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  1. Sep 2024
  2. www.sciencedirect.com www.sciencedirect.com
    A bispecific antibody targeting EGFR and AXL delays resistance to osimertinib
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    1. scibot 04 Sep 2024
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    sciencedirect.com/science/article/pii/S2666379124004245
  3. Jul 2024
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    Impact of Interleukin-6 Activation and Arthritis on Epidermal Growth Factor Receptor (EGFR) Activation in Sensory Neurons and the Spinal Cord
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      RRID:AB_331701

      DOI: 10.3390/ijms25137168

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    mdpi.com/1422-0067/25/13/7168
  5. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Cbl and Cbl-b ubiquitin ligases are essential for intestinal epithelial stem cell maintenance
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC11225835/
  6. Jun 2024
  7. www.cell.com www.cell.com
    Oxygen tension-dependent variability in the cancer cell kinome impacts signaling pathways and response to targeted therapies
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    cell.com/iscience/abstract/S2589-0042(24)01293-8
  8. May 2024
  9. aacrjournals.org aacrjournals.org
    Discovery of a novel potent EGFR inhibitor against EGFR activating mutations and on-target resistance in NSCLC
    2
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    aacrjournals.org/clincancerres/article/30/8/1582/742134/Discovery-of-a-Novel-Potent-EGFR-Inhibitor-Against
  10. Apr 2024
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    A p85 isoform switch enhances PI3K activation on endosomes by a MAP4- and PI3P-dependent mechanism
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    sciencedirect.com/science/article/pii/S2211124724004479
  12. Mar 2024
  13. www.sciencedirect.com www.sciencedirect.com
    Cellular senescence is associated with the spatial evolution toward a higher metastatic phenotype in colorectal cancer
    2
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    sciencedirect.com/science/article/pii/S2211124724002407
  14. Feb 2024
  15. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Functional Heterogeneity in MET Pathway Activation in PDX Models of Osimertinib Resistant EGFR-Driven Lung Cancer
    1
    1. scibot 11 Feb 2024
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    ncbi.nlm.nih.gov/pmc/articles/PMC10851855/
  16. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    IGFBP3 Promotes Resistance to Olaparib via Modulating EGFR Signaling in Advanced Prostate Cancer
    1
    1. scibot 09 Feb 2024
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    ncbi.nlm.nih.gov/pmc/articles/PMC10847745/
  17. Jan 2024
  18. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Targeting DNA Repair and Survival Signaling in Diffuse Intrinsic Pontine Gliomas to Prevent Tumor Recurrence
    1
    1. scibot 05 Jan 2024
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  19. Aug 2023
  20. 52.53.155.43 52.53.155.43
    L858R emerges as a potential biomarker predicting response of lung cancer models to anti-EGFR antibodies: Comparison of osimertinib vs. cetuximab
    2
    1. scibot 18 Aug 2023
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    2. scibot 10 Aug 2023
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      DOI: 10.1016/j.xcrm.2023.101142

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  21. Jun 2023
  22. aacrjournals.org aacrjournals.org
    RBM10 loss promotes EGFR-driven lung cancer and confers sensitivity to spliceosome inhibition
    1
    1. scibot 03 Jun 2023
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      DOI: 10.1158/0008-5472.CAN-22-1549

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    aacrjournals.org/cancerres/article/83/9/1490/726058/RBM10-Loss-Promotes-EGFR-Driven-Lung-Cancer-and
  23. Apr 2023
  24. www.sciencedirect.com www.sciencedirect.com
    Drug-repurposing screen on patient-derived organoids identifies therapy-induced vulnerability in KRAS-mutant colon cancer
    1
    1. scibot 06 Apr 2023
      RRID:AB_331701

      DOI: 10.1016/j.celrep.2023.112324

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    sciencedirect.com/science/article/pii/S2211124723003352
  25. Mar 2023
  26. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Loss of E-cadherin Induces IGF1R Activation and Reveals a Targetable Pathway in Invasive Lobular Breast Carcinoma
    1
    1. scibot 05 Mar 2023
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      DOI: 10.1158/1541-7786.MCR-22-0090

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    ncbi.nlm.nih.gov/pmc/articles/PMC9444924/
  27. Feb 2023
  28. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    IGF-binding proteins secreted by cancer-associated fibroblasts induce context-dependent drug sensitization of lung cancer cells
    1
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      DOI: 10.1126/scisignal.abj5879

