pyrophosphate synthase activity
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    sciencedirect.com/science/article/pii/S2211124725001688
  25. Feb 2025
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    Restraint of inflammasome-driven cytokine responses through the mRNA stability protein TTP
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    sciencedirect.com/science/article/pii/S2211124725001111
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    MerTK Induces Dysfunctional Dendritic Cells by Metabolic Reprogramming
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    aacrjournals.org/cancerimmunolres/article/12/9/1268/747083/MerTK-Induces-Dysfunctional-Dendritic-Cells-by
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    Taste receptor type 1 member 3 in osteoclasts regulates osteoclastogenesis via detection of glucose
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    Cellular deconstruction of the human skeletal muscle microenvironment identifies an exercise-induced histaminergic crosstalk
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    SLFN11-mediated ribosome biogenesis impairment induces TP53-independent apoptosis
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  31. Jan 2025
  32. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Anandamide Inhibits Vascular Smooth Muscle Migration, Endothelial Adhesion Protein Expression and Monocyte Adhesion of Human Coronary Artery Cells
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  33. 52.53.155.43 52.53.155.43
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    Non-cell-autonomous regulation of mTORC2 by Hedgehog signaling maintains lipid homeostasis
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    Revisiting phosphoregulation of Cdc25C during M-phase induction
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    The blue-light receptor CRY1 serves as a switch to balance photosynthesis and plant defense
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    Neutrophil extracellular traps promote pre-metastatic niche formation in the omentum by expanding innate-like B cells that express IL-10
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  38. Dec 2024
  39. aacrjournals.org aacrjournals.org
    Nuclear Focal Adhesion Kinase Protects Against Cisplatin Stress in Ovarian Carcinoma
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    Temperature perception by ER UPR promotes preventive innate immunity and longevity
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    Persistence of spike protein at the skull-meninges-brain axis may contribute to the neurological sequelae of COVID-19
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  43. Nov 2024
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    A p38 MAPK-ROS axis fuels proliferation stress and DNA damage during CRISPR-Cas9 gene editing in hematopoietic stem and progenitor cells
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    Lysosomal damage triggers a p38 MAPK-dependent phosphorylation cascade to promote lysophagy via the small heat shock protein HSP27
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  46. Oct 2024
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    Multi-omic human pancreatic islet endoplasmic reticulum and cytokine stress response mapping provides type 2 diabetes genetic insights
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  48. Sep 2024
  49. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    IKKɛ induces STING non-IFN immune responses via a mechanism analogous to TBK1
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    ncbi.nlm.nih.gov/pmc/articles/PMC11387596/
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    Lysosome-related organelle integrity suppresses TIR-1 aggregation to restrain toxic propagation of p38 innate immunity
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    Intestinal immunity in C. elegans is activated by pathogen effector-triggered aggregation of the guard protein TIR-1 on lysosome-related organelles
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  53. Aug 2024
  54. www.sciencedirect.com www.sciencedirect.com
    Histone chaperone HIRA, promyelocytic leukemia protein, and p62/SQSTM1 coordinate to regulate inflammation during cell senescence
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    Defective endomembrane dynamics in Rab27a deficiency impairs nucleic acid sensing and cytokine secretion in immune cells
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    sciencedirect.com/science/article/pii/S2211124724009379
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    Integrative plasma and fecal metabolomics identify functional metabolites in adenoma-colorectal cancer progression and as early diagnostic biomarkers
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  57. 52.53.155.43 52.53.155.43
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  58. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Purinergic receptor P2Y6 contributes to 1‐methyl‐4‐phenylpyridinium‐induced oxidative stress and cell death in neuronal SH‐SY5Y cells
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    onlinelibrary.wiley.com/doi/10.1002/jnr.24119/full
  59. Jul 2024
  60. 52.53.155.43 52.53.155.43
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  61. www.embopress.org www.embopress.org
    Reactive oxygen species activate the Drosophila TNF receptor Wengen for damage-induced regeneration
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    embopress.org/doi/10.1038/s44318-024-00155-9
  62. dx.doi.org dx.doi.org
    Cenicriviroc Suppresses and Reverses Steatohepatitis by Regulating Macrophage Infiltration and M2 Polarization in Mice
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    dx.doi.org/10.1210/endocr/bqae069
  63. 52.53.155.43 52.53.155.43
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  64. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Energy‑stress‑mediated activation of AMPK sensitizes MPS1 kinase inhibition in triple‑negative breast cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC11223027/
  65. Jun 2024
  66. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    p38 MAPK activation and STIM1-Orai3 association mediate TRPC6 externalization
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    ncbi.nlm.nih.gov/pmc/articles/PMC10228675/
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    The ribotoxic stress response drives UV-mediated cell death
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    Endonucleolytic RNA cleavage drives changes in gene expression during the innate immune response
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  69. May 2024
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    The RIPK1 death domain restrains ZBP1- and TRIF-mediated cell death and inflammation
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  71. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Ganoderma lucidum extract attenuates corticotropin-releasing hormone induced cellular senescence in human hair follicle cells
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    ncbi.nlm.nih.gov/pmc/articles/PMC11068553/
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    A 5:2 intermittent fasting regimen ameliorates NASH and fibrosis and blunts HCC development via hepatic PPARα and PCK1
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  73. www.science.org www.science.org
    CDK4/6 activity is required during G2 arrest to prevent stress-induced endoreplication
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    science.org/doi/10.1126/science.adi2421
  74. Apr 2024
  75. 52.53.155.43 52.53.155.43
    The activation of LBH-CRYAB signaling promotes cardiac protection against ischemia-reperfusion injury by inhibiting apoptosis and ferroptosis
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  76. Mar 2024
  77. www.sciencedirect.com www.sciencedirect.com
    Epithelial-derived interleukin-23 promotes oral mucosal immunopathology
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  78. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Mutant α-synuclein causes death of human cortical neurons via ERK1/2 and JNK activation
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    ncbi.nlm.nih.gov/pmc/articles/PMC10916047/
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    Bactericidal/permeability-increasing protein instructs dendritic cells to elicit Th22 cell response
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  80. Feb 2024
  81. www.mdpi.com www.mdpi.com
    Lumbricus Extract Prevents LPS-Induced Inflammatory Activation of BV2 Microglia and Glutamate-Induced Hippocampal HT22 Cell Death by Suppressing MAPK/NF-κB/NLRP3 Signaling and Oxidative Stress
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    mdpi.com/1467-3045/45/12/620
  82. Jan 2024
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    MIF modulates p38/ERK phosphorylation via MKP-1 induction in sarcoidosis
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    CHCHD4-TRIAP1 regulation of innate immune signaling mediates skeletal muscle adaptation to exercise
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    sciencedirect.com/science/article/pii/S2211124723016376
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    The phosphodiesterase 2A controls lymphatic junctional maturation via cGMP-dependent notch signaling
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  86. Dec 2023
  87. www.sciencedirect.com www.sciencedirect.com
    A desmosomal cadherin controls multipotent hair follicle stem cell quiescence and orchestrates regeneration through adhesion signaling
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  88. Oct 2023
  89. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Non-Psychoactive Phytocannabinoids Inhibit Inflammation-Related Changes of Human Coronary Artery Smooth Muscle and Endothelial Cells
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    ncbi.nlm.nih.gov/pmc/articles/PMC10571842/
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    Systematic in vivo candidate evaluation uncovers therapeutic targets for LMNA dilated cardiomyopathy and risk of Lamin A toxicity
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    ncbi.nlm.nih.gov/pmc/articles/PMC10577912/
  91. Aug 2023
  92. www.nature.com www.nature.com
    Extracellular Pgk1 interacts neural membrane protein enolase-2 to improve the neurite outgrowth of motor neurons
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    nature.com/articles/s42003-023-05223-0
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    A peroxiredoxin-P38 MAPK scaffold increases MAPK activity by MAP3K-independent mechanisms
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    TPL2 kinase activity regulates microglial inflammatory responses and promotes neurodegeneration in tauopathy mice
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    PLEKHS1 drives PI3Ks and remodels pathway homeostasis in PTEN-null prostate
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  96. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Kinase Suppressor of RAS 1 (KSR1) Maintains the Transformed Phenotype of BRAFV600E Mutant Human Melanoma Cells
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    ncbi.nlm.nih.gov/pmc/articles/PMC10380721/
  97. Jul 2023
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    Targeted removal of macrophage-secreted interleukin-1 receptor antagonist protects against lethal Candida albicans sepsis
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    PLEKHS1 drives PI3Ks and remodels pathway homeostasis in PTEN-null prostate
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    Targeting endometrial inflammation in intrauterine adhesion ameliorates endometrial fibrosis by priming MSCs to secrete C1INH
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    Macrophage-mediated extracellular matrix remodeling controls host Staphylococcus aureus susceptibility in the skin
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    Levomilnacipran ameliorates lipopolysaccharide-induced depression-like behaviors and suppressed the TLR4/Ras signaling pathway
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  103. Jun 2023
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    The nucleotide receptor STING translocates to the phagosomes to negatively regulate anti-fungal immunity
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    Mechanisms of readthrough mitigation reveal principles of GCN1-mediated translational quality control
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  106. May 2023
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    VEGFR-3 signaling restrains the neuron-macrophage crosstalk during neurotropic viral infection
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