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    ncbi.nlm.nih.gov/pmc/articles/PMC9528501/
  29. Jan 2023
  30. aacrjournals.org aacrjournals.org
    Loss of VOPP1 Contributes to BET Inhibitor Acquired Resistance in Non–Small Cell Lung Cancer Cells
    1
    1. scibot 14 Jan 2023
      RRID:AB_331701

      DOI: 10.1158/1541-7786.MCR-21-1000

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    aacrjournals.org/mcr/article/20/12/1785/710999/Loss-of-VOPP1-Contributes-to-BET-Inhibitor
  31. link.springer.com link.springer.com
    Cyclooxygenase-2 activates EGFR–ERK1/2 pathway via PGE2-mediated ADAM-17 signaling in testosterone-induced benign prostatic hyperplasia
    1
    1. scibot 04 Jan 2023
      AB_331701

      DOI: 10.1007/s10787-022-01123-7

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    link.springer.com/article/10.1007/s10787-022-01123-7
  32. Nov 2022
  33. www.sciencedirect.com www.sciencedirect.com
    Neuronal-epithelial cross-talk drives acinar specification via NRG1-ERBB3-mTORC2 signaling
    1
    1. scibot 22 Nov 2022
      RRID:AB_331701

      DOI: 10.1016/j.devcel.2022.10.011

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    sciencedirect.com/science/article/pii/S1534580722007638
  34. Sep 2022
  35. www.sciencedirect.com www.sciencedirect.com
    GABP couples oncogene signaling to telomere regulation in TERT promoter mutant cancer
    2
    1. scibot 22 Sep 2022
      RRID:AB_331701

      DOI: 10.1016/j.celrep.2022.111344

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      DOI: 10.1016/j.celrep.2022.111344

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    sciencedirect.com/science/article/pii/S221112472201172X
  36. Dec 2021
  37. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    In vivo efficacy of tesevatinib in patient-derived xenograft glioblastoma models may be limited by tissue binding and compensatory signaling
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    1. scibot 02 Dec 2021
      RRID:AB_331701

      DOI: 10.1158/1535-7163.MCT-20-0640

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    ncbi.nlm.nih.gov/pmc/articles/PMC8172524/
  38. Nov 2021
  39. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    AXL cooperates with EGFR to mediate neutrophil elastase-induced migration of prostate cancer cells
    1
    1. scibot 16 Nov 2021
      RRID:AB_331701

      DOI: 10.1016/j.isci.2021.103270

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    ncbi.nlm.nih.gov/pmc/articles/PMC8567381/
  40. Sep 2021
  41. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Establishment and genetic characterization of cell lines derived from proliferating nasal polyps and sinonasal inverted papillomas
    1
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      DOI: 10.1038/s41598-021-96444-y

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    ncbi.nlm.nih.gov/pmc/articles/PMC8384845/
  42. Aug 2021
  43. www.sciencedirect.com www.sciencedirect.com
    Functional diagnostics using fresh uncultured lung tumor cells to guide personalized treatments
    1
    1. scibot 18 Aug 2021
      RRID:AB_331701

      DOI: 10.1016/j.xcrm.2021.100373

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    sciencedirect.com/science/article/pii/S2666379121002275
  44. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Synthekines are surrogate cytokine and growth factor agonists that compel signaling through non-natural receptor dimers
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    1. scibot 10 Aug 2021
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      DOI: 10.7554/eLife.22882

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    ncbi.nlm.nih.gov/pmc/articles/PMC5429090/
  45. academic.oup.com academic.oup.com
    Untitled document
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    1. scibot 08 Aug 2021
      RRID:AB_331701

      DOI: 10.1210/js.2016-1053

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    academic.oup.com/jes/article/1/2/127/2930778
  46. www.sciencedirect.com www.sciencedirect.com
    Cellular Barcoding Identifies Clonal Substitution as a Hallmark of Local Recurrence in a Surgical Model of Head and Neck Squamous Cell Carcinoma
    1
    1. scibot 02 Aug 2021
      RRID:AB_331701

      DOI: 10.1016/j.celrep.2018.10.090

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    sciencedirect.com/science/article/pii/S2211124718316942
  47. Jul 2021
  48. www.sciencedirect.com www.sciencedirect.com
    Cellular Barcoding Identifies Clonal Substitution as a Hallmark of Local Recurrence in a Surgical Model of Head and Neck Squamous Cell Carcinoma
    1
    1. scibot 28 Jul 2021
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      DOI: 10.1016/j.celrep.2018.10.090

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    sciencedirect.com/science/article/pii/S2211124718316942
  49. Jun 2021
  50. www.sciencedirect.com www.sciencedirect.com
    Desmosomes polarize and integrate chemical and mechanical signaling to govern epidermal tissue form and function
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      DOI: 10.1016/j.cub.2021.05.021

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    sciencedirect.com/science/article/pii/S0960982221006801
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    Interactions between cancer cells and immune cells drive transitions to mesenchymal-like states in glioblastoma
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      DOI: 10.1016/j.ccell.2021.05.002

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    sciencedirect.com/science/article/pii/S1535610821002683
  52. May 2021
  53. www.sciencedirect.com www.sciencedirect.com
    PD-L1 recruits phospholipase C and enhances tumorigenicity of lung tumors harboring mutant forms of EGFR
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      DOI: 10.1016/j.celrep.2021.109181

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    sciencedirect.com/science/article/pii/S221112472100526X
  54. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    UBTD1 regulates ceramide balance and endolysosomal positioning to coordinate EGFR signaling
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      DOI: 10.7554/eLife.68348

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    ncbi.nlm.nih.gov/pmc/articles/PMC8118655/
  55. Apr 2021
  56. www.sciencedirect.com www.sciencedirect.com
    Cell Lineage-Based Stratification for Glioblastoma
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      DOI: 10.1016/j.ccell.2020.06.003

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    sciencedirect.com/science/article/pii/S153561082030307X
  57. www.sciencedirect.com www.sciencedirect.com
    Capturing human trophoblast development with naive pluripotent stem cells in vitro
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      DOI: 10.1016/j.stem.2021.03.013

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    sciencedirect.com/science/article/pii/S1934590921001193
  58. Sep 2020
  59. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    HSP90 Inhibitor, 17-DMAG, Alone and in Combination with Lapatinib Attenuates Acquired Lapatinib-Resistance in ER-positive, HER2-Overexpressing Breast Cancer Cell Line
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      DOI: 10.3390/cancers12092630

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    pubmed.ncbi.nlm.nih.gov/32942617/
  60. mcr.aacrjournals.org mcr.aacrjournals.org
    Dual Regulation of Histone Methylation by mTOR Complexes Controls Glioblastoma Tumor Cell Growth via EZH2 and SAM
    1
    1. scibot 03 Sep 2020
      p-EGFR

      DOI: 10.1158/1541-7786.MCR-20-0024

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    mcr.aacrjournals.org/content/18/8/1142
  61. Jan 2020
  62. www.sciencedirect.com www.sciencedirect.com
    Branched-Chain Amino Acid Metabolic Reprogramming Orchestrates Drug Resistance to EGFR Tyrosine Kinase Inhibitors
    1
    1. scibot 13 Jan 2020
      RRID:AB_331701

      DOI: 10.1016/j.celrep.2019.06.026

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    sciencedirect.com/science/article/pii/S2211124719307922
  63. Nov 2018
  64. www.sciencedirect.com www.sciencedirect.com
    Mechanism of Allosteric Coupling into and through the Plasma Membrane by EGFR
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      RRID:AB_331701

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    sciencedirect.com/science/article/pii/S2451945618301193
  65. www.sciencedirect.com www.sciencedirect.com
    EGFR-Phosphorylated Platelet Isoform of Phosphofructokinase 1 Promotes PI3K Activation
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      RRID:AB_331701

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    sciencedirect.com/science/article/pii/S1097276518302211
  66. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Epiregulin (EREG) is upregulated through an IL‐1β autocrine loop in Caco‐2 epithelial cells with reduced CFTR function
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    onlinelibrary.wiley.com/doi/10.1002/jcb.26483/full
  67. Nov 2017
  68. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Context Specificity in Causal Signaling Networks Revealed by Phosphoprotein Profiling
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    ncbi.nlm.nih.gov/pmc/articles/PMC5279869/
  69. www.sciencedirect.com www.sciencedirect.com
    EGFR Dynamics Change during Activation in Native Membranes as Revealed by NMR
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      2234S

      Curator: @Jmenke

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    sciencedirect.com/science/article/pii/S0092867416314593
  70. academic.oup.com academic.oup.com
    EGFR Induces E2F1-Mediated Corticotroph Tumorigenesis
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      AB_331701

      Curator: @chewbeccax

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      RRID:AB_331701 RRIDCUR:Validated
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    academic.oup.com/jes/article/1/2/127/2930778/EGFR-Induces-E2F1-Mediated-Corticotroph
  71. www.sciencedirect.com www.sciencedirect.com
    Context Specificity in Causal Signaling Networks Revealed by Phosphoprotein Profiling
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      AB_331701

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    sciencedirect.com/science/article/pii/S2405471216304